Phosphofructokinase-1, Muscle Type
"Phosphofructokinase-1, Muscle Type" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
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An allosteric enzyme that regulates glycolysis by catalyzing the transfer of a phosphate group from ATP to fructose-6-phosphate to yield fructose-1,6-bisphosphate. In humans, PHOSPHOFRUCTOKINASE-1 in muscle exists as the homotetramer of M subunits. Defects in this muscle enzyme cause GLYCOGEN STORAGE DISEASE TYPE VII, also known as Tarui's disease.
Descriptor ID |
D025203
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MeSH Number(s) |
D08.811.913.696.620.225.850.500.500
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Concept/Terms |
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