Enhanced functional recombinant factor VII production by HEK 293 cells stably transfected with VKORC1 where the gamma-carboxylase inhibitor calumenin is stably suppressed by shRNA transfection.

Wajih N, Owen J, Wallin R. Enhanced functional recombinant factor VII production by HEK 293 cells stably transfected with VKORC1 where the gamma-carboxylase inhibitor calumenin is stably suppressed by shRNA transfection. Thromb Res. 2008; 122(3):405-10.

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subject areas

Animals
Calcium-Binding Proteins
Cell Line
Cloning, Molecular
Factor VII
Gene Expression Regulation, Enzymologic
Humans
Kidney
Mixed Function Oxygenases
Plasmids
Protein Engineering
Rats
Recombinant Proteins
RNA Interference
Transfection

authors with profiles

John Owen MD