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Haodong Xu MD, PhD

TitleProfessor
InstitutionWake Forest School of Medicine
DepartmentPathology
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    Other Positions
    TitleDirector
    InstitutionWake Forest School of Medicine

    TitleProfessor
    InstitutionWake Forest School of Medicine
    DepartmentInternal Medicine, Cardiovascular Medicine


    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Hu CC, Wei X, Liu JM, Han LL, Xia CK, Wu J, You T, Zhu AF, Yao SL, Yuan SY, Xu HD, Xia ZY, Wang TT, Mao WK. Cardiac-targeted PIASy gene silencing mediates deSUMOylation of caveolin-3 and prevents ischemia/reperfusion-induced Nav1.5 downregulation and ventricular arrhythmias. Mil Med Res. 2022 Oct 14; 9(1):58. PMID: 36229865.
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    2. Wang P, Xu S, Xu J, Xin Y, Lu Y, Zhang H, Zhou B, Xu H, Sheu SS, Tian R, Wang W. Elevated MCU Expression by CaMKIIdB Limits Pathological Cardiac Remodeling. Circulation. 2022 Apr 05; 145(14):1067-1083. PMID: 35167328.
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    3. Zhao L, You T, Lu Y, Lin S, Li F, Xu H. Elevated EZH2 in ischemic heart disease epigenetically mediates suppression of NaV1.5 expression. J Mol Cell Cardiol. 2021 Apr; 153:95-103. PMID: 33370552.
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    4. Bradley BT, Maioli H, Johnston R, Chaudhry I, Fink SL, Xu H, Najafian B, Deutsch G, Lacy JM, Williams T, Yarid N, Marshall DA. Histopathology and ultrastructural findings of fatal COVID-19 infections in Washington State: a case series. Lancet. 2020 Aug 01; 396(10247):320-332. PMID: 32682491.
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    5. Mantilla JG, Xu H, Ricciotti RW. Primary Sarcomas of the Larynx: A Single Institutional Experience with Ten Cases. Head Neck Pathol. 2020 Sep; 14(3):707-714. PMID: 31813100.
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    6. Yang X, Rodriguez ML, Leonard A, Sun L, Fischer KA, Wang Y, Ritterhoff J, Zhao L, Kolwicz SC, Pabon L, Reinecke H, Sniadecki NJ, Tian R, Ruohola-Baker H, Xu H, Murry CE. Fatty Acids Enhance the Maturation of Cardiomyocytes Derived from Human Pluripotent Stem Cells. Stem Cell Reports. 2019 Oct 08; 13(4):657-668. PMID: 31564645.
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    7. Zhao L, Sun L, Lu Y, Li F, Xu H. A small-molecule LF3 abrogates ß-catenin/TCF4-mediated suppression of NaV1.5 expression in HL-1 cardiomyocytes. J Mol Cell Cardiol. 2019 Oct; 135:90-96. PMID: 31419437.
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    8. Huo R, Hu C, Zhao L, Sun L, Wang N, Lu Y, Ye B, Deb A, Li F, Xu H. Enhancement of ß-catenin/T-cell factor 4 signaling causes susceptibility to cardiac arrhythmia by suppressing NaV1.5 expression in mice. Heart Rhythm. 2019 Nov; 16(11):1720-1728. PMID: 31125668.
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    9. Seki A, Anklesaria Z, Saggar R, Dodson MW, Schwab K, Liu MC, Charan Ashana D, Miller WD, Vangala S, DerHovanessian A, Channick R, Shaikh F, Belperio JA, Weigt SS, Lynch JP, Ross DJ, Sullivan L, Khanna D, Shapiro SS, Sager J, Gargani L, Stanziola A, Bossone E, Schraufnagel DE, Fishbein G, Xu H, Fishbein MC, Wallace WD, Saggar R. Capillary Proliferation in Systemic-Sclerosis-Related Pulmonary Fibrosis: Association with Pulmonary Hypertension. ACR Open Rheumatol. 2019 Mar; 1(1):26-36. PMID: 31777777.
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    10. Ye B, Li L, Xu H, Chen Y, Li F. Opposing roles of TCF7/LEF1 and TCF7L2 in cyclin D2 and Bmp4 expression and cardiomyocyte cell cycle control during late heart development. Lab Invest. 2019 Jun; 99(6):807-818. PMID: 30778164.
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    11. Arcega RS, Woo JS, Xu H. Performing and Cutting Frozen Sections. Methods Mol Biol. 2019; 1897:279-288. PMID: 30539452.
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    12. Nasrullah A, Fadl S, Ahuja J, Xu H, Kicska G. Radiographic Signs and Patterns in Interstitial Lung Disease. Semin Roentgenol. 2019 Jan; 54(1):66-72. PMID: 30685001.
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    13. Guo LC, Zhu WD, Ma XY, Ni H, Zhong EJ, Shao YW, Yu J, Gu DM, Ji SD, Xu HD, Ji C, Yang JM, Zhang Y. Mutations of genes including DNMT3A detected by next-generation sequencing in thyroid cancer. Cancer Biol Ther. 2019; 20(3):240-246. PMID: 30252567.
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    14. Naeini YB, Arcega R, Hirschowitz S, Rao N, Xu H. Post-irradiation pericardial malignant mesothelioma with deletion of p16: a case report. Cancer Biol Med. 2018 Feb; 15(1):97-102. PMID: 29545973.
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    15. Fan X, Lin L, Wang J, Wang Y, Feng A, Nie L, Wu H, Meng F, Xu H. Genome profile in a extremely rare case of pulmonary sclerosing pneumocytoma presenting with diffusely-scattered nodules in the right lung. Cancer Biol Ther. 2018 Jan 02; 19(1):13-19. PMID: 29236566.
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    16. Hou N, Wen Y, Yuan X, Xu H, Wang X, Li F, Ye B. Activation of Yap1/Taz signaling in ischemic heart disease and dilated cardiomyopathy. Exp Mol Pathol. 2017 Dec; 103(3):267-275. PMID: 29154888.
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    17. Woo JS, Reddy OL, Koo M, Xiong Y, Li F, Xu H. Application of Immunohistochemistry in the Diagnosis of Pulmonary and Pleural Neoplasms. Arch Pathol Lab Med. 2017 Sep; 141(9):1195-1213. PMID: 28644685.
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    18. Zhu A, Wei X, Zhang Y, You T, Yao S, Yuan S, Xu H, Li F, Mao W. Propofol Provides Cardiac Protection by Suppressing the Proteasome Degradation of Caveolin-3 in Ischemic/Reperfused Rat Hearts. J Cardiovasc Pharmacol. 2017 Mar; 69(3):170-177. PMID: 28009721.
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    19. Hou N, Ye B, Li X, Margulies KB, Xu H, Wang X, Li F. Transcription Factor 7-like 2 Mediates Canonical Wnt/ß-Catenin Signaling and c-Myc Upregulation in Heart Failure. Circ Heart Fail. 2016 Jun; 9(6). PMID: 27301468.
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    20. Wang N, Huo R, Cai B, Lu Y, Ye B, Li X, Li F, Xu H. Activation of Wnt/ß-catenin signaling by hydrogen peroxide transcriptionally inhibits NaV1.5 expression. Free Radic Biol Med. 2016 Jul; 96:34-44. PMID: 27068063.
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    21. Ye B, Hou N, Xiao L, Xu Y, Xu H, Li F. Dynamic monitoring of oxidative DNA double-strand break and repair in cardiomyocytes. Cardiovasc Pathol. 2016; 25(2):93-100. PMID: 26764141.
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    22. Ye B, Hou N, Xiao L, Xu Y, Boyer J, Xu H, Li F. APC controls asymmetric Wnt/ß-catenin signaling and cardiomyocyte proliferation gradient in the heart. J Mol Cell Cardiol. 2015 Dec; 89(Pt B):287-96. PMID: 26493106.
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    23. Ye B, Cappel J, Findeis-Hosey J, McMahon L, Yang Q, Xiao GQ, Xu H, Li F. hASH1 is a specific immunohistochemical marker for lung neuroendocrine tumors. Hum Pathol. 2016 Feb; 48:142-7. PMID: 26596584.
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    24. Fishbein GA, Grimes BS, Xian RR, Lee JM, Barjaktarevic I, Xu H. Primary salivary duct carcinoma of the lung, mucin-rich variant. Hum Pathol. 2016 Jan; 47(1):150-6. PMID: 26527521.
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    25. Lewis JS, Tarabishy Y, Luo J, Mani H, Bishop JA, Leon ME, Prasad ML, Xu H, Di Palma S. Inter- and intra-observer variability in the classification of extracapsular extension in p16 positive oropharyngeal squamous cell carcinoma nodal metastases. Oral Oncol. 2015 Nov; 51(11):985-990. PMID: 26293844.
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    26. You T, Mao W, Cai B, Li F, Xu H. Two novel Brugada syndrome-associated mutations increase KV4.3 membrane expression and function. Int J Mol Med. 2015 Jul; 36(1):309-15. PMID: 26016905.
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    27. Arcega R, Yong WH, Xu H. Malignant melanoma mimicking giant cell variant of glioblastoma multiforme: a case report and review of literature. Int J Clin Exp Pathol. 2015; 8(5):5929-33. PMID: 26191321.
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    28. Guo J, Yao H, Lin X, Xu H, Dean D, Zhu Z, Liu G, Sime P. IL-13 induces YY1 through the AKT pathway in lung fibroblasts. PLoS One. 2015; 10(3):e0119039. PMID: 25775215.
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    29. Ji C, Zhang B, Zhu W, Ling C, Hu X, Chen Y, Huang J, Guo L, Xu H. Evaluation of ¹8F-fluorodeoxyglucose uptake in enlarged mediastinal lymph nodes in patients with lung cancer. Int J Clin Exp Pathol. 2014; 7(11):8227-34. PMID: 25550877.
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    30. Wu Y, Xu H, Zhu H, Zhu X, Liang J, Zeng Y, Zhang S, Yi X. [Clinical and histopathological features of colorectal sessile serrated adenoma/polyp and its differential diagnosis]. Zhonghua Bing Li Xue Za Zhi. 2014 Sep; 43(9):588-92. PMID: 25471498.
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    31. Chen H, Fang X, Zhu H, Li S, He J, Gu P, Fan D, Han F, Zeng Y, Yu X, Luo B, Xu H, Yi X. Gene expression profile analysis for different idiopathic interstitial pneumonias subtypes. Exp Lung Res. 2014 Oct; 40(8):367-79. PMID: 25058599.
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    32. Cai B, Wang N, Mao W, You T, Lu Y, Li X, Ye B, Li F, Xu H. Deletion of FoxO1 leads to shortening of QRS by increasing Na(+) channel activity through enhanced expression of both cardiac NaV1.5 and ß3 subunit. J Mol Cell Cardiol. 2014 Sep; 74:297-306. PMID: 24956219.
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    33. Harpaz N, Taboada S, Ko HM, Yu J, Yang Q, Xu H, Cao W. Expression of MACC1 and MET in inflammatory bowel disease-associated colonic neoplasia. Inflamm Bowel Dis. 2014 Apr; 20(4):703-11. PMID: 24518605.
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    34. Chen Y, Nowak I, Huang J, Keng PC, Sun H, Xu H, Wei G, Lee SO. Erk/MAP kinase signaling pathway and neuroendocrine differentiation of non-small-cell lung cancer. J Thorac Oncol. 2014 Jan; 9(1):50-8. PMID: 24346093.
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    35. Choy B, Findeis-Hosey JJ, Li F, McMahon LA, Yang Q, Xu H. High frequency of coexpression of maspin with p63 and p53 in squamous cell carcinoma but not in adenocarcinoma of the lung. Int J Clin Exp Pathol. 2013; 6(11):2542-7. PMID: 24228118.
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    36. Chan OT, Chiles L, Levy M, Zhai J, Yerian LM, Xu H, Xiao SY, Soffer EE, Conklin JL, Dhall D, Kahn ME, Balzer BL, Amin MB, Wang HL. Smoothelin expression in the gastrointestinal tract: implication in colonic inertia. Appl Immunohistochem Mol Morphol. 2013 Oct; 21(5):452-9. PMID: 23060305.
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    37. Desouki MM, Lioyd J, Xu H, Cao D, Barner R, Zhao C. CDX2 may be a useful marker to distinguish primary ovarian carcinoid from gastrointestinal metastatic carcinoids to the ovary. Hum Pathol. 2013 Nov; 44(11):2536-41. PMID: 24029704.
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    38. Fan X, Liu B, Xu H, Yu B, Shi S, Zhang J, Wang X, Wang J, Lu Z, Ma H, Zhou X. Immunostaining with EGFR mutation-specific antibodies: a reliable screening method for lung adenocarcinomas harboring EGFR mutation in biopsy and resection samples. Hum Pathol. 2013 Aug; 44(8):1499-507. PMID: 23465272.
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    39. Xiong Y, Bai Y, Leong N, Laughlin TS, Rothberg PG, Xu H, Nong L, Zhao J, Dong Y, Li T. Immunohistochemical detection of mutations in the epidermal growth factor receptor gene in lung adenocarcinomas using mutation-specific antibodies. Diagn Pathol. 2013 Feb 18; 8:27. PMID: 23419122.
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    40. Le NT, Heo KS, Takei Y, Lee H, Woo CH, Chang E, McClain C, Hurley C, Wang X, Li F, Xu H, Morrell C, Sullivan MA, Cohen MS, Serafimova IM, Taunton J, Fujiwara K, Abe J. A crucial role for p90RSK-mediated reduction of ERK5 transcriptional activity in endothelial dysfunction and atherosclerosis. Circulation. 2013 Jan 29; 127(4):486-99. PMID: 23243209.
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    41. Denby KS, Briones AJ, Bourne PA, Spaulding BO, Lu D, Fischer-Colbrie R, Qu Z, Wang HL, Xu H. IMP3, NESP55, TTF-1 and CDX2 serve as an immunohistochemical panel in the distinction among small-cell carcinoma, gastrointestinal carcinoid, and pancreatic endocrine tumor metastasized to the liver. Appl Immunohistochem Mol Morphol. 2012 Dec; 20(6):573-9. PMID: 22495359.
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    42. Schmidt MT, Himmelfarb EA, Shafi H, Lin F, Xu H, Wang HL. Use of IMP3, S100P, and pVHL immunopanel to aid in the interpretation of bile duct biopsies with atypical histology or suspicious for malignancy. Appl Immunohistochem Mol Morphol. 2012 Oct; 20(5):478-87. PMID: 22495381.
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    43. Klunder A, Subik K, Ye B, Xu H, Li F. Intimal sarcoma of the abdominal aorta presenting as a retroperitoneal mass. Pathology. 2012 Aug; 44(5):485-7. PMID: 22744172.
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    44. Thunnissen E, Beasley MB, Borczuk AC, Brambilla E, Chirieac LR, Dacic S, Flieder D, Gazdar A, Geisinger K, Hasleton P, Ishikawa Y, Kerr KM, Lantejoul S, Matsuno Y, Minami Y, Moreira AL, Motoi N, Nicholson AG, Noguchi M, Nonaka D, Pelosi G, Petersen I, Rekhtman N, Roggli V, Travis WD, Tsao MS, Wistuba I, Xu H, Yatabe Y, Zakowski M, Witte B, Kuik DJ. Reproducibility of histopathological subtypes and invasion in pulmonary adenocarcinoma. An international interobserver study. Mod Pathol. 2012 Dec; 25(12):1574-83. PMID: 22814311.
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    45. Lim JH, Jono H, Komatsu K, Woo CH, Lee J, Miyata M, Matsuno T, Xu X, Huang Y, Zhang W, Park SH, Kim YI, Choi YD, Shen H, Heo KS, Xu H, Bourne P, Koga T, Xu H, Yan C, Wang B, Chen LF, Feng XH, Li JD. CYLD negatively regulates transforming growth factor-ß-signalling via deubiquitinating Akt. Nat Commun. 2012 Apr 10; 3:771. PMID: 22491319.
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    46. Ye B, Ge Y, Perens G, Hong L, Xu H, Fishbein MC, Li F. Canonical Wnt/ß-catenin signaling in epicardial fibrosis of failed pediatric heart allografts with diastolic dysfunction. Cardiovasc Pathol. 2013; 22(1):54-7. PMID: 22475572.
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    47. Mao W, You T, Ye B, Li X, Dong HH, Hill JA, Li F, Xu H. Reactive oxygen species suppress cardiac NaV1.5 expression through Foxo1. PLoS One. 2012; 7(2):e32738. PMID: 22400069.
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    48. Li F, Ye B, Hong L, Xu H, Fishbein MC. Epigenetic modifications of histone h4 in lung neuroendocrine tumors. Appl Immunohistochem Mol Morphol. 2011 Oct; 19(5):389-94. PMID: 21415707.
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    49. Levy M, Trivedi A, Zhang J, Miles L, Mattis AN, Kim GE, Lassman C, Anders RA, Misdraji J, Yerian LM, Xu H, Dhall D, Wang HL. Expression of glypican-3 in undifferentiated embryonal sarcoma and mesenchymal hamartoma of the liver. Hum Pathol. 2012 May; 43(5):695-701. PMID: 21937079.
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    50. Mentrikoski MJ, Zhao C, Zhang J, Wang HL, McMahon LA, Yang Q, Li F, Xu H. Metastatic endometrial stromal sarcoma of the lung: importance of immunohistochemical staining, clinical history and imaging studies. Biotech Histochem. 2012 Jan; 87(1):35-9. PMID: 21838613.
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    51. Ye J, Hameed O, Findeis-Hosey JJ, Fan L, Li F, McMahon LA, Yang Q, Wang HL, Xu H. Diagnostic utility of PAX8, TTF-1 and napsin A for discriminating metastatic carcinoma from primary adenocarcinoma of the lung. Biotech Histochem. 2012 Jan; 87(1):30-4. PMID: 21838611.
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    52. Findeis-Hosey JJ, Xu H. Insulin-like growth factor II-messenger RNA-binding protein-3 and lung cancer. Biotech Histochem. 2012 Jan; 87(1):24-9. PMID: 21838610.
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    53. Ye J, Findeis-Hosey JJ, Yang Q, McMahon LA, Yao JL, Li F, Xu H. Combination of napsin A and TTF-1 immunohistochemistry helps in differentiating primary lung adenocarcinoma from metastatic carcinoma in the lung. Appl Immunohistochem Mol Morphol. 2011 Jul; 19(4):313-7. PMID: 21464700.
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    54. Findeis-Hosey JJ, Huang J, Li F, Yang Q, McMahon LA, Xu H. High-grade neuroendocrine carcinomas of the lung highly express enhancer of zeste homolog 2, but carcinoids do not. Hum Pathol. 2011 Jun; 42(6):867-72. PMID: 21292308.
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    55. Lin X, Sime PJ, Xu H, Williams MA, LaRussa L, Georas SN, Guo J. Yin yang 1 is a novel regulator of pulmonary fibrosis. Am J Respir Crit Care Med. 2011 Jun 15; 183(12):1689-97. PMID: 21169469.
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    56. Li F, Wang X, Xu H, Roggli VL. Small neuroendocrine lesions in intrathoracic lymph nodes of patients with primary lung adenocarcinoma: real metastasis? Am J Surg Pathol. 2010 Nov; 34(11):1701-7. PMID: 20871390.
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    57. Findeis-Hosey JJ, Xu H. The use of insulin like-growth factor II messenger RNA binding protein-3 in diagnostic pathology. Hum Pathol. 2011 Mar; 42(3):303-14. PMID: 20970161.
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    58. Hu Y, Yang Q, McMahon LA, Wang HL, Xu H. Value of D2-40 in the differential diagnosis of pleural neoplasms with emphasis on its positivity in solitary fibrous tumor. Appl Immunohistochem Mol Morphol. 2010 Oct; 18(5):411-3. PMID: 20436345.
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    59. Manganaris C, Wittlin S, Xu H, Gurell M, Sime P, Kottmann RM. Metastatic papillary thyroid carcinoma and severe airflow obstruction. Chest. 2010 Sep; 138(3):738-42. PMID: 20822998.
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    60. Johnson MD, Vito F, Xu H. MUC16 expression and risk of adenocarcinoma metastases to peritoneum, pleura, leptomeninges, and brain. Appl Immunohistochem Mol Morphol. 2010 May; 18(3):250-3. PMID: 20090516.
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    61. Levy M, Lin F, Xu H, Dhall D, Spaulding BO, Wang HL. S100P, von Hippel-Lindau gene product, and IMP3 serve as a useful immunohistochemical panel in the diagnosis of adenocarcinoma on endoscopic bile duct biopsy. Hum Pathol. 2010 Sep; 41(9):1210-9. PMID: 20382408.
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    62. Findeis-Hosey JJ, Yang Q, Spaulding BO, Wang HL, Xu H. IMP3 expression is correlated with histologic grade of lung adenocarcinoma. Hum Pathol. 2010 Apr; 41(4):477-84. PMID: 20004948.
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    63. Hu Y, Mahar TJ, Hicks DG, Raymond D, Jones C, Wandtke JC, Powers JM, Xu H. Malignant solitary fibrous tumor: report of 3 cases with unusual features. Appl Immunohistochem Mol Morphol. 2009 Oct; 17(5):451-7. PMID: 19349855.
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    64. Yu L, Xu H, Wasco MJ, Bourne PA, Ma L. IMP-3 expression in melanocytic lesions. J Cutan Pathol. 2010 Mar; 37(3):316-22. PMID: 19788446.
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    65. Miller CL, Oikawa M, Cai Y, Wojtovich AP, Nagel DJ, Xu X, Xu H, Florio V, Rybalkin SD, Beavo JA, Chen YF, Li JD, Blaxall BC, Abe J, Yan C. Role of Ca2+/calmodulin-stimulated cyclic nucleotide phosphodiesterase 1 in mediating cardiomyocyte hypertrophy. Circ Res. 2009 Nov 06; 105(10):956-64. PMID: 19797176.
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    66. Mentrikoski MJ, Ma L, Pryor JG, McMahon LA, Yang Q, Spaulding BO, Scott GA, Wang HL, Xu H. Diagnostic utility of IMP3 in segregating metastatic melanoma from benign nevi in lymph nodes. Mod Pathol. 2009 Dec; 22(12):1582-7. PMID: 19734845.
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    67. Köbel M, Xu H, Bourne PA, Spaulding BO, Shih IeM, Mao TL, Soslow RA, Ewanowich CA, Kalloger SE, Mehl E, Lee CH, Huntsman D, Gilks CB. IGF2BP3 (IMP3) expression is a marker of unfavorable prognosis in ovarian carcinoma of clear cell subtype. Mod Pathol. 2009 Mar; 22(3):469-75. PMID: 19136932.
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    68. Miyamoto H, Jones CE, Raymond DP, Wandtke JC, Strang JG, Bourne PA, Bonfiglio TA, Xu H. Pulmonary metastases from uterine neoplasms after long tumour-free interval: four cases and review of the literature. Pathology. 2009; 41(3):234-41. PMID: 19291535.
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    69. Fallone E, Bourne PA, Watson TJ, Ghossein RA, Travis WD, Xu H. Ectopic (mediastinal) parathyroid adenoma with prominent lymphocytic infiltration. Appl Immunohistochem Mol Morphol. 2009 Jan; 17(1):82-4. PMID: 19115487.
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    70. Pryor JG, Simon RA, Bourne PA, Spaulding BO, Scott GA, Xu H. Merkel cell carcinoma expresses K homology domain-containing protein overexpressed in cancer similar to other high-grade neuroendocrine carcinomas. Hum Pathol. 2009 Feb; 40(2):238-43. PMID: 18835627.
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    71. Simon RA, di Sant'Agnese PA, Huang LS, Xu H, Yao JL, Yang Q, Liang S, Liu J, Yu R, Cheng L, Oh WK, Palapattu GS, Wei J, Huang J. CD44 expression is a feature of prostatic small cell carcinoma and distinguishes it from its mimickers. Hum Pathol. 2009 Feb; 40(2):252-8. PMID: 18835619.
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    72. Lester T, Xu H. Malignant pleural mesothelioma with osseous metastases and pathologic fracture of femoral neck. Appl Immunohistochem Mol Morphol. 2008 Oct; 16(5):507-9. PMID: 18580495.
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    73. Gurell MN, Kottmann RM, Xu H, Sime PJ. Exogenous lipoid pneumonia: an unexpected complication of substance abuse. Ann Intern Med. 2008 Sep 02; 149(5):364-5. PMID: 18765715.
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    74. Xu H. IMP3: a diagnostic and prognostic biomarker in malignant melanoma. Expert Rev Mol Diagn. 2008 Sep; 8(5):557-8. PMID: 18785801.
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    75. Lu Z, Abe J, Taunton J, Lu Y, Shishido T, McClain C, Yan C, Xu SP, Spangenberg TM, Xu H. Reactive oxygen species-induced activation of p90 ribosomal S6 kinase prolongs cardiac repolarization through inhibiting outward K+ channel activity. Circ Res. 2008 Aug 01; 103(3):269-78. PMID: 18599872.
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    76. Li L, Xu H, Spaulding BO, Cheng L, Simon R, Yao JL, di Sant'Agnese PA, Bourne PA, Huang J. Expression of RNA-binding protein IMP3 (KOC) in benign urothelium and urothelial tumors. Hum Pathol. 2008 Aug; 39(8):1205-11. PMID: 18547613.
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    77. Wagner D, Bourne PA, Yang Q, Goldman BI, Lewis JS, Xu H. Unusual features of malignant pleural mesothelioma metastatic to the mediastinal lymph nodes. Appl Immunohistochem Mol Morphol. 2008 May; 16(3):301-7. PMID: 18301236.
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    78. Hanley KZ, Facik MS, Bourne PA, Yang Q, Spaulding BO, Bonfiglio TA, Xu H. Utility of anti-L523S antibody in the diagnosis of benign and malignant serous effusions. Cancer. 2008 Feb 25; 114(1):49-56. PMID: 18098206.
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    79. Pryor JG, Bourne PA, Yang Q, Spaulding BO, Scott GA, Xu H. IMP-3 is a novel progression marker in malignant melanoma. Mod Pathol. 2008 Apr; 21(4):431-7. PMID: 18204432.
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    80. LaPoint RJ, Bourne PA, Wang HL, Xu H. Coexpression of c-kit and bcl-2 in small cell carcinoma and large cell neuroendocrine carcinoma of the lung. Appl Immunohistochem Mol Morphol. 2007 Dec; 15(4):401-6. PMID: 18091382.
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    81. Lim JH, Jono H, Koga T, Woo CH, Ishinaga H, Bourne P, Xu H, Ha UH, Xu H, Li JD. Tumor suppressor CYLD acts as a negative regulator for non-typeable Haemophilus influenza-induced inflammation in the middle ear and lung of mice. PLoS One. 2007 Oct 10; 2(10):e1032. PMID: 17925880.
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    82. Lim JH, Stirling B, Derry J, Koga T, Jono H, Woo CH, Xu H, Bourne P, Ha UH, Ishinaga H, Xu H, Andalibi A, Feng XH, Zhu H, Huang Y, Zhang W, Weng X, Yan C, Yin Z, Briles DE, Davis RJ, Flavell RA, Li JD. Tumor suppressor CYLD regulates acute lung injury in lethal Streptococcus pneumoniae infections. Immunity. 2007 Aug; 27(2):349-60. PMID: 17723219.
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    83. Miyamoto H, Molena DA, Schoeniger LO. Solitary fibrous tumor of the pancreas: a case report. Int J Surg Pathol. 2007 Jul; 15(3):311-4. PMID: 17652547.
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    84. Simon R, Bourne PA, Yang Q, Spaulding BO, di Sant'Agnese PA, Wang HL, Xu H. Extrapulmonary small cell carcinomas express K homology domain containing protein overexpressed in cancer, but carcinoid tumors do not. Hum Pathol. 2007 Aug; 38(8):1178-83. PMID: 17521698.
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    85. Xu H, Bourne PA, Spaulding BO, Wang HL. High-grade neuroendocrine carcinomas of the lung express K homology domain containing protein overexpressed in cancer but carcinoid tumors do not. Hum Pathol. 2007 Apr; 38(4):555-63. PMID: 17316760.
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    86. Yan C, Ding B, Shishido T, Woo CH, Itoh S, Jeon KI, Liu W, Xu H, McClain C, Molina CA, Blaxall BC, Abe J. Activation of extracellular signal-regulated kinase 5 reduces cardiac apoptosis and dysfunction via inhibition of a phosphodiesterase 3A/inducible cAMP early repressor feedback loop. Circ Res. 2007 Mar 02; 100(4):510-9. PMID: 17272811.
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    87. Ishinaga H, Jono H, Lim JH, Kweon SM, Xu H, Ha UH, Xu H, Koga T, Yan C, Feng XH, Chen LF, Li JD. TGF-beta induces p65 acetylation to enhance bacteria-induced NF-kappaB activation. EMBO J. 2007 Feb 21; 26(4):1150-62. PMID: 17268554.
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    88. Hameed O, Xu H, Saddeghi S, Maluf H. Hepatoid carcinoma of the pancreas: a case report and literature review of a heterogeneous group of tumors. Am J Surg Pathol. 2007 Jan; 31(1):146-52. PMID: 17197931.
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    89. Wagner D, Joseph J, Huang J, Xu H. Malakoplakia of the prostate on needle core biopsy: a case report and review of the literature. Int J Surg Pathol. 2007 Jan; 15(1):86-9. PMID: 17172507.
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    90. Shah AP, Xu H, Sime PJ, Trawick DR. Severe airflow obstruction and eosinophilic lung disease after Stevens-Johnson syndrome. Eur Respir J. 2006 Dec; 28(6):1276-9. PMID: 17138682.
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    91. Bhagwat SP, Gigliotti F, Xu H, Wright TW. Contribution of T cell subsets to the pathophysiology of Pneumocystis-related immunorestitution disease. Am J Physiol Lung Cell Mol Physiol. 2006 Dec; 291(6):L1256-66. PMID: 16891394.
      Citations:    
    92. Guo W, Jung WE, Marionneau C, Aimond F, Xu H, Yamada KA, Schwarz TL, Demolombe S, Nerbonne JM. Targeted deletion of Kv4.2 eliminates I(to,f) and results in electrical and molecular remodeling, with no evidence of ventricular hypertrophy or myocardial dysfunction. Circ Res. 2005 Dec 09; 97(12):1342-50. PMID: 16293790.
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    93. Ding B, Abe J, Wei H, Xu H, Che W, Aizawa T, Liu W, Molina CA, Sadoshima J, Blaxall BC, Berk BC, Yan C. A positive feedback loop of phosphodiesterase 3 (PDE3) and inducible cAMP early repressor (ICER) leads to cardiomyocyte apoptosis. Proc Natl Acad Sci U S A. 2005 Oct 11; 102(41):14771-6. PMID: 16186489.
      Citations:    
    94. Chiu HC, Kovacs A, Blanton RM, Han X, Courtois M, Weinheimer CJ, Yamada KA, Brunet S, Xu H, Nerbonne JM, Welch MJ, Fettig NM, Sharp TL, Sambandam N, Olson KM, Ory DS, Schaffer JE. Transgenic expression of fatty acid transport protein 1 in the heart causes lipotoxic cardiomyopathy. Circ Res. 2005 Feb 04; 96(2):225-33. PMID: 15618539.
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    95. Xu H, Lu DW, El-Mofty SK, Wang HL. Metachronous squamous cell carcinomas evolving from independent oropharyngeal and pulmonary squamous papillomas: association with human papillomavirus 11 and lack of aberrant p53, Rb, and p16 protein expression. Hum Pathol. 2004 Nov; 35(11):1419-22. PMID: 15668901.
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    96. Okamoto RJ, Xu H, Kouchoukos NT, Moon MR, Sundt TM. The influence of mechanical properties on wall stress and distensibility of the dilated ascending aorta. J Thorac Cardiovasc Surg. 2003 Sep; 126(3):842-50. PMID: 14502164.
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    97. Goldstein JA, Beardslee MA, Xu H, Sundt TM, Lasala JM. Infective endocarditis resulting from CardioSEAL closure of a patent foramen ovale. Catheter Cardiovasc Interv. 2002 Feb; 55(2):217-20; discussion 221. PMID: 11835650.
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    98. Sundt TM, Moon MR, Xu H. Reoperation for dilatation of the pulmonary autograft after the Ross procedure. J Thorac Cardiovasc Surg. 2001 Dec; 122(6):1249-52. PMID: 11726908.
      Citations:    
    99. Li H, Guo W, Xu H, Hood R, Benedict AT, Nerbonne JM. Functional expression of a GFP-tagged Kv1.5 alpha-subunit in mouse ventricle. Am J Physiol Heart Circ Physiol. 2001 Nov; 281(5):H1955-67. PMID: 11668056.
      Citations:    
    100. Guo W, Xu H, London B, Nerbonne JM. Molecular basis of transient outward K+ current diversity in mouse ventricular myocytes. J Physiol. 1999 Dec 15; 521 Pt 3(Pt 3):587-99. PMID: 10601491.
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    101. Xu H, Barry DM, Li H, Brunet S, Guo W, Nerbonne JM. Attenuation of the slow component of delayed rectification, action potential prolongation, and triggered activity in mice expressing a dominant-negative Kv2 alpha subunit. Circ Res. 1999 Oct 01; 85(7):623-33. PMID: 10506487.
      Citations:    
    102. Xu H, Li H, Nerbonne JM. Elimination of the transient outward current and action potential prolongation in mouse atrial myocytes expressing a dominant negative Kv4 alpha subunit. J Physiol. 1999 Aug 15; 519 Pt 1(Pt 1):11-21. PMID: 10432335.
      Citations:    
    103. Xu H, Guo W, Nerbonne JM. Four kinetically distinct depolarization-activated K+ currents in adult mouse ventricular myocytes. J Gen Physiol. 1999 May; 113(5):661-78. PMID: 10228181.
      Citations:    
    104. Barry DM, Xu H, Schuessler RB, Nerbonne JM. Functional knockout of the transient outward current, long-QT syndrome, and cardiac remodeling in mice expressing a dominant-negative Kv4 alpha subunit. Circ Res. 1998 Sep 07; 83(5):560-7. PMID: 9734479.
      Citations:    
    105. Xu H, Dixon JE, Barry DM, Trimmer JS, Merlie JP, McKinnon D, Nerbonne JM. Developmental analysis reveals mismatches in the expression of K+ channel alpha subunits and voltage-gated K+ channel currents in rat ventricular myocytes. J Gen Physiol. 1996 Nov; 108(5):405-19. PMID: 8923266.
      Citations:    
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