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Yusuke Takahashi to Animals

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This is a "connection" page, showing publications Yusuke Takahashi has written about Animals.
Yusuke Takahashi
Connection Strength
0.981
Animals
  1. Ma X, Wu W, Hara M, Zhou J, Panzarin C, Schafer CM, Griffin CT, Cai J, Ma JX, Takahashi Y. Deficient RPE mitochondrial energetics leads to subretinal fibrosis in age-related neovascular macular degeneration. Commun Biol. 2024 Sep 02; 7(1):1075.
    View in: PubMed
    Score: 0.097
  2. Singh HD, Ma JX, Takahashi Y. Distinct roles of LRP5 and LRP6 in Wnt signaling regulation in the retina. Biochem Biophys Res Commun. 2021 Mar 19; 545:8-13.
    View in: PubMed
    Score: 0.076
  3. Takahashi Y, Chen Q, Rajala RVS, Ma JX. MicroRNA-184 modulates canonical Wnt signaling through the regulation of frizzled-7 expression in the retina with ischemia-induced neovascularization. FEBS Lett. 2015 Apr 28; 589(10):1143-1149.
    View in: PubMed
    Score: 0.051
  4. Takahashi Y, Moiseyev G, Ma JX. Identification of key residues determining isomerohydrolase activity of human RPE65. J Biol Chem. 2014 Sep 26; 289(39):26743-26751.
    View in: PubMed
    Score: 0.048
  5. Takahashi Y, Moiseyev G, Nikolaeva O, Ma JX. Identification of the key residues determining the product specificity of isomerohydrolase. Biochemistry. 2012 May 22; 51(20):4217-25.
    View in: PubMed
    Score: 0.041
  6. Takahashi Y, Moiseyev G, Chen Y, Nikolaeva O, Ma JX. An alternative isomerohydrolase in the retinal Müller cells of a cone-dominant species. FEBS J. 2011 Aug; 278(16):2913-26.
    View in: PubMed
    Score: 0.039
  7. Takahashi Y, Moiseyev G, Chen Y, Farjo K, Nikolaeva O, Ma JX. An enzymatic mechanism for generating the precursor of endogenous 13-cis retinoic acid in the brain. FEBS J. 2011 Apr; 278(6):973-87.
    View in: PubMed
    Score: 0.038
  8. Takahashi Y, Moiseyev G, Farjo K, Ma JX. Characterization of key residues and membrane association domains in retinol dehydrogenase 10. Biochem J. 2009 Apr 01; 419(1):113-22, 1 p following 122.
    View in: PubMed
    Score: 0.033
  9. Takahashi Y, Moiseyev G, Ablonczy Z, Chen Y, Crouch RK, Ma JX. Identification of a novel palmitylation site essential for membrane association and isomerohydrolase activity of RPE65. J Biol Chem. 2009 Jan 30; 284(5):3211-3218.
    View in: PubMed
    Score: 0.033
  10. Takahashi Y, Chen Y, Moiseyev G, Ma JX. Two point mutations of RPE65 from patients with retinal dystrophies decrease the stability of RPE65 protein and abolish its isomerohydrolase activity. J Biol Chem. 2006 Aug 04; 281(31):21820-21826.
    View in: PubMed
    Score: 0.027
  11. Takahashi Y, Yokoyama S. Genetic basis of spectral tuning in the violet-sensitive visual pigment of African clawed frog, Xenopus laevis. Genetics. 2005 Nov; 171(3):1153-60.
    View in: PubMed
    Score: 0.026
  12. Liang W, Huang L, Yuan T, Cheng R, Takahashi Y, Moiseyev GP, Karamichos D, Ma JX. A Method for Real-Time Assessment of Mitochondrial Respiration Using Murine Corneal Biopsy. Invest Ophthalmol Vis Sci. 2023 Aug 01; 64(11):33.
    View in: PubMed
    Score: 0.023
  13. Takahashi Y, Ebrey TG. Molecular basis of spectral tuning in the newt short wavelength sensitive visual pigment. Biochemistry. 2003 May 27; 42(20):6025-34.
    View in: PubMed
    Score: 0.022
  14. Liang W, Huang L, Whelchel A, Yuan T, Ma X, Cheng R, Takahashi Y, Karamichos D, Ma JX. Peroxisome proliferator-activated receptor-a (PPARa) regulates wound healing and mitochondrial metabolism in the cornea. Proc Natl Acad Sci U S A. 2023 Mar 28; 120(13):e2217576120.
    View in: PubMed
    Score: 0.022
  15. Wu W, Takahashi Y, Ma X, Moiseyev G, Ma JX. Environmental Light Has an Essential Effect on the Disease Expression in a Dominant RPE65 Mutation. Adv Exp Med Biol. 2023; 1415:415-419.
    View in: PubMed
    Score: 0.022
  16. Ma X, Wu W, Liang W, Takahashi Y, Cai J, Ma JX. Modulation of cGAS-STING signaling by PPARa in a mouse model of ischemia-induced retinopathy. Proc Natl Acad Sci U S A. 2022 Nov 29; 119(48):e2208934119.
    View in: PubMed
    Score: 0.022
  17. Wu W, Takahashi Y, Shin HY, Ma X, Moiseyev G, Ma JX. The interplay of environmental luminance and genetics in the retinal dystrophy induced by the dominant RPE65 mutation. Proc Natl Acad Sci U S A. 2022 Mar 15; 119(11):e2115202119.
    View in: PubMed
    Score: 0.020
  18. Ma X, Takahashi Y, Wu W, Chen J, Dehdarani M, Liang W, Shin YH, Benyajati S, Ma JX. Soluble very low-density lipoprotein receptor (sVLDLR) inhibits fibrosis in neovascular age-related macular degeneration. FASEB J. 2021 Dec; 35(12):e22058.
    View in: PubMed
    Score: 0.020
  19. Ma X, Takahashi Y, Wu W, Liang W, Chen J, Chakraborty D, Li Y, Du Y, Benyajati S, Ma JX. ADAM17 mediates ectodomain shedding of the soluble VLDL receptor fragment in the retinal epithelium. J Biol Chem. 2021 Oct; 297(4):101185.
    View in: PubMed
    Score: 0.020
  20. Takahashi Y, Hisatomi O, Sakakibara S, Tokunaga F, Tsukahara Y. Distribution of blue-sensitive photoreceptors in amphibian retinas. FEBS Lett. 2001 Jul 20; 501(2-3):151-5.
    View in: PubMed
    Score: 0.020
  21. He X, Cheng R, Huang C, Takahashi Y, Yang Y, Benyajati S, Chen Y, Zhang XA, Ma JX. A novel role of LRP5 in tubulointerstitial fibrosis through activating TGF-ß/Smad signaling. Signal Transduct Target Ther. 2020 Apr 29; 5(1):45.
    View in: PubMed
    Score: 0.018
  22. Shao Y, Dong LJ, Takahashi Y, Chen J, Liu X, Chen Q, Ma JX, Li XR. miRNA-451a regulates RPE function through promoting mitochondrial function in proliferative diabetic retinopathy. Am J Physiol Endocrinol Metab. 2019 Mar 01; 316(3):E443-E452.
    View in: PubMed
    Score: 0.016
  23. Shin Y, Moiseyev G, Petrukhin K, Cioffi CL, Muthuraman P, Takahashi Y, Ma JX. A novel RPE65 inhibitor CU239 suppresses visual cycle and prevents retinal degeneration. Biochim Biophys Acta Mol Basis Dis. 2018 Jul; 1864(7):2420-2429.
    View in: PubMed
    Score: 0.016
  24. Pearsall EA, Cheng R, Zhou K, Takahashi Y, Matlock HG, Vadvalkar SS, Shin Y, Fredrick TW, Gantner ML, Meng S, Fu Z, Gong Y, Kinter M, Humphries KM, Szweda LI, Smith LEH, Ma JX. PPARa is essential for retinal lipid metabolism and neuronal survival. BMC Biol. 2017 Nov 28; 15(1):113.
    View in: PubMed
    Score: 0.015
  25. Malechka VV, Moiseyev G, Takahashi Y, Shin Y, Ma JX. Impaired Rhodopsin Generation in the Rat Model of Diabetic Retinopathy. Am J Pathol. 2017 Oct; 187(10):2222-2231.
    View in: PubMed
    Score: 0.015
  26. Chen Q, Qiu F, Zhou K, Matlock HG, Takahashi Y, Rajala RVS, Yang Y, Moran E, Ma JX. Pathogenic Role of microRNA-21 in Diabetic Retinopathy Through Downregulation of PPARa. Diabetes. 2017 Jun; 66(6):1671-1682.
    View in: PubMed
    Score: 0.014
  27. Chen Q, Takahashi Y, Oka K, Ma JX. Functional Differences of Very-Low-Density Lipoprotein Receptor Splice Variants in Regulating Wnt Signaling. Mol Cell Biol. 2016 Oct 15; 36(20):2645-54.
    View in: PubMed
    Score: 0.014
  28. Cheng R, Ding L, He X, Takahashi Y, Ma JX. Interaction of PPARa With the Canonic Wnt Pathway in the Regulation of Renal Fibrosis. Diabetes. 2016 Dec; 65(12):3730-3743.
    View in: PubMed
    Score: 0.014
  29. Lee K, Shin Y, Cheng R, Park K, Hu Y, McBride J, He X, Takahashi Y, Ma JX. Receptor heterodimerization as a novel mechanism for the regulation of Wnt/ß-catenin signaling. J Cell Sci. 2014 Nov 15; 127(Pt 22):4857-69.
    View in: PubMed
    Score: 0.012
  30. Ding L, Cheng R, Hu Y, Takahashi Y, Jenkins AJ, Keech AC, Humphries KM, Gu X, Elliott MH, Xia X, Ma JX. Peroxisome proliferator-activated receptor a protects capillary pericytes in the retina. Am J Pathol. 2014 Oct; 184(10):2709-20.
    View in: PubMed
    Score: 0.012
  31. Moran E, Ding L, Wang Z, Cheng R, Chen Q, Moore R, Takahashi Y, Ma JX. Protective and antioxidant effects of PPARa in the ischemic retina. Invest Ophthalmol Vis Sci. 2014 May 13; 55(7):4568-76.
    View in: PubMed
    Score: 0.012
  32. Hu Y, Chen Y, Ding L, He X, Takahashi Y, Gao Y, Shen W, Cheng R, Chen Q, Qi X, Boulton ME, Ma JX. Pathogenic role of diabetes-induced PPAR-a down-regulation in microvascular dysfunction. Proc Natl Acad Sci U S A. 2013 Sep 17; 110(38):15401-6.
    View in: PubMed
    Score: 0.011
  33. Murray AR, Chen Q, Takahashi Y, Zhou KK, Park K, Ma JX. MicroRNA-200b downregulates oxidation resistance 1 (Oxr1) expression in the retina of type 1 diabetes model. Invest Ophthalmol Vis Sci. 2013 Mar 05; 54(3):1689-97.
    View in: PubMed
    Score: 0.011
  34. Lee K, Hu Y, Ding L, Chen Y, Takahashi Y, Mott R, Ma JX. Therapeutic potential of a monoclonal antibody blocking the Wnt pathway in diabetic retinopathy. Diabetes. 2012 Nov; 61(11):2948-57.
    View in: PubMed
    Score: 0.011
  35. Zhou T, He X, Cheng R, Zhang B, Zhang RR, Chen Y, Takahashi Y, Murray AR, Lee K, Gao G, Ma JX. Implication of dysregulation of the canonical wingless-type MMTV integration site (WNT) pathway in diabetic nephropathy. Diabetologia. 2012 Jan; 55(1):255-66.
    View in: PubMed
    Score: 0.010
  36. Hu Y, Chen Y, Moiseyev G, Takahashi Y, Mott R, Ma JX. Comparison of ocular pathologies in vitamin A-deficient mice and RPE65 gene knockout mice. Invest Ophthalmol Vis Sci. 2011 Jul 25; 52(8):5507-14.
    View in: PubMed
    Score: 0.010
  37. Moiseyev G, Nikolaeva O, Chen Y, Farjo K, Takahashi Y, Ma JX. Inhibition of the visual cycle by A2E through direct interaction with RPE65 and implications in Stargardt disease. Proc Natl Acad Sci U S A. 2010 Oct 12; 107(41):17551-6.
    View in: PubMed
    Score: 0.009
  38. Farjo KM, Moiseyev G, Takahashi Y, Crouch RK, Ma JX. The 11-cis-retinol dehydrogenase activity of RDH10 and its interaction with visual cycle proteins. Invest Ophthalmol Vis Sci. 2009 Nov; 50(11):5089-97.
    View in: PubMed
    Score: 0.008
  39. Nikolaeva O, Takahashi Y, Moiseyev G, Ma JX. Purified RPE65 shows isomerohydrolase activity after reassociation with a phospholipid membrane. FEBS J. 2009 Jun; 276(11):3020-30.
    View in: PubMed
    Score: 0.008
  40. Moiseyev G, Takahashi Y, Chen Y, Kim S, Ma JX. RPE65 from cone-dominant chicken is a more efficient isomerohydrolase compared with that from rod-dominant species. J Biol Chem. 2008 Mar 28; 283(13):8110-7.
    View in: PubMed
    Score: 0.008
  41. Chen Y, Moiseyev G, Takahashi Y, Ma JX. RPE65 gene delivery restores isomerohydrolase activity and prevents early cone loss in Rpe65-/- mice. Invest Ophthalmol Vis Sci. 2006 Mar; 47(3):1177-84.
    View in: PubMed
    Score: 0.007
  42. Yokoyama S, Starmer WT, Takahashi Y, Tada T. Tertiary structure and spectral tuning of UV and violet pigments in vertebrates. Gene. 2006 Jan 03; 365:95-103.
    View in: PubMed
    Score: 0.007
  43. Moiseyev G, Takahashi Y, Chen Y, Gentleman S, Redmond TM, Crouch RK, Ma JX. RPE65 is an iron(II)-dependent isomerohydrolase in the retinoid visual cycle. J Biol Chem. 2006 Feb 03; 281(5):2835-40.
    View in: PubMed
    Score: 0.007
  44. Moiseyev G, Chen Y, Takahashi Y, Wu BX, Ma JX. RPE65 is the isomerohydrolase in the retinoid visual cycle. Proc Natl Acad Sci U S A. 2005 Aug 30; 102(35):12413-8.
    View in: PubMed
    Score: 0.007
  45. Sakakibara S, Hiramatsu H, Takahashi Y, Hisatomi O, Kobayashi Y, Sakami S, Saito T, Tokunaga F. Opsin expression in adult, developing, and regenerating newt retinas. Brain Res Mol Brain Res. 2002 Jun 30; 103(1-2):28-35.
    View in: PubMed
    Score: 0.005
  46. Hisatomi O, Takahashi Y, Taniguchi Y, Tsukahara Y, Tokunaga F. Primary structure of a visual pigment in bullfrog green rods. FEBS Lett. 1999 Mar 19; 447(1):44-8.
    View in: PubMed
    Score: 0.004
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