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Stephen R. Rapp PhD

TitleProfessor
InstitutionWake Forest School of Medicine
DepartmentPsychiatry & Behavioral Medicine
Address
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    Other Positions
    TitleProfessor
    InstitutionWake Forest School of Medicine
    DepartmentSocial Sciences & Health Policy (Public Health Sciences)


    Collapse Research 
    Collapse research activities and funding
    R01NR009675     (RAPP, STEPHEN R)Apr 1, 2007 - Jul 31, 2012
    NIH
    Phase III Study of Donepezil in the Irradiated Brain
    Role Description: A randomized clinical trial of cognitive enhancing medication for patients following radiation therapy for brain tumors.
    Role: Principal Investigator
    P30AG049683-01A1     (Craft)Jul 1, 2016 - Jun 30, 2021
    NIH/NIA
    Wake Forest Alzheimer's Disease Core Center
    Role Description: This grant establishes a Alzheimer's Disease Core Center (ADCC) at Wake Forest School of Medicine that will provide a comprehensive infrastructure for translational, interdisciplinary research on the pathophysiology, prevention, and treatment of AD and related disorders.
    Role: Co-Investigator
    HHSN271-2011-00004C     (Stephen R Rapp)Nov 4, 2016 - Nov 3, 2021
    NIH/NIA
    Women's Health Initiative Memory Study: WHIMS Suite of Studies
    Role Description: Surveillance of the WHIMS-ECHO cohort to investigate dementia risk, identify predictors of cognitive aging and resilience in post-menopausal women.
    Role: PI
    R01AG050657-01     (Baker)May 15, 2017 - May 4, 2021
    NIH/NIA
    Cocoa Supplement and Multivitamin Outcomes Study in the Mind
    Role Description: RCT of the effects of cocoa flavanols and multivitamins on cardiovascular events, cognitive function and impairment.
    Role: Co-Investigator
    R01 HL133684-01A1     (Baker)Sep 1, 2017 - Jun 30, 2021
    NIH/NIA
    Women's Health Initiative Sleep Hypoxia Effects on Resilience
    Role Description: Determine whether hypoxia associated with sleep-disordered breathing increases the risk of incident cancer, CVD or cognitive impairment
    Role: Co-Investigator
    AG058969     (Hughes)Mar 31, 2018 - Apr 1, 2023
    NIH/NIA
    Subclinical Vascular Contributions to Alzheimer's Disease: The Multi Ethnic Study of Atherosclerosis
    Role Description: Determine if arterial stiffness is related to evidence of AD and AD pathology-Ethnic Study of Atherosclerosis (MESA)
    Role: Co-Investogator
    AG058571     (Espeland)Apr 1, 2018 - Mar 31, 2022
    NIH/NIA
    Look AHEAD MIND
    Role Description: Examine the legacy of a successful 10-year behavioral intervention designed to induce and maintain weight loss on the cognitive health of older individuals.
    Role: Co-Investigator
    UG1CA189824-S1     (Penzein)Sep 1, 2019 - Jul 31, 2025
    NIH/NCI
    Implementing and Evaluating mHealth Pain Coping Skills Training Interventions to Improve Self-Management of Chronic Pain in Cancer Survivors
    Role Description: This is a large-scale pragmatic randomized controlled clinical trial evaluating whether our automated mobile health pain coping skills training program (PainTRAINER) can improve persistent pain and related outcomes in patients with cancer after completion of their cancer treatment (as compared to enhanced usual care).
    Role: Co-Investigator
    1U19AG065188-01     (Alexande/Hernandez/Ambrosius/Williamson)Sep 1, 2019 - Aug 31, 2026
    NIH/NIA
    Pragmatic Evaluation of Events and Benefits of Lipid-Lowering in Older Adults
    Role Description: A placebo-controlled pragmatic trial design across PCORnet and VA health systems will evaluate the benefits vs. risks of a moderate intensity statin on important health outcomes for older adults.
    Role: Co-Investigator
    U01CA81851-09-13     (Lesser)Oct 1, 2019 - Sep 30, 2025
    NIH/NCI
    Research Base Grant of Comprehensive Cancer Center
    Role Description: Provides infrastructure and core consultation to investigators who develop and conduct cancer survivorship studies in NCORP network.
    Role: Co-Investigator
    2R01AG055606-02A1     (Reboussin D)Jul 1, 2020 - Jun 30, 2024
    NIH/NIA
    SPRINT MIND 2020
    Role Description: To obtaining an additional visit with the SPRINT cohort to provide important evidence to inform clinical decision-making on the potential for treatment of hypertension to postpone cognitive decline
    Role: Co-Investigator
    HHSN268201600004C     (Shumaker)Oct 15, 2020 - Oct 14, 2027
    NIH/NHLBI
    A placebo-controlled pragmatic trial design across PCORnet and VA health systems will evaluate the benefits vs. risks of a moderate intensity statin on important health outcomes for older adults.
    Role Description: Continued follow-up of the Women Health Initiative (WHI) - Regional Center subjects.

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Besser L, Chang LC, Evenson KR, Hirsch J, Michael Y, Galvin JE, Rapp SR, Fitzpatrick AL, Heckbert SR, Kaufman JD, Hughes TM. Associations Between Neighborhood Park Access and Longitudinal Change in Cognition in Older Adults: The Multi-Ethnic Study of Atherosclerosis. J Alzheimers Dis. 2021 May 15. PMID: 34024841.
      Citations:    
    2. Handing EP, Rapp SR, Chen SH, Rejeski WJ, Wiberg M, Bandeen-Roche K, Craft S, Kitzman D, Ip EH. Heterogeneity in Association Between Cognitive Function and Gait Speed Among Older Adults: An Integrative Data Analysis Study. J Gerontol A Biol Sci Med Sci. 2021 Mar 31; 76(4):710-715. PMID: 32841312.
      Citations:    
    3. Al-Kindi SG, Brook RD, Bhatt U, Brauer M, Cushman WC, Hanson HA, Kostis J, Lash JP, Paine R, Raphael KL, Rapp S, Tamariz L, Wright JT, Rajagopalan S. The Benefits of Intensive Versus Standard Blood Pressure Treatment According to Fine Particulate Matter Air Pollution Exposure: A Post Hoc Analysis of SPRINT. Hypertension. 2021 Mar 03; 77(3):813-822. PMID: 33517683.
      Citations:    
    4. Carmichael OT, Neiberg RH, Dutton GR, Hayden KM, Horton E, Pi-Sunyer FX, Johnson KC, Rapp SR, Spira AP, Espeland MA. Long-term Change in Physiological Markers and Cognitive Performance in Type 2 Diabetes: The Look AHEAD Study. J Clin Endocrinol Metab. 2020 12 01; 105(12). PMID: 32845968.
      Citations:    
    5. Stone D, Long KR, Loprieno MA, De Silva Feelixge HS, Kenkel EJ, Liley RM, Rapp S, Roychoudhury P, Nguyen T, Stensland L, Colón-Thillet R, Klouser LM, Weber ND, Le C, Wagoner J, Goecker EA, Li AZ, Eichholz K, Corey L, Tyrrell DL, Greninger AL, Huang ML, Polyak SJ, Aubert M, Sagartz JE, Jerome KR. CRISPR-Cas9 gene editing of hepatitis B virus in chronically infected humanized mice. Mol Ther Methods Clin Dev. 2021 Mar 12; 20:258-275. PMID: 33473359.
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    6. Younan D, Wang X, Casanova R, Barnard R, Gaussoin SA, Saldana S, Petkus AJ, Beavers DP, Resnick SM, Manson JE, Serre ML, Vizuete W, Henderson VW, Sachs BC, Salinas JA, Gatz M, Espeland MA, Chui HC, Shumaker SA, Rapp SR, Chen JC. PM2.5 associated with gray matter atrophy reflecting increased Alzheimers risk in older women. Neurology. 2020 11 18. PMID: 33208540.
      Citations:    
    7. Djonlagic I, Mariani S, Fitzpatrick AL, Van Der Klei VMGTH, Johnson DA, Wood AC, Seeman T, Nguyen HT, Prerau MJ, Luchsinger JA, Dzierzewski JM, Rapp SR, Tranah GJ, Yaffe K, Burdick KE, Stone KL, Redline S, Purcell SM. Macro and micro sleep architecture and cognitive performance in older adults. Nat Hum Behav. 2021 01; 5(1):123-145. PMID: 33199858.
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    8. Rapp SR, Gaussoin SA, Sachs BC, Chelune G, Supiano MA, Lerner AJ, Wadley VG, Wilson VM, Fine LJ, Whittle JC, Auchus AP, Beddhu S, Berlowitz DR, Bress AP, Johnson KC, Krousel-Wood M, Martindale-Adams J, Miller EC, Rifkin DE, Snyder JK, Tamariz L, Wolfgram DF, Cleveland ML, Yang M, Nichols LO, Bryan RN, Reboussin DM, Williamson JD, Pajewski NM. Effects of intensive versus standard blood pressure control on domain-specific cognitive function: a substudy of the SPRINT randomised controlled trial. Lancet Neurol. 2020 11; 19(11):899-907. PMID: 33098800.
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    9. Welti LM, Beavers KM, Mampieri A, Rapp SR, Ip E, Shumaker SA, Beavers DP. Patterns of Home Environmental Modification Use and Functional Health: The Women's Health Initiative. J Gerontol A Biol Sci Med Sci. 2020 10 15; 75(11):2119-2124. PMID: 31837269.
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    10. Kurella Tamura M, Gaussoin SA, Pajewski NM, Chelune GJ, Freedman BI, Gure TR, Haley WE, Killeen AA, Oparil S, Rapp SR, Rifkin DE, Supiano M, Williamson JD, Weiner DE. Kidney Disease, Intensive Hypertension Treatment, and Risk for Dementia and Mild Cognitive Impairment: The Systolic Blood Pressure Intervention Trial. J Am Soc Nephrol. 2020 09; 31(9):2122-2132. PMID: 32591439.
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    11. Tran EM, Stefanick ML, Henderson VW, Rapp SR, Chen JC, Armstrong NM, Espeland MA, Gower EW, Shadyab AH, Li W, Stone KL, Pershing S. Association of Visual Impairment With Risk of Incident Dementia in a Women's Health Initiative Population. JAMA Ophthalmol. 2020 06 01; 138(6):624-633. PMID: 32297918.
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    12. Haring B, Liu J, Rapp SR, Shimbo D, Padula CB, Mozhui K, Li W, Espeland M, Wassertheil-Smoller S. Heart Rate, Brain Imaging Biomarkers and Cognitive Impairment in Older (=63 years) Women. Am J Cardiol. 2020 08 15; 129:102-108. PMID: 32576368.
      Citations:    
    13. Charles LE, Fekedulegn D, Burchfiel CM, Fujishiro K, Al Hazzouri AZ, Fitzpatrick AL, Rapp SR. Work Hours and Cognitive Function: The Multi-Ethnic Study of Atherosclerosis. Saf Health Work. 2020 Jun; 11(2):178-186. PMID: 32596013.
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    14. Armstrong NM, Espeland MA, Chen JC, Masaki K, Wactawski-Wende J, Li W, Gass MLS, Stefanick ML, Manson JE, Deal JA, Rapp SR, Lin FR, Resnick SM. Corrigendum to: Associations of Hearing Loss and Menopausal Hormone Therapy With Change in Global Cognition and Incident Cognitive Impairment Among Postmenopausal Women. J Gerontol A Biol Sci Med Sci. 2020 04 17; 75(5):1017. PMID: 31624848.
      Citations:    
    15. Armstrong NM, Espeland MA, Chen JC, Masaki K, Wactawski-Wende J, Li W, Gass MLS, Stefanick ML, Manson JE, Deal JA, Rapp SR, Lin FR, Resnick SM. Associations of Hearing Loss and Menopausal Hormone Therapy With Change in Global Cognition and Incident Cognitive Impairment Among Postmenopausal Women. J Gerontol A Biol Sci Med Sci. 2020 02 14; 75(3):537-544. PMID: 31326978.
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    16. Chlebowski RT, Rapp S, Aragaki AK, Pan K, Neuhouser ML, Snetselaar LG, Manson JE, Wactawski-Wende J, Johnson KC, Hayden K, Baker LD, Henderson VW, Garcia L, Qi L, Prentice RL. Low-fat dietary pattern and global cognitive function: Exploratory analyses of the Women's Health Initiative (WHI) randomized Dietary Modification trial. EClinicalMedicine. 2020 Jan; 18:100240. PMID: 31938786.
      Citations:    
    17. Younan D, Petkus AJ, Widaman KF, Wang X, Casanova R, Espeland MA, Gatz M, Henderson VW, Manson JE, Rapp SR, Sachs BC, Serre ML, Gaussoin SA, Barnard R, Saldana S, Vizuete W, Beavers DP, Salinas JA, Chui HC, Resnick SM, Shumaker SA, Chen JC. Particulate matter and episodic memory decline mediated by early neuroanatomic biomarkers of Alzheimer's disease. Brain. 2020 01 01; 143(1):289-302. PMID: 31746986.
      Citations:    
    18. Besser L, Galvin JE, Rodriguez D, Seeman T, Kukull W, Rapp SR, Smith J. Associations between neighborhood built environment and cognition vary by apolipoprotein E genotype: Multi-Ethnic Study of Atherosclerosis. Health Place. 2019 11; 60:102188. PMID: 31797769.
      Citations:    
    19. Lo K, Liu Q, Madsen T, Rapp S, Chen JC, Neuhouser M, Shadyab A, Pal L, Lin X, Shumaker S, Manson J, Feng YQ, Liu S. Relations of magnesium intake to cognitive impairment and dementia among participants in the Women's Health Initiative Memory Study: a prospective cohort study. BMJ Open. 2019 11 03; 9(11):e030052. PMID: 31685499.
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    20. Koch M, Fitzpatrick AL, Rapp SR, Nahin RL, Williamson JD, Lopez OL, DeKosky ST, Kuller LH, Mackey RH, Mukamal KJ, Jensen MK, Sink KM. Alcohol Consumption and Risk of Dementia and Cognitive Decline Among Older Adults With or Without Mild Cognitive Impairment. JAMA Netw Open. 2019 09 04; 2(9):e1910319. PMID: 31560382.
      Citations:    
    21. Wong SS, Case LD, Avis NE, Cummings TL, Cramer CK, Rapp SR. Cognitive functioning following brain irradiation as part of cancer treatment: Characterizing better cognitive performance. Psychooncology. 2019 11; 28(11):2166-2173. PMID: 31418491.
      Citations:    
    22. Still CH, Pajewski NM, Chelune GJ, Rapp SR, Sink KM, Wadley VG, Williamson JD, Lerner AJ. The Association between the Montreal Cognitive Assessment and Functional Activity Questionnaire in the Systolic Blood Pressure Intervention Trial (SPRINT). Arch Clin Neuropsychol. 2019 Aug 28; 34(6):814-824. PMID: 30517599.
      Citations:    
    23. Hayden KM, Gaussoin SA, Hunter JC, Manson JE, Sachs BC, Shadyab AH, Tindle HA, Mossavar-Rahmani Y, Mozhui K, Snively BM, Rapp SR, Resnick SM. Cognitive resilience among APOE e4 carriers in the oldest old. Int J Geriatr Psychiatry. 2019 12; 34(12):1833-1844. PMID: 31418472.
      Citations:    
    24. Nasrallah IM, Pajewski NM, Auchus AP, Chelune G, Cheung AK, Cleveland ML, Coker LH, Crowe MG, Cushman WC, Cutler JA, Davatzikos C, Desiderio L, Doshi J, Erus G, Fine LJ, Gaussoin SA, Harris D, Johnson KC, Kimmel PL, Kurella Tamura M, Launer LJ, Lerner AJ, Lewis CE, Martindale-Adams J, Moy CS, Nichols LO, Oparil S, Ogrocki PK, Rahman M, Rapp SR, Reboussin DM, Rocco MV, Sachs BC, Sink KM, Still CH, Supiano MA, Snyder JK, Wadley VG, Walker J, Weiner DE, Whelton PK, Wilson VM, Woolard N, Wright JT, Wright CB, Williamson JD, Bryan RN. Association of Intensive vs Standard Blood Pressure Control With Cerebral White Matter Lesions. JAMA. 2019 08 13; 322(6):524-534. PMID: 31408137.
      Citations:    
    25. Baker LD, Rapp SR, Shumaker SA, Manson JE, Sesso HD, Gaussoin SA, Harris D, Caudle B, Pleasants D, Espeland MA. Design and baseline characteristics of the cocoa supplement and multivitamin outcomes study for the Mind: COSMOS-Mind. Contemp Clin Trials. 2019 08; 83:57-63. PMID: 31271875.
      Citations:    
    26. Lopez OL, Chang Y, Ives DG, Snitz BE, Fitzpatrick AL, Carlson MC, Rapp SR, Williamson JD, Tracy RP, DeKosky ST, Kuller LH. Blood amyloid levels and risk of dementia in the Ginkgo Evaluation of Memory Study (GEMS): A longitudinal analysis. Alzheimers Dement. 2019 08; 15(8):1029-1038. PMID: 31255494.
      Citations:    
    27. Vajaranant TS, Hallak J, Espeland MA, Pasquale LR, Klein BE, Meuer SM, Rapp SR, Haan MN, Maki PM. An Association Between Large Optic Nerve Cupping and Cognitive Function. Am J Ophthalmol. 2019 10; 206:40-47. PMID: 31163134.
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    28. Gaussoin SA, Espeland MA, Beavers DP, Casanova R, Garcia KR, Snively BM, Shumaker SA, Wallace RB, Rapp SR. Dementia outcomes after addition of proxy-based assessments for deceased or proxy-dependent participants. Int J Geriatr Psychiatry. 2019 10; 34(10):1403-1411. PMID: 31034676.
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    29. Petkus AJ, Resnick SM, Rapp SR, Espeland MA, Gatz M, Widaman KF, Wang X, Younan D, Casanova R, Chui H, Barnard RT, Gaussoin S, Goveas JS, Hayden KM, Henderson VW, Sachs BC, Saldana S, Shadyab AH, Shumaker SA, Chen JC. General and domain-specific cognitive reserve, mild cognitive impairment, and dementia risk in older women. Alzheimers Dement (N Y). 2019; 5:118-128. PMID: 31011622.
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    30. Cramer CK, Cummings TL, Andrews RN, Strowd R, Rapp SR, Shaw EG, Chan MD, Lesser GJ. Treatment of Radiation-Induced Cognitive Decline in Adult Brain Tumor Patients. Curr Treat Options Oncol. 2019 04 08; 20(5):42. PMID: 30963289.
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    31. Driscoll I, Snively BM, Espeland MA, Shumaker SA, Rapp SR, Goveas JS, Casanova RL, Wactawski-Wende J, Manson JE, Rossom R, Brooks J, Hernandez DG, Singleton AB, Resnick SM. A candidate gene study of risk for dementia in older, postmenopausal women: Results from the Women's Health Initiative Memory Study. Int J Geriatr Psychiatry. 2019 05; 34(5):692-699. PMID: 30706571.
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    32. Mossavar-Rahmani Y, Kamensky V, Manson JE, Silver B, Rapp SR, Haring B, Beresford SAA, Snetselaar L, Wassertheil-Smoller S. Artificially Sweetened Beverages and Stroke, Coronary Heart Disease, and All-Cause Mortality in the Women's Health Initiative. Stroke. 2019 03; 50(3):555-562. PMID: 30802187.
      Citations:    
    33. Haring B, Liu J, Salmoirago-Blotcher E, Hayden KM, Sarto G, Roussouw J, Kuller LH, Rapp SR, Wassertheil-Smoller S. Blood pressure variability and brain morphology in elderly women without cardiovascular disease. Neurology. 2019 03 19; 92(12):e1284-e1297. PMID: 30814325.
      Citations:    
    34. Williamson JD, Pajewski NM, Auchus AP, Bryan RN, Chelune G, Cheung AK, Cleveland ML, Coker LH, Crowe MG, Cushman WC, Cutler JA, Davatzikos C, Desiderio L, Erus G, Fine LJ, Gaussoin SA, Harris D, Hsieh MK, Johnson KC, Kimmel PL, Tamura MK, Launer LJ, Lerner AJ, Lewis CE, Martindale-Adams J, Moy CS, Nasrallah IM, Nichols LO, Oparil S, Ogrocki PK, Rahman M, Rapp SR, Reboussin DM, Rocco MV, Sachs BC, Sink KM, Still CH, Supiano MA, Snyder JK, Wadley VG, Walker J, Weiner DE, Whelton PK, Wilson VM, Woolard N, Wright JT, Wright CB. Effect of Intensive vs Standard Blood Pressure Control on Probable Dementia: A Randomized Clinical Trial. JAMA. 2019 02 12; 321(6):553-561. PMID: 30688979.
      Citations:    
    35. Luo J, Manson JE, Weitlauf JC, Shadyab AH, Rapp SR, Garcia L, Miao Jonasson J, Tindle HA, Nassir R, Wactawski-Wende J, Hendryx M. Personality traits and diabetes incidence among postmenopausal women. Menopause. 2019 01 21; 26(6):629-636. PMID: 30672885.
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    36. Wanigatunga AA, Manini TM, Cook DR, Katula J, Fielding RA, Kramer AF, Verghese J, Rapp SR, Sink KM, King AC, Buford TW, Anton S, Nadkarni N, Jennings JM, Reid K, Espeland MA, Gill TM, Pahor M, Nocera JR. Community-Based Activity and Sedentary Patterns Are Associated With Cognitive Performance in Mobility-Limited Older Adults. Front Aging Neurosci. 2018; 10:341. PMID: 30498440.
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    37. Cramer CK, Alphonse-Sullivan N, Isom S, Metheny-Barlow LJ, Cummings TL, Page BR, Brown DR, Blackstock AW, Peiffer AM, Strowd RE, Rapp S, Lesser GJ, Shaw EG, Chan MD. Safety of pioglitazone during and after radiation therapy in patients with brain tumors: a phase I clinical trial. J Cancer Res Clin Oncol. 2019 Feb; 145(2):337-344. PMID: 30417218.
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    38. Cramer CK, McKee N, Case LD, Chan MD, Cummings TL, Lesser GJ, Shaw EG, Rapp SR. Mild cognitive impairment in long-term brain tumor survivors following brain irradiation. J Neurooncol. 2019 01; 141(1):235-244. PMID: 30406339.
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    39. Espeland MA, Dutton GR, Neiberg RH, Carmichael O, Hayden KM, Johnson KC, Jeffery RW, Baker LD, Cook DR, Kitzman DW, Rapp SR. Impact of a Multidomain Intensive Lifestyle Intervention on Complaints About Memory, Problem-Solving, and Decision-Making Abilities: The Action for Health in Diabetes Randomized Controlled Clinical Trial. J Gerontol A Biol Sci Med Sci. 2018 10 08; 73(11):1560-1567. PMID: 29846553.
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    40. Casanova R, Barnard RT, Gaussoin SA, Saldana S, Hayden KM, Manson JE, Wallace RB, Rapp SR, Resnick SM, Espeland MA, Chen JC. Using high-dimensional machine learning methods to estimate an anatomical risk factor for Alzheimer's disease across imaging databases. Neuroimage. 2018 12; 183:401-411. PMID: 30130645.
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    41. Espeland MA, Carmichael O, Yasar S, Hugenschmidt C, Hazzard W, Hayden KM, Rapp SR, Neiberg R, Johnson KC, Hoscheidt S, Mielke MM. Sex-related differences in the prevalence of cognitive impairment among overweight and obese adults with type 2 diabetes. Alzheimers Dement. 2018 09; 14(9):1184-1192. PMID: 30201101.
      Citations:    
    42. Espeland MA, Chen JC, Weitlauf J, Hayden KM, Rapp SR, Resnick SM, Garcia L, Cannell B, Baker LD, Sachs BC, Tindle HA, Wallace R, Casanova R. Trajectories of Relative Performance with 2 Measures of Global Cognitive Function. J Am Geriatr Soc. 2018 08; 66(8):1575-1580. PMID: 29972592.
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    43. Vitolins MZ, Case LD, Rapp SR, Lively MO, Shaw EG, Naughton MJ, Giguere J, Lesser GJ. Self-reported adherence and biomarker levels of CoQ10 and alpha-tocopherol. Patient Prefer Adherence. 2018; 12:637-646. PMID: 29731611.
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    44. Ong KL, Morris MJ, McClelland RL, Hughes TM, Maniam J, Fitzpatrick AL, Martin SS, Luchsinger JA, Rapp SR, Hayden KM, Sandfort V, Allison MA, Rye KA. Relationship of Lipids and Lipid-Lowering Medications With Cognitive Function: The Multi-Ethnic Study of Atherosclerosis. Am J Epidemiol. 2018 04 01; 187(4):767-776. PMID: 29617947.
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    45. Espeland MA, Carmichael O, Hayden K, Neiberg RH, Newman AB, Keller JN, Wadden TA, Rapp SR, Hill JO, Horton ES, Johnson KC, Wagenknecht L, Wing RR. Long-term Impact of Weight Loss Intervention on Changes in Cognitive Function: Exploratory Analyses from the Action for Health in Diabetes Randomized Controlled Clinical Trial. J Gerontol A Biol Sci Med Sci. 2018 03 14; 73(4):484-491. PMID: 28958022.
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    46. Korthauer LE, Goveas J, Espeland MA, Shumaker SA, Garcia KR, Tindle H, Salmoirago-Blotcher E, Sink KM, Vaughan L, Rapp SR, Resnick SM, Driscoll I. Negative Affect Is Associated With Higher Risk of Incident Cognitive Impairment in Nondepressed Postmenopausal Women. J Gerontol A Biol Sci Med Sci. 2018 03 14; 73(4):506-512. PMID: 29028908.
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    47. Rapp SR, Barnard RT, Sink KM, Chamberlain DG, Wilson V, Lu L, Ip EH. Computer simulations for assessing cognitively intensive instrumental activities of daily living in older adults. Alzheimers Dement (Amst). 2018; 10:237-244. PMID: 29560411.
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    48. Besser LM, Rodriguez DA, McDonald N, Kukull WA, Fitzpatrick AL, Rapp SR, Seeman T. Neighborhood built environment and cognition in non-demented older adults: The Multi-Ethnic Study of Atherosclerosis. Soc Sci Med. 2018 03; 200:27-35. PMID: 29355828.
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    49. Palta P, Carlson MC, Crum RM, Colantuoni E, Sharrett AR, Yasar S, Nahin RL, DeKosky ST, Snitz B, Lopez O, Williamson JD, Furberg CD, Rapp SR, Golden SH. Diabetes and Cognitive Decline in Older Adults: The Ginkgo Evaluation of Memory Study. J Gerontol A Biol Sci Med Sci. 2017 Dec 12; 73(1):123-130. PMID: 28510619.
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    50. Ip EH, Barnard R, Marshall SA, Lu L, Sink K, Wilson V, Chamberlain D, Rapp SR. Development of a video-simulation instrument for assessing cognition in older adults. BMC Med Inform Decis Mak. 2017 Dec 06; 17(1):161. PMID: 29212493.
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    51. Long KR, Lomonosova E, Li Q, Ponzar NL, Villa JA, Touchette E, Rapp S, Liley RM, Murelli RP, Grigoryan A, Buller RM, Wilson L, Bial J, Sagartz JE, Tavis JE. Efficacy of hepatitis B virus ribonuclease H inhibitors, a new class of replication antagonists, in FRG human liver chimeric mice. Antiviral Res. 2018 01; 149:41-47. PMID: 29129708.
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    52. Johnson DA, Lane J, Wang R, Reid M, Djonlagic I, Fitzpatrick AL, Rapp SR, Charles LE, O'Hara R, Saxena R, Redline S. Greater Cognitive Deficits with Sleep-disordered Breathing among Individuals with Genetic Susceptibility to Alzheimer Disease. The Multi-Ethnic Study of Atherosclerosis. Ann Am Thorac Soc. 2017 Nov; 14(11):1697-1705. PMID: 28731362.
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    53. Gifford AR, Lawrence JA, Baker LD, Balcueva EP, Case D, Craft S, Curtis AE, Griffin L, Groteluschen DL, Klepin HD, Lesser GJ, Messino MJ, Naughton M, Samuel TA, Rapp S, Sachs B, Sink KM, Williamson J, Shaw EG. National Institute on Aging /Alzheimer's Association criteria for Mild Cognitive Impairment applied to chemotherapy treated breast cancer survivors. J Oncol Research. 2017; 1(1). PMID: 29873324.
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    54. Hayden KM, Baker LD, Bray G, Carvajal R, Demos-McDermott K, Hergenroeder AL, Hill JO, Horton E, Jakicic JM, Johnson KC, Neiberg RH, Rapp SR, Wadden TA, Miller ME. Long-term impact of intensive lifestyle intervention on cognitive function assessed with the National Institutes of Health Toolbox: The Look AHEAD study. Alzheimers Dement (Amst). 2018; 10:41-48. PMID: 29159267.
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    55. Tindle HA, Duncan MS, Liu S, Kuller LH, Fugate Woods N, Rapp SR, Kroenke CH, Coday M, Loucks EB, Lamonte MJ, Progovac AM, Salmoirago-Blotcher E, Walitt BT, Yuo NY, Freiberg MS. Optimism, pessimism, cynical hostility, and biomarkers of metabolic function in the Women's Health Initiative. J Diabetes. 2018 Jun; 10(6):512-523. PMID: 28703425.
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    56. Mozhui K, Snively BM, Rapp SR, Wallace RB, Williams RW, Johnson KC. Genetic Analysis of Mitochondrial Ribosomal Proteins and Cognitive Aging in Postmenopausal Women. Front Genet. 2017; 8:127. PMID: 28983317.
      Citations:    
    57. Naughton MJ, Case LD, Peiffer A, Chan M, Stieber V, Moore D, Falchuk S, Piephoff J, Edenfield W, Giguere J, Loghin M, Shaw EG, Rapp SR. Quality of life of irradiated brain tumor survivors treated with donepezil or placebo: Results of the WFU CCOP research base protocol 91105. Neurooncol Pract. 2018 May; 5(2):114-121. PMID: 29770225.
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    58. Espeland MA, Rapp SR, Manson JE, Goveas JS, Shumaker SA, Hayden KM, Weitlauf JC, Gaussoin SA, Baker LD, Padula CB, Hou L, Resnick SM. Long-term Effects on Cognitive Trajectories of Postmenopausal Hormone Therapy in Two Age Groups. J Gerontol A Biol Sci Med Sci. 2017 Jun 01; 72(6):838-845. PMID: 27506836.
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    59. Hayden KM, Beavers DP, Steck SE, Hebert JR, Tabung FK, Shivappa N, Casanova R, Manson JE, Padula CB, Salmoirago-Blotcher E, Snetselaar LG, Zaslavsky O, Rapp SR. The association between an inflammatory diet and global cognitive function and incident dementia in older women: The Women's Health Initiative Memory Study. Alzheimers Dement. 2017 Nov; 13(11):1187-1196. PMID: 28531379.
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    60. Fujiyoshi A, Jacobs DR, Fitzpatrick AL, Alonso A, Duprez DA, Sharrett AR, Seeman T, Blaha MJ, Luchsinger JA, Rapp SR. Coronary Artery Calcium and Risk of Dementia in MESA (Multi-Ethnic Study of Atherosclerosis). Circ Cardiovasc Imaging. 2017 May; 10(5). PMID: 28465455.
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    61. Espeland MA, Luchsinger JA, Baker LD, Neiberg R, Kahn SE, Arnold SE, Wing RR, Blackburn GL, Bray G, Evans M, Hazuda HP, Jeffery RW, Wilson VM, Clark JM, Coday M, Demos-McDermott K, Foreyt JP, Greenway F, Hill JO, Horton ES, Jakicic JM, Johnson KC, Knowler WC, Lewis CE, Nathan DM, Peters A, Pi-Sunyer X, Pownall H, Wadden TA, Rapp SR. Effect of a long-term intensive lifestyle intervention on prevalence of cognitive impairment. Neurology. 2017 May 23; 88(21):2026-2035. PMID: 28446656.
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    62. Fujiyoshi A, Jacobs DR, Alonso A, Luchsinger JA, Rapp SR, Duprez DA. Validity of Death Certificate and Hospital Discharge ICD Codes for Dementia Diagnosis: The Multi-Ethnic Study of Atherosclerosis. Alzheimer Dis Assoc Disord. 2017 Apr-Jun; 31(2):168-172. PMID: 27819846.
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    63. Hughes TM, Craft S, Baker LD, Espeland MA, Rapp SR, Sink KM, Bertoni AG, Burke GL, Gottesman RF, Michos ED, Luchsinger JA, Fitzpatrick AL, Hayden KM. Changes in metabolic risk factors over 10 years and their associations with late-life cognitive performance: The Multi-Ethnic Study of Atherosclerosis. Alzheimers Dement (Amst). 2017; 8:18-25. PMID: 28435852.
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    64. Rapp SR, Luchsinger JA, Baker LD, Blackburn GL, Hazuda HP, Demos-McDermott KE, Jeffery RW, Keller JN, McCaffery JM, Pajewski NM, Evans M, Wadden TA, Arnold SE, Espeland MA. Effect of a Long-Term Intensive Lifestyle Intervention on Cognitive Function: Action for Health in Diabetes Study. J Am Geriatr Soc. 2017 May; 65(5):966-972. PMID: 28067945.
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    65. Beavers KM, Leng I, Rapp SR, Miller ME, Houston DK, Marsh AP, Hire DG, Baker LD, Bray GA, Blackburn GL, Hergenroeder AL, Jakicic JM, Johnson KC, Korytkowski MT, Dorsten BV, Kritchevsky SB. Effects of Longitudinal Glucose Exposure on Cognitive and Physical Function: Results from the Action for Health in Diabetes Movement and Memory Study. J Am Geriatr Soc. 2017 01; 65(1):137-145. PMID: 27676466.
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    66. Camacho Á, McClelland RL, Delaney JA, Allison MA, Psaty BM, Rifkin DE, Rapp SR, Szklo M, Stein MB, Criqui MH. Antidepressant Use and Subclinical Measures of Atherosclerosis: The Multi-Ethnic Study of Atherosclerosis. J Clin Psychopharmacol. 2016 Aug; 36(4):340-6. PMID: 27269959.
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    67. Mezuk B, Choi M, DeSantis AS, Rapp SR, Diez Roux AV, Seeman T. Loneliness, Depression, and Inflammation: Evidence from the Multi-Ethnic Study of Atherosclerosis. PLoS One. 2016; 11(7):e0158056. PMID: 27367428.
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    68. Goveas JS, Rapp SR, Hogan PE, Driscoll I, Tindle HA, Smith JC, Kesler SR, Zaslavsky O, Rossom RC, Ockene JK, Yaffe K, Manson JE, Resnick SM, Espeland MA. Predictors of Optimal Cognitive Aging in 80+ Women: The Women's Health Initiative Memory Study. J Gerontol A Biol Sci Med Sci. 2016 Mar; 71 Suppl 1:S62-71. PMID: 26858326.
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    69. Vaughan L, Redline S, Stone K, Ulanski J, Rueschman M, Dailey H, Rapp SR, Snively BM, Baker LD, Shumaker SA. Feasibility of self-administered sleep assessment in older women in the Women's Health Initiative (WHI). Sleep Breath. 2016 Sep; 20(3):1079-91. PMID: 26825380.
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    70. Rapp SR, LaCroix AZ, Shumaker SA. Living Long and Living Well: Results from the Women's Health Initiative. J Gerontol A Biol Sci Med Sci. 2016 Mar; 71 Suppl 1:S100-2. PMID: 26684787.
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    71. Rapp SR, LaCroix AZ, Shumaker SA. Living Well After 80 Years: An Introduction to the Special Issue. J Gerontol A Biol Sci Med Sci. 2016 Mar; 71 Suppl 1:S1-2. PMID: 26672613.
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    72. Vaughan L, Hogan PE, Rapp SR, Dugan E, Marottoli RA, Snively BM, Shumaker SA, Sink KM. Driving with Mild Cognitive Impairment or Dementia: Cognitive Test Performance and Proxy Report of Daily Life Function in Older Women. J Am Geriatr Soc. 2015 Sep; 63(9):1774-82. PMID: 26338449.
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    73. Sink KM, Espeland MA, Castro CM, Church T, Cohen R, Dodson JA, Guralnik J, Hendrie HC, Jennings J, Katula J, Lopez OL, McDermott MM, Pahor M, Reid KF, Rushing J, Verghese J, Rapp S, Williamson JD. Effect of a 24-Month Physical Activity Intervention vs Health Education on Cognitive Outcomes in Sedentary Older Adults: The LIFE Randomized Trial. JAMA. 2015 Aug 25; 314(8):781-90. PMID: 26305648.
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    74. Bell CL, LaCroix AZ, Desai M, Hedlin H, Rapp SR, Cene C, Savla J, Shippee T, Wassertheil-Smoller S, Stefanick ML, Masaki K. Factors Associated with Nursing Home Admission after Stroke in Older Women. J Stroke Cerebrovasc Dis. 2015 Oct; 24(10):2329-37. PMID: 26169547.
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    75. Lawrence JA, Griffin L, Balcueva EP, Groteluschen DL, Samuel TA, Lesser GJ, Naughton MJ, Case LD, Shaw EG, Rapp SR. A study of donepezil in female breast cancer survivors with self-reported cognitive dysfunction 1 to 5 years following adjuvant chemotherapy. J Cancer Surviv. 2016 Feb; 10(1):176-84. PMID: 26130292.
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    76. Page BR, Shaw EG, Lu L, Bryant D, Grisell D, Lesser GJ, Monitto DC, Naughton MJ, Rapp SR, Savona SR, Shah S, Case D, Chan MD. Phase II double-blind placebo-controlled randomized study of armodafinil for brain radiation-induced fatigue. Neuro Oncol. 2015 Oct; 17(10):1393-401. PMID: 25972454.
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    77. Rapp SR, Case LD, Peiffer A, Naughton MM, Chan MD, Stieber VW, Moore DF, Falchuk SC, Piephoff JV, Edenfield WJ, Giguere JK, Loghin ME, Shaw EG. Donepezil for Irradiated Brain Tumor Survivors: A Phase III Randomized Placebo-Controlled Clinical Trial. J Clin Oncol. 2015 May 20; 33(15):1653-9. PMID: 25897156.
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    78. Fitzpatrick AL, Rapp SR, Luchsinger J, Hill-Briggs F, Alonso A, Gottesman R, Lee H, Carnethon M, Liu K, Williams K, Sharrett AR, Frazier-Wood A, Lyketsos C, Seeman T. Sociodemographic Correlates of Cognition in the Multi-Ethnic Study of Atherosclerosis (MESA). Am J Geriatr Psychiatry. 2015 Jul; 23(7):684-97. PMID: 25704999.
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    79. Vaughan L, Erickson KI, Espeland MA, Smith JC, Tindle HA, Rapp SR. Concurrent and longitudinal relationships between cognitive activity, cognitive performance, and brain volume in older adult women. J Gerontol B Psychol Sci Soc Sci. 2014 Nov; 69(6):826-36. PMID: 25209372.
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    80. Sink KM, Espeland MA, Rushing J, Castro CM, Church TS, Cohen R, Gill TM, Henkin L, Jennings JM, Kerwin DR, Manini TM, Myers V, Pahor M, Reid KF, Woolard N, Rapp SR, Williamson JD. The LIFE Cognition Study: design and baseline characteristics. Clin Interv Aging. 2014; 9:1425-36. PMID: 25210447.
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    81. Espeland MA, Rapp SR, Bray GA, Houston DK, Johnson KC, Kitabchi AE, Hergenroeder AL, Williamson J, Jakicic JM, van Dorsten B, Kritchevsky SB. Long-term impact of behavioral weight loss intervention on cognitive function. J Gerontol A Biol Sci Med Sci. 2014 Sep; 69(9):1101-8. PMID: 24619151.
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    82. Vaughan L, Leng I, Dagenbach D, Resnick SM, Rapp SR, Jennings JM, Brunner RL, Simpson SL, Beavers DP, Coker LH, Gaussoin SA, Sink KM, Espeland MA. Intraindividual variability in domain-specific cognition and risk of mild cognitive impairment and dementia. Curr Gerontol Geriatr Res. 2013; 2013:495793. PMID: 24454359.
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    83. Klepin HD, Geiger AM, Bandos H, Costantino JP, Rapp SR, Sink KM, Lawrence JA, Atkinson HH, Espeland MA. Cognitive factors associated with adherence to oral antiestrogen therapy: results from the cognition in the study of tamoxifen and raloxifene (Co-STAR) study. Cancer Prev Res (Phila). 2014 Jan; 7(1):161-8. PMID: 24253314.
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    84. Casanova R, Hsu FC, Sink KM, Rapp SR, Williamson JD, Resnick SM, Espeland MA. Alzheimer's disease risk assessment using large-scale machine learning methods. PLoS One. 2013; 8(11):e77949. PMID: 24250789.
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    85. Espeland MA, Shumaker SA, Leng I, Manson JE, Brown CM, LeBlanc ES, Vaughan L, Robinson J, Rapp SR, Goveas JS, Wactawski-Wende J, Stefanick ML, Li W, Resnick SM. Long-term effects on cognitive function of postmenopausal hormone therapy prescribed to women aged 50 to 55 years. JAMA Intern Med. 2013 Aug 12; 173(15):1429-36. PMID: 23797469.
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    86. Espeland MA, Katula JA, Rushing J, Kramer AF, Jennings JM, Sink KM, Nadkarni NK, Reid KF, Castro CM, Church T, Kerwin DR, Williamson JD, Marottoli RA, Rushing S, Marsiske M, Rapp SR. Performance of a computer-based assessment of cognitive function measures in two cohorts of seniors. Int J Geriatr Psychiatry. 2013 Dec; 28(12):1239-50. PMID: 23589390.
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    87. Vaughan L, Espeland MA, Snively B, Shumaker SA, Rapp SR, Shupe J, Robinson JG, Sarto GE, Resnick SM. The rationale, design, and baseline characteristics of the Women's Health Initiative Memory Study of Younger Women (WHIMS-Y). Brain Res. 2013 Jun 13; 1514:3-11. PMID: 23578696.
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    88. Peiffer AM, Leyrer CM, Greene-Schloesser DM, Shing E, Kearns WT, Hinson WH, Tatter SB, Ip EH, Rapp SR, Robbins ME, Shaw EG, Chan MD. Neuroanatomical target theory as a predictive model for radiation-induced cognitive decline. Neurology. 2013 Feb 19; 80(8):747-53. PMID: 23390169.
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    89. Rapp SR, Espeland MA, Manson JE, Resnick SM, Bryan NR, Smoller S, Coker LH, Phillips LS, Stefanick ML, Sarto GE. Educational attainment, MRI changes, and cognitive function in older postmenopausal women from the Women's Health Initiative Memory Study. Int J Psychiatry Med. 2013; 46(2):121-43. PMID: 24552037.
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    90. Danhauer SC, Legault C, Bandos H, Kidwell K, Costantino J, Vaughan L, Avis NE, Rapp S, Coker LH, Naughton M, Naylor C, Terracciano A, Shumaker S. Positive and negative affect, depression, and cognitive processes in the Cognition in the Study of Tamoxifen and Raloxifene (Co-STAR) Trial. Neuropsychol Dev Cogn B Aging Neuropsychol Cogn. 2013; 20(5):532-52. PMID: 23237718.
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    91. Rapp SR, Legault C, Espeland MA, Resnick SM, Hogan PE, Coker LH, Dailey M, Shumaker SA. Validation of a cognitive assessment battery administered over the telephone. J Am Geriatr Soc. 2012 Sep; 60(9):1616-23. PMID: 22985137.
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    92. Attia A, Rapp SR, Case LD, D'Agostino R, Lesser G, Naughton M, McMullen K, Rosdhal R, Shaw EG. Phase II study of Ginkgo biloba in irradiated brain tumor patients: effect on cognitive function, quality of life, and mood. J Neurooncol. 2012 Sep; 109(2):357-63. PMID: 22700031.
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    93. O'Neill JL, Chan YH, Rapp SR, Yosipovitch G. Differences in itch characteristics between psoriasis and atopic dermatitis patients: results of a web-based questionnaire. Acta Derm Venereol. 2011 Sep; 91(5):537-40. PMID: 21533325.
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    94. Legault C, Jennings JM, Katula JA, Dagenbach D, Gaussoin SA, Sink KM, Rapp SR, Rejeski WJ, Shumaker SA, Espeland MA. Designing clinical trials for assessing the effects of cognitive training and physical activity interventions on cognitive outcomes: the Seniors Health and Activity Research Program Pilot (SHARP-P) study, a randomized controlled trial. BMC Geriatr. 2011 May 26; 11:27. PMID: 21615936.
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    95. Gaussoin SA, Espeland MA, Absher J, Howard BV, Jones BM, Rapp SR. Ascertaining dementia-related outcomes for deceased or proxy-dependent participants: an overview of the Women's Health Initiative Memory Study supplemental case ascertainment protocol. Int J Geriatr Psychiatry. 2012 Feb; 27(2):205-14. PMID: 21416508.
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    96. Salmoirago-Blotcher E, Fitchett G, Ockene JK, Schnall E, Crawford S, Granek I, Manson J, Ockene I, O'Sullivan MJ, Powell L, Rapp S. Religion and healthy lifestyle behaviors among postmenopausal women: the women's health initiative. J Behav Med. 2011 Oct; 34(5):360-71. PMID: 21301947.
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    97. Espeland MA, Rapp SR, Katula JA, Andrews LA, Felton D, Gaussoin SA, Dagenbach D, Legault C, Jennings JM, Sink KM. Telephone interview for cognitive status (TICS) screening for clinical trials of physical activity and cognitive training: the seniors health and activity research program pilot (SHARP-P) study. Int J Geriatr Psychiatry. 2011 Feb; 26(2):135-43. PMID: 21229597.
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    98. Bettermann K, Arnold AM, Williamson J, Rapp S, Sink K, Toole JF, Carlson MC, Yasar S, Dekosky S, Burke GL. Statins, risk of dementia, and cognitive function: secondary analysis of the ginkgo evaluation of memory study. J Stroke Cerebrovasc Dis. 2012 Aug; 21(6):436-44. PMID: 21236699.
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    99. Wylie-Rosett J, Aragaki AK, Cochrane B, Perri MG, Rosal MC, Rapp SR. Cynicism: Incident diabetes and worsening of metabolic syndrome in postmenopausal women. Diabetes Metab Syndr. 2010 Oct-Dec; 4(4):187-189. PMID: 25663951.
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    100. Rapp SR, Legault C, Henderson VW, Brunner RL, Masaki K, Jones B, Absher J, Thal L. Subtypes of mild cognitive impairment in older postmenopausal women: the Women's Health Initiative Memory Study. Alzheimer Dis Assoc Disord. 2010 Jul-Sep; 24(3):248-55. PMID: 20473134.
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    101. Espeland MA, Brunner RL, Hogan PE, Rapp SR, Coker LH, Legault C, Granek I, Resnick SM. Long-term effects of conjugated equine estrogen therapies on domain-specific cognitive function: results from the Women's Health Initiative study of cognitive aging extension. J Am Geriatr Soc. 2010 Jul; 58(7):1263-71. PMID: 20649689.
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    102. Mair C, Diez Roux AV, Osypuk TL, Rapp SR, Seeman T, Watson KE. Is neighborhood racial/ethnic composition associated with depressive symptoms? The multi-ethnic study of atherosclerosis. Soc Sci Med. 2010 Aug; 71(3):541-550. PMID: 20541303.
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    103. Parlow JJ, Burney MW, Case BL, Girard TJ, Hall KA, Harris PK, Hiebsch RR, Huff RM, Lachance RM, Mischke DA, Rapp SR, Woerndle RS, Ennis MD. Piperazinyl glutamate pyridines as potent orally bioavailable P2Y12 antagonists for inhibition of platelet aggregation. J Med Chem. 2010 Mar 11; 53(5):2010-37. PMID: 20141147.
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    104. Espeland MA, Shumaker SA, Limacher M, Rapp SR, Bevers TB, Barad DH, Coker LH, Gaussoin SA, Stefanick ML, Lane DS, Maki PM, Resnick SM. Relative effects of tamoxifen, raloxifene, and conjugated equine estrogens on cognition. J Womens Health (Larchmt). 2010 Mar; 19(3):371-9. PMID: 20136553.
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    105. Colenda CC, Legault C, Rapp SR, DeBon MW, Hogan P, Wallace R, Hershey L, Ockene J, Whitmer R, Phillips LS, Sarto GE. Psychiatric disorders and cognitive dysfunction among older, postmenopausal women: results from the Women's Health Initiative Memory Study. Am J Geriatr Psychiatry. 2010 Feb; 18(2):177-86. PMID: 20104074.
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    106. Parlow JJ, Burney MW, Case BL, Girard TJ, Hall KA, Harris PK, Hiebsch RR, Huff RM, Lachance RM, Mischke DA, Rapp SR, Woerndle RS, Ennis MD. Part II: piperazinyl-glutamate-pyridines as potent orally bioavailable P2Y12 antagonists for inhibition of platelet aggregation. Bioorg Med Chem Lett. 2010 Feb 15; 20(4):1388-94. PMID: 20097563.
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    107. Snitz BE, O'Meara ES, Carlson MC, Arnold AM, Ives DG, Rapp SR, Saxton J, Lopez OL, Dunn LO, Sink KM, DeKosky ST. Ginkgo biloba for preventing cognitive decline in older adults: a randomized trial. JAMA. 2009 Dec 23; 302(24):2663-70. PMID: 20040554.
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    108. Coker LH, Espeland MA, Rapp SR, Legault C, Resnick SM, Hogan P, Gaussoin S, Dailey M, Shumaker SA. Postmenopausal hormone therapy and cognitive outcomes: the Women's Health Initiative Memory Study (WHIMS). J Steroid Biochem Mol Biol. 2010 Feb 28; 118(4-5):304-10. PMID: 19932751.
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    109. Resnick SM, Espeland MA, An Y, Maki PM, Coker LH, Jackson R, Stefanick ML, Wallace R, Rapp SR. Effects of conjugated equine estrogens on cognition and affect in postmenopausal women with prior hysterectomy. J Clin Endocrinol Metab. 2009 Nov; 94(11):4152-61. PMID: 19850684.
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    110. Atkinson HH, Rapp SR, Williamson JD, Lovato J, Absher JR, Gass M, Henderson VW, Johnson KC, Kostis JB, Sink KM, Mouton CP, Ockene JK, Stefanick ML, Lane DS, Espeland MA. The relationship between cognitive function and physical performance in older women: results from the women's health initiative memory study. J Gerontol A Biol Sci Med Sci. 2010 Mar; 65(3):300-6. PMID: 19789197.
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    111. Parlow JJ, Burney MW, Case BL, Girard TJ, Hall KA, Hiebsch RR, Huff RM, Lachance RM, Mischke DA, Rapp SR, Woerndle RS, Ennis MD. Piperazinyl-glutamate-pyrimidines as potent P2Y12 antagonists for inhibition of platelet aggregation. Bioorg Med Chem Lett. 2009 Nov 01; 19(21):6148-56. PMID: 19796941.
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    112. Parlow JJ, Burney MW, Case BL, Girard TJ, Hall KA, Hiebsch RR, Huff RM, Lachance RM, Mischke DA, Rapp SR, Woerndle RS, Ennis MD. Piperazinyl-glutamate-pyridines as potent orally bioavailable P2Y12 antagonists for inhibition of platelet aggregation. Bioorg Med Chem Lett. 2009 Aug 15; 19(16):4657-63. PMID: 19604694.
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    113. Snitz BE, Saxton J, Lopez OL, Ives DG, Dunn LO, Rapp SR, Carlson MC, Fitzpatrick AL, Dekosky ST. Identifying mild cognitive impairment at baseline in the Ginkgo Evaluation of Memory (GEM) study. Aging Ment Health. 2009 Mar; 13(2):171-82. PMID: 19347684.
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    114. Keen SB, Yelverton CB, Rapp SR, Feldman SR. UV light abuse as a substance-related disorder: clinical implications. Arch Dermatol. 2008 Aug; 144(8):1047-8. PMID: 18711080.
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    115. Vallejos QM, Schulz MR, Quandt SA, Feldman SR, Galvan L, Verma A, Fleischer AB, Rapp SR, Arcury TA. Self report of skin problems among farmworkers in North Carolina. Am J Ind Med. 2008 Mar; 51(3):204-12. PMID: 18181182.
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    116. Quandt SA, Schulz MR, Vallejos QM, Feldman SR, Verma A, Fleischer AB, Rapp SR, Arcury TA. The association of dermatologist-diagnosed and self-reported skin diseases with skin-related quality of life in Latino migrant farmworkers. Int J Dermatol. 2008 Mar; 47(3):236-41. PMID: 18289322.
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    117. Rijmen F, Ip EH, Rapp S, Shaw EG. Qualitative longitudinal analysis of symptoms in patients with primary and metastatic brain tumours. J R Stat Soc Ser A Stat Soc. 2008; 171(3):739-753. PMID: 27881905.
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    118. Gleason JF, Case D, Rapp SR, Ip E, Naughton M, Butler JM, McMullen K, Stieber V, Saconn P, Shaw EG. Symptom clusters in patients with newly-diagnosed brain tumors. J Support Oncol. 2007 Oct; 5(9):427-33, 436. PMID: 18019850.
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    119. Butler JM, Case LD, Atkins J, Frizzell B, Sanders G, Griffin P, Lesser G, McMullen K, McQuellon R, Naughton M, Rapp S, Stieber V, Shaw EG. A phase III, double-blind, placebo-controlled prospective randomized clinical trial of d-threo-methylphenidate HCl in brain tumor patients receiving radiation therapy. Int J Radiat Oncol Biol Phys. 2007 Dec 01; 69(5):1496-501. PMID: 17869448.
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    120. Atkinson HH, Rosano C, Simonsick EM, Williamson JD, Davis C, Ambrosius WT, Rapp SR, Cesari M, Newman AB, Harris TB, Rubin SM, Yaffe K, Satterfield S, Kritchevsky SB. Cognitive function, gait speed decline, and comorbidities: the health, aging and body composition study. J Gerontol A Biol Sci Med Sci. 2007 Aug; 62(8):844-50. PMID: 17702875.
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    121. Butler JM, Rapp SR, Shaw EG. Managing the cognitive effects of brain tumor radiation therapy. Curr Treat Options Oncol. 2006 Nov; 7(6):517-23. PMID: 17032563.
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    122. Espeland MA, Coker LH, Wallace R, Rapp SR, Resnick SM, Limacher M, Powell LH, Messina CR. Association between alcohol intake and domain-specific cognitive function in older women. Neuroepidemiology. 2006; 27(1):1-12. PMID: 16717476.
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    123. Hendrix SL, Wassertheil-Smoller S, Johnson KC, Howard BV, Kooperberg C, Rossouw JE, Trevisan M, Aragaki A, Baird AE, Bray PF, Buring JE, Criqui MH, Herrington D, Lynch JK, Rapp SR, Torner J. Effects of conjugated equine estrogen on stroke in the Women's Health Initiative. Circulation. 2006 May 23; 113(20):2425-34. PMID: 16702472.
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    124. Kaur M, Liguori A, Lang W, Rapp SR, Fleischer AB, Feldman SR. Induction of withdrawal-like symptoms in a small randomized, controlled trial of opioid blockade in frequent tanners. J Am Acad Dermatol. 2006 Apr; 54(4):709-11. PMID: 16546596.
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    125. Shaw EG, Rosdhal R, D'Agostino RB, Lovato J, Naughton MJ, Robbins ME, Rapp SR. Phase II study of donepezil in irradiated brain tumor patients: effect on cognitive function, mood, and quality of life. J Clin Oncol. 2006 Mar 20; 24(9):1415-20. PMID: 16549835.
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    126. Resnick SM, Maki PM, Rapp SR, Espeland MA, Brunner R, Coker LH, Granek IA, Hogan P, Ockene JK, Shumaker SA. Effects of combination estrogen plus progestin hormone treatment on cognition and affect. J Clin Endocrinol Metab. 2006 May; 91(5):1802-10. PMID: 16522699.
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    127. Rosenquist PB, Dunn A, Rapp S, Gaba A, McCall WV. What predicts patients' expressed likelihood of choosing electroconvulsive therapy as a future treatment option? J ECT. 2006 Mar; 22(1):33-7. PMID: 16633204.
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    128. Balkrishnan R, McMichael AJ, Hu JY, Camacho FT, Shew KR, Bouloc A, Rapp SR, Feldman SR. Correlates of health-related quality of life in women with severe facial blemishes. Int J Dermatol. 2006 Feb; 45(2):111-5. PMID: 16445498.
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    129. Rapp SR, Feldman SR, Graham G, Fleischer AB, Brenes G, Dailey M. The Acne Quality of Life Index (Acne-QOLI): development and validation of a brief instrument. Am J Clin Dermatol. 2006; 7(3):185-92. PMID: 16734506.
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    130. Espeland MA, Rapp SR, Robertson J, Granek I, Murphy C, Albert M, Bassford T. Benchmarks for designing two-stage studies using modified mini-mental state examinations: experience from the Women's Health Initiative Memory Study. Clin Trials. 2006; 3(2):99-106. PMID: 16773952.
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    131. Krejci-Manwaring J, Kerchner K, Feldman SR, Rapp DA, Rapp SR. Social sensitivity and acne: the role of personality in negative social consequences and quality of life. Int J Psychiatry Med. 2006; 36(1):121-30. PMID: 16927583.
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    132. Vallejos QM, Marin AJ, Feldman SR, Krejci-Manwaring J, Fleischer A, Quandt SA, Schulz M, Smith G, Rapp SR, Arcury TA. Spanish dermatological vocabulary used by Mexican workers. Dermatol Online J. 2005 Aug 01; 11(2):32. PMID: 16150240.
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    133. Balkrishnan R, McMichael AJ, Hu JY, Camacho FT, Kaur M, Bouloc A, Rapp SR, Feldman SR. Corrective cosmetics are effective for women with facial pigmentary disorders. Cutis. 2005 Mar; 75(3):181-7. PMID: 15839363.
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    134. Espeland MA, Gu L, Masaki KH, Langer RD, Coker LH, Stefanick ML, Ockene J, Rapp SR. Association between reported alcohol intake and cognition: results from the Women's Health Initiative Memory Study. Am J Epidemiol. 2005 Feb 01; 161(3):228-38. PMID: 15671255.
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    135. Feldman SR, Liguori A, Kucenic M, Rapp SR, Fleischer AB, Lang W, Kaur M. Ultraviolet exposure is a reinforcing stimulus in frequent indoor tanners. J Am Acad Dermatol. 2004 Jul; 51(1):45-51. PMID: 15243523.
      Citations:    
    136. Balkrishnan R, Manuel J, Feldman SR, Rapp SR. Measurement of health-related quality of life (HRQOL) associated with skin disease. J Am Acad Dermatol. 2004 Jul; 51(1 Suppl):S3-4. PMID: 15243486.
      Citations:    
    137. Shumaker SA, Legault C, Kuller L, Rapp SR, Thal L, Lane DS, Fillit H, Stefanick ML, Hendrix SL, Lewis CE, Masaki K, Coker LH. Conjugated equine estrogens and incidence of probable dementia and mild cognitive impairment in postmenopausal women: Women's Health Initiative Memory Study. JAMA. 2004 Jun 23; 291(24):2947-58. PMID: 15213206.
      Citations:    
    138. Espeland MA, Rapp SR, Shumaker SA, Brunner R, Manson JE, Sherwin BB, Hsia J, Margolis KL, Hogan PE, Wallace R, Dailey M, Freeman R, Hays J. Conjugated equine estrogens and global cognitive function in postmenopausal women: Women's Health Initiative Memory Study. JAMA. 2004 Jun 23; 291(24):2959-68. PMID: 15213207.
      Citations:    
    139. Klein KP, Rapp SR. Women's cognitive health: postmenopausal dementia and the women's health initiative memory study. Womens Health Issues. 2004 May-Jun; 14(3):71-4. PMID: 15193634.
      Citations:    
    140. Rapp SR, Feldman SR. The promise and challenge of new biological treatments for psoriasis: how do they impact quality of life? Dermatol Ther. 2004; 17(5):376-82. PMID: 15379772.
      Citations:    
    141. Resnick SM, Coker LH, Maki PM, Rapp SR, Espeland MA, Shumaker SA. The Women's Health Initiative Study of Cognitive Aging (WHISCA): a randomized clinical trial of the effects of hormone therapy on age-associated cognitive decline. Clin Trials. 2004; 1(5):440-50. PMID: 16279282.
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    142. Pettey AA, Balkrishnan R, Rapp SR, Fleischer AB, Feldman SR. Patients with palmoplantar psoriasis have more physical disability and discomfort than patients with other forms of psoriasis: implications for clinical practice. J Am Acad Dermatol. 2003 Aug; 49(2):271-5. PMID: 12894076.
      Citations:    
    143. Bhat BG, Rapp SR, Beaudry JA, Napawan N, Butteiger DN, Hall KA, Null CL, Luo Y, Keller BT. Inhibition of ileal bile acid transport and reduced atherosclerosis in apoE-/- mice by SC-435. J Lipid Res. 2003 Sep; 44(9):1614-21. PMID: 12810816.
      Citations:    
    144. Shumaker SA, Legault C, Rapp SR, Thal L, Wallace RB, Ockene JK, Hendrix SL, Jones BN, Assaf AR, Jackson RD, Kotchen JM, Wassertheil-Smoller S, Wactawski-Wende J. Estrogen plus progestin and the incidence of dementia and mild cognitive impairment in postmenopausal women: the Women's Health Initiative Memory Study: a randomized controlled trial. JAMA. 2003 May 28; 289(20):2651-62. PMID: 12771112.
      Citations:    
    145. Rapp SR, Espeland MA, Shumaker SA, Henderson VW, Brunner RL, Manson JE, Gass ML, Stefanick ML, Lane DS, Hays J, Johnson KC, Coker LH, Dailey M, Bowen D. Effect of estrogen plus progestin on global cognitive function in postmenopausal women: the Women's Health Initiative Memory Study: a randomized controlled trial. JAMA. 2003 May 28; 289(20):2663-72. PMID: 12771113.
      Citations:    
    146. Balkrishnan R, Housman TS, Grummer S, Rapp SR, Clarke J, Feldman SR, Fleischer AB. The family impact of atopic dermatitis in children: the role of the parent caregiver. Pediatr Dermatol. 2003 Jan-Feb; 20(1):5-10. PMID: 12558838.
      Citations:    
    147. Housman TS, Mellen BG, Rapp SR, Fleischer AB, Feldman SR. Patients with psoriasis prefer solution and foam vehicles: a quantitative assessment of vehicle preference. Cutis. 2002 Dec; 70(6):327-32. PMID: 12502121.
      Citations:    
    148. Huff MW, Telford DE, Edwards JY, Burnett JR, Barrett PH, Rapp SR, Napawan N, Keller BT. Inhibition of the apical sodium-dependent bile acid transporter reduces LDL cholesterol and apoB by enhanced plasma clearance of LDL apoB. Arterioscler Thromb Vasc Biol. 2002 Nov 01; 22(11):1884-91. PMID: 12426220.
      Citations:    
    149. Brenes GA, Rapp SR, Rejeski WJ, Miller ME. Do optimism and pessimism predict physical functioning? J Behav Med. 2002 Jun; 25(3):219-31. PMID: 12055774.
      Citations:    
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