"Receptor, trkA" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A protein-tyrosine kinase receptor that is specific for NERVE GROWTH FACTOR; NEUROTROPHIN 3; neurotrophin 4, neurotrophin 5. It plays a crucial role in pain sensation and thermoregulation in humans. Gene mutations that cause loss of receptor function are associated with CONGENITAL INSENSITIVITY TO PAIN WITH ANHIDROSIS, while gene rearrangements that activate the protein-tyrosine kinase function are associated with tumorigenesis.
| Descriptor ID |
D020917
|
| MeSH Number(s) |
D08.811.913.696.620.682.725.400.660 D12.776.543.750.060.496 D12.776.543.750.750.400.550.550
|
| Concept/Terms |
Receptor, trkA- Receptor, trkA
- gp140 c-trk
- c-trk, gp140
- gp140 c trk
- gp140(c-TRK)
- Neurotrophic Tyrosine Kinase Receptor Type 1
- NTRK1 Receptor
- Receptor, NTRK1
- p140-trkA
- p140 trkA
- Proto-Oncogene Protein trk
- Proto Oncogene Protein trk
- trk, Proto-Oncogene Protein
- Receptor, Neurotrophic Tyrosine Kinase Type 1
- trk Proto-Oncogene Protein
- Proto-Oncogene Protein, trk
- trk Proto Oncogene Protein
- trk1 Transforming Tryrosine Kinase
- trkA Receptor
- c-trk Protein
- c trk Protein
- Proto-Oncogene Products c-trk
- Proto Oncogene Products c trk
- c-trk, Proto-Oncogene Products
|
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