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Walter T. Ambrosius PhD

TitleProfessor
InstitutionWake Forest School of Medicine
DepartmentPHS-Biostatistics and Data Science (Public Health Sciences)
Address
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    Other Positions
    TitleProfessor
    InstitutionWake Forest School of Medicine
    DepartmentClinical and Translational Science Institute

    TitleChair
    InstitutionWake Forest School of Medicine
    DepartmentPHS-Biostatistics and Data Science (Public Health Sciences)


    Collapse Research 
    Collapse research activities and funding
    U01AG050499     (PAHOR, MARCO)Sep 1, 2015 - May 31, 2021
    NIH
    The ENRGISE Study
    Role: Co-Principal Investigator
    U24HL141732     (AMBROSIUS, WALTER T)Jun 10, 2019 - May 31, 2025
    NIH
    2/2 PROmote weight loss in obese PAD patients to preVEnt mobility loss: The PROVE Trial--DCC
    Role: Principal Investigator
    U19AG065188     (ALEXANDER, KAREN P)Sep 30, 2019 - Aug 31, 2026
    NIH
    PRagmatic EValuation of evENTs And Benefits of Lipid-lowering in oldEr Adults (PREVENTABLE)
    Role: Co-Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Garimella PS, Lee AK, Ambrosius WT, Bhatt U, Cheung AK, Chonchol M, Craven T, Hawfield AT, Jotwani V, Killeen A, Punzi H, Sarnak MJ, Wall BM, Ix JH, Shlipak MG. Markers of kidney tubule function and risk of cardiovascular disease events and mortality in the SPRINT trial. Eur Heart J. 2019 11 01; 40(42):3486-3493. PMID: 31257404.
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    2. Pahor M, Anton SD, Beavers DP, Cauley JA, Fielding RA, Kritchevsky SB, Leeuwenburgh C, Lewis KH, Liu CK, Lovato LC, Lu J, Manini TM, McDermott MM, Miller ME, Newman AB, Radziszewska B, Stowe CL, Tracy RP, Walkup MP, Wu SS, Ambrosius WT. Effect of Losartan and Fish Oil on Plasma IL-6 and Mobility in Older Persons. The ENRGISE Pilot Randomized Clinical Trial. J Gerontol A Biol Sci Med Sci. 2019 09 15; 74(10):1612-1619. PMID: 30541065.
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    3. Lee AK, Katz R, Jotwani V, Garimella PS, Ambrosius WT, Cheung AK, Gren LH, Neyra JA, Punzi H, Raphael KL, Shlipak MG, Ix JH. Distinct Dimensions of Kidney Health and Risk of Cardiovascular Disease, Heart Failure, and Mortality. Hypertension. 2019 10; 74(4):872-879. PMID: 31378102.
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    4. Cauley JA, Manini TM, Lovato L, Talton J, Anton SD, Domanchuk K, Kennedy K, Stowe CL, Walkup M, Fielding RA, Kritchevsky SB, McDermott MM, Newman AB, Ambrosius WT, Pahor M. The Enabling Reduction of Low-Grade Inflammation in Seniors (ENRGISE) Pilot Study: Screening Methods and Recruitment Results. J Gerontol A Biol Sci Med Sci. 2019 07 12; 74(8):1296-1302. PMID: 30202946.
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    5. Nowak KL, Chonchol M, Jovanovich A, You Z, Bates J, Foy C, Glasser S, Killeen AA, Kostis J, Rodriguez CJ, Segal M, Simmons DL, Taylor A, Lovato LC, Ambrosius WT, Supiano MA. Serum Sodium and Pulse Pressure in SPRINT. Am J Hypertens. 2019 06 11; 32(7):649-656. PMID: 30977767.
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    6. Jotwani VK, Lee AK, Estrella MM, Katz R, Garimella PS, Malhotra R, Rifkin DE, Ambrosius W, Freedman BI, Cheung AK, Raphael KL, Drawz P, Neyra JA, Oparil S, Punzi H, Shlipak MG, Ix JH. Urinary Biomarkers of Tubular Damage Are Associated with Mortality but Not Cardiovascular Risk among Systolic Blood Pressure Intervention Trial Participants with Chronic Kidney Disease. Am J Nephrol. 2019; 49(5):346-355. PMID: 30939472.
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    7. Freedland KE, King AC, Ambrosius WT, Mayo-Wilson E, Mohr DC, Czajkowski SM, Thabane L, Collins LM, Rebok GW, Treweek SP, Cook TD, Edinger JD, Stoney CM, Campo RA, Young-Hyman D, Riley WT. The selection of comparators for randomized controlled trials of health-related behavioral interventions: recommendations of an NIH expert panel. J Clin Epidemiol. 2019 06; 110:74-81. PMID: 30826377.
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    8. Ginsberg C, Craven TE, Chonchol MB, Cheung AK, Sarnak MJ, Ambrosius WT, Killeen AA, Raphael KL, Bhatt UY, Chen J, Chertow GM, Freedman BI, Oparil S, Papademetriou V, Wall BM, Wright CB, Ix JH, Shlipak MG. PTH, FGF23, and Intensive Blood Pressure Lowering in Chronic Kidney Disease Participants in SPRINT. Clin J Am Soc Nephrol. 2018 12 07; 13(12):1816-1824. PMID: 30425104.
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    9. Malhotra R, Craven T, Ambrosius WT, Killeen AA, Haley WE, Cheung AK, Chonchol M, Sarnak M, Parikh CR, Shlipak MG, Ix JH. Effects of Intensive Blood Pressure Lowering on Kidney Tubule Injury in CKD: A Longitudinal Subgroup Analysis in SPRINT. Am J Kidney Dis. 2019 01; 73(1):21-30. PMID: 30291012.
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    10. Supiano MA, Lovato L, Ambrosius WT, Bates J, Beddhu S, Drawz P, Dwyer JP, Hamburg NM, Kitzman D, Lash J, Lustigova E, Miracle CM, Oparil S, Raj DS, Weiner DE, Taylor A, Vita JA, Yunis R, Chertow GM, Chonchol M. Pulse wave velocity and central aortic pressure in systolic blood pressure intervention trial participants. PLoS One. 2018; 13(9):e0203305. PMID: 30256784.
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    11. Beddhu S, Chertow GM, Greene T, Whelton PK, Ambrosius WT, Cheung AK, Cutler J, Fine L, Boucher R, Wei G, Zhang C, Kramer H, Bress AP, Kimmel PL, Oparil S, Lewis CE, Rahman M, Cushman WC. Effects of Intensive Systolic Blood Pressure Lowering on Cardiovascular Events and Mortality in Patients With Type 2 Diabetes Mellitus on Standard Glycemic Control and in Those Without Diabetes Mellitus: Reconciling Results From ACCORD BP and SPRINT. J Am Heart Assoc. 2018 09 18; 7(18):e009326. PMID: 30371182.
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    12. Beavers KM, Walkup MP, Weaver AA, Lenchik L, Kritchevsky SB, Nicklas BJ, Ambrosius WT, Stitzel JD, Register TC, Shapses SA, Marsh AP, Rejeski WJ. Effect of Exercise Modality During Weight Loss on Bone Health in Older Adults With Obesity and Cardiovascular Disease or Metabolic Syndrome: A Randomized Controlled Trial. J Bone Miner Res. 2018 12; 33(12):2140-2149. PMID: 30088288.
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    13. Shapiro BP, Ambrosius WT, Blackshear JL, Cushman WC, Whelton PK, Oparil S, Beddhu S, Dwyer JP, Gren LH, Kostis WJ, Lioudis M, Pisoni R, Rosendorff C, Haley WE. Impact of Intensive Versus Standard Blood Pressure Management by Tertiles of Blood Pressure in SPRINT (Systolic Blood Pressure Intervention Trial). Hypertension. 2018 06; 71(6):1064-1074. PMID: 29712745.
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    14. Yang S, Ambrosius WT, Fine LJ, Bress AP, Cushman WC, Raj DS, Rehman S, Tamariz L. A new modeling and inference approach for the Systolic Blood Pressure Intervention Trial outcomes. Clin Trials. 2018 06; 15(3):305-312. PMID: 29671345.
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    15. Soliman EZ, Ambrosius WT, Lewis CE. Response by Soliman et al to Letters Regarding Article, "Effect of Intensive Blood Pressure Lowering on Left Ventricular Hypertrophy in Patients With Hypertension: SPRINT (Systolic Blood Pressure Intervention Trial)". Circulation. 2018 03 20; 137(12):1300-1301. PMID: 29555717.
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    16. Chen H, Rejeski WJ, Gill TM, Guralnik J, King AC, Newman A, Blair SN, Conroy D, Liu C, Manini TM, Pahor M, Ambrosius WT, Miller ME. A Comparison of Self-report Indices of Major Mobility Disability to Failure on the 400-m Walk Test: The LIFE Study. J Gerontol A Biol Sci Med Sci. 2018 03 14; 73(4):513-518. PMID: 28958023.
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    17. Johnson KC, Whelton PK, Cushman WC, Cutler JA, Evans GW, Snyder JK, Ambrosius WT, Beddhu S, Cheung AK, Fine LJ, Lewis CE, Rahman M, Reboussin DM, Rocco MV, Oparil S, Wright JT. Blood Pressure Measurement in SPRINT (Systolic Blood Pressure Intervention Trial). Hypertension. 2018 05; 71(5):848-857. PMID: 29531173.
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    18. Gower EW, Lovato JF, Ambrosius WT, Chew EY, Danis RP, Davis MD, Goff DC, Greven CM. Lack of Longitudinal Association Between Thiazolidinediones and Incidence and Progression of Diabetic Eye Disease: The ACCORD Eye Study. Am J Ophthalmol. 2018 03; 187:138-147. PMID: 29275147.
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    19. Cochrane SK, Chen SH, Fitzgerald JD, Dodson JA, Fielding RA, King AC, McDermott MM, Manini TM, Marsh AP, Newman AB, Pahor M, Tudor-Locke C, Ambrosius WT, Buford TW. Association of Accelerometry-Measured Physical Activity and Cardiovascular Events in Mobility-Limited Older Adults: The LIFE (Lifestyle Interventions and Independence for Elders) Study. J Am Heart Assoc. 2017 Dec 02; 6(12). PMID: 29197830.
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    20. Fanning J, Walkup MP, Ambrosius WT, Brawley LR, Ip EH, Marsh AP, Rejeski WJ. Change in health-related quality of life and social cognitive outcomes in obese, older adults in a randomized controlled weight loss trial: Does physical activity behavior matter? J Behav Med. 2018 06; 41(3):299-308. PMID: 29168052.
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    21. Beavers KM, Ambrosius WT, Rejeski WJ, Burdette JH, Walkup MP, Sheedy JL, Nesbit BA, Gaukstern JE, Nicklas BJ, Marsh AP. Effect of Exercise Type During Intentional Weight Loss on Body Composition in Older Adults with Obesity. Obesity (Silver Spring). 2017 11; 25(11):1823-1829. PMID: 29086504.
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    22. Lee SJ, Heo SH, Ambrosius WT, Bushnell CD. Factors Mediating Outcome After Stroke: Gender, Thrombolysis, and Their Interaction. Transl Stroke Res. 2018 06; 9(3):267-273. PMID: 29067622.
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    23. Rejeski WJ, Ambrosius WT, Burdette JH, Walkup MP, Marsh AP. Community Weight Loss to Combat Obesity and Disability in At-Risk Older Adults. J Gerontol A Biol Sci Med Sci. 2017 Oct 12; 72(11):1547-1553. PMID: 28064148.
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    24. Chen H, Ambrosius WT, Murphy TE, Fielding R, Pahor M, Santanasto A, Tudor-Locke C, Jack Rejeski W, Miller ME. Imputation of Gait Speed for Noncompleters in the 400-Meter Walk: Application to the Lifestyle Interventions for Elders Study. J Am Geriatr Soc. 2017 Dec; 65(12):2566-2571. PMID: 28884789.
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    25. Manini TM, Anton SD, Beavers DP, Cauley JA, Espeland MA, Fielding RA, Kritchevsky SB, Leeuwenburgh C, Lewis KH, Liu C, McDermott MM, Miller ME, Tracy RP, Walston JD, Radziszewska B, Lu J, Stowe C, Wu S, Newman AB, Ambrosius WT, Pahor M. ENabling Reduction of Low-grade Inflammation in SEniors Pilot Study: Concept, Rationale, and Design. J Am Geriatr Soc. 2017 Sep; 65(9):1961-1968. PMID: 28734043.
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    26. Wanigatunga AA, Ambrosius WT, Rejeski WJ, Gill TM, Glynn NW, Tudor-Locke C, Manini TM. Association Between Structured Physical Activity and Sedentary Time in Older Adults. JAMA. 2017 Jul 18; 318(3):297-299. PMID: 28719683.
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    27. Duncan PW, Bushnell CD, Rosamond WD, Jones Berkeley SB, Gesell SB, D'Agostino RB, Ambrosius WT, Barton-Percival B, Bettger JP, Coleman SW, Cummings DM, Freburger JK, Halladay J, Johnson AM, Kucharska-Newton AM, Lundy-Lamm G, Lutz BJ, Mettam LH, Pastva AM, Sissine ME, Vetter B. The Comprehensive Post-Acute Stroke Services (COMPASS) study: design and methods for a cluster-randomized pragmatic trial. BMC Neurol. 2017 Jul 17; 17(1):133. PMID: 28716014.
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    28. Soliman EZ, Ambrosius WT, Cushman WC, Zhang ZM, Bates JT, Neyra JA, Carson TY, Tamariz L, Ghazi L, Cho ME, Shapiro BP, He J, Fine LJ, Lewis CE. Effect of Intensive Blood Pressure Lowering on Left Ventricular Hypertrophy in Patients With Hypertension: SPRINT (Systolic Blood Pressure Intervention Trial). Circulation. 2017 Aug 01; 136(5):440-450. PMID: 28512184.
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    29. Botoseneanu A, Chen H, Ambrosius WT, Allore HG, Anton S, Folta SC, King AC, Nicklas BJ, Spring BJ, Strotmeyer ES, Gill TM. Effect of Metabolic Syndrome on the Mobility Benefit of a Structured Physical Activity Intervention-The Lifestyle Interventions and Independence for Elders Randomized Clinical Trial. J Am Geriatr Soc. 2017 Jun; 65(6):1244-1250. PMID: 28369670.
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    30. Lewis CE, Johnson KC, Rahman M, Sink KM, Ambrosius WT. Let's Not SPRINT to Judgment About New Blood Pressure Goals. Ann Intern Med. 2016 12 20; 165(12):889. PMID: 27992902.
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    31. Newman AB, Dodson JA, Church TS, Buford TW, Fielding RA, Kritchevsky S, Beavers D, Pahor M, Stafford RS, Szady AD, Ambrosius WT, McDermott MM. Cardiovascular Events in a Physical Activity Intervention Compared With a Successful Aging Intervention: The LIFE Study Randomized Trial. JAMA Cardiol. 2016 Aug 01; 1(5):568-74. PMID: 27439082.
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    32. Wright JT, Williamson JD, Whelton PK, Snyder JK, Sink KM, Rocco MV, Reboussin DM, Rahman M, Oparil S, Lewis CE, Kimmel PL, Johnson KC, Goff DC, Fine LJ, Cutler JA, Cushman WC, Cheung AK, Ambrosius WT. A Randomized Trial of Intensive versus Standard Blood-Pressure Control. N Engl J Med. 2015 Nov 26; 373(22):2103-16. PMID: 26551272.
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    33. Siraj ES, Rubin DJ, Riddle MC, Miller ME, Hsu FC, Ismail-Beigi F, Chen SH, Ambrosius WT, Thomas A, Bestermann W, Buse JB, Genuth S, Joyce C, Kovacs CS, O'Connor PJ, Sigal RJ, Solomon S. Insulin Dose and Cardiovascular Mortality in the ACCORD Trial. Diabetes Care. 2015 Nov; 38(11):2000-8. PMID: 26464212.
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    34. Schwartz AV, Chen H, Ambrosius WT, Sood A, Josse RG, Bonds DE, Schnall AM, Vittinghoff E, Bauer DC, Banerji MA, Cohen RM, Hamilton BP, Isakova T, Sellmeyer DE, Simmons DL, Shibli-Rahhal A, Williamson JD, Margolis KL. Effects of TZD Use and Discontinuation on Fracture Rates in ACCORD Bone Study. J Clin Endocrinol Metab. 2015 Nov; 100(11):4059-66. PMID: 26305617.
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    35. Marsh AP, Janssen JA, Ip EH, Barnard RT, Ambrosius WT, Brubaker PR, Burdette JH, Sheedy JL, Rejeski WJ. Assessing Walking Activity in Older Adults: Development and Validation of a Novel Computer-Animated Assessment Tool. J Gerontol A Biol Sci Med Sci. 2015 Dec; 70(12):1555-61. PMID: 26261044.
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    36. Bann D, Hire D, Manini T, Cooper R, Botoseneanu A, McDermott MM, Pahor M, Glynn NW, Fielding R, King AC, Church T, Ambrosius WT, Gill TM. Correction: Light intensity physical activity and sedentary behavior in relation to body mass index and grip strength in older adults: cross-sectional findings from the Lifestyle Interventions and Independence for Elders (LIFE) study. PLoS One. 2015; 10(4):e0126063. PMID: 25875330.
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    37. Fitzgerald JD, Johnson L, Hire DG, Ambrosius WT, Anton SD, Dodson JA, Marsh AP, McDermott MM, Nocera JR, Tudor-Locke C, White DK, Yank V, Pahor M, Manini TM, Buford TW. Association of objectively measured physical activity with cardiovascular risk in mobility-limited older adults. J Am Heart Assoc. 2015 Feb 18; 4(2). PMID: 25696062.
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    38. Bann D, Hire D, Manini T, Cooper R, Botoseneanu A, McDermott MM, Pahor M, Glynn NW, Fielding R, King AC, Church T, Ambrosius WT, Gill TM, Gill T. Light Intensity physical activity and sedentary behavior in relation to body mass index and grip strength in older adults: cross-sectional findings from the Lifestyle Interventions and Independence for Elders (LIFE) study. PLoS One. 2015; 10(2):e0116058. PMID: 25647685.
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    39. Botoseneanu A, Ambrosius WT, Beavers DP, de Rekeneire N, Anton S, Church T, Folta SC, Goodpaster BH, King AC, Nicklas BJ, Spring B, Wang X, Gill TM. Prevalence of metabolic syndrome and its association with physical capacity, disability, and self-rated health in Lifestyle Interventions and Independence for Elders Study participants. J Am Geriatr Soc. 2015 Feb; 63(2):222-32. PMID: 25645664.
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    40. Hugenschmidt CE, Lovato JF, Ambrosius WT, Bryan RN, Gerstein HC, Horowitz KR, Launer LJ, Lazar RM, Murray AM, Chew EY, Danis RP, Williamson JD, Miller ME, Ding J. The cross-sectional and longitudinal associations of diabetic retinopathy with cognitive function and brain MRI findings: the Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial. Diabetes Care. 2014 Dec; 37(12):3244-52. PMID: 25193529.
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    41. Chew EY, Davis MD, Danis RP, Lovato JF, Perdue LH, Greven C, Genuth S, Goff DC, Leiter LA, Ismail-Beigi F, Ambrosius WT. The effects of medical management on the progression of diabetic retinopathy in persons with type 2 diabetes: the Action to Control Cardiovascular Risk in Diabetes (ACCORD) Eye Study. Ophthalmology. 2014 Dec; 121(12):2443-51. PMID: 25172198.
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    42. Mottl AK, Pajewski N, Fonseca V, Ismail-Beigi F, Chew E, Ambrosius WT, Greven C, Schubart U, Buse J. The degree of retinopathy is equally predictive for renal and macrovascular outcomes in the ACCORD Trial. J Diabetes Complications. 2014 Nov-Dec; 28(6):874-9. PMID: 25123755.
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    43. Casanova R, Saldana S, Chew EY, Danis RP, Greven CM, Ambrosius WT. Application of random forests methods to diabetic retinopathy classification analyses. PLoS One. 2014; 9(6):e98587. PMID: 24940623.
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    44. Pahor M, Guralnik JM, Ambrosius WT, Blair S, Bonds DE, Church TS, Espeland MA, Fielding RA, Gill TM, Groessl EJ, King AC, Kritchevsky SB, Manini TM, McDermott MM, Miller ME, Newman AB, Rejeski WJ, Sink KM, Williamson JD. Effect of structured physical activity on prevention of major mobility disability in older adults: the LIFE study randomized clinical trial. JAMA. 2014 Jun 18; 311(23):2387-96. PMID: 24866862.
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    45. Ambrosius WT, Sink KM, Foy CG, Berlowitz DR, Cheung AK, Cushman WC, Fine LJ, Goff DC, Johnson KC, Killeen AA, Lewis CE, Oparil S, Reboussin DM, Rocco MV, Snyder JK, Williamson JD, Wright JT, Whelton PK. The design and rationale of a multicenter clinical trial comparing two strategies for control of systolic blood pressure: the Systolic Blood Pressure Intervention Trial (SPRINT). Clin Trials. 2014 Oct; 11(5):532-46. PMID: 24902920.
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    46. Simons-Morton DG, Chan JC, Kimel AR, Linz PE, Stowe CL, Summerson J, Ambrosius WT. Characteristics associated with informed consent for genetic studies in the ACCORD trial. Contemp Clin Trials. 2014 Jan; 37(1):155-64. PMID: 24355197.
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    47. Miller ME, Williamson JD, Gerstein HC, Byington RP, Cushman WC, Ginsberg HN, Ambrosius WT, Lovato L, Applegate WB. Effects of randomization to intensive glucose control on adverse events, cardiovascular disease, and mortality in older versus younger adults in the ACCORD Trial. Diabetes Care. 2014; 37(3):634-43. PMID: 24170759.
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    48. Beavers KM, Beavers DP, Nesbit BA, Ambrosius WT, Marsh AP, Nicklas BJ, Rejeski WJ. Effect of an 18-month physical activity and weight loss intervention on body composition in overweight and obese older adults. Obesity (Silver Spring). 2014 Feb; 22(2):325-31. PMID: 23963786.
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    49. Marsh AP, Janssen JA, Ambrosius WT, Burdette JH, Gaukstern JE, Morgan AR, Nesbit BA, Paolini JB, Sheedy JL, Rejeski WJ. The Cooperative Lifestyle Intervention Program-II (CLIP-II): design and methods. Contemp Clin Trials. 2013 Nov; 36(2):382-93. PMID: 23974035.
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    50. Gangaputra S, Lovato JF, Hubbard L, Davis MD, Esser BA, Ambrosius WT, Chew EY, Greven C, Perdue LH, Wong WT, Condren A, Wilkinson CP, Agrón E, Adler S, Danis RP. Comparison of standardized clinical classification with fundus photograph grading for the assessment of diabetic retinopathy and diabetic macular edema severity. Retina. 2013 Jul-Aug; 33(7):1393-9. PMID: 23615341.
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    51. Beavers KM, Ambrosius WT, Nicklas BJ, Rejeski WJ. Independent and combined effects of physical activity and weight loss on inflammatory biomarkers in overweight and obese older adults. J Am Geriatr Soc. 2013 Jul; 61(7):1089-94. PMID: 23772804.
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    52. Schwartz AV, Vittinghoff E, Margolis KL, Scibora LM, Palermo L, Ambrosius WT, Hue TF, Ensrud KE. Intensive glycemic control and thiazolidinedione use: effects on cortical and trabecular bone at the radius and tibia. Calcif Tissue Int. 2013 May; 92(5):477-86. PMID: 23377193.
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    53. Gerstein HC, Ambrosius WT, Danis R, Ismail-Beigi F, Cushman W, Calles J, Banerji M, Schubart U, Chew EY. Diabetic retinopathy, its progression, and incident cardiovascular events in the ACCORD trial. Diabetes Care. 2013 May; 36(5):1266-71. PMID: 23238658.
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    54. Brawley L, Rejeski WJ, Gaukstern JE, Ambrosius WT. Social cognitive changes following weight loss and physical activity interventions in obese, older adults in poor cardiovascular health. Ann Behav Med. 2012 Dec; 44(3):353-64. PMID: 22773225.
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    55. Schwartz AV, Margolis KL, Sellmeyer DE, Vittinghoff E, Ambrosius WT, Bonds DE, Josse RG, Schnall AM, Simmons DL, Hue TF, Palermo L, Hamilton BP, Green JB, Atkinson HH, O'Connor PJ, Force RW, Bauer DC. Intensive glycemic control is not associated with fractures or falls in the ACCORD randomized trial. Diabetes Care. 2012 Jul; 35(7):1525-31. PMID: 22723583.
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    56. Ambrosius WT, Polonsky TS, Greenland P, Goff DC, Perdue LH, Fortmann SP, Margolis KL, Pajewski NM. Design of the value of imaging in enhancing the wellness of your heart (VIEW) trial and the impact of uncertainty on power. Clin Trials. 2012 Apr; 9(2):232-46. PMID: 22333998.
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    57. Samaropoulos XF, Light L, Ambrosius WT, Marcovina SM, Probstfield J, Goff DC. The effect of intensive risk factor management in type 2 diabetes on inflammatory biomarkers. Diabetes Res Clin Pract. 2012 Mar; 95(3):389-98. PMID: 22019270.
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    58. Rejeski WJ, Mihalko SL, Ambrosius WT, Bearon LB, McClelland JW. Weight loss and self-regulatory eating efficacy in older adults: the cooperative lifestyle intervention program. J Gerontol B Psychol Sci Soc Sci. 2011 May; 66(3):279-86. PMID: 21292809.
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    59. Rejeski WJ, Brubaker PH, Goff DC, Bearon LB, McClelland JW, Perri MG, Ambrosius WT. Translating weight loss and physical activity programs into the community to preserve mobility in older, obese adults in poor cardiovascular health. Arch Intern Med. 2011 May 23; 171(10):880-6. PMID: 21263080.
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    60. Chew EY, Ambrosius WT. Update of the ACCORD Eye Study. N Engl J Med. 2011 Jan 13; 364(2):188-9. PMID: 21226603.
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    61. Chew EY, Ambrosius WT, Davis MD, Danis RP, Gangaputra S, Greven CM, Hubbard L, Esser BA, Lovato JF, Perdue LH, Goff DC, Cushman WC, Ginsberg HN, Elam MB, Genuth S, Gerstein HC, Schubart U, Fine LJ. Effects of medical therapies on retinopathy progression in type 2 diabetes. N Engl J Med. 2010 Jul 15; 363(3):233-44. PMID: 20587587.
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    62. Ambrosius WT, Mahnken JD. Power for studies with random group sizes. Stat Med. 2010 May 10; 29(10):1137-44. PMID: 20222151.
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    63. Riddle MC, Ambrosius WT, Brillon DJ, Buse JB, Byington RP, Cohen RM, Goff DC, Malozowski S, Margolis KL, Probstfield JL, Schnall A, Seaquist ER. Epidemiologic relationships between A1C and all-cause mortality during a median 3.4-year follow-up of glycemic treatment in the ACCORD trial. Diabetes Care. 2010 May; 33(5):983-90. PMID: 20427682.
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    64. Ambrosius WT, Danis RP, Goff DC, Greven CM, Gerstein HC, Cohen RM, Riddle MC, Miller ME, Buse JB, Bonds DE, Peterson KA, Rosenberg YD, Perdue LH, Esser BA, Seaquist LA, Felicetta JV, Chew EY. Lack of association between thiazolidinediones and macular edema in type 2 diabetes: the ACCORD eye substudy. Arch Ophthalmol. 2010 Mar; 128(3):312-8. PMID: 20212201.
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    65. Wideman L, Baker CF, Brown PK, Consitt LA, Ambrosius WT, Schechter MS. Substrate utilization during and after exercise in mild cystic fibrosis. Med Sci Sports Exerc. 2009 Feb; 41(2):270-8. PMID: 19127200.
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    66. Miller DP, Furberg CD, Small RH, Millman FM, Ambrosius WT, Harshbarger JS, Ohl CA. Controlling prescription drug expenditures: a report of success. Am J Manag Care. 2007 Aug; 13(8):473-80. PMID: 17685828.
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    67. Atkinson HH, Rosano C, Simonsick EM, Williamson JD, Davis C, Ambrosius WT, Rapp SR, Cesari M, Newman AB, Harris TB, Rubin SM, Yaffe K, Satterfield S, Kritchevsky SB. Cognitive function, gait speed decline, and comorbidities: the health, aging and body composition study. J Gerontol A Biol Sci Med Sci. 2007 Aug; 62(8):844-50. PMID: 17702875.
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    68. Chew EY, Ambrosius WT, Howard LT, Greven CM, Johnson S, Danis RP, Davis MD, Genuth S, Domanski M. Rationale, design, and methods of the Action to Control Cardiovascular Risk in Diabetes Eye Study (ACCORD-EYE). Am J Cardiol. 2007 Jun 18; 99(12A):103i-111i. PMID: 17599420.
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    69. Irwin RW, Watson T, Minick RP, Ambrosius WT. Age, body mass index, and gender differences in sacroiliac joint pathology. Am J Phys Med Rehabil. 2007 Jan; 86(1):37-44. PMID: 17304687.
      Citations:    
    70. Case LD, Ambrosius WT. Power and sample size. Methods Mol Biol. 2007; 404:377-408. PMID: 18450060.
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    71. Crouse JR, Elam MB, Robinson JG, Ambrosius WT, Ginsberg HN. Cholesterol management: targeting a lower low-density lipoprotein cholesterol concentration increases adult treatment panel-III goal attainment. Am J Cardiol. 2006 Jun 01; 97(11):1667-9. PMID: 16728235.
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    72. Focht BC, Rejeski WJ, Ambrosius WT, Katula JA, Messier SP. Exercise, self-efficacy, and mobility performance in overweight and obese older adults with knee osteoarthritis. Arthritis Rheum. 2005 Oct 15; 53(5):659-65. PMID: 16208674.
      Citations:    
    73. Goff DC, Massing MW, Bertoni AG, Davis J, Ambrosius WT, McArdle J, Duren-Winfield V, Sueta CA, Croft JB. Enhancing quality of heart failure care in managed Medicare and Medicaid in North Carolina: results of the North Carolina Achieving Cardiac Excellence (NC ACE) Project. Am Heart J. 2005 Oct; 150(4):717-24. PMID: 16209973.
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    74. Holmes RP, Ambrosius WT, Assimos DG. Dietary oxalate loads and renal oxalate handling. J Urol. 2005 Sep; 174(3):943-7; discussion 947. PMID: 16094002.
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    75. Saha C, Eckert GJ, Ambrosius WT, Chun TY, Wagner MA, Zhao Q, Pratt JH. Improvement in blood pressure with inhibition of the epithelial sodium channel in blacks with hypertension. Hypertension. 2005 Sep; 46(3):481-7. PMID: 16116042.
      Citations:    
    76. Cesari M, Kritchevsky SB, Baumgartner RN, Atkinson HH, Penninx BW, Lenchik L, Palla SL, Ambrosius WT, Tracy RP, Pahor M. Sarcopenia, obesity, and inflammation--results from the Trial of Angiotensin Converting Enzyme Inhibition and Novel Cardiovascular Risk Factors study. Am J Clin Nutr. 2005 Aug; 82(2):428-34. PMID: 16087989.
      Citations:    
    77. Shankar RR, Ferrari P, Dick B, Ambrosius WT, Eckert GJ, Pratt JH. Activity of 11beta-hydroxysteroid dehydrogenase type 2 in normotensive blacks and whites. Ethn Dis. 2005; 15(3):407-10. PMID: 16108299.
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    78. Penninx BW, Abbas H, Ambrosius W, Nicklas BJ, Davis C, Messier SP, Pahor M. Inflammatory markers and physical function among older adults with knee osteoarthritis. J Rheumatol. 2004 Oct; 31(10):2027-31. PMID: 15468370.
      Citations:    
    79. Ambrosius WT, Hui SL. Cross calibration in longitudinal studies. Stat Med. 2004 Sep 30; 23(18):2845-61. PMID: 15344190.
      Citations:    
    80. Focht BC, Brawley LR, Rejeski WJ, Ambrosius WT. Group-mediated activity counseling and traditional exercise therapy programs: effects on health-related quality of life among older adults in cardiac rehabilitation. Ann Behav Med. 2004 Aug; 28(1):52-61. PMID: 15249259.
      Citations:    
    81. Carter CS, Cesari M, Ambrosius WT, Hu N, Diz D, Oden S, Sonntag WE, Pahor M. Angiotensin-converting enzyme inhibition, body composition, and physical performance in aged rats. J Gerontol A Biol Sci Med Sci. 2004 May; 59(5):416-23. PMID: 15123750.
      Citations:    
    82. Nicklas BJ, Ambrosius W, Messier SP, Miller GD, Penninx BW, Loeser RF, Palla S, Bleecker E, Pahor M. Diet-induced weight loss, exercise, and chronic inflammation in older, obese adults: a randomized controlled clinical trial. Am J Clin Nutr. 2004 Apr; 79(4):544-51. PMID: 15051595.
      Citations:    
    83. Bertoni AG, Duren-Winfield V, Ambrosius WT, McArdle J, Sueta CA, Massing MW, Peacock S, Davis J, Croft JB, Goff DC. Quality of heart failure care in managed Medicare and Medicaid patients in North Carolina. Am J Cardiol. 2004 Mar 15; 93(6):714-8. PMID: 15019875.
      Citations:    
    84. Ambrosius WT, Lange EM, Langefeld CD. Power for genetic association studies with random allele frequencies and genotype distributions. Am J Hum Genet. 2004 Apr; 74(4):683-93. PMID: 15024689.
      Citations:    
    85. Patel N, Sacks D, Patel RI, Moresco KP, Ouriel K, Gray R, Ambrosius WT, Lewis CA. SIR reporting standards for the treatment of acute limb ischemia with use of transluminal removal of arterial thrombus. J Vasc Interv Radiol. 2003 Sep; 14(9 Pt 2):S453-65. PMID: 14514861.
      Citations:    
    86. Gorski JC, Vannaprasaht S, Hamman MA, Ambrosius WT, Bruce MA, Haehner-Daniels B, Hall SD. The effect of age, sex, and rifampin administration on intestinal and hepatic cytochrome P450 3A activity. Clin Pharmacol Ther. 2003 Sep; 74(3):275-87. PMID: 12966371.
      Citations:    
    87. Rejeski WJ, Brawley LR, Ambrosius WT, Brubaker PH, Focht BC, Foy CG, Fox LD. Older adults with chronic disease: benefits of group-mediated counseling in the promotion of physically active lifestyles. Health Psychol. 2003 Jul; 22(4):414-23. PMID: 12940398.
      Citations:    
    88. Dunn DW, Austin JK, Harezlak J, Ambrosius WT. ADHD and epilepsy in childhood. Dev Med Child Neurol. 2003 Jan; 45(1):50-4. PMID: 12549755.
      Citations:    
    89. Brashear A, McAfee AL, Kuhn ER, Ambrosius WT. Treatment with botulinum toxin type B for upper-limb spasticity. Arch Phys Med Rehabil. 2003 Jan; 84(1):103-7. PMID: 12589629.
      Citations:    
    90. Pratt JH, Ambrosius WT, Agarwal R, Eckert GJ, Newman S. Racial difference in the activity of the amiloride-sensitive epithelial sodium channel. Hypertension. 2002 Dec; 40(6):903-8. PMID: 12468577.
      Citations:    
    91. Ambrosius WT, Manatunga AK. Intensive short courses in biostatistics for fellows and physicians. Stat Med. 2002 Sep 30; 21(18):2739-56. PMID: 12228888.
      Citations:    
    92. Trerotola SO, Kraus M, Shah H, Namyslowski J, Johnson MS, Stecker MS, Ahmad I, McLennan G, Patel NH, O'Brien E, Lane KA, Ambrosius WT. Randomized comparison of split tip versus step tip high-flow hemodialysis catheters. Kidney Int. 2002 Jul; 62(1):282-9. PMID: 12081590.
      Citations:    
    93. Dunn DW, Harezlak J, Ambrosius WT, Austin JK, Hale B. Teacher assessment of behaviour in children with new-onset seizures. Seizure. 2002 Apr; 11(3):169-75. PMID: 12018960.
      Citations:    
    94. Huberty TJ, Austin JK, Harezlak J, Dunn DW, Ambrosius WT. Informant Agreement in Behavior Ratings for Children with Epilepsy. Epilepsy Behav. 2000 Dec; 1(6):427-435. PMID: 12737832.
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