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Sara Jones PhD

TitleProfessor
InstitutionWake Forest School of Medicine
DepartmentTranslational Neuroscience
Address
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    Other Positions
    TitleProfessor
    InstitutionWake Forest School of Medicine
    DepartmentWake Forest Institute for Regenerative Medicine

    TitleChair
    InstitutionWake Forest School of Medicine
    DepartmentTranslational Neuroscience


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    F32DA005749     (JONES, SARA R)Mar 6, 1996
    NIH
    MOLECULAR MECHANISM OF AMPHETAMINE ACTION
    Role: Principal Investigator
    R01DA014030     (JONES, SARA RAULERSON)Apr 1, 2001 - Mar 31, 2018
    NIH
    Animal Models of Cocaine Addiction
    Role: Principal Investigator
    U01AA014091     (JONES, SARA RAULERSON)Feb 1, 2003 - Jan 31, 2022
    NIH
    Role of Kappa Opioid Receptors in Maladaptive Catecholamine Responses to Stress and Alcohol Exposure
    Role: Principal Investigator
    R21AA013900     (JONES, SARA R)Jun 1, 2004 - May 31, 2009
    NIH
    Ethanol, NMDA Receptor and Dopamine Interactions
    Role: Principal Investigator
    R21DA018815     (JONES, SARA R)Sep 25, 2004 - Jul 31, 2007
    NIH
    Voltammetry in Freely Moving Mice
    Role: Principal Investigator
    R01DA021325     (JONES, SARA R)Jul 20, 2007 - Dec 31, 2013
    NIH
    Dopamine Transporter Changes Following Cocaine Self-Administration
    Role: Principal Investigator
    R01DA030161     (JONES, SARA RAULERSON)Sep 15, 2010 - Jun 30, 2017
    NIH
    Methylphenidate, Serotonin and Dopamine Interactions
    Role: Principal Investigator
    R01AA023999     (JONES, SARA RAULERSON)Aug 5, 2015 - Jun 30, 2020
    NIH
    Ethanol Dependence Induced Changes in Dopamine Signaling in Basolateral Amygdala
    Role: Principal Investigator
    T32DA041349     (JONES, SARA RAULERSON)Jul 1, 2017 - Jun 30, 2022
    NIH
    The Neurobiology of Drug Abuse
    Role: Principal Investigator
    R01DA048490     (MARTIN, THOMAS JEFFREY)Apr 15, 2019 - Feb 29, 2024
    NIH
    Biased Kappa Opioid Agonists as Non-addictive Analgesics
    Role: Co-Principal Investigator
    R13AA028160     (GILPIN, NICHOLAS W.)Sep 15, 2019 - Aug 31, 2021
    NIH
    2020/2022 Alcohol and the Nervous System Gordon Research Conference & Gordon Research Seminar
    Role: Co-Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Voisin DA, Wakeford A, Nye J, Mun J, Jones SR, Locke J, Huhman KL, Wilson ME, Albers HE, Michopoulos V. Sex and social status modify the effects of fluoxetine on socioemotional behaviors in Syrian hamsters and rhesus macaques. Pharmacol Biochem Behav. 2022 Feb 24; 215:173362. PMID: 35219757.
      Citations:    
    2. Bloch S, Holleran KM, Kash TL, Vazey EM, Rinker JA, Lebonville CL, O'Hara K, Lopez MF, Jones SR, Grant KA, Becker HC, Mulholland PJ. Assessing negative affect in mice during abstinence from alcohol drinking: Limitations and future challenges. Alcohol. 2022 Feb 15; 100:41-56. PMID: 35181404.
      Citations:    
    3. Brundage JN, Mason CP, Wadsworth HA, Finuf CS, Nelson JJ, Ronström PJW, Jones SR, Siciliano CA, Steffensen SC, Yorgason JT. Regional and sex differences in spontaneous striatal dopamine transmission. J Neurochem. 2022 Mar; 160(6):598-612. PMID: 34265080.
      Citations:    
    4. George BE, Barth SH, Kuiper LB, Holleran KM, Lacy RT, Raab-Graham KF, Jones SR. Enhanced heroin self-administration and distinct dopamine adaptations in female rats. Neuropsychopharmacology. 2021 May 26. PMID: 34040157.
      Citations:    
    5. Jones SR, Fordahl SC. Bingeing on High-Fat Food Enhances Evoked Dopamine Release and Reduces Dopamine Uptake in the Nucleus Accumbens. Obesity (Silver Spring). 2021 Apr; 29(4):721-730. PMID: 33660412.
      Citations:    
    6. Holleran KM, Rose JH, Fordahl SC, Benton KC, Rohr KE, Gasser PJ, Jones SR. Organic cation transporter 3 and the dopamine transporter differentially regulate catecholamine uptake in the basolateral amygdala and nucleus accumbens. Eur J Neurosci. 2020 12; 52(11):4546-4562. PMID: 32725894.
      Citations:    
    7. Godfrey JR, Pincus M, Kovacs-Balint Z, Feczko E, Earl E, Miranda-Dominguez O, Fair DA, Jones SR, Locke J, Sanchez MM, Wilson ME, Michopoulos V. Obesogenic diet-associated C-reactive protein predicts reduced central dopamine and corticostriatal functional connectivity in female rhesus monkeys. Brain Behav Immun. 2020 08; 88:166-173. PMID: 32240763.
      Citations:    
    8. Siciliano CA, Mauterer MI, Fordahl SC, Jones SR. Modulation of striatal dopamine dynamics by cocaine self-administration and amphetamine treatment in female rats. Eur J Neurosci. 2019 08; 50(4):2740-2749. PMID: 31111573.
      Citations:    
    9. Karkhanis AN, Leach AC, Yorgason JT, Uneri A, Barth S, Niere F, Alexander NJ, Weiner JL, McCool BA, Raab-Graham KF, Ferris MJ, Jones SR. Chronic Social Isolation Stress during Peri-Adolescence Alters Presynaptic Dopamine Terminal Dynamics via Augmentation in Accumbal Dopamine Availability. ACS Chem Neurosci. 2019 04 17; 10(4):2033-2044. PMID: 30284806.
      Citations:    
    10. Mauterer MI, Estave PM, Holleran KM, Jones SR. Measurement of Dopamine Using Fast Scan Cyclic Voltammetry in Rodent Brain Slices. Bio Protoc. 2018 Oct 05; 8(19):e2473. PMID: 34532508.
      Citations:    
    11. Schmidt KT, Makhijani VH, Boyt KM, Cogan ES, Pati D, Pina MM, Bravo IM, Locke JL, Jones SR, Besheer J, McElligott ZA. Stress-Induced Alterations of Norepinephrine Release in the Bed Nucleus of the Stria Terminalis of Mice. ACS Chem Neurosci. 2019 04 17; 10(4):1908-1914. PMID: 30252438.
      Citations:    
    12. McGuier NS, Rinker JA, Cannady R, Fulmer DB, Jones SR, Hoffman M, Mulholland PJ. Identification and validation of midbrain Kcnq4 regulation of heavy alcohol consumption in rodents. Neuropharmacology. 2018 08; 138:10-19. PMID: 29775679.
      Citations:    
    13. Siciliano CA, Karkhanis AN, Holleran KM, Melchior JR, Jones SR. Cross-Species Alterations in Synaptic Dopamine Regulation After Chronic Alcohol Exposure. Handb Exp Pharmacol. 2018; 248:213-238. PMID: 29675581.
      Citations:    
    14. Siciliano CA, Saha K, Calipari ES, Fordahl SC, Chen R, Khoshbouei H, Jones SR. Amphetamine Reverses Escalated Cocaine Intake via Restoration of Dopamine Transporter Conformation. J Neurosci. 2018 01 10; 38(2):484-497. PMID: 29175958.
      Citations:    
    15. Melchior JR, Jones SR. Chronic ethanol exposure increases inhibition of optically targeted phasic dopamine release in the nucleus accumbens core and medial shell ex vivo. Mol Cell Neurosci. 2017 12; 85:93-104. PMID: 28942046.
      Citations:    
    16. Karkhanis A, Holleran KM, Jones SR. Dynorphin/Kappa Opioid Receptor Signaling in Preclinical Models of Alcohol, Drug, and Food Addiction. Int Rev Neurobiol. 2017; 136:53-88. PMID: 29056156.
      Citations:    
    17. Siciliano CA, McIntosh JM, Jones SR, Ferris MJ. a6ß2 subunit containing nicotinic acetylcholine receptors exert opposing actions on rapid dopamine signaling in the nucleus accumbens of rats with high-versus low-response to novelty. Neuropharmacology. 2017 Nov; 126:281-291. PMID: 28666811.
      Citations:    
    18. Siciliano CA, Jones SR. Cocaine Potency at the Dopamine Transporter Tracks Discrete Motivational States During Cocaine Self-Administration. Neuropsychopharmacology. 2017 Aug; 42(9):1893-1904. PMID: 28139678.
      Citations:    
    19. Fordahl SC, Jones SR. High-Fat-Diet-Induced Deficits in Dopamine Terminal Function Are Reversed by Restoring Insulin Signaling. ACS Chem Neurosci. 2017 02 15; 8(2):290-299. PMID: 27966885.
      Citations:    
    20. Brodnik ZD, Ferris MJ, Jones SR, España RA. Reinforcing Doses of Intravenous Cocaine Produce Only Modest Dopamine Uptake Inhibition. ACS Chem Neurosci. 2017 02 15; 8(2):281-289. PMID: 27936579.
      Citations:    
    21. Brust TF, Morgenweck J, Kim SA, Rose JH, Locke JL, Schmid CL, Zhou L, Stahl EL, Cameron MD, Scarry SM, Aubé J, Jones SR, Martin TJ, Bohn LM. Biased agonists of the kappa opioid receptor suppress pain and itch without causing sedation or dysphoria. Sci Signal. 2016 11 29; 9(456):ra117. PMID: 27899527.
      Citations:    
    22. McGinnis MM, Siciliano CA, Jones SR. Dopamine D3 autoreceptor inhibition enhances cocaine potency at the dopamine transporter. J Neurochem. 2016 09; 138(6):821-9. PMID: 27393374.
      Citations:    
    23. Shaw JK, Ferris MJ, Locke JL, Brodnik ZD, Jones SR, España RA. Hypocretin/orexin knock-out mice display disrupted behavioral and dopamine responses to cocaine. Addict Biol. 2017 Nov; 22(6):1695-1705. PMID: 27480648.
      Citations:    
    24. Rose JH, Karkhanis AN, Steiniger-Brach B, Jones SR. Distinct Effects of Nalmefene on Dopamine Uptake Rates and Kappa Opioid Receptor Activity in the Nucleus Accumbens Following Chronic Intermittent Ethanol Exposure. Int J Mol Sci. 2016 Jul 27; 17(8). PMID: 27472317.
      Citations:    
    25. Siciliano CA, Fordahl SC, Jones SR. Cocaine Self-Administration Produces Long-Lasting Alterations in Dopamine Transporter Responses to Cocaine. J Neurosci. 2016 07 27; 36(30):7807-16. PMID: 27466327.
      Citations:    
    26. Karkhanis AN, Huggins KN, Rose JH, Jones SR. Switch from excitatory to inhibitory actions of ethanol on dopamine levels after chronic exposure: Role of kappa opioid receptors. Neuropharmacology. 2016 11; 110(Pt A):190-197. PMID: 27450094.
      Citations:    
    27. Karkhanis AN, Beveridge TJ, Blough BE, Jones SR, Ferris MJ. The individual and combined effects of phenmetrazine and mgluR2/3 agonist LY379268 on the motivation to self-administer cocaine. Drug Alcohol Depend. 2016 Sep 01; 166:51-60. PMID: 27394931.
      Citations:    
    28. Siciliano CA, Locke JL, Mathews TA, Lopez MF, Becker HC, Jones SR. Dopamine synthesis in alcohol drinking-prone and -resistant mouse strains. Alcohol. 2017 Feb; 58:25-32. PMID: 27425261.
      Citations:    
    29. Fordahl SC, Locke JL, Jones SR. High fat diet augments amphetamine sensitization in mice: Role of feeding pattern, obesity, and dopamine terminal changes. Neuropharmacology. 2016 10; 109:170-182. PMID: 27267686.
      Citations:    
    30. Salvatore MF, Calipari ES, Jones SR. Regulation of Tyrosine Hydroxylase Expression and Phosphorylation in Dopamine Transporter-Deficient Mice. ACS Chem Neurosci. 2016 07 20; 7(7):941-51. PMID: 27124386.
      Citations:    
    31. Butler TR, Karkhanis AN, Jones SR, Weiner JL. Adolescent Social Isolation as a Model of Heightened Vulnerability to Comorbid Alcoholism and Anxiety Disorders. Alcohol Clin Exp Res. 2016 06; 40(6):1202-14. PMID: 27154240.
      Citations:    
    32. Rose JH, Karkhanis AN, Chen R, Gioia D, Lopez MF, Becker HC, McCool BA, Jones SR. Supersensitive Kappa Opioid Receptors Promotes Ethanol Withdrawal-Related Behaviors and Reduce Dopamine Signaling in the Nucleus Accumbens. Int J Neuropsychopharmacol. 2016 05; 19(5). PMID: 26625893.
      Citations:    
    33. Silverstein-Metzler MG, Shively CA, Clarkson TB, Appt SE, Carr JJ, Kritchevsky SB, Jones SR, Register TC. Sertraline inhibits increases in body fat and carbohydrate dysregulation in adult female cynomolgus monkeys. Psychoneuroendocrinology. 2016 06; 68:29-38. PMID: 26939086.
      Citations:    
    34. Siciliano CA, Calipari ES, Yorgason JT, Lovinger DM, Mateo Y, Jimenez VA, Helms CM, Grant KA, Jones SR. Increased presynaptic regulation of dopamine neurotransmission in the nucleus accumbens core following chronic ethanol self-administration in female macaques. Psychopharmacology (Berl). 2016 Apr; 233(8):1435-43. PMID: 26892380.
      Citations:    
    35. Sunwook K, Nussbaum MA, Quandt SA, Laurienti PJ, Arcury TA. Effects of Lifetime Occupational Pesticide Exposure on Postural Control Among Farmworkers and Non-Farmworkers. J Occup Environ Med. 2016 Feb; 58(2):133-9. PMID: 26860203.
      Citations:    
    36. Siciliano CA, Calipari ES, Yorgason JT, Mateo Y, Helms CM, Lovinger DM, Grant KA, Jones SR. Chronic ethanol self-administration in macaques shifts dopamine feedback inhibition to predominantly D2 receptors in nucleus accumbens core. Drug Alcohol Depend. 2016 Jan 01; 158:159-63. PMID: 26627912.
      Citations:    
    37. Yorgason JT, Calipari ES, Ferris MJ, Karkhanis AN, Fordahl SC, Weiner JL, Jones SR. Social isolation rearing increases dopamine uptake and psychostimulant potency in the striatum. Neuropharmacology. 2016 Feb; 101:471-9. PMID: 26525189.
      Citations:    
    38. Sun H, Calipari ES, Beveridge TJ, Jones SR, Chen R. The brain gene expression profile of dopamine D2/D3 receptors and associated signaling proteins following amphetamine self-administration. Neuroscience. 2015 Oct 29; 307:253-61. PMID: 26321241.
      Citations:    
    39. Pleil KE, Lowery-Gionta EG, Crowley NA, Li C, Marcinkiewcz CA, Rose JH, McCall NM, Maldonado-Devincci AM, Morrow AL, Jones SR, Kash TL. Effects of chronic ethanol exposure on neuronal function in the prefrontal cortex and extended amygdala. Neuropharmacology. 2015 Dec; 99:735-49. PMID: 26188147.
      Citations:    
    40. Cervera-Juanes R, Wilhem LJ, Park B, Lee R, Locke J, Helms C, Gonzales S, Wand G, Jones SR, Grant KA, Ferguson B. MAOA expression predicts vulnerability for alcohol use. Mol Psychiatry. 2016 Apr; 21(4):472-9. PMID: 26148813.
      Citations:    
    41. Siciliano CA, Ferris MJ, Jones SR. Cocaine self-administration disrupts mesolimbic dopamine circuit function and attenuates dopaminergic responsiveness to cocaine. Eur J Neurosci. 2015 Aug; 42(4):2091-6. PMID: 26037018.
      Citations:    
    42. Willard SL, Uberseder B, Clark A, Daunais JB, Johnston WD, Neely D, Massey A, Williamson JD, Kraft RA, Bourland JD, Jones SR, Shively CA. Long term sertraline effects on neural structures in depressed and nondepressed adult female nonhuman primates. Neuropharmacology. 2015 Dec; 99:369-78. PMID: 26116816.
      Citations:    
    43. Melchior JR, Ferris MJ, Stuber GD, Riddle DR, Jones SR. Optogenetic versus electrical stimulation of dopamine terminals in the nucleus accumbens reveals local modulation of presynaptic release. J Neurochem. 2015 09; 134(5):833-44. PMID: 26011081.
      Citations:    
    44. Karkhanis AN, Alexander NJ, McCool BA, Weiner JL, Jones SR. Chronic social isolation during adolescence augments catecholamine response to acute ethanol in the basolateral amygdala. Synapse. 2015 Aug; 69(8):385-95. PMID: 25963724.
      Citations:    
    45. Siciliano CA, Calipari ES, Cuzon Carlson VC, Helms CM, Lovinger DM, Grant KA, Jones SR. Voluntary ethanol intake predicts ?-opioid receptor supersensitivity and regionally distinct dopaminergic adaptations in macaques. J Neurosci. 2015 Apr 15; 35(15):5959-68. PMID: 25878269.
      Citations:    
    46. Ferris MJ, Calipari ES, Rose JH, Siciliano CA, Sun H, Chen R, Jones SR. A Single Amphetamine Infusion Reverses Deficits in Dopamine Nerve-Terminal Function Caused by a History of Cocaine Self-Administration. Neuropsychopharmacology. 2015 Jul; 40(8):1826-36. PMID: 25689882.
      Citations:    
    47. Karkhanis AN, Rose JH, Huggins KN, Konstantopoulos JK, Jones SR. Chronic intermittent ethanol exposure reduces presynaptic dopamine neurotransmission in the mouse nucleus accumbens. Drug Alcohol Depend. 2015 May 01; 150:24-30. PMID: 25765483.
      Citations:    
    48. Luderman KD, Chen R, Ferris MJ, Jones SR, Gnegy ME. Protein kinase C beta regulates the D2-like dopamine autoreceptor. Neuropharmacology. 2015 Feb; 89:335-41. PMID: 25446677.
      Citations:    
    49. Richardson JR, Taylor MM, Shalat SL, Guillot TS, Caudle WM, Hossain MM, Mathews TA, Jones SR, Cory-Slechta DA, Miller GW. Developmental pesticide exposure reproduces features of attention deficit hyperactivity disorder. FASEB J. 2015 May; 29(5):1960-72. PMID: 25630971.
      Citations:    
    50. Siciliano CA, Calipari ES, Ferris MJ, Jones SR. Adaptations of presynaptic dopamine terminals induced by psychostimulant self-administration. ACS Chem Neurosci. 2015 Jan 21; 6(1):27-36. PMID: 25491345.
      Citations:    
    51. Calipari ES, Ferris MJ, Siciliano CA, Jones SR. Differential influence of dopamine transport rate on the potencies of cocaine, amphetamine, and methylphenidate. ACS Chem Neurosci. 2015 Jan 21; 6(1):155-62. PMID: 25474655.
      Citations:    
    52. Yorgason JT, Rose JH, McIntosh JM, Ferris MJ, Jones SR. Greater ethanol inhibition of presynaptic dopamine release in C57BL/6J than DBA/2J mice: Role of nicotinic acetylcholine receptors. Neuroscience. 2015 Jan 22; 284:854-864. PMID: 25451295.
      Citations:    
    53. Karkhanis AN, Locke JL, McCool BA, Weiner JL, Jones SR. Social isolation rearing increases nucleus accumbens dopamine and norepinephrine responses to acute ethanol in adulthood. Alcohol Clin Exp Res. 2014 Nov; 38(11):2770-9. PMID: 25421514.
      Citations:    
    54. Calipari ES, Siciliano CA, Zimmer BA, Jones SR. Brief intermittent cocaine self-administration and abstinence sensitizes cocaine effects on the dopamine transporter and increases drug seeking. Neuropsychopharmacology. 2015 Feb; 40(3):728-35. PMID: 25212486.
      Citations:    
    55. Siciliano CA, Calipari ES, Jones SR. Amphetamine potency varies with dopamine uptake rate across striatal subregions. J Neurochem. 2014 Nov; 131(3):348-55. PMID: 24988947.
      Citations:    
    56. Ferris MJ, España RA, Locke JL, Konstantopoulos JK, Rose JH, Chen R, Jones SR. Dopamine transporters govern diurnal variation in extracellular dopamine tone. Proc Natl Acad Sci U S A. 2014 Jul 01; 111(26):E2751-9. PMID: 24979798.
      Citations:    
    57. Diaz MR, Jotty K, Locke JL, Jones SR, Valenzuela CF. Moderate Alcohol Exposure during the Rat Equivalent to the Third Trimester of Human Pregnancy Alters Regulation of GABAA Receptor-Mediated Synaptic Transmission by Dopamine in the Basolateral Amygdala. Front Pediatr. 2014; 2:46. PMID: 24904907.
      Citations:    
    58. Daigle TL, Ferris MJ, Gainetdinov RR, Sotnikova TD, Urs NM, Jones SR, Caron MG. Selective deletion of GRK2 alters psychostimulant-induced behaviors and dopamine neurotransmission. Neuropsychopharmacology. 2014 Sep; 39(10):2450-62. PMID: 24776686.
      Citations:    
    59. Ferris MJ, Milenkovic M, Liu S, Mielnik CA, Beerepoot P, John CE, España RA, Sotnikova TD, Gainetdinov RR, Borgland SL, Jones SR, Ramsey AJ. Sustained N-methyl-d-aspartate receptor hypofunction remodels the dopamine system and impairs phasic signaling. Eur J Neurosci. 2014 Jul; 40(1):2255-63. PMID: 24754704.
      Citations:    
    60. Siciliano CA, Calipari ES, Ferris MJ, Jones SR. Biphasic mechanisms of amphetamine action at the dopamine terminal. J Neurosci. 2014 Apr 16; 34(16):5575-82. PMID: 24741047.
      Citations:    
    61. Calipari ES, Jones SR. Sensitized nucleus accumbens dopamine terminal responses to methylphenidate and dopamine transporter releasers after intermittent-access self-administration. Neuropharmacology. 2014 Jul; 82:1-10. PMID: 24632529.
      Citations:    
    62. Calipari ES, Ferris MJ, Siciliano CA, Zimmer BA, Jones SR. Intermittent cocaine self-administration produces sensitization of stimulant effects at the dopamine transporter. J Pharmacol Exp Ther. 2014 May; 349(2):192-8. PMID: 24566123.
      Citations:    
    63. Calipari ES, Sun H, Eldeeb K, Luessen DJ, Feng X, Howlett AC, Jones SR, Chen R. Amphetamine self-administration attenuates dopamine D2 autoreceptor function. Neuropsychopharmacology. 2014 Jul; 39(8):1833-42. PMID: 24513972.
      Citations:    
    64. Rose JH, Calipari ES, Mathews TA, Jones SR. Greater ethanol-induced locomotor activation in DBA/2J versus C57BL/6J mice is not predicted by presynaptic striatal dopamine dynamics. PLoS One. 2013; 8(12):e83852. PMID: 24349553.
      Citations:    
    65. Calipari ES, Ferris MJ, Jones SR. Extended access of cocaine self-administration results in tolerance to the dopamine-elevating and locomotor-stimulating effects of cocaine. J Neurochem. 2014 Jan; 128(2):224-32. PMID: 24102293.
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    66. Calipari ES, Beveridge TJ, Jones SR, Porrino LJ. Withdrawal from extended-access cocaine self-administration results in dysregulated functional activity and altered locomotor activity in rats. Eur J Neurosci. 2013 Dec; 38(12):3749-57. PMID: 24118121.
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    67. Yorgason JT, Ferris MJ, Steffensen SC, Jones SR. Frequency-dependent effects of ethanol on dopamine release in the nucleus accumbens. Alcohol Clin Exp Res. 2014 Feb; 38(2):438-47. PMID: 24117706.
      Citations:    
    68. Ferris MJ, Calipari ES, Melchior JR, Roberts DC, España RA, Jones SR. Paradoxical tolerance to cocaine after initial supersensitivity in drug-use-prone animals. Eur J Neurosci. 2013 Aug; 38(4):2628-36. PMID: 23725404.
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    69. Calipari ES, Ferris MJ, Zimmer BA, Roberts DC, Jones SR. Temporal pattern of cocaine intake determines tolerance vs sensitization of cocaine effects at the dopamine transporter. Neuropsychopharmacology. 2013 Nov; 38(12):2385-92. PMID: 23719505.
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    70. Ferris MJ, Calipari ES, Yorgason JT, Jones SR. Examining the complex regulation and drug-induced plasticity of dopamine release and uptake using voltammetry in brain slices. ACS Chem Neurosci. 2013 May 15; 4(5):693-703. PMID: 23581570.
      Citations:    
    71. Yorgason JT, España RA, Konstantopoulos JK, Weiner JL, Jones SR. Enduring increases in anxiety-like behavior and rapid nucleus accumbens dopamine signaling in socially isolated rats. Eur J Neurosci. 2013 Mar; 37(6):1022-31. PMID: 23294165.
      Citations:    
    72. Calipari ES, Ferris MJ, Salahpour A, Caron MG, Jones SR. Methylphenidate amplifies the potency and reinforcing effects of amphetamines by increasing dopamine transporter expression. Nat Commun. 2013; 4:2720. PMID: 24193139.
      Citations:    
    73. Espana RA, Jones SR. Presynaptic dopamine modulation by stimulant self-administration. Front Biosci (Schol Ed). 2013 Jan 01; 5:261-76. PMID: 23277050.
      Citations:    
    74. Calipari ES, Huggins KN, Mathews TA, Jones SR. Conserved dorsal-ventral gradient of dopamine release and uptake rate in mice, rats and rhesus macaques. Neurochem Int. 2012 Dec; 61(7):986-91. PMID: 22819794.
      Citations:    
    75. Brookshire BR, Jones SR. Chronic methylphenidate administration in mice produces depressive-like behaviors and altered responses to fluoxetine. Synapse. 2012 Sep; 66(9):844-7. PMID: 22588965.
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    76. Calipari ES, Ferris MJ, Melchior JR, Bermejo K, Salahpour A, Roberts DC, Jones SR. Methylphenidate and cocaine self-administration produce distinct dopamine terminal alterations. Addict Biol. 2014 Mar; 19(2):145-55. PMID: 22458761.
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    77. Huggins KN, Mathews TA, Locke JL, Szeliga KT, Friedman DP, Bennett AJ, Jones SR. Effects of early life stress on drinking and serotonin system activity in rhesus macaques: 5-hydroxyindoleacetic acid in cerebrospinal fluid predicts brain tissue levels. Alcohol. 2012 Jun; 46(4):371-6. PMID: 22445804.
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    78. Oleson EB, Ferris MJ, España RA, Harp J, Jones SR. Effects of the histamine H1 receptor antagonist and benztropine analog diphenylpyraline on dopamine uptake, locomotion and reward. Eur J Pharmacol. 2012 May 15; 683(1-3):161-5. PMID: 22445882.
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    79. Ferris MJ, Calipari ES, Mateo Y, Melchior JR, Roberts DC, Jones SR. Cocaine self-administration produces pharmacodynamic tolerance: differential effects on the potency of dopamine transporter blockers, releasers, and methylphenidate. Neuropsychopharmacology. 2012 Jun; 37(7):1708-16. PMID: 22395730.
      Citations:    
    80. Yorgason JT, Jones SR, España RA. Low and high affinity dopamine transporter inhibitors block dopamine uptake within 5 sec of intravenous injection. Neuroscience. 2011 May 19; 182:125-32. PMID: 21402130.
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    81. Yorgason JT, España RA, Jones SR. Demon voltammetry and analysis software: analysis of cocaine-induced alterations in dopamine signaling using multiple kinetic measures. J Neurosci Methods. 2011 Nov 15; 202(2):158-64. PMID: 21392532.
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    82. Ferris MJ, Mateo Y, Roberts DC, Jones SR. Cocaine-insensitive dopamine transporters with intact substrate transport produced by self-administration. Biol Psychiatry. 2011 Feb 01; 69(3):201-7. PMID: 20801429.
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    83. España RA, Melchior JR, Roberts DC, Jones SR. Hypocretin 1/orexin A in the ventral tegmental area enhances dopamine responses to cocaine and promotes cocaine self-administration. Psychopharmacology (Berl). 2011 Mar; 214(2):415-26. PMID: 20959967.
      Citations:    
    84. España RA, Oleson EB, Locke JL, Brookshire BR, Roberts DC, Jones SR. The hypocretin-orexin system regulates cocaine self-administration via actions on the mesolimbic dopamine system. Eur J Neurosci. 2010 Jan; 31(2):336-48. PMID: 20039943.
      Citations:    
    85. Oleson EB, Salek J, Bonin KD, Jones SR, Budygin EA. Real-time voltammetric detection of cocaine-induced dopamine changes in the striatum of freely moving mice. Neurosci Lett. 2009 Dec 25; 467(2):144-6. PMID: 19822192.
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    86. Mathews TA, Brookshire BR, Budygin EA, Hamre K, Goldowitz D, Jones SR. Ethanol-induced hyperactivity is associated with hypodopaminergia in the 22-TNJ ENU-mutated mouse. Alcohol. 2009 Sep; 43(6):421-31. PMID: 19801272.
      Citations:    
    87. Brookshire BR, Jones SR. Direct and indirect 5-HT receptor agonists produce gender-specific effects on locomotor and vertical activities in C57 BL/6J mice. Pharmacol Biochem Behav. 2009 Nov; 94(1):194-203. PMID: 19698737.
      Citations:    
    88. España RA, Roberts DC, Jones SR. Short-acting cocaine and long-acting GBR-12909 both elicit rapid dopamine uptake inhibition following intravenous delivery. Neuroscience. 2008 Jul 31; 155(1):250-7. PMID: 18597947.
      Citations:    
    89. Schroeder FA, Penta KL, Matevossian A, Jones SR, Konradi C, Tapper AR, Akbarian S. Drug-induced activation of dopamine D(1) receptor signaling and inhibition of class I/II histone deacetylase induce chromatin remodeling in reward circuitry and modulate cocaine-related behaviors. Neuropsychopharmacology. 2008 Nov; 33(12):2981-92. PMID: 18288092.
      Citations:    
    90. Lack CM, Jones SR, Roberts DC. Increased breakpoints on a progressive ratio schedule reinforced by IV cocaine are associated with reduced locomotor activation and reduced dopamine efflux in nucleus accumbens shell in rats. Psychopharmacology (Berl). 2008 Jan; 195(4):517-25. PMID: 17879088.
      Citations:    
    91. Budygin EA, Oleson EB, Mathews TA, Läck AK, Diaz MR, McCool BA, Jones SR. Effects of chronic alcohol exposure on dopamine uptake in rat nucleus accumbens and caudate putamen. Psychopharmacology (Berl). 2007 Sep; 193(4):495-501. PMID: 17492432.
      Citations:    
    92. John CE, Jones SR. Voltammetric characterization of the effect of monoamine uptake inhibitors and releasers on dopamine and serotonin uptake in mouse caudate-putamen and substantia nigra slices. Neuropharmacology. 2007 Jun; 52(8):1596-605. PMID: 17459426.
      Citations:    
    93. Mathews TA, John CE, Lapa GB, Budygin EA, Jones SR. No role of the dopamine transporter in acute ethanol effects on striatal dopamine dynamics. Synapse. 2006 Sep 15; 60(4):288-94. PMID: 16786536.
      Citations:    
    94. Jones SR, Mathews TA, Budygin EA. Effect of moderate ethanol dose on dopamine uptake in rat nucleus accumbens in vivo. Synapse. 2006 Sep 01; 60(3):251-5. PMID: 16752364.
      Citations:    
    95. John CE, Jones SR. Exocytotic release of dopamine in ventral tegmental area slices from C57BL/6 and dopamine transporter knockout mice. Neurochem Int. 2006 Dec; 49(8):737-45. PMID: 16901588.
      Citations:    
    96. Goldowitz D, Matthews DB, Hamre KM, Mittleman G, Chesler EJ, Becker HC, Lopez MF, Jones SR, Mathews TA, Miles MF, Kerns R, Grant KA. Progress in using mouse inbred strains, consomics, and mutants to identify genes related to stress, anxiety, and alcohol phenotypes. Alcohol Clin Exp Res. 2006 Jun; 30(6):1066-78. PMID: 16737467.
      Citations:    
    97. John CE, Budygin EA, Mateo Y, Jones SR. Neurochemical characterization of the release and uptake of dopamine in ventral tegmental area and serotonin in substantia nigra of the mouse. J Neurochem. 2006 Jan; 96(1):267-82. PMID: 16300629.
      Citations:    
    98. Lapa GB, Byrd GD, Lapa AA, Budygin EA, Childers SR, Jones SR, Harp JJ. The synthesis and biological evaluation of dopamine transporter inhibiting activity of substituted diphenylmethoxypiperidines. Bioorg Med Chem Lett. 2005 Nov 15; 15(22):4915-8. PMID: 16165350.
      Citations:    
    99. Erikson KM, John CE, Jones SR, Aschner M. Manganese accumulation in striatum of mice exposed to toxic doses is dependent upon a functional dopamine transporter. Environ Toxicol Pharmacol. 2005 Nov; 20(3):390-4. PMID: 21783617.
      Citations:    
    100. Budygin EA, Mathews TA, Lapa GB, Jones SR. Local effects of acute ethanol on dopamine neurotransmission in the ventral striatum in C57BL/6 mice. Eur J Pharmacol. 2005 Oct 31; 523(1-3):40-5. PMID: 16226738.
      Citations:    
    101. Mateo Y, Lack CM, Morgan D, Roberts DC, Jones SR. Reduced dopamine terminal function and insensitivity to cocaine following cocaine binge self-administration and deprivation. Neuropsychopharmacology. 2005 Aug; 30(8):1455-63. PMID: 15702135.
      Citations:    
    102. Mateo Y, Budygin EA, John CE, Banks ML, Jones SR. Voltammetric assessment of dopamine clearance in the absence of the dopamine transporter: no contribution of other transporters in core or shell of nucleus accumbens. J Neurosci Methods. 2004 Dec 30; 140(1-2):183-7. PMID: 15589348.
      Citations:    
    103. Lapa GB, Mathews TA, Harp J, Budygin EA, Jones SR. Diphenylpyraline, a histamine H1 receptor antagonist, has psychostimulant properties. Eur J Pharmacol. 2005 Jan 04; 506(3):237-40. PMID: 15627433.
      Citations:    
    104. Mateo Y, Budygin EA, Morgan D, Roberts DC, Jones SR. Fast onset of dopamine uptake inhibition by intravenous cocaine. Eur J Neurosci. 2004 Nov; 20(10):2838-42. PMID: 15548229.
      Citations:    
    105. Sotnikova TD, Budygin EA, Jones SR, Dykstra LA, Caron MG, Gainetdinov RR. Dopamine transporter-dependent and -independent actions of trace amine beta-phenylethylamine. J Neurochem. 2004 Oct; 91(2):362-73. PMID: 15447669.
      Citations:    
    106. Budygin EA, Brodie MS, Sotnikova TD, Mateo Y, John CE, Cyr M, Gainetdinov RR, Jones SR. Dissociation of rewarding and dopamine transporter-mediated properties of amphetamine. Proc Natl Acad Sci U S A. 2004 May 18; 101(20):7781-6. PMID: 15136721.
      Citations:    
    107. Mateo Y, Budygin EA, John CE, Jones SR. Role of serotonin in cocaine effects in mice with reduced dopamine transporter function. Proc Natl Acad Sci U S A. 2004 Jan 06; 101(1):372-7. PMID: 14691264.
      Citations:    
    108. Budygin EA, John CE, Mateo Y, Daunais JB, Friedman DP, Grant KA, Jones SR. Chronic ethanol exposure alters presynaptic dopamine function in the striatum of monkeys: a preliminary study. Synapse. 2003 Dec 01; 50(3):266-8. PMID: 14515345.
      Citations:    
    109. Mottola DM, Kilts JD, Lewis MM, Connery HS, Walker QD, Jones SR, Booth RG, Hyslop DK, Piercey M, Wightman RM, Lawler CP, Nichols DE, Mailman RB. Functional selectivity of dopamine receptor agonists. I. Selective activation of postsynaptic dopamine D2 receptors linked to adenylate cyclase. J Pharmacol Exp Ther. 2002 Jun; 301(3):1166-78. PMID: 12023552.
      Citations:    
    110. Budygin EA, John CE, Mateo Y, Jones SR. Lack of cocaine effect on dopamine clearance in the core and shell of the nucleus accumbens of dopamine transporter knock-out mice. J Neurosci. 2002 May 15; 22(10):RC222. PMID: 12006604.
      Citations:    
    111. Budygin EA, Phillips PE, Wightman RM, Jones SR. Terminal effects of ethanol on dopamine dynamics in rat nucleus accumbens: an in vitro voltammetric study. Synapse. 2001 Nov; 42(2):77-9. PMID: 11574942.
      Citations:    
    112. Zhuang X, Oosting RS, Jones SR, Gainetdinov RR, Miller GW, Caron MG, Hen R. Hyperactivity and impaired response habituation in hyperdopaminergic mice. Proc Natl Acad Sci U S A. 2001 Feb 13; 98(4):1982-7. PMID: 11172062.
      Citations:    
    113. Xu F, Gainetdinov RR, Wetsel WC, Jones SR, Bohn LM, Miller GW, Wang YM, Caron MG. Mice lacking the norepinephrine transporter are supersensitive to psychostimulants. Nat Neurosci. 2000 May; 3(5):465-71. PMID: 10769386.
      Citations:    
    114. Bliziotes M, McLoughlin S, Gunness M, Fumagalli F, Jones SR, Caron MG. Bone histomorphometric and biomechanical abnormalities in mice homozygous for deletion of the dopamine transporter gene. Bone. 2000 Jan; 26(1):15-9. PMID: 10617152.
      Citations:    
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