Gregory Kucera to Drug Design
This is a "connection" page, showing publications Gregory Kucera has written about Drug Design.
Connection Strength
0.354
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Pickard AJ, Liu F, Bartenstein TF, Haines LG, Levine KE, Kucera GL, Bierbach U. Redesigning the DNA-targeted chromophore in platinum-acridine anticancer agents: a structure-activity relationship study. Chemistry. 2014 Dec 01; 20(49):16174-87.
Score: 0.120
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Ding S, Qiao X, Kucera GL, Bierbach U. Design of a platinum-acridine-endoxifen conjugate targeted at hormone-dependent breast cancer. Chem Commun (Camb). 2013 Mar 25; 49(24):2415-7.
Score: 0.108
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Ding S, Pickard AJ, Kucera GL, Bierbach U. Design of enzymatically cleavable prodrugs of a potent platinum-containing anticancer agent. Chemistry. 2014 Dec 01; 20(49):16164-73.
Score: 0.030
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Ding S, Qiao X, Kucera GL, Bierbach U. Using a build-and-click approach for producing structural and functional diversity in DNA-targeted hybrid anticancer agents. J Med Chem. 2012 Nov 26; 55(22):10198-203.
Score: 0.026
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Ma Z, Choudhury JR, Wright MW, Day CS, Saluta G, Kucera GL, Bierbach U. A non-cross-linking platinum-acridine agent with potent activity in non-small-cell lung cancer. J Med Chem. 2008 Dec 11; 51(23):7574-80.
Score: 0.020
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Ma Z, Saluta G, Kucera GL, Bierbach U. Effect of linkage geometry on biological activity in thiourea- and guanidine-substituted acridines and platinum-acridines. Bioorg Med Chem Lett. 2008 Jul 01; 18(13):3799-801.
Score: 0.019
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Guddneppanavar R, Saluta G, Kucera GL, Bierbach U. Synthesis, biological activity, and DNA-damage profile of platinum-threading intercalator conjugates designed to target adenine. J Med Chem. 2006 Jun 01; 49(11):3204-14.
Score: 0.017
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Barry CG, Turney EC, Day CS, Saluta G, Kucera GL, Bierbach U. Thermally inert metal ammines as light-inducible DNA-targeted agents. Synthesis, photochemistry, and photobiology of a prototypical rhodium(III)-intercalator conjugate. Inorg Chem. 2002 Dec 30; 41(26):7159-69.
Score: 0.013