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Endogenous signals released from necrotic cells augment inflammatory responses to bacterial endotoxin.
Improved adaptive randomization strategies for a seamless Phase I/II dose-finding design.
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Improved adaptive randomization strategies for a seamless Phase I/II dose-finding design.
Yan D, Wages NA, Dressler EV. Improved adaptive randomization strategies for a seamless Phase I/II dose-finding design. J Biopharm Stat. 2019; 29(2):333-347.
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PubMed
subject areas
Algorithms
Antineoplastic Agents
Clinical Trials, Phase I as Topic
Clinical Trials, Phase II as Topic
Computer Simulation
Dose-Response Relationship, Drug
Humans
Maximum Tolerated Dose
Models, Statistical
Neoplasms
Randomized Controlled Trials as Topic
Sample Size
Treatment Outcome
authors with profiles
Emily V. Dressler PhD