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Connection

Gregory Kucera to Drug Design

This is a "connection" page, showing publications Gregory Kucera has written about Drug Design.
Connection Strength

0.356
  1. Pickard AJ, Liu F, Bartenstein TF, Haines LG, Levine KE, Kucera GL, Bierbach U. Redesigning the DNA-targeted chromophore in platinum-acridine anticancer agents: a structure-activity relationship study. Chemistry. 2014 Dec 01; 20(49):16174-87.
    View in: PubMed
    Score: 0.121
  2. Ding S, Qiao X, Kucera GL, Bierbach U. Design of a platinum-acridine-endoxifen conjugate targeted at hormone-dependent breast cancer. Chem Commun (Camb). 2013 Mar 25; 49(24):2415-7.
    View in: PubMed
    Score: 0.109
  3. Ding S, Pickard AJ, Kucera GL, Bierbach U. Design of enzymatically cleavable prodrugs of a potent platinum-containing anticancer agent. Chemistry. 2014 Dec 01; 20(49):16164-73.
    View in: PubMed
    Score: 0.030
  4. Ding S, Qiao X, Kucera GL, Bierbach U. Using a build-and-click approach for producing structural and functional diversity in DNA-targeted hybrid anticancer agents. J Med Chem. 2012 Nov 26; 55(22):10198-203.
    View in: PubMed
    Score: 0.026
  5. Ma Z, Choudhury JR, Wright MW, Day CS, Saluta G, Kucera GL, Bierbach U. A non-cross-linking platinum-acridine agent with potent activity in non-small-cell lung cancer. J Med Chem. 2008 Dec 11; 51(23):7574-80.
    View in: PubMed
    Score: 0.020
  6. Ma Z, Saluta G, Kucera GL, Bierbach U. Effect of linkage geometry on biological activity in thiourea- and guanidine-substituted acridines and platinum-acridines. Bioorg Med Chem Lett. 2008 Jul 01; 18(13):3799-801.
    View in: PubMed
    Score: 0.019
  7. Guddneppanavar R, Saluta G, Kucera GL, Bierbach U. Synthesis, biological activity, and DNA-damage profile of platinum-threading intercalator conjugates designed to target adenine. J Med Chem. 2006 Jun 01; 49(11):3204-14.
    View in: PubMed
    Score: 0.017
  8. Barry CG, Turney EC, Day CS, Saluta G, Kucera GL, Bierbach U. Thermally inert metal ammines as light-inducible DNA-targeted agents. Synthesis, photochemistry, and photobiology of a prototypical rhodium(III)-intercalator conjugate. Inorg Chem. 2002 Dec 30; 41(26):7159-69.
    View in: PubMed
    Score: 0.013
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.