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Connection

Yusuke Takahashi to Humans

This is a "connection" page, showing publications Yusuke Takahashi has written about Humans.
Connection Strength

0.280
  1. Singh HD, Ma JX, Takahashi Y. Distinct roles of LRP5 and LRP6 in Wnt signaling regulation in the retina. Biochem Biophys Res Commun. 2021 Mar 19; 545:8-13.
    View in: PubMed
    Score: 0.041
  2. Takahashi Y, Moiseyev G, Ma JX. Identification of key residues determining isomerohydrolase activity of human RPE65. J Biol Chem. 2014 Sep 26; 289(39):26743-26751.
    View in: PubMed
    Score: 0.026
  3. Takahashi Y, Moiseyev G, Chen Y, Farjo K, Nikolaeva O, Ma JX. An enzymatic mechanism for generating the precursor of endogenous 13-cis retinoic acid in the brain. FEBS J. 2011 Apr; 278(6):973-87.
    View in: PubMed
    Score: 0.020
  4. Takahashi Y, Moiseyev G, Farjo K, Ma JX. Characterization of key residues and membrane association domains in retinol dehydrogenase 10. Biochem J. 2009 Apr 01; 419(1):113-22, 1 p following 122.
    View in: PubMed
    Score: 0.018
  5. Takahashi Y, Moiseyev G, Ablonczy Z, Chen Y, Crouch RK, Ma JX. Identification of a novel palmitylation site essential for membrane association and isomerohydrolase activity of RPE65. J Biol Chem. 2009 Jan 30; 284(5):3211-3218.
    View in: PubMed
    Score: 0.017
  6. Takahashi Y, Moiseyev G, Chen Y, Ma JX. The roles of three palmitoylation sites of RPE65 in its membrane association and isomerohydrolase activity. Invest Ophthalmol Vis Sci. 2006 Dec; 47(12):5191-6.
    View in: PubMed
    Score: 0.015
  7. Takahashi Y, Chen Y, Moiseyev G, Ma JX. Two point mutations of RPE65 from patients with retinal dystrophies decrease the stability of RPE65 protein and abolish its isomerohydrolase activity. J Biol Chem. 2006 Aug 04; 281(31):21820-21826.
    View in: PubMed
    Score: 0.015
  8. Takahashi Y, Moiseyev G, Chen Y, Ma JX. Identification of conserved histidines and glutamic acid as key residues for isomerohydrolase activity of RPE65, an enzyme of the visual cycle in the retinal pigment epithelium. FEBS Lett. 2005 Oct 10; 579(24):5414-8.
    View in: PubMed
    Score: 0.014
  9. Liang W, Huang L, Whelchel A, Yuan T, Ma X, Cheng R, Takahashi Y, Karamichos D, Ma JX. Peroxisome proliferator-activated receptor-a (PPARa) regulates wound healing and mitochondrial metabolism in the cornea. Proc Natl Acad Sci U S A. 2023 Mar 28; 120(13):e2217576120.
    View in: PubMed
    Score: 0.012
  10. Ma X, Takahashi Y, Wu W, Liang W, Chen J, Chakraborty D, Li Y, Du Y, Benyajati S, Ma JX. ADAM17 mediates ectodomain shedding of the soluble VLDL receptor fragment in the retinal epithelium. J Biol Chem. 2021 Oct; 297(4):101185.
    View in: PubMed
    Score: 0.011
  11. Shao Y, Dong LJ, Takahashi Y, Chen J, Liu X, Chen Q, Ma JX, Li XR. miRNA-451a regulates RPE function through promoting mitochondrial function in proliferative diabetic retinopathy. Am J Physiol Endocrinol Metab. 2019 Mar 01; 316(3):E443-E452.
    View in: PubMed
    Score: 0.009
  12. Chen Q, Qiu F, Zhou K, Matlock HG, Takahashi Y, Rajala RVS, Yang Y, Moran E, Ma JX. Pathogenic Role of microRNA-21 in Diabetic Retinopathy Through Downregulation of PPARa. Diabetes. 2017 Jun; 66(6):1671-1682.
    View in: PubMed
    Score: 0.008
  13. Chen Q, Takahashi Y, Oka K, Ma JX. Functional Differences of Very-Low-Density Lipoprotein Receptor Splice Variants in Regulating Wnt Signaling. Mol Cell Biol. 2016 Oct 15; 36(20):2645-54.
    View in: PubMed
    Score: 0.007
  14. Tryggestad JB, Vishwanath A, Jiang S, Mallappa A, Teague AM, Takahashi Y, Thompson DM, Chernausek SD. Influence of gestational diabetes mellitus on human umbilical vein endothelial cell miRNA. Clin Sci (Lond). 2016 Nov 01; 130(21):1955-67.
    View in: PubMed
    Score: 0.007
  15. Cheng R, Ding L, He X, Takahashi Y, Ma JX. Interaction of PPARa With the Canonic Wnt Pathway in the Regulation of Renal Fibrosis. Diabetes. 2016 Dec; 65(12):3730-3743.
    View in: PubMed
    Score: 0.007
  16. Lee K, Shin Y, Cheng R, Park K, Hu Y, McBride J, He X, Takahashi Y, Ma JX. Receptor heterodimerization as a novel mechanism for the regulation of Wnt/ß-catenin signaling. J Cell Sci. 2014 Nov 15; 127(Pt 22):4857-69.
    View in: PubMed
    Score: 0.007
  17. Ding L, Cheng R, Hu Y, Takahashi Y, Jenkins AJ, Keech AC, Humphries KM, Gu X, Elliott MH, Xia X, Ma JX. Peroxisome proliferator-activated receptor a protects capillary pericytes in the retina. Am J Pathol. 2014 Oct; 184(10):2709-20.
    View in: PubMed
    Score: 0.006
  18. Lee K, Hu Y, Ding L, Chen Y, Takahashi Y, Mott R, Ma JX. Therapeutic potential of a monoclonal antibody blocking the Wnt pathway in diabetic retinopathy. Diabetes. 2012 Nov; 61(11):2948-57.
    View in: PubMed
    Score: 0.006
  19. Zhou T, He X, Cheng R, Zhang B, Zhang RR, Chen Y, Takahashi Y, Murray AR, Lee K, Gao G, Ma JX. Implication of dysregulation of the canonical wingless-type MMTV integration site (WNT) pathway in diabetic nephropathy. Diabetologia. 2012 Jan; 55(1):255-66.
    View in: PubMed
    Score: 0.005
  20. Nikolaeva O, Takahashi Y, Moiseyev G, Ma JX. Negative charge of the glutamic acid 417 residue is crucial for isomerohydrolase activity of RPE65. Biochem Biophys Res Commun. 2010 Jan 22; 391(4):1757-61.
    View in: PubMed
    Score: 0.005
  21. Farjo KM, Moiseyev G, Takahashi Y, Crouch RK, Ma JX. The 11-cis-retinol dehydrogenase activity of RDH10 and its interaction with visual cycle proteins. Invest Ophthalmol Vis Sci. 2009 Nov; 50(11):5089-97.
    View in: PubMed
    Score: 0.005
  22. Nikolaeva O, Takahashi Y, Moiseyev G, Ma JX. Purified RPE65 shows isomerohydrolase activity after reassociation with a phospholipid membrane. FEBS J. 2009 Jun; 276(11):3020-30.
    View in: PubMed
    Score: 0.004
  23. Moiseyev G, Takahashi Y, Chen Y, Kim S, Ma JX. RPE65 from cone-dominant chicken is a more efficient isomerohydrolase compared with that from rod-dominant species. J Biol Chem. 2008 Mar 28; 283(13):8110-7.
    View in: PubMed
    Score: 0.004
  24. Chen Y, Moiseyev G, Takahashi Y, Ma JX. Impacts of two point mutations of RPE65 from Leber's congenital amaurosis on the stability, subcellular localization and isomerohydrolase activity of RPE65. FEBS Lett. 2006 Jul 24; 580(17):4200-4.
    View in: PubMed
    Score: 0.004
  25. Chen Y, Moiseyev G, Takahashi Y, Ma JX. RPE65 gene delivery restores isomerohydrolase activity and prevents early cone loss in Rpe65-/- mice. Invest Ophthalmol Vis Sci. 2006 Mar; 47(3):1177-84.
    View in: PubMed
    Score: 0.004
  26. Moiseyev G, Chen Y, Takahashi Y, Wu BX, Ma JX. RPE65 is the isomerohydrolase in the retinoid visual cycle. Proc Natl Acad Sci U S A. 2005 Aug 30; 102(35):12413-8.
    View in: PubMed
    Score: 0.003
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.