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James Eisenach to Animals

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This is a "connection" page, showing publications James Eisenach has written about Animals.
James Eisenach
Connection Strength
4.077
Animals
  1. Eisenach JC, Rice ASC. Improving Preclinical Development of Novel Interventions to Treat Pain: Insanity Is Doing the Same Thing Over and Over and Expecting Different Results. Anesth Analg. 2022 Dec 01; 135(6):1128-1136.
    View in: PubMed
    Score: 0.096
  2. Boada MD, Gutierrez S, Eisenach JC. Peripheral oxytocin restores light touch and nociceptor sensory afferents towards normal after nerve injury. Pain. 2019 05; 160(5):1146-1155.
    View in: PubMed
    Score: 0.075
  3. Eisenach JC, Yaksh TL. Spinal Exparel®-an extended duration of preclinical study needed. Br J Anaesth. 2019 03; 122(3):298-300.
    View in: PubMed
    Score: 0.073
  4. Street LM, Harris L, Curry RS, Eisenach JC. Capsaicin-induced pain and sensitisation in the postpartum period. Br J Anaesth. 2019 Jan; 122(1):103-110.
    View in: PubMed
    Score: 0.073
  5. Severino AL, Chen R, Hayashida K, Aschenbrenner CA, Sun H, Peters CM, Gutierrez S, Pan B, Eisenach JC. Plasticity and Function of Spinal Oxytocin and Vasopressin Signaling during Recovery from Surgery with Nerve Injury. Anesthesiology. 2018 09; 129(3):544-556.
    View in: PubMed
    Score: 0.072
  6. Hayashida KI, Kimuram M, Eisenach JC. Blockade of a2-adrenergic or metabotropic glutamate receptors induces glutamate release in the locus coeruleus to activate descending inhibition in rats with chronic neuropathic hypersensitivity. Neurosci Lett. 2018 05 29; 676:41-45.
    View in: PubMed
    Score: 0.070
  7. Hayashida KI, Eisenach JC. Descending Noradrenergic Inhibition: An Important Mechanism of Gabapentin Analgesia in Neuropathic Pain. Adv Exp Med Biol. 2018; 1099:93-100.
    View in: PubMed
    Score: 0.068
  8. Martin TJ, Strassburg TJ, Grigg AL, Kim SA, Ririe DG, Eisenach JC. Assessment of Behavioral Disruption in Rats with Abdominal Inflammation Using Visual Cue Titration and the Five-choice Serial-reaction Time Task. Anesthesiology. 2017 08; 127(2):372-381.
    View in: PubMed
    Score: 0.067
  9. Boada MD, Ririe DG, Eisenach JC. Post-discharge hyperpolarization is an endogenous modulatory factor limiting input from fast-conducting nociceptors (AHTMRs). Mol Pain. 2017 Jan-Dec; 13:1744806917726255.
    View in: PubMed
    Score: 0.064
  10. Eisenach JC, Warner DS, Houle TT. Reporting of Preclinical Research in Anesthesiology: Transparency and Enforcement. Anesthesiology. 2016 Apr; 124(4):763-5.
    View in: PubMed
    Score: 0.061
  11. Peters CM, Hayashida K, Suto T, Houle TT, Aschenbrenner CA, Martin TJ, Eisenach JC. Individual differences in acute pain-induced endogenous analgesia predict time to resolution of postoperative pain in the rat. Anesthesiology. 2015 Apr; 122(4):895-907.
    View in: PubMed
    Score: 0.057
  12. Martin TJ, Grigg A, Kim SA, Ririe DG, Eisenach JC. Assessment of attention threshold in rats by titration of visual cue duration during the five choice serial reaction time task. J Neurosci Methods. 2015 Feb 15; 241:37-43.
    View in: PubMed
    Score: 0.055
  13. Aschenbrenner CA, Houle TT, Gutierrez S, Eisenach JC. Modeling individual recovery after peripheral nerve injury in rats and the effects of parturition. Anesthesiology. 2014 Nov; 121(5):1056-67.
    View in: PubMed
    Score: 0.055
  14. Boada MD, Gutierrez S, Aschenbrenner CA, Houle TT, Hayashida K, Ririe DG, Eisenach JC. Nerve injury induces a new profile of tactile and mechanical nociceptor input from undamaged peripheral afferents. J Neurophysiol. 2015 Jan 01; 113(1):100-9.
    View in: PubMed
    Score: 0.055
  15. Peters CM, Ririe D, Houle TT, Aschenbrenner CA, Eisenach JC. Nociceptor-selective peripheral nerve block induces delayed mechanical hypersensitivity and neurotoxicity in rats. Anesthesiology. 2014 Apr; 120(4):976-86.
    View in: PubMed
    Score: 0.053
  16. Yaksh TL, Hobo S, Peters C, Osborn KG, Richter PJ, Rossi SS, Grafe MR, Eisenach JC. Preclinical toxicity screening of intrathecal oxytocin in rats and dogs. Anesthesiology. 2014 Apr; 120(4):951-61.
    View in: PubMed
    Score: 0.053
  17. Gutierrez S, Liu B, Hayashida K, Houle TT, Eisenach JC. Reversal of peripheral nerve injury-induced hypersensitivity in the postpartum period: role of spinal oxytocin. Anesthesiology. 2013 Jan; 118(1):152-9.
    View in: PubMed
    Score: 0.048
  18. Gutierrez S, Hayashida K, Eisenach JC. The puerperium alters spinal cord plasticity following peripheral nerve injury. Neuroscience. 2013 Jan 03; 228:301-8.
    View in: PubMed
    Score: 0.048
  19. Hayashida K, Kimura M, Yoshizumi M, Hobo S, Obata H, Eisenach JC. Ondansetron reverses antihypersensitivity from clonidine in rats after peripheral nerve injury: role of ?-aminobutyric acid in a2-adrenoceptor and 5-HT3 serotonin receptor analgesia. Anesthesiology. 2012 Aug; 117(2):389-98.
    View in: PubMed
    Score: 0.047
  20. Hayashida K, Peters CM, Gutierrez S, Eisenach JC. Depletion of endogenous noradrenaline does not prevent spinal cord plasticity following peripheral nerve injury. J Pain. 2012 Jan; 13(1):49-57.
    View in: PubMed
    Score: 0.045
  21. Hobo S, Hayashida K, Eisenach JC. Oxytocin inhibits the membrane depolarization-induced increase in intracellular calcium in capsaicin sensitive sensory neurons: a peripheral mechanism of analgesic action. Anesth Analg. 2012 Feb; 114(2):442-9.
    View in: PubMed
    Score: 0.045
  22. Hayashida K, Eisenach JC. A tropomyosine receptor kinase inhibitor blocks spinal neuroplasticity essential for the anti-hypersensitivity effects of gabapentin and clonidine in rats with peripheral nerve injury. J Pain. 2011 Jan; 12(1):94-100.
    View in: PubMed
    Score: 0.042
  23. Hayashida K, Eisenach JC. Spinal alpha 2-adrenoceptor-mediated analgesia in neuropathic pain reflects brain-derived nerve growth factor and changes in spinal cholinergic neuronal function. Anesthesiology. 2010 Aug; 113(2):406-12.
    View in: PubMed
    Score: 0.041
  24. Peters CM, Hayashida K, Ewan EE, Nakajima K, Obata H, Xu Q, Yaksh TL, Eisenach JC. Lack of analgesic efficacy of spinal ondansetron on thermal and mechanical hypersensitivity following spinal nerve ligation in the rat. Brain Res. 2010 Sep 17; 1352:83-93.
    View in: PubMed
    Score: 0.041
  25. Peters CM, Eisenach JC. Contribution of the chemokine (C-C motif) ligand 2 (CCL2) to mechanical hypersensitivity after surgical incision in rats. Anesthesiology. 2010 May; 112(5):1250-8.
    View in: PubMed
    Score: 0.040
  26. Hayashida K, Parker RA, Eisenach JC. Activation of glutamate transporters in the locus coeruleus paradoxically activates descending inhibition in rats. Brain Res. 2010 Mar 04; 1317:80-6.
    View in: PubMed
    Score: 0.039
  27. Hayashida K, Obata H, Nakajima K, Eisenach JC. Gabapentin acts within the locus coeruleus to alleviate neuropathic pain. Anesthesiology. 2008 Dec; 109(6):1077-84.
    View in: PubMed
    Score: 0.036
  28. Hayashida K, Eisenach JC. Multiplicative interactions to enhance gabapentin to treat neuropathic pain. Eur J Pharmacol. 2008 Nov 19; 598(1-3):21-6.
    View in: PubMed
    Score: 0.036
  29. Ririe DG, Liu B, Clayton B, Tong C, Eisenach JC. Electrophysiologic characteristics of large neurons in dorsal root ganglia during development and after hind paw incision in the rat. Anesthesiology. 2008 Jul; 109(1):111-7.
    View in: PubMed
    Score: 0.035
  30. Tong C, Conklin DR, Liu B, Ririe DG, Eisenach JC. Assessment of behavior during labor in rats and effect of intrathecal morphine. Anesthesiology. 2008 Jun; 108(6):1081-6.
    View in: PubMed
    Score: 0.035
  31. Liu B, Tong C, Eisenach JC. Pregnancy increases excitability of mechanosensitive afferents innervating the uterine cervix. Anesthesiology. 2008 Jun; 108(6):1087-92.
    View in: PubMed
    Score: 0.035
  32. Yaksh TL, Tozier N, Horais KA, Malkmus S, Rathbun M, Lafranco L, Eisenach J. Toxicology profile of N-methyl-D-aspartate antagonists delivered by intrathecal infusion in the canine model. Anesthesiology. 2008 May; 108(5):938-49.
    View in: PubMed
    Score: 0.035
  33. Hayashida KI, Clayton BA, Johnson JE, Eisenach JC. Brain derived nerve growth factor induces spinal noradrenergic fiber sprouting and enhances clonidine analgesia following nerve injury in rats. Pain. 2008 Jun; 136(3):348-355.
    View in: PubMed
    Score: 0.033
  34. Hayashida K, Parker R, Eisenach JC. Oral gabapentin activates spinal cholinergic circuits to reduce hypersensitivity after peripheral nerve injury and interacts synergistically with oral donepezil. Anesthesiology. 2007 Jun; 106(6):1213-9.
    View in: PubMed
    Score: 0.033
  35. Clayton BA, Hayashida K, Childers SR, Xiao R, Eisenach JC. Oral donepezil reduces hypersensitivity after nerve injury by a spinal muscarinic receptor mechanism. Anesthesiology. 2007 May; 106(5):1019-25.
    View in: PubMed
    Score: 0.033
  36. Romero-Sandoval A, Eisenach JC. Spinal cannabinoid receptor type 2 activation reduces hypersensitivity and spinal cord glial activation after paw incision. Anesthesiology. 2007 Apr; 106(4):787-94.
    View in: PubMed
    Score: 0.033
  37. Hayashida K, DeGoes S, Curry R, Eisenach JC. Gabapentin activates spinal noradrenergic activity in rats and humans and reduces hypersensitivity after surgery. Anesthesiology. 2007 Mar; 106(3):557-62.
    View in: PubMed
    Score: 0.032
  38. Martin TJ, Kim SA, Buechler NL, Porreca F, Eisenach JC. Opioid self-administration in the nerve-injured rat: relevance of antiallodynic effects to drug consumption and effects of intrathecal analgesics. Anesthesiology. 2007 Feb; 106(2):312-22.
    View in: PubMed
    Score: 0.032
  39. Romero-Sandoval A, Bynum T, Eisenach JC. Analgesia induced by perineural clonidine is enhanced in persistent neuritis. Neuroreport. 2007 Jan 08; 18(1):67-71.
    View in: PubMed
    Score: 0.032
  40. Ma W, Eisenach JC. Neuronal nitric oxide synthase is upregulated in a subset of primary sensory afferents after nerve injury which are necessary for analgesia from alpha2-adrenoceptor stimulation. Brain Res. 2007 Jan 05; 1127(1):52-8.
    View in: PubMed
    Score: 0.032
  41. Tong C, Conklin D, Eisenach JC. A pain model after gynecologic surgery: the effect of intrathecal and systemic morphine. Anesth Analg. 2006 Nov; 103(5):1288-93.
    View in: PubMed
    Score: 0.032
  42. Romero-Sandoval A, Eisenach JC. Clonidine reduces hypersensitivity and alters the balance of pro- and anti-inflammatory leukocytes after local injection at the site of inflammatory neuritis. Brain Behav Immun. 2007 Jul; 21(5):569-80.
    View in: PubMed
    Score: 0.032
  43. Martin TJ, Buechler NL, Eisenach JC. Intrathecal administration of a cylcooxygenase-1, but not a cyclooxygenase-2 inhibitor, reverses the effects of laparotomy on exploratory activity in rats. Anesth Analg. 2006 Sep; 103(3):690-5.
    View in: PubMed
    Score: 0.031
  44. Liu B, Eisenach JC. Perineural clonidine reduces p38 mitogen-activated protein kinase activation in sensory neurons. Neuroreport. 2006 Aug 21; 17(12):1313-7.
    View in: PubMed
    Score: 0.031
  45. Martin TJ, Kim SA, Eisenach JC. Clonidine maintains intrathecal self-administration in rats following spinal nerve ligation. Pain. 2006 Dec 05; 125(3):257-263.
    View in: PubMed
    Score: 0.031
  46. Zhu X, Vincler MA, Parker R, Eisenach JC. Spinal cord dynorphin expression increases, but does not drive microglial prostaglandin production or mechanical hypersensitivity after incisional surgery in rats. Pain. 2006 Nov; 125(1-2):43-52.
    View in: PubMed
    Score: 0.031
  47. Tong C, Conklin D, Clyne BB, Stanislaus JD, Eisenach JC. Uterine cervical afferents in thoracolumbar dorsal root ganglia express transient receptor potential vanilloid type 1 channel and calcitonin gene-related peptide, but not P2X3 receptor and somatostatin. Anesthesiology. 2006 Apr; 104(4):651-7.
    View in: PubMed
    Score: 0.030
  48. Ririe DG, Prout HD, Barclay D, Tong C, Lin M, Eisenach JC. Developmental differences in spinal cyclooxygenase 1 expression after surgical incision. Anesthesiology. 2006 Mar; 104(3):426-31.
    View in: PubMed
    Score: 0.030
  49. Eisenach JC. Treating and preventing chronic pain: a view from the spinal cord--Bonica Lecture, ASRA Annual Meeting, 2005. Reg Anesth Pain Med. 2006 Mar-Apr; 31(2):146-51.
    View in: PubMed
    Score: 0.030
  50. Ririe DG, Eisenach JC. Age-dependent responses to nerve injury-induced mechanical allodynia. Anesthesiology. 2006 Feb; 104(2):344-50.
    View in: PubMed
    Score: 0.030
  51. Romero-Sandoval A, Eisenach JC. Perineural clonidine reduces mechanical hypersensitivity and cytokine production in established nerve injury. Anesthesiology. 2006 Feb; 104(2):351-5.
    View in: PubMed
    Score: 0.030
  52. Liu B, Eisenach JC. Hyperexcitability of axotomized and neighboring unaxotomized sensory neurons is reduced days after perineural clonidine at the site of injury. J Neurophysiol. 2005 Nov; 94(5):3159-67.
    View in: PubMed
    Score: 0.029
  53. Li X, Eisenach JC. Adenosine reduces glutamate release in rat spinal synaptosomes. Anesthesiology. 2005 Nov; 103(5):1060-5.
    View in: PubMed
    Score: 0.029
  54. Romero-Sandoval EA, McCall C, Eisenach JC. Alpha2-adrenoceptor stimulation transforms immune responses in neuritis and blocks neuritis-induced pain. J Neurosci. 2005 Sep 28; 25(39):8988-94.
    View in: PubMed
    Score: 0.029
  55. Martin TJ, Kahn WR, Eisenach JC. Abdominal surgery decreases food-reinforced operant responding in rats: relevance of incisional pain. Anesthesiology. 2005 Sep; 103(3):629-37.
    View in: PubMed
    Score: 0.029
  56. Childers SR, Li X, Xiao R, Eisenach JC. Allosteric modulation of adenosine A1 receptor coupling to G-proteins in brain. J Neurochem. 2005 May; 93(3):715-23.
    View in: PubMed
    Score: 0.028
  57. Zhu X, Conklin DR, Eisenach JC. Preoperative inhibition of cyclooxygenase-1 in the spinal cord reduces postoperative pain. Anesth Analg. 2005 May; 100(5):1390-3, table of contents.
    View in: PubMed
    Score: 0.028
  58. Dalle C, Eisenach JC. Peripheral block of the hyperpolarization-activated cation current (Ih) reduces mechanical allodynia in animal models of postoperative and neuropathic pain. Reg Anesth Pain Med. 2005 May-Jun; 30(3):243-8.
    View in: PubMed
    Score: 0.028
  59. Obata H, Li X, Eisenach JC. alpha2-Adrenoceptor activation by clonidine enhances stimulation-evoked acetylcholine release from spinal cord tissue after nerve ligation in rats. Anesthesiology. 2005 Mar; 102(3):657-62.
    View in: PubMed
    Score: 0.028
  60. Obata H, Conklin D, Eisenach JC. Spinal noradrenaline transporter inhibition by reboxetine and Xen2174 reduces tactile hypersensitivity after surgery in rats. Pain. 2005 Feb; 113(3):271-276.
    View in: PubMed
    Score: 0.028
  61. Martin TJ, Zhang Y, Buechler N, Conklin DR, Eisenach JC. Intrathecal morphine and ketorolac analgesia after surgery: comparison of spontaneous and elicited responses in rats. Pain. 2005 Feb; 113(3):376-385.
    View in: PubMed
    Score: 0.028
  62. Ma W, Zhang Y, Bantel C, Eisenach JC. Medium and large injured dorsal root ganglion cells increase TRPV-1, accompanied by increased alpha2C-adrenoceptor co-expression and functional inhibition by clonidine. Pain. 2005 Feb; 113(3):386-394.
    View in: PubMed
    Score: 0.028
  63. Zhang Y, Conklin DR, Li X, Eisenach JC. Intrathecal morphine reduces allodynia after peripheral nerve injury in rats via activation of a spinal A1 adenosine receptor. Anesthesiology. 2005 Feb; 102(2):416-20.
    View in: PubMed
    Score: 0.028
  64. Vincler MA, Eisenach JC. Knock down of the alpha 5 nicotinic acetylcholine receptor in spinal nerve-ligated rats alleviates mechanical allodynia. Pharmacol Biochem Behav. 2005 Jan; 80(1):135-43.
    View in: PubMed
    Score: 0.028
  65. Ririe DG, Prout HM, Eisenach JC. Effect of cyclooxygenase-1 inhibition in postoperative pain is developmentally regulated. Anesthesiology. 2004 Oct; 101(4):1031-5.
    View in: PubMed
    Score: 0.027
  66. Martin TJ, Buechler NL, Kahn W, Crews JC, Eisenach JC. Effects of laparotomy on spontaneous exploratory activity and conditioned operant responding in the rat: a model for postoperative pain. Anesthesiology. 2004 Jul; 101(1):191-203.
    View in: PubMed
    Score: 0.027
  67. Ririe DG, Barclay D, Prout H, Tong C, Tobin JR, Eisenach JC. Preoperative sciatic nerve block decreases mechanical allodynia more in young rats: is preemptive analgesia developmentally modulated? Anesth Analg. 2004 Jul; 99(1):140-5.
    View in: PubMed
    Score: 0.027
  68. Yaksh TL, Horais KA, Tozier N, Rathbun M, Richter P, Rossi S, Grafe M, Tong C, Meschter C, Cline JM, Eisenach J. Intrathecal ketorolac in dogs and rats. Toxicol Sci. 2004 Aug; 80(2):322-34.
    View in: PubMed
    Score: 0.027
  69. Obata H, Li X, Eisenach JC. Spinal adenosine receptor activation reduces hypersensitivity after surgery by a different mechanism than after nerve injury. Anesthesiology. 2004 May; 100(5):1258-62.
    View in: PubMed
    Score: 0.027
  70. Eisenach JC, Lindner MD. Did experimenter bias conceal the efficacy of spinal opioids in previous studies with the spinal nerve ligation model of neuropathic pain? Anesthesiology. 2004 Apr; 100(4):765-7.
    View in: PubMed
    Score: 0.026
  71. Li X, Bantel C, Conklin D, Childers SR, Eisenach JC. Repeated dosing with oral allosteric modulator of adenosine A1 receptor produces tolerance in rats with neuropathic pain. Anesthesiology. 2004 Apr; 100(4):956-61.
    View in: PubMed
    Score: 0.026
  72. Shin SW, Eisenach JC. Peripheral nerve injury sensitizes the response to visceral distension but not its inhibition by the antidepressant milnacipran. Anesthesiology. 2004 Mar; 100(3):671-5.
    View in: PubMed
    Score: 0.026
  73. Duflo F, Zhang Y, Eisenach JC. Electrical field stimulation to study inhibitory mechanisms in individual sensory neurons in culture. Anesthesiology. 2004 Mar; 100(3):740-3.
    View in: PubMed
    Score: 0.026
  74. Vincler M, Eisenach JC. Plasticity of spinal nicotinic acetylcholine receptors following spinal nerve ligation. Neurosci Res. 2004 Feb; 48(2):139-45.
    View in: PubMed
    Score: 0.026
  75. Zhu X, Eisenach JC. Cyclooxygenase-1 in the spinal cord is altered after peripheral nerve injury. Anesthesiology. 2003 Nov; 99(5):1175-9.
    View in: PubMed
    Score: 0.026
  76. Ma W, Hatzis C, Eisenach JC. Intrathecal injection of cAMP response element binding protein (CREB) antisense oligonucleotide attenuates tactile allodynia caused by partial sciatic nerve ligation. Brain Res. 2003 Oct 24; 988(1-2):97-104.
    View in: PubMed
    Score: 0.026
  77. Ma W, Eisenach JC. Four PGE2 EP receptors are up-regulated in injured nerve following partial sciatic nerve ligation. Exp Neurol. 2003 Oct; 183(2):581-92.
    View in: PubMed
    Score: 0.026
  78. Shin SW, Sandner-Kiesling A, Eisenach JC. Systemic, but not intrathecal ketorolac is antinociceptive to uterine cervical distension in rats. Pain. 2003 Sep; 105(1-2):109-14.
    View in: PubMed
    Score: 0.025
  79. Ririe DG, Vernon TL, Tobin JR, Eisenach JC. Age-dependent responses to thermal hyperalgesia and mechanical allodynia in a rat model of acute postoperative pain. Anesthesiology. 2003 Aug; 99(2):443-8.
    View in: PubMed
    Score: 0.025
  80. Paqueron X, Conklin D, Eisenach JC. Plasticity in action of intrathecal clonidine to mechanical but not thermal nociception after peripheral nerve injury. Anesthesiology. 2003 Jul; 99(1):199-204.
    View in: PubMed
    Score: 0.025
  81. Tong C, Ma W, Shin SW, James RL, Eisenach JC. Uterine cervical distension induces cFos expression in deep dorsal horn neurons of the rat spinal cord. Anesthesiology. 2003 Jul; 99(1):205-11.
    View in: PubMed
    Score: 0.025
  82. Zhu X, Conklin D, Eisenach JC. Cyclooxygenase-1 in the spinal cord plays an important role in postoperative pain. Pain. 2003 Jul; 104(1-2):15-23.
    View in: PubMed
    Score: 0.025
  83. Vincler MA, Eisenach JC. Immunocytochemical localization of the alpha3, alpha4, alpha5, alpha7, beta2, beta3 and beta4 nicotinic acetylcholine receptor subunits in the locus coeruleus of the rat. Brain Res. 2003 Jun 06; 974(1-2):25-36.
    View in: PubMed
    Score: 0.025
  84. Bantel C, Li X, Eisenach JC. Intraspinal adenosine induces spinal cord norepinephrine release in spinal nerve-ligated rats but not in normal or sham controls. Anesthesiology. 2003 Jun; 98(6):1461-6.
    View in: PubMed
    Score: 0.025
  85. Shin SW, Eisenach JC. Intrathecal morphine reduces the visceromotor response to acute uterine cervical distension in an estrogen-independent manner. Anesthesiology. 2003 Jun; 98(6):1467-71; discussion 6A.
    View in: PubMed
    Score: 0.025
  86. Kang YJ, Eisenach JC. Intrathecal clonidine reduces hypersensitivity after nerve injury by a mechanism involving spinal m4 muscarinic receptors. Anesth Analg. 2003 May; 96(5):1403-8, table of contents.
    View in: PubMed
    Score: 0.025
  87. Duflo F, Conklin D, Li X, Eisenach JC. Spinal adrenergic and cholinergic receptor interactions activated by clonidine in postincisional pain. Anesthesiology. 2003 May; 98(5):1237-42.
    View in: PubMed
    Score: 0.025
  88. Ma W, Eisenach JC. Chronic constriction injury of sciatic nerve induces the up-regulation of descending inhibitory noradrenergic innervation to the lumbar dorsal horn of mice. Brain Res. 2003 Apr 25; 970(1-2):110-8.
    View in: PubMed
    Score: 0.025
  89. Pancaro C, Ma W, Vincler M, Duflo F, Eisenach JC. Clonidine-induced neuronal activation in the spinal cord is altered after peripheral nerve injury. Anesthesiology. 2003 Mar; 98(3):748-53.
    View in: PubMed
    Score: 0.024
  90. Li X, Conklin D, Pan HL, Eisenach JC. Allosteric adenosine receptor modulation reduces hypersensitivity following peripheral inflammation by a central mechanism. J Pharmacol Exp Ther. 2003 Jun; 305(3):950-5.
    View in: PubMed
    Score: 0.024
  91. Ma W, Du W, Eisenach JC. Intrathecal lidocaine reverses tactile allodynia caused by nerve injuries and potentiates the antiallodynic effect of the COX inhibitor ketorolac. Anesthesiology. 2003 Jan; 98(1):203-8.
    View in: PubMed
    Score: 0.024
  92. Conklin DR, Eisenach JC. Intrathecal ketorolac enhances antinociception from clonidine. Anesth Analg. 2003 Jan; 96(1):191-4, table of contents.
    View in: PubMed
    Score: 0.024
  93. Kang YJ, Vincler M, Li X, Conklin D, Eisenach JC. Intrathecal ketorolac reverses hypersensitivity following acute fentanyl exposure. Anesthesiology. 2002 Dec; 97(6):1641-4.
    View in: PubMed
    Score: 0.024
  94. Sandner-Kiesling A, Eisenach JC. Pharmacology of opioid inhibition to noxious uterine cervical distension. Anesthesiology. 2002 Oct; 97(4):966-71.
    View in: PubMed
    Score: 0.024
  95. Lavand'homme PM, Ma W, De Kock M, Eisenach JC. Perineural alpha(2A)-adrenoceptor activation inhibits spinal cord neuroplasticity and tactile allodynia after nerve injury. Anesthesiology. 2002 Oct; 97(4):972-80.
    View in: PubMed
    Score: 0.024
  96. Duflo F, Li X, Bantel C, Pancaro C, Vincler M, Eisenach JC. Peripheral nerve injury alters the alpha2 adrenoceptor subtype activated by clonidine for analgesia. Anesthesiology. 2002 Sep; 97(3):636-41.
    View in: PubMed
    Score: 0.024
  97. Zhu X, Li X, Eisenach JC. Spinal norepinephrine release from nitric oxide species is not increased following peripheral nerve injury in rats. Brain Res. 2002 Aug 30; 947(2):199-203.
    View in: PubMed
    Score: 0.024
  98. Bantel C, Childers SR, Eisenach JC. Role of adenosine receptors in spinal G-protein activation after peripheral nerve injury. Anesthesiology. 2002 Jun; 96(6):1443-9.
    View in: PubMed
    Score: 0.023
  99. Li X, Eisenach JC. Nicotinic acetylcholine receptor regulation of spinal norepinephrine release. Anesthesiology. 2002 Jun; 96(6):1450-6.
    View in: PubMed
    Score: 0.023
  100. Li X, Conklin D, Ma W, Zhu X, Eisenach JC. Spinal noradrenergic activation mediates allodynia reduction from an allosteric adenosine modulator in a rat model of neuropathic pain. Pain. 2002 May; 97(1-2):117-25.
    View in: PubMed
    Score: 0.023
  101. Ma W, Eisenach JC. Morphological and pharmacological evidence for the role of peripheral prostaglandins in the pathogenesis of neuropathic pain. Eur J Neurosci. 2002 Mar; 15(6):1037-47.
    View in: PubMed
    Score: 0.023
  102. Sandner-Kiesling A, Pan HL, Chen SR, James RL, DeHaven-Hudkins DL, Dewan DM, Eisenach JC. Effect of kappa opioid agonists on visceral nociception induced by uterine cervical distension in rats. Pain. 2002 Mar; 96(1-2):13-22.
    View in: PubMed
    Score: 0.023
  103. Sandner-Kiesling A, Eisenach JC. Estrogen reduces efficacy of mu- but Not kappa-opioid agonist inhibition in response to uterine cervical distension. Anesthesiology. 2002 Feb; 96(2):375-9.
    View in: PubMed
    Score: 0.023
  104. Bantel C, Tobin JR, Li X, Childers SR, Chen SR, Eisenach JC. Intrathecal adenosine following spinal nerve ligation in rat: short residence time in cerebrospinal fluid and no change in A(1) receptor binding. Anesthesiology. 2002 Jan; 96(1):103-8.
    View in: PubMed
    Score: 0.023
  105. Boada MD, Martin TJ, Parker R, Houle TT, Eisenach JC, Ririe DG. Recovery from nerve injury induced behavioral hypersensitivity in rats parallels resolution of abnormal primary sensory afferent signaling. Pain. 2020 05; 161(5):949-959.
    View in: PubMed
    Score: 0.020
  106. Boada MD, Ririe DG, Martin CW, Martin SJ, Kim SA, Eisenach JC, Martin TJ. Nociceptive input after peripheral nerve injury results in cognitive impairment and alterations in primary afferent physiology in rats. Pain. 2020 05; 161(5):960-969.
    View in: PubMed
    Score: 0.020
  107. Hayashida KI, Eisenach JC, Kawatani M, Martin TJ. Peripheral nerve injury in rats induces alternations in choice behavior associated with food reinforcement. J Physiol Sci. 2019 Sep; 69(5):769-777.
    View in: PubMed
    Score: 0.019
  108. Gutierrez S, Alvarado-Vázquez PA, Eisenach JC, Romero-Sandoval EA, Boada MD. Tachykinins modulate nociceptive responsiveness and sensitization: In vivo electrical characterization of primary sensory neurons in tachykinin knockout (Tac1 KO) mice. Mol Pain. 2019 Jan-Dec; 15:1744806919845750.
    View in: PubMed
    Score: 0.018
  109. Ririe DG, Boada MD, MacGregor MK, Martin SJ, Strassburg TJ, Kim SA, Eisenach JC, Martin TJ. Incisional Nociceptive Input Impairs Attention-related Behavior and Is Associated with Reduced Neuronal Activity in the Prefrontal Cortex in Rats. Anesthesiology. 2018 10; 129(4):778-790.
    View in: PubMed
    Score: 0.018
  110. Arora V, Martin TJ, Aschenbrenner CA, Hayashida K, Kim SA, Parker RA, Eisenach JC, Peters CM. Psychosocial Stress Delays Recovery of Postoperative Pain Following Incisional Surgery in the Rat. Neuroscience. 2018 07 01; 382:35-47.
    View in: PubMed
    Score: 0.017
  111. Kimura M, Eisenach JC, Hayashida KI. Gabapentin loses efficacy over time after nerve injury in rats: role of glutamate transporter-1 in the locus coeruleus. Pain. 2016 09; 157(9):2024-2032.
    View in: PubMed
    Score: 0.016
  112. Boada MD, Eisenach JC, Ririe DG. Mechanical sensibility of nociceptive and non-nociceptive fast-conducting afferents is modulated by skin temperature. J Neurophysiol. 2016 Jan 01; 115(1):546-53.
    View in: PubMed
    Score: 0.015
  113. Arora V, Morado-Urbina CE, Aschenbrenner CA, Hayashida K, Wang F, Martin TJ, Eisenach JC, Peters CM. Disruption of Spinal Noradrenergic Activation Delays Recovery of Acute Incision-Induced Hypersensitivity and Increases Spinal Glial Activation in the Rat. J Pain. 2016 Feb; 17(2):190-202.
    View in: PubMed
    Score: 0.015
  114. Kimura M, Suto T, Eisenach JC, Hayashida K. Down-regulation of astroglial glutamate transporter-1 in the locus coeruleus impairs pain-evoked endogenous analgesia in rats. Neurosci Lett. 2015 Nov 03; 608:18-22.
    View in: PubMed
    Score: 0.015
  115. Kimura M, Suto T, Morado-Urbina CE, Peters CM, Eisenach JC, Hayashida K. Impaired Pain-evoked Analgesia after Nerve Injury in Rats Reflects Altered Glutamate Regulation in the Locus Coeruleus. Anesthesiology. 2015 Oct; 123(4):899-908.
    View in: PubMed
    Score: 0.015
  116. Boada DM, Martin TJ, Peters CM, Hayashida K, Harris MH, Houle TT, Boyden ES, Eisenach JC, Ririe DG. Fast-conducting mechanoreceptors contribute to withdrawal behavior in normal and nerve injured rats. Pain. 2014 Dec; 155(12):2646-2655.
    View in: PubMed
    Score: 0.014
  117. Suto T, Eisenach JC, Hayashida K. Peripheral nerve injury and gabapentin, but not their combination, impair attentional behavior via direct effects on noradrenergic signaling in the brain. Pain. 2014 Oct; 155(10):1935-42.
    View in: PubMed
    Score: 0.013
  118. Suto T, Severino AL, Eisenach JC, Hayashida K. Gabapentin increases extracellular glutamatergic level in the locus coeruleus via astroglial glutamate transporter-dependent mechanisms. Neuropharmacology. 2014 Jun; 81:95-100.
    View in: PubMed
    Score: 0.013
  119. Yoshizumi M, Eisenach JC, Hayashida K. Valproate prevents dysregulation of spinal glutamate and reduces the development of hypersensitivity in rats after peripheral nerve injury. J Pain. 2013 Nov; 14(11):1485-91.
    View in: PubMed
    Score: 0.013
  120. Kimura M, Hayashida K, Eisenach JC, Saito S, Obata H. Relief of hypersensitivity after nerve injury from systemic donepezil involves spinal cholinergic and ?-aminobutyric acid mechanisms. Anesthesiology. 2013 Jan; 118(1):173-80.
    View in: PubMed
    Score: 0.012
  121. Boada MD, Gutierrez S, Giffear K, Eisenach JC, Ririe DG. Skin incision-induced receptive field responses of mechanosensitive peripheral neurons are developmentally regulated in the rat. J Neurophysiol. 2012 Aug; 108(4):1122-9.
    View in: PubMed
    Score: 0.012
  122. Yoshizumi M, Parker RA, Eisenach JC, Hayashida K. Gabapentin inhibits ?-amino butyric acid release in the locus coeruleus but not in the spinal dorsal horn after peripheral nerve injury in rats. Anesthesiology. 2012 Jun; 116(6):1347-53.
    View in: PubMed
    Score: 0.012
  123. Yoshizumi M, Eisenach JC, Hayashida K. Riluzole and gabapentinoids activate glutamate transporters to facilitate glutamate-induced glutamate release from cultured astrocytes. Eur J Pharmacol. 2012 Feb 29; 677(1-3):87-92.
    View in: PubMed
    Score: 0.011
  124. Hains LE, Loram LC, Taylor FR, Strand KA, Wieseler JL, Barrientos RM, Young JJ, Frank MG, Sobesky J, Martin TJ, Eisenach JC, Maier SF, Johnson JD, Fleshner M, Watkins LR. Prior laparotomy or corticosterone potentiates lipopolysaccharide-induced fever and sickness behaviors. J Neuroimmunol. 2011 Oct 28; 239(1-2):53-60.
    View in: PubMed
    Score: 0.011
  125. Boada MD, Gutierrez S, Houle T, Eisenach JC, Ririe DG. Developmental differences in peripheral glabrous skin mechanosensory nerve receptive field and intracellular electrophysiologic properties: phenotypic characterization in infant and juvenile rats. Int J Dev Neurosci. 2011 Dec; 29(8):847-54.
    View in: PubMed
    Score: 0.011
  126. Hobo S, Eisenach JC, Hayashida K. Up-regulation of spinal glutamate transporters contributes to anti-hypersensitive effects of valproate in rats after peripheral nerve injury. Neurosci Lett. 2011 Sep 08; 502(1):52-5.
    View in: PubMed
    Score: 0.011
  127. Boada MD, Houle TT, Eisenach JC, Ririe DG. Differing neurophysiologic mechanosensory input from glabrous and hairy skin in juvenile rats. J Neurophysiol. 2010 Dec; 104(6):3568-75.
    View in: PubMed
    Score: 0.010
  128. Hains LE, Loram LC, Weiseler JL, Frank MG, Bloss EB, Sholar P, Taylor FR, Harrison JA, Martin TJ, Eisenach JC, Maier SF, Watkins LR. Pain intensity and duration can be enhanced by prior challenge: initial evidence suggestive of a role of microglial priming. J Pain. 2010 Oct; 11(10):1004-14.
    View in: PubMed
    Score: 0.010
  129. Gurun MS, Parker R, Eisenach JC, Vincler M. The effect of peripherally administered CDP-choline in an acute inflammatory pain model: the role of alpha7 nicotinic acetylcholine receptor. Anesth Analg. 2009 May; 108(5):1680-7.
    View in: PubMed
    Score: 0.009
  130. Rice ASC, Cimino-Brown D, Eisenach JC, Kontinen VK, Lacroix-Fralish ML, Machin I, Mogil JS, Stöhr T. Animal models and the prediction of efficacy in clinical trials of analgesic drugs: a critical appraisal and call for uniform reporting standards. Pain. 2008 Oct 15; 139(2):243-247.
    View in: PubMed
    Score: 0.009
  131. Stone LS, Kitto KF, Eisenach JC, Fairbanks CA, Wilcox GL. ST91 [2-(2,6-diethylphenylamino)-2-imidazoline hydrochloride]-mediated spinal antinociception and synergy with opioids persists in the absence of functional alpha-2A- or alpha-2C-adrenergic receptors. J Pharmacol Exp Ther. 2007 Dec; 323(3):899-906.
    View in: PubMed
    Score: 0.008
  132. Yan T, Liu B, Du D, Eisenach JC, Tong C. Estrogen amplifies pain responses to uterine cervical distension in rats by altering transient receptor potential-1 function. Anesth Analg. 2007 May; 104(5):1246-50, tables of contents.
    View in: PubMed
    Score: 0.008
  133. Obata H, Eisenach JC, Hussain H, Bynum T, Vincler M. Spinal glial activation contributes to postoperative mechanical hypersensitivity in the rat. J Pain. 2006 Nov; 7(11):816-22.
    View in: PubMed
    Score: 0.008
  134. Martin TJ, Eisenach JC, Misler J, Childers SR. Chronic activation of spinal adenosine A1 receptors results in hypersensitivity. Neuroreport. 2006 Oct 23; 17(15):1619-22.
    View in: PubMed
    Score: 0.008
  135. Liu B, Eisenach JC, Tong C. Chronic estrogen sensitizes a subset of mechanosensitive afferents innervating the uterine cervix. J Neurophysiol. 2005 Apr; 93(4):2167-73.
    View in: PubMed
    Score: 0.007
  136. Bantel C, Eisenach JC, Duflo F, Tobin JR, Childers SR. Spinal nerve ligation increases alpha2-adrenergic receptor G-protein coupling in the spinal cord. Brain Res. 2005 Mar 15; 1038(1):76-82.
    View in: PubMed
    Score: 0.007
  137. Du D, Eisenach JC, Ririe DG, Tong C. The antinociceptive effects of spinal cyclooxygenase inhibitors on uterine cervical distension. Brain Res. 2004 Oct 22; 1024(1-2):130-6.
    View in: PubMed
    Score: 0.007
  138. Shin SW, Eisenach JC, Rao SG, Tong C. The monoamine reuptake inhibitor milnacipran does not affect nociception to acute visceral distension in rats. Anesth Analg. 2004 May; 98(5):1365-9, table of contents.
    View in: PubMed
    Score: 0.007
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.