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Yashashwi Pokharel MD, MSCR

TitleAssistant Professor
InstitutionWake Forest School of Medicine
DepartmentInternal Medicine, Cardiovascular Medicine
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    Other Positions
    TitleAssistant Professor
    InstitutionWake Forest School of Medicine
    DepartmentPublic Health Sciences (Division of)


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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Caldarera T, Ponir C, Seals A, Penmetsa M, Ip E, German CA, Virani SS, Saha A, Bosworth HB, Moore JB, Shapiro MD, Pokharel Y. Clinicians' self-reported efficacy in cardiovascular prevention practice in the southeastern United States. Future Cardiol. 2023 Sep; 19(12):593-604. PMID: 37916575.
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    2. Ponir C, Annabathula R, Caldarera T, Penmetsa M, Seals A, Saha A, Moore JB, Bosworth HB, Ip EH, Shapiro MD, Pokharel Y. Availability of Specialty Services for Cardiovascular Prevention Practice in the Southeastern United States. South Med J. 2023 Nov; 116(11):848-856. PMID: 37913802.
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    3. Ponir C, Seals A, Caldarera T, Ip EH, German CA, Taylor Y, Moore JB, Bosworth HB, Shapiro MD, Pokharel Y. Specialty preference for cardiovascular prevention practice in the Southeast US and role of a preventive cardiologist. Postgrad Med J. 2023 Oct 19. PMID: 37857510.
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    4. Nguyen HM, Mahabaleshwarkar R, Nandkeolyar S, Pokharel Y, McWilliams A, Taylor Y. Blood Pressure Control in a Diverse Population of Hypertensive Patients With Heart Failure. Am J Cardiol. 2023 Oct 06; 208:25-30. PMID: 37806186.
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    5. Pokharel Y, Kokkinidis DG, Wang J, Gosch KL, Safley DM, Spertus JA, Mena-Hurtado C, Smolderen KG. Predictors of Revascularization in Lower-Extremity Peripheral Artery Disease: Insights From the PORTRAIT Study. J Endovasc Ther. 2023 Jun 13; 15266028231179574. PMID: 37309164.
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    6. Mehta A, Bansal M, Pokharel Y, Vallabhajosyula S. Constrictive Pericarditis: A Diagnostic Conundrum. Cureus. 2023 May; 15(5):e39485. PMID: 37362484.
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    7. Park CJ, Vasu S, Urbain JL, Triozzi PL, Pokharel Y. A First Suspected Case of Fibrosing Mediastinitis After Anti-PD-1 Therapy. JACC Case Rep. 2022 Oct 19; 4(20):1363-1365. PMID: 36299648.
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    8. Chevli PA, Islam T, Pokharel Y, Rodriguez F, Virani SS, Blaha MJ, Bertoni AG, Budoff M, Otvos JD, Shapiro MD. Association between remnant lipoprotein cholesterol, high-sensitivity C-reactive protein, and risk of atherosclerotic cardiovascular disease events in the Multi-Ethnic Study of Atherosclerosis (MESA). J Clin Lipidol. 2022 Sep 19. PMID: 36180367.
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    9. Pokharel Y, Karmacharya BM, Neupane D. Hypertension-A Silent Killer Without Global Bounds: What Next? J Am Coll Cardiol. 2022 Aug 23; 80(8):818-820. PMID: 35981825.
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    10. Jain V, Al Rifai M, Khan SU, Kalra A, Rodriguez F, Samad Z, Pokharel Y, Misra A, Sperling LS, Rana JS, Ullah W, Medhekar A, Virani SS. Association Between Social Vulnerability Index and Cardiovascular Disease: A Behavioral Risk Factor Surveillance System Study. J Am Heart Assoc. 2022 Aug 02; 11(15):e024414. PMID: 35904206.
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    11. Timsina MK, Peltzer JN, Pokharel Y, Peterson JM, Schwartz LJ, LeMaster JW. Understanding Medication Adherence in Bhutanese Refugees With Diabetes in a Midwestern City. J Transcult Nurs. 2022 May; 33(3):324-333. PMID: 35311407.
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    12. Bhattarai H, McLachlan CS, Khanal P, Adhikari TB, Ranabhat K, Koirala S, Parajuli SB, Pokharel Y, Paudel S, Soti PB, Subedi B, Wagle CN, Mahato S, Pandey G, Gyawali P, Pandey S, Gyawali V, Devkota S, Lohani GR, Koirala B, Xia X, Beaney T, Neupane D. May Measurement Month 2019: an analysis of blood pressure screening results from Nepal. Eur Heart J Suppl. 2021 May; 23(Suppl B):B110-B113. PMID: 34054371.
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    13. Kheiri B, Simpson TF, Osman M, Balla S, Rahmouni H, Mehta A, Pokharel Y, Nasir K, Fazio S, Shapiro MD. Familial hypercholesterolemia related admission for acute coronary syndrome in the United States: Incidence, predictors, and outcomes. J Clin Lipidol. 2021 May-Jun; 15(3):460-465. PMID: 34053910.
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    14. Ghimire U, Shrestha N, Adhikari B, Mehata S, Pokharel Y, Mishra SR. Health system's readiness to provide cardiovascular, diabetes and chronic respiratory disease related services in Nepal: analysis using 2015 health facility survey. BMC Public Health. 2020 Jul 25; 20(1):1163. PMID: 32711487.
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    15. Neupane G, Acharya S, Bhattarai M, Upadhyay A, Belbase B, Bhandari M, Pandeya D, Pokharel S, Ghimire S, Thapa G, Karmacharya B, Bhatt MR, Spertus JA, Neupane D, Timsina L, Pokharel Y. Study, Design, and Rationale of Noncommunicable Diseases in Nepal (NCD Nepal) Study: A Community-Based Prospective Epidemiological and Implementation Study in Rural Nepal. Glob Adv Health Med. 2020; 9:2164956120917379. PMID: 32284911.
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    16. Neupane D, Rijal A, Henry ME, Kallestrup P, Koirala B, Mclachlan CS, Ghimire K, Zhao D, Sharma S, Pokharel Y, Joseph K, Olsen MH, Schutte AE, Appel LJ. Mean dietary salt intake in Nepal: A population survey with 24-hour urine collections. J Clin Hypertens (Greenwich). 2020 02; 22(2):273-279. PMID: 31967732.
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    17. Pokharel Y, Mouhanna F, Schneider ALC, Rawlings AM, Knopman DS, Nambi V, Virani SS, Hoogeveen RC, Alonso A, Heiss G, Coresh J, Mosley T, Gottesman R, Selvin E, Ballantyne C, Power MC. High-Sensitive Troponin T, Natriuretic Peptide, and Cognitive Change. J Am Geriatr Soc. 2019 11; 67(11):2353-2361. PMID: 31359423.
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    18. Grodzinsky A, Pokharel Y, Myadam R. Don't stop at statins: complementary PCSK9 use in patients at high risk for recurrent cardiac events. Eur Heart J Qual Care Clin Outcomes. 2019 07 01; 5(3):193-194. PMID: 30882136.
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    19. Bhardwaj B, Spertus JA, Kennedy KF, Jones WS, Safley D, Tsai TT, Aronow HD, Vora AN, Pokharel Y, Kumar A, Attaran RR, Feldman DN, Armstrong E, Prasad A, Gray B, Salisbury AC. Bleeding Complications in Lower-Extremity Peripheral Vascular Interventions: Insights From the NCDR PVI Registry. JACC Cardiovasc Interv. 2019 06 24; 12(12):1140-1149. PMID: 31221303.
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    20. Mishra SR, Ghimire S, Joshi C, Gyawali B, Shrestha A, Neupane D, Sharma SR, Pokharel Y, Virani SS. Cardio-metabolic disease risk factors among South Asian labour migrants to the Middle East: a scoping review and policy analysis. Global Health. 2019 05 02; 15(1):33. PMID: 31046779.
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    21. Pokharel Y, Mouhanna F, Nambi V, Virani SS, Hoogeveen R, Alonso A, Heiss G, Coresh J, Mosley T, Gottesman RF, Ballantyne CM, Power MC. ApoB, small-dense LDL-C, Lp(a), LpPLA2 activity, and cognitive change. Neurology. 2019 05 28; 92(22):e2580-e2593. PMID: 31043469.
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    22. Hira RS, Kataruka A, Akeroyd JM, Ramsey DJ, Pokharel Y, Gurm HS, Nasir K, Deswal A, Jneid H, Alam M, Ballantyne CM, Petersen LA, Virani SS. Association of Body Mass Index With Risk Factor Optimization and Guideline-Directed Medical Therapy in US Veterans With Cardiovascular Disease. Circ Cardiovasc Qual Outcomes. 2019 01; 12(1):e004817. PMID: 30636483.
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    23. Khariton Y, Patel KK, Chan PS, Pokharel Y, Wang J, Spertus JA, Safley DM, Hiatt WR, Smolderen KG. Guideline-directed statin intensification in patients with new or worsening symptoms of peripheral artery disease. Clin Cardiol. 2018 Nov; 41(11):1414-1422. PMID: 30284297.
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    24. Pokharel Y, Jones PG, Graham G, Collins T, Regensteiner JG, Murphy TP, Cohen D, Spertus JA, Smolderen K. Racial Heterogeneity in Treatment Effects in Peripheral Artery Disease: Insights From the CLEVER Trial (Claudication: Exercise Versus Endoluminal Revascularization). Circ Cardiovasc Qual Outcomes. 2018 04; 11(4):e004157. PMID: 29643064.
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    25. Qintar M, Sharma PP, Pokharel Y, Tang Y, Lu Y, Jones P, Dreyer RP, Spertus JA. Prevalence and predictors of elevated high-sensitivity C-reactive protein in post-myocardial infarction patients: Insights from the VIRGO and TRIUMPH registries. Clin Cardiol. 2017 Dec; 40(12):1205-1211. PMID: 29247528.
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    26. Pokharel Y, Khariton Y, Tang Y, Nassif ME, Chan PS, Arnold SV, Jones PG, Spertus JA. Association of Serial Kansas City Cardiomyopathy Questionnaire Assessments With Death and Hospitalization in Patients With Heart Failure With Preserved and Reduced Ejection Fraction: A Secondary Analysis of 2 Randomized Clinical Trials. JAMA Cardiol. 2017 12 01; 2(12):1315-1321. PMID: 29094152.
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    27. Pokharel Y, Tang Y, Bhardwaj B, Patel KK, Qintar M, O'Keefe JH, Kulkarni KR, Jones PH, Martin SS, Virani SS, Spertus JA. Association of low-density lipoprotein pattern with mortality after myocardial infarction: Insights from the TRIUMPH study. J Clin Lipidol. 2017 Nov - Dec; 11(6):1458-1470.e4. PMID: 29050980.
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    28. Pokharel Y, Sharma PP, Qintar M, Lu Y, Tang Y, Jones P, Dreyer RP, Spertus JA. High-sensitivity C-reactive protein levels and health status outcomes after myocardial infarction. Atherosclerosis. 2017 Nov; 266:16-23. PMID: 28946036.
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    29. Power MC, Rawlings A, Sharrett AR, Bandeen-Roche K, Coresh J, Ballantyne CM, Pokharel Y, Michos ED, Penman A, Alonso A, Knopman D, Mosley TH, Gottesman RF. Association of midlife lipids with 20-year cognitive change: A cohort study. Alzheimers Dement. 2018 02; 14(2):167-177. PMID: 28916238.
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    30. Agarwala A, Pokharel Y, Saeed A, Sun W, Virani SS, Nambi V, Ndumele C, Shahar E, Heiss G, Boerwinkle E, Konety S, Hoogeveen RC, Ballantyne CM. The association of lipoprotein(a) with incident heart failure hospitalization: Atherosclerosis Risk in Communities study. Atherosclerosis. 2017 07; 262:131-137. PMID: 28554015.
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    31. Pokharel Y, Chinnakondepalli K, Vilain K, Wang K, Mark DB, Davies G, Blazing MA, Giugliano RP, Braunwald E, Cannon CP, Cohen DJ, Magnuson EA. Impact of Ezetimibe on the Rate of Cardiovascular-Related Hospitalizations and Associated Costs Among Patients With a Recent Acute Coronary Syndrome: Results From the IMPROVE-IT Trial (Improved Reduction of Outcomes: Vytorin Efficacy International Trial). Circ Cardiovasc Qual Outcomes. 2017 05; 10(5). PMID: 28506979.
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    32. Pokharel Y, Tang F, Jones PG, Nambi V, Bittner VA, Hira RS, Nasir K, Chan PS, Maddox TM, Oetgen WJ, Heidenreich PA, Borden WB, Spertus JA, Petersen LA, Ballantyne CM, Virani SS. Adoption of the 2013 American College of Cardiology/American Heart Association Cholesterol Management Guideline in Cardiology Practices Nationwide. JAMA Cardiol. 2017 04 01; 2(4):361-369. PMID: 28249067.
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    33. Patel KK, Arnold SV, Chan PS, Tang Y, Pokharel Y, Jones PG, Spertus JA. Personalizing the Intensity of Blood Pressure Control: Modeling the Heterogeneity of Risks and Benefits From SPRINT (Systolic Blood Pressure Intervention Trial). Circ Cardiovasc Qual Outcomes. 2017 04; 10(4). PMID: 28373269.
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    34. Qintar M, Chhatriwalla AK, Arnold SV, Tang F, Buchanan DM, Shafiq A, Pokharel Y, deBronkart D, Ashraf JM, Spertus JA. Beyond restenosis: Patients' preference for drug eluting or bare metal stents. Catheter Cardiovasc Interv. 2017 Sep 01; 90(3):357-363. PMID: 28168845.
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    35. Pokharel Y, Sun W, Virani SS, Nambi V, Hoogeveen RC, Chang PP, Ndumele CE, Solomon SD, Bozkurt B, Selvin E, Ballantyne CM, Deswal A. Myocardial Injury, Obesity, and the Obesity Paradox: The ARIC Study. JACC Heart Fail. 2017 01; 5(1):56-63. PMID: 28017350.
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    36. Pokharel Y, Sun W, Villareal DT, Selvin E, Virani SS, Ndumele CE, Hoogeveen RC, Coresh J, Boerwinkle E, Butler KR, Solomon SD, Pankow JS, Bozkurt B, Ballantyne CM, Nambi V. Association between high-sensitivity troponin T and cardiovascular risk in individuals with and without metabolic syndrome: The ARIC study. Eur J Prev Cardiol. 2017 04; 24(6):628-638. PMID: 27941157.
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    37. Pokharel Y, Gosch K, Nambi V, Chan PS, Kosiborod M, Oetgen WJ, Spertus JA, Ballantyne CM, Petersen LA, Virani SS. Practice-Level Variation in Statin Use Among Patients With Diabetes: Insights From the PINNACLE Registry. J Am Coll Cardiol. 2016 09 20; 68(12):1368-9. PMID: 27634128.
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    38. Khan IM, Pokharel Y, Dadu RT, Lewis DE, Hoogeveen RC, Wu H, Ballantyne CM. Postprandial Monocyte Activation in Individuals With Metabolic Syndrome. J Clin Endocrinol Metab. 2016 11; 101(11):4195-4204. PMID: 27575945.
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    39. Pokharel Y, Akeroyd JM, Virani SS. Cholesterol Guidelines: More Similar Than Different. Prog Cardiovasc Dis. 2016 Sep - Oct; 59(2):190-199. PMID: 27497507.
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    40. Hira RS, Cowart JB, Akeroyd JM, Ramsey DJ, Pokharel Y, Nambi V, Jneid H, Deswal A, Denktas A, Taylor A, Nasir K, Ballantyne CM, Petersen LA, Virani SS. Risk Factor Optimization and Guideline-Directed Medical Therapy in US Veterans With Peripheral Arterial and Ischemic Cerebrovascular Disease Compared to Veterans With Coronary Heart Disease. Am J Cardiol. 2016 Oct 15; 118(8):1144-1149. PMID: 27553104.
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    41. Kalra A, Pokharel Y, Glusenkamp N, Wei J, Kerkar PG, Oetgen WJ, Virani SS. Gender disparities in cardiovascular care access and delivery in India: Insights from the American College of Cardiology's PINNACLE India Quality Improvement Program (PIQIP). Int J Cardiol. 2016 Jul 15; 215:248-51. PMID: 27128540.
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    42. Pokharel Y, Akeroyd JM, Ramsey DJ, Hira RS, Nambi V, Shah T, Woodard LD, Winchester DE, Ballantyne CM, Petersen LA, Virani SS. Statin Use and Its Facility-Level Variation in Patients With Diabetes: Insight From the Veterans Affairs National Database. Clin Cardiol. 2016 Apr; 39(4):185-91. PMID: 27059708.
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    43. deGoma EM, Ahmad ZS, O'Brien EC, Kindt I, Shrader P, Newman CB, Pokharel Y, Baum SJ, Hemphill LC, Hudgins LC, Ahmed CD, Gidding SS, Duffy D, Neal W, Wilemon K, Roe MT, Rader DJ, Ballantyne CM, Linton MF, Duell PB, Shapiro MD, Moriarty PM, Knowles JW. Treatment Gaps in Adults With Heterozygous Familial Hypercholesterolemia in the United States: Data From the CASCADE-FH Registry. Circ Cardiovasc Genet. 2016 Jun; 9(3):240-9. PMID: 27013694.
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    44. Pokharel Y, Steinberg L, Chan W, Akeroyd JM, Jones PH, Nambi V, Nasir K, Petersen L, Ballantyne CM, Virani SS. A dataset to assess providers? knowledge and attitudes towards the 2013 American College of Cardiology/American Heart Association Cholesterol Management Guideline. Data Brief. 2016 Jun; 7:595-8. PMID: 27054163.
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    45. Bilen O, Pokharel Y, Ballantyne CM. Genetic Testing in Hyperlipidemia. Endocrinol Metab Clin North Am. 2016 Mar; 45(1):129-40. PMID: 26893002.
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    46. Pokharel Y, Wei J, Hira RS, Kalra A, Shore S, Kerkar PG, Kumar G, Risch S, Vicera V, Oetgen WJ, Deswal A, Turakhia MP, Glusenkamp N, Virani SS. Guideline-Directed Medication Use in Patients With Heart Failure With Reduced Ejection Fraction in India: American College of Cardiology's PINNACLE India Quality Improvement Program. Clin Cardiol. 2016 Mar; 39(3):145-9. PMID: 26880649.
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    47. Pokharel Y, Steinberg L, Chan W, Akeroyd JM, Jones PH, Nambi V, Nasir K, Petersen L, Ballantyne CM, Virani SS. Case-based educational intervention to assess change in providers' knowledge and attitudes towards the 2013 American College of Cardiology/American Heart Association Cholesterol Management Guideline. Atherosclerosis. 2016 Mar; 246:115-20. PMID: 26773472.
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    48. Virani SS, Pokharel Y, Steinberg L, Chan W, Akeroyd JM, Gowani SA, Kalra A, Polsani V, Miedema MD, Jones PH, Nambi V, Petersen LA, Ballantyne CM. Provider understanding of the 2013 ACC/AHA cholesterol guideline. J Clin Lipidol. 2016 May-Jun; 10(3):497-504.e4. PMID: 27206936.
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    49. Pokharel Y, Sun W, Polfus LM, Folsom AR, Heiss G, Sharrett AR, Boerwinkle E, Ballantyne CM, Hoogeveen RC. Lipoprotein associated phospholipase A2 activity, apolipoprotein C3 loss-of-function variants and cardiovascular disease: The Atherosclerosis Risk In Communities Study. Atherosclerosis. 2015 Aug; 241(2):641-8. PMID: 26117401.
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    50. Kalra A, Pokharel Y, Hira RS, Risch S, Vicera V, Li Q, Kalra RN, Kerkar PG, Kumar G, Maddox TM, Oetgen WJ, Glusenkamp N, Turakhia MP, Virani SS. Cardiovascular Disease Performance Measures in the Outpatient Setting in India: Insights From the American College of Cardiology's PINNACLE India Quality Improvement Program (PIQIP). J Am Heart Assoc. 2015 May 20; 4(5). PMID: 25994444.
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    51. Pokharel Y, Virani SS, Ballantyne CM. The promise of proprotein convertase subtilisin/kexin 9 inhibitors for the treatment of familial hypercholesterolemia. Curr Atheroscler Rep. 2015 May; 17(5):508. PMID: 25782778.
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    52. Bilen O, Pokharel Y, Ballantyne CM. Genetic testing in hyperlipidemia. Cardiol Clin. 2015 May; 33(2):267-75. PMID: 25939299.
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    53. Pokharel Y, Sun W, de Lemos JA, Taffet GE, Virani SS, Ndumele CE, Mosley TH, Hoogeveen RC, Coresh J, Wright JD, Heiss G, Boerwinkle EA, Bozkurt B, Solomon SD, Ballantyne CM, Nambi V. High-sensitivity troponin T and cardiovascular events in systolic blood pressure categories: atherosclerosis risk in communities study. Hypertension. 2015 Jan; 65(1):78-84. PMID: 25350984.
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    54. Pokharel Y, Basra S, Lincoln AE, Tucker AM, Nambi V, Nasir K, Vogel RA, Wong ND, Boone JL, Roberts AJ, Ballantyne CM, Virani SS. Association of body mass index and waist circumference with subclinical atherosclerosis in retired NFL players. South Med J. 2014 Oct; 107(10):633-9. PMID: 25279867.
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    55. Basra SS, Pokharel Y, Hira RS, Bandeali SJ, Nambi V, Deswal A, Nasir K, Martin SS, Vogel RA, Roberts AJ, Ballantyne CM, Virani SS. Relation between playing position and coronary artery calcium scores in retired National Football League players. Am J Cardiol. 2014 Dec 15; 114(12):1836-40. PMID: 25432152.
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    56. Ababneh B, Rejjal L, Pokharel Y, Nambi V, Wang X, Tung CH, Han RI, Taylor AA, Kougias P, Lumsden AB, Lawrie G, Reardon M, Ballantyne CM, Morrisett JD, Brunner G. Distribution of calcification in carotid endarterectomy tissues: comparison of micro-computed tomography imaging with histology. Vasc Med. 2014 Oct; 19(5):343-50. PMID: 25193489.
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    57. Pokharel Y, Nambi V, Martin SS, Hoogeveen RC, Nasir K, Khera A, Wong ND, Jones PH, Boone J, Roberts AJ, Ballantyne CM, Virani SS. Association between lipoprotein associated phospholipase A2 mass and subclinical coronary and carotid atherosclerosis in Retired National Football League players. Atherosclerosis. 2014 Oct; 236(2):251-6. PMID: 25105582.
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    58. Pokharel Y, Macedo FY, Nambi V, Martin SS, Nasir K, Wong ND, Boone J, Roberts AJ, Ballantyne CM, Virani SS. Neck circumference is not associated with subclinical atherosclerosis in retired National Football League players. Clin Cardiol. 2014 Jul; 37(7):402-7. PMID: 24648005.
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    59. Brodie BR, Pokharel Y, Garg A, Kissling G, Hansen C, Milks S, Cooper M, McAlhany C, Stuckey TD. Very late hazard with stenting versus balloon angioplasty for ST-elevation myocardial infarction: a 16-year single-center experience. J Interv Cardiol. 2014 Feb; 27(1):21-8. PMID: 24372979.
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    60. Brodie B, Pokharel Y, Garg A, Kissling G, Hansen C, Milks S, Cooper M, McAlhany C, Stuckey T. Predictors of early, late, and very late stent thrombosis after primary percutaneous coronary intervention with bare-metal and drug-eluting stents for ST-segment elevation myocardial infarction. JACC Cardiovasc Interv. 2012 Oct; 5(10):1043-51. PMID: 23078734.
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    61. Brodie B, Pokharel Y, Fleishman N, Bensimhon A, Kissling G, Hansen C, Milks S, Cooper M, McAlhany C, Stuckey T. Very late stent thrombosis after primary percutaneous coronary intervention with bare-metal and drug-eluting stents for ST-segment elevation myocardial infarction: a 15-year single-center experience. JACC Cardiovasc Interv. 2011 Jan; 4(1):30-8. PMID: 21251626.
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