"RNA-Binding Protein FUS" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A multifunctional heterogeneous-nuclear ribonucleoprotein that may play a role in homologous DNA pairing and recombination. The N-terminal portion of protein is a potent transcriptional activator, while the C terminus is required for RNA binding. The name FUS refers to the fact that genetic recombination events result in fusion oncogene proteins (ONCOGENE PROTEINS, FUSION) that contain the N-terminal region of this protein. These fusion proteins have been found in myxoid liposarcoma (LIPOSARCOMA, MYXOID) and acute myeloid leukemia.
| Descriptor ID |
D034702
|
| MeSH Number(s) |
D12.776.157.725.500.500.905 D12.776.624.664.700.915 D12.776.664.962.500.500.902
|
| Concept/Terms |
RNA-Binding Protein FUS- RNA-Binding Protein FUS
- RNA Binding Protein FUS
- TLS Protein
- hnRNP P2
- POMp75 Protein
- Translocated in Liposarcoma Protein
- FUS RNA-Binding Protein
- FUS RNA Binding Protein
- RNA-Binding Protein, FUS
- Fusion Protein in Myxoid Liposarcoma
- FUS Protein
|
Below are MeSH descriptors whose meaning is more general than "RNA-Binding Protein FUS".
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