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Flt3-ITD alters chemotherapy response in vitro and in vivo in a p53-dependent manner.
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Flt3-ITD alters chemotherapy response in vitro and in vivo in a p53-dependent manner.
Pardee TS, Zuber J, Lowe SW. Flt3-ITD alters chemotherapy response in vitro and in vivo in a p53-dependent manner. Exp Hematol. 2011 Apr; 39(4):473-485.e4.
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PubMed
subject areas
Acute Disease
Animals
Antineoplastic Combined Chemotherapy Protocols
Benzenesulfonates
Blotting, Western
Cytarabine
Disease Models, Animal
DNA Damage
Doxorubicin
Drug Resistance, Neoplasm
fms-Like Tyrosine Kinase 3
Gene Duplication
Humans
Leukemia, Myeloid
Mice
Mice, Inbred C57BL
Mice, Transgenic
Myeloid-Lymphoid Leukemia Protein
Niacinamide
Phenylurea Compounds
Pyridines
Reverse Transcriptase Polymerase Chain Reaction
RNA Interference
Survival Analysis
Tandem Repeat Sequences
Tumor Suppressor Protein p53
authors with profiles
Timothy S. Pardee MD, PhD