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Does lidocaine more effectively prevent pain upon induction with propofol or etomidate when given preemptively than when mixed with the drug?

Brock MF, Grace BE, Morley B, Hillegass G, Houle TT, Groban L. Does lidocaine more effectively prevent pain upon induction with propofol or etomidate when given preemptively than when mixed with the drug? J Clin Anesth. 2010 Nov; 22(7):505-9.

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