Specialized Fc receptors (RECEPTORS, FC) for polymeric immunoglobulins, which mediate transcytosis of polymeric IMMUNOGLOBULIN A and IMMUNOGLOBULIN M into external secretions. They are found on the surfaces of epithelial cells and hepatocytes. After binding to IMMUNOGLOBULIN A, the receptor-ligand complex undergoes endocytosis, transport by vesicle, and secretion into the lumen by exocytosis. Before release, the part of the receptor (SECRETORY COMPONENT) that is bound to IMMUNOGLOBULIN A is proteolytically cleaved from its transmembrane tail. (From Rosen et al., The Dictionary of Immunology, 1989)

Descriptor ID	D019056
MeSH Number(s)	D12.776.543.750.705.871.700
Concept/Terms	Receptors, Polymeric Immunoglobulin Receptors, Polymeric Immunoglobulin Polymeric Immunoglobulin Receptors Immunoglobulin Receptors, Polymeric Receptor, Polyimmunoglobulin Receptor, Polymeric Ig Poly-Ig Receptor Poly Ig Receptor Receptor, Poly-Ig Polyimmunoglobulin Receptor Polymeric Immunoglobulin Receptor Immunoglobulin Receptor, Polymeric Receptor, Polymeric Immunoglobulin Polymeric Ig Receptor Ig Receptor, Polymeric

Below are MeSH descriptors whose meaning is more general than "Receptors, Polymeric Immunoglobulin".

Below are MeSH descriptors whose meaning is related to "Receptors, Polymeric Immunoglobulin".

Below are MeSH descriptors whose meaning is more specific than "Receptors, Polymeric Immunoglobulin".