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Connection

Yusuke Takahashi to cis-trans-Isomerases

This is a "connection" page, showing publications Yusuke Takahashi has written about cis-trans-Isomerases.
Connection Strength

3.171
  1. Takahashi Y, Moiseyev G, Ma JX. Identification of key residues determining isomerohydrolase activity of human RPE65. J Biol Chem. 2014 Sep 26; 289(39):26743-26751.
    View in: PubMed
    Score: 0.472
  2. Takahashi Y, Moiseyev G, Nikolaeva O, Ma JX. Identification of the key residues determining the product specificity of isomerohydrolase. Biochemistry. 2012 May 22; 51(20):4217-25.
    View in: PubMed
    Score: 0.404
  3. Takahashi Y, Moiseyev G, Chen Y, Nikolaeva O, Ma JX. An alternative isomerohydrolase in the retinal Müller cells of a cone-dominant species. FEBS J. 2011 Aug; 278(16):2913-26.
    View in: PubMed
    Score: 0.380
  4. Takahashi Y, Moiseyev G, Chen Y, Farjo K, Nikolaeva O, Ma JX. An enzymatic mechanism for generating the precursor of endogenous 13-cis retinoic acid in the brain. FEBS J. 2011 Apr; 278(6):973-87.
    View in: PubMed
    Score: 0.370
  5. Takahashi Y, Moiseyev G, Chen Y, Ma JX. The roles of three palmitoylation sites of RPE65 in its membrane association and isomerohydrolase activity. Invest Ophthalmol Vis Sci. 2006 Dec; 47(12):5191-6.
    View in: PubMed
    Score: 0.277
  6. Takahashi Y, Chen Y, Moiseyev G, Ma JX. Two point mutations of RPE65 from patients with retinal dystrophies decrease the stability of RPE65 protein and abolish its isomerohydrolase activity. J Biol Chem. 2006 Aug 04; 281(31):21820-21826.
    View in: PubMed
    Score: 0.268
  7. Wu W, Takahashi Y, Shin HY, Ma X, Moiseyev G, Ma JX. The interplay of environmental luminance and genetics in the retinal dystrophy induced by the dominant RPE65 mutation. Proc Natl Acad Sci U S A. 2022 Mar 15; 119(11):e2115202119.
    View in: PubMed
    Score: 0.199
  8. Shin Y, Moiseyev G, Petrukhin K, Cioffi CL, Muthuraman P, Takahashi Y, Ma JX. A novel RPE65 inhibitor CU239 suppresses visual cycle and prevents retinal degeneration. Biochim Biophys Acta Mol Basis Dis. 2018 Jul; 1864(7):2420-2429.
    View in: PubMed
    Score: 0.152
  9. Nikolaeva O, Takahashi Y, Moiseyev G, Ma JX. Negative charge of the glutamic acid 417 residue is crucial for isomerohydrolase activity of RPE65. Biochem Biophys Res Commun. 2010 Jan 22; 391(4):1757-61.
    View in: PubMed
    Score: 0.086
  10. Nikolaeva O, Takahashi Y, Moiseyev G, Ma JX. Purified RPE65 shows isomerohydrolase activity after reassociation with a phospholipid membrane. FEBS J. 2009 Jun; 276(11):3020-30.
    View in: PubMed
    Score: 0.082
  11. Takahashi Y, Moiseyev G, Ablonczy Z, Chen Y, Crouch RK, Ma JX. Identification of a novel palmitylation site essential for membrane association and isomerohydrolase activity of RPE65. J Biol Chem. 2009 Jan 30; 284(5):3211-3218.
    View in: PubMed
    Score: 0.079
  12. Moiseyev G, Takahashi Y, Chen Y, Kim S, Ma JX. RPE65 from cone-dominant chicken is a more efficient isomerohydrolase compared with that from rod-dominant species. J Biol Chem. 2008 Mar 28; 283(13):8110-7.
    View in: PubMed
    Score: 0.075
  13. Chen Y, Moiseyev G, Takahashi Y, Ma JX. Impacts of two point mutations of RPE65 from Leber's congenital amaurosis on the stability, subcellular localization and isomerohydrolase activity of RPE65. FEBS Lett. 2006 Jul 24; 580(17):4200-4.
    View in: PubMed
    Score: 0.067
  14. Chen Y, Moiseyev G, Takahashi Y, Ma JX. RPE65 gene delivery restores isomerohydrolase activity and prevents early cone loss in Rpe65-/- mice. Invest Ophthalmol Vis Sci. 2006 Mar; 47(3):1177-84.
    View in: PubMed
    Score: 0.066
  15. Takahashi Y, Moiseyev G, Chen Y, Ma JX. Identification of conserved histidines and glutamic acid as key residues for isomerohydrolase activity of RPE65, an enzyme of the visual cycle in the retinal pigment epithelium. FEBS Lett. 2005 Oct 10; 579(24):5414-8.
    View in: PubMed
    Score: 0.064
  16. Moiseyev G, Chen Y, Takahashi Y, Wu BX, Ma JX. RPE65 is the isomerohydrolase in the retinoid visual cycle. Proc Natl Acad Sci U S A. 2005 Aug 30; 102(35):12413-8.
    View in: PubMed
    Score: 0.063
  17. Hu Y, Chen Y, Moiseyev G, Takahashi Y, Mott R, Ma JX. Comparison of ocular pathologies in vitamin A-deficient mice and RPE65 gene knockout mice. Invest Ophthalmol Vis Sci. 2011 Jul 25; 52(8):5507-14.
    View in: PubMed
    Score: 0.024
  18. Moiseyev G, Nikolaeva O, Chen Y, Farjo K, Takahashi Y, Ma JX. Inhibition of the visual cycle by A2E through direct interaction with RPE65 and implications in Stargardt disease. Proc Natl Acad Sci U S A. 2010 Oct 12; 107(41):17551-6.
    View in: PubMed
    Score: 0.023
  19. Farjo KM, Moiseyev G, Takahashi Y, Crouch RK, Ma JX. The 11-cis-retinol dehydrogenase activity of RDH10 and its interaction with visual cycle proteins. Invest Ophthalmol Vis Sci. 2009 Nov; 50(11):5089-97.
    View in: PubMed
    Score: 0.021
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.