"Factor VIIIa" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Activated form of factor VIII. The B-domain of factor VIII is proteolytically cleaved by thrombin to form factor VIIIa. Factor VIIIa exists as a non-covalent dimer in a metal-linked (probably calcium) complex and functions as a cofactor in the enzymatic activation of factor X by factor IXa. Factor VIIIa is similar in structure and generation to factor Va.
| Descriptor ID |
D015944
|
| MeSH Number(s) |
D12.776.124.125.350.300 D23.119.350.300
|
| Concept/Terms |
Factor VIIIa- Factor VIIIa
- Coagulation Factor VIIIa
- Factor VIIIa, Coagulation
- VIIIa, Coagulation Factor
- Factor VIII, Thrombin-Activated
- Factor VIII, Thrombin Activated
- Thrombin-Activated Factor VIII
- Blood Coagulation Factor VIII, Activated
- Factor VIII, Activated
- Activated Factor VIII
|
Below are MeSH descriptors whose meaning is more general than "Factor VIIIa".
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