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Connection

Donald Mcclain to Glucose

This is a "connection" page, showing publications Donald Mcclain has written about Glucose.
Connection Strength

3.988
  1. Nam H, Jones D, Cooksey RC, Gao Y, Sink S, Cox J, McClain DA. Synergistic Inhibitory Effects of Hypoxia and Iron Deficiency on Hepatic Glucose Response in Mouse Liver. Diabetes. 2016 06; 65(6):1521-33.
    View in: PubMed
    Score: 0.513
  2. Simcox JA, Mitchell TC, Gao Y, Just SF, Cooksey R, Cox J, Ajioka R, Jones D, Lee SH, King D, Huang J, McClain DA. Dietary iron controls circadian hepatic glucose metabolism through heme synthesis. Diabetes. 2015 Apr; 64(4):1108-19.
    View in: PubMed
    Score: 0.465
  3. Huang J, Simcox J, Mitchell TC, Jones D, Cox J, Luo B, Cooksey RC, Boros LG, McClain DA. Iron regulates glucose homeostasis in liver and muscle via AMP-activated protein kinase in mice. FASEB J. 2013 Jul; 27(7):2845-54.
    View in: PubMed
    Score: 0.417
  4. Cooksey RC, Jones D, Gabrielsen S, Huang J, Simcox JA, Luo B, Soesanto Y, Rienhoff H, Abel ED, McClain DA. Dietary iron restriction or iron chelation protects from diabetes and loss of beta-cell function in the obese (ob/ob lep-/-) mouse. Am J Physiol Endocrinol Metab. 2010 Jun; 298(6):E1236-43.
    View in: PubMed
    Score: 0.339
  5. Taylor RP, Geisler TS, Chambers JH, McClain DA. Up-regulation of O-GlcNAc transferase with glucose deprivation in HepG2 cells is mediated by decreased hexosamine pathway flux. J Biol Chem. 2009 Feb 06; 284(6):3425-32.
    View in: PubMed
    Score: 0.310
  6. Taylor RP, Parker GJ, Hazel MW, Soesanto Y, Fuller W, Yazzie MJ, McClain DA. Glucose deprivation stimulates O-GlcNAc modification of proteins through up-regulation of O-linked N-acetylglucosaminyltransferase. J Biol Chem. 2008 Mar 07; 283(10):6050-7.
    View in: PubMed
    Score: 0.291
  7. Cooksey RC, Pusuluri S, Hazel M, McClain DA. Hexosamines regulate sensitivity of glucose-stimulated insulin secretion in beta-cells. Am J Physiol Endocrinol Metab. 2006 Feb; 290(2):E334-40.
    View in: PubMed
    Score: 0.248
  8. McClain DA, Hazel M, Parker G, Cooksey RC. Adipocytes with increased hexosamine flux exhibit insulin resistance, increased glucose uptake, and increased synthesis and storage of lipid. Am J Physiol Endocrinol Metab. 2005 May; 288(5):E973-9.
    View in: PubMed
    Score: 0.236
  9. McClain DA, Sharma NK, Jain S, Harrison A, Salaye LN, Comeau ME, Langefeld CD, Lorenzo FR, Das SK. Adipose Tissue Transferrin and Insulin Resistance. J Clin Endocrinol Metab. 2018 11 01; 103(11):4197-4208.
    View in: PubMed
    Score: 0.154
  10. Shannon C, Merovci A, Xiong J, Tripathy D, Lorenzo F, McClain D, Abdul-Ghani M, Norton L, DeFronzo RA. Effect of Chronic Hyperglycemia on Glucose Metabolism in Subjects With Normal Glucose Tolerance. Diabetes. 2018 12; 67(12):2507-2517.
    View in: PubMed
    Score: 0.153
  11. Fernández-Real JM, McClain D, Manco M. Mechanisms Linking Glucose Homeostasis and Iron Metabolism Toward the Onset and Progression of Type 2 Diabetes. Diabetes Care. 2015 Nov; 38(11):2169-76.
    View in: PubMed
    Score: 0.125
  12. Simcox JA, McClain DA. Iron and diabetes risk. Cell Metab. 2013 Mar 05; 17(3):329-41.
    View in: PubMed
    Score: 0.104
  13. Huang J, Jones D, Luo B, Sanderson M, Soto J, Abel ED, Cooksey RC, McClain DA. Iron overload and diabetes risk: a shift from glucose to Fatty Acid oxidation and increased hepatic glucose production in a mouse model of hereditary hemochromatosis. Diabetes. 2011 Jan; 60(1):80-7.
    View in: PubMed
    Score: 0.088
  14. Cooksey RC, McClain DA. Increased hexosamine pathway flux and high fat feeding are not additive in inducing insulin resistance: evidence for a shared pathway. Amino Acids. 2011 Mar; 40(3):841-6.
    View in: PubMed
    Score: 0.087
  15. Jouihan HA, Cobine PA, Cooksey RC, Hoagland EA, Boudina S, Abel ED, Winge DR, McClain DA. Iron-mediated inhibition of mitochondrial manganese uptake mediates mitochondrial dysfunction in a mouse model of hemochromatosis. Mol Med. 2008 Mar-Apr; 14(3-4):98-108.
    View in: PubMed
    Score: 0.073
  16. Luo B, Soesanto Y, McClain DA. Protein modification by O-linked GlcNAc reduces angiogenesis by inhibiting Akt activity in endothelial cells. Arterioscler Thromb Vasc Biol. 2008 Apr; 28(4):651-7.
    View in: PubMed
    Score: 0.073
  17. Huang J, Gabrielsen JS, Cooksey RC, Luo B, Boros LG, Jones DL, Jouihan HA, Soesanto Y, Knecht L, Hazel MW, Kushner JP, McClain DA. Increased glucose disposal and AMP-dependent kinase signaling in a mouse model of hemochromatosis. J Biol Chem. 2007 Dec 28; 282(52):37501-7.
    View in: PubMed
    Score: 0.072
  18. Wende AR, Schaeffer PJ, Parker GJ, Zechner C, Han DH, Chen MM, Hancock CR, Lehman JJ, Huss JM, McClain DA, Holloszy JO, Kelly DP. A role for the transcriptional coactivator PGC-1alpha in muscle refueling. J Biol Chem. 2007 Dec 14; 282(50):36642-51.
    View in: PubMed
    Score: 0.072
  19. Hao HX, Cardon CM, Swiatek W, Cooksey RC, Smith TL, Wilde J, Boudina S, Abel ED, McClain DA, Rutter J. PAS kinase is required for normal cellular energy balance. Proc Natl Acad Sci U S A. 2007 Sep 25; 104(39):15466-71.
    View in: PubMed
    Score: 0.071
  20. Parker GJ, Lund KC, Taylor RP, McClain DA. Insulin resistance of glycogen synthase mediated by o-linked N-acetylglucosamine. J Biol Chem. 2003 Mar 21; 278(12):10022-7.
    View in: PubMed
    Score: 0.051
  21. Shakya A, Cooksey R, Cox JE, Wang V, McClain DA, Tantin D. Oct1 loss of function induces a coordinate metabolic shift that opposes tumorigenicity. Nat Cell Biol. 2009 Mar; 11(3):320-7.
    View in: PubMed
    Score: 0.020
  22. Donthi RV, Ye G, Wu C, McClain DA, Lange AJ, Epstein PN. Cardiac expression of kinase-deficient 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase inhibits glycolysis, promotes hypertrophy, impairs myocyte function, and reduces insulin sensitivity. J Biol Chem. 2004 Nov 12; 279(46):48085-90.
    View in: PubMed
    Score: 0.014
  23. Belke DD, Betuing S, Tuttle MJ, Graveleau C, Young ME, Pham M, Zhang D, Cooksey RC, McClain DA, Litwin SE, Taegtmeyer H, Severson D, Kahn CR, Abel ED. Insulin signaling coordinately regulates cardiac size, metabolism, and contractile protein isoform expression. J Clin Invest. 2002 Mar; 109(5):629-39.
    View in: PubMed
    Score: 0.012
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.