Small double-stranded, non-protein coding RNAs, 21-25 nucleotides in length generated from single-stranded microRNA gene transcripts by the same RIBONUCLEASE III, Dicer, that produces small interfering RNAs (RNA, SMALL INTERFERING). They become part of the RNA-INDUCED SILENCING COMPLEX and repress the translation (TRANSLATION, GENETIC) of target RNA by binding to homologous 3'UTR region as an imperfect match. The small temporal RNAs (stRNAs), let-7 and lin-4, from C. elegans, are the first 2 miRNAs discovered, and are from a class of miRNAs involved in developmental timing.

Descriptor ID	D035683
MeSH Number(s)	D13.150.650.319 D13.444.735.150.319 D13.444.735.790.552.500
Concept/Terms	MicroRNAs MicroRNAs miRNAs miRNA Micro RNA RNA, Micro MicroRNA Primary MicroRNA Primary MicroRNA MicroRNA, Primary Primary miRNA miRNA, Primary pri-miRNA pri miRNA RNA, Small Temporal RNA, Small Temporal Temporal RNA, Small stRNA Small Temporal RNA pre-miRNA pre-miRNA pre miRNA

Below are MeSH descriptors whose meaning is more general than "MicroRNAs".

Below are MeSH descriptors whose meaning is related to "MicroRNAs".

Below are MeSH descriptors whose meaning is more specific than "MicroRNAs".