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Ryan T. Hughes MD

TitleAssistant Professor
InstitutionWake Forest School of Medicine
DepartmentRadiation Oncology
Address
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    Collapse Biography 
    Collapse education and training
    Wake Forest University, Winston Salem, NCBS05/2011Biology
    Wake Forest Baptist Medical Center, Winston Salem, NCMD06/2015Medicine
    Wake Forest Baptist Medical Center, Winston Salem, NC06/2016Medicine-Preliminary Intern
    Wake Forest Baptist Medical Center, Winston Salem, NCChief Resident06/2020Radiation Oncology
    Collapse awards and honors
    2022Publication Award, Radiation Oncology Institute
    2023Educator of the Year Award, Association of Residents in Radiation Oncology

    Collapse Overview 

    Collapse Research 
    Collapse research activities and funding
    3P30CA012197-49S1     (MESA, RUBEN A.)Feb 1, 1997 - Jan 31, 2027
    NIH
    National Cancer Institute (NCI) Early Career Cancer Clinical Investigator Award (ECIA) P30 Administrative Supplement
    Role: Co-Investigator
    3UG1CA189824-09S2     (LESSER, GLENN J ;WEAVER, KATHRYN ELIZABETH)Aug 1, 2014 - Jul 31, 2025
    NIH
    Clinical Studies NCORP Boot Camp Program for Early-Career Investigators
    Role: Co-Investigator
    5UG1CA189824-07     (LESSER, GLENN J)Aug 1, 2014 - Jul 31, 2025
    NIH
    Wake Forest NCORP Research Base
    Role: Co-Investigator
         (Greven KM)Jan 1, 2018 - Dec 31, 2019
    Wake Forest University School of Medicine Department of Pathology
    Human papillomavirus-associated squamous cell carcinoma of the larynx: a retrospective analysis of incidence and clinical outcomes
    Role: Co-investigator
         (Hughes RT)Jun 1, 2019 - Dec 31, 2021
    Lung Cancer Institute
    Exhaled breath analysis to assess pneumonitis development after chemoradiotherapy for Stage III NSCLC
    Role: Principal Investigator

    Collapse Featured Content 
    Collapse Twitter

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Hughes RT, Snavely AC, Dressler EV, Tegeler CH, Nightingale CL, Furdui CM, Soto Pantoja DR, Register TC, Weaver KE, Lesser GJ. Carotid ultrasound to identify head and neck cancer survivors with high cardiovascular risk after radiation therapy: rationale and design of a prospective, cross-sectional pilot study. Future Oncol. 2024 Sep 04; 1-11. PMID: 39230469.
      Citations:    
    2. Park SH, Peters M, Aguayo C, Farris MK, Hughes RT, Moore J, Munley MT, Reno KE, Gardin J, Cline JM, Peters CM, Willey JS. Secretory factors released from high dose radiation-activated osteoclasts increase the expression level of pain-associated neuropeptides in sensory neuronal cultures. Res Sq. 2024 Jul 01. PMID: 39011106.
      Citations:    
    3. Razavian NB, Hughes RT. If the Disease Was Excised, Radiation Therapy Is Ill-Advised. Int J Radiat Oncol Biol Phys. 2024 Jul 01; 119(3):719-720. PMID: 38851271.
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    4. Liu F, Farris MK, Ververs JD, Hughes RT, Munley MT. Histology-driven hypofractionated radiation therapy schemes for early-stage lung adenocarcinoma and squamous cell carcinoma. Radiother Oncol. 2024 Jun; 195:110257. PMID: 38548113.
      Citations:    
    5. Hughes RT, Razavian NB, Shenker RF, Kelsey CR, Smith S, D'Agostino RB, Winkfield KM. Radiotherapy for Advanced Hodgkin Lymphoma with Initial Bulk: A Combined Analysis of Two Randomized Trials. Adv Radiat Oncol. 2024 May; 9(5):101450. PMID: 38550369.
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    6. Winkfield KM, Hughes RT, Brown DR, Clohessy RM, Holder RC, Russell GB, Rejeski AF, Burnett LR. Randomized Pilot Study of a Keratin-based Topical Cream for Radiation Dermatitis in Breast Cancer Patients. Technol Cancer Res Treat. 2024; 23:15330338231222137. PMID: 38186361.
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    7. Shenker RF, Razavian NB, Lanier CM, Hughes RT. Prognostication methods for patients treated with palliative radiotherapy: a narrative review. Ann Palliat Med. 2024 Mar; 13(2):322-333. PMID: 38124472.
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    8. Razavian NB, Shenker RF, Farris MK, Hughes RT. In Reply to Takiar and Beadle. Int J Radiat Oncol Biol Phys. 2023 Dec 01; 117(5):1299-1301. PMID: 37980147.
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    9. Shenker RF, Razavian NB, D'Agostino RB, Mowery YM, Brizel DM, Hughes RT. Clinical outcomes of oropharyngeal squamous cell carcinoma stratified by human papillomavirus subtype: A systematic review and meta-analysis. Oral Oncol. 2024 Jan; 148:106644. PMID: 38006690.
      Citations:    
    10. Pena J, Cull D, Strowd LC, Vaidya R, Seegars MB, Ahn C, Winkfield KM, Hughes RT. Response and local control in patients treated with low-dose radiotherapy for tumoral mycosis fungoides. Leuk Lymphoma. 2023 Dec; 64(13):2202-2207. PMID: 37671707.
      Citations:    
    11. Hughes RT, Levine BJ, May N, Shenker RF, Yang JH, Lanier CM, Frizzell BA, Greven KM, Waltonen JD. Survival and Swallowing Function after Primary Radiotherapy versus Transoral Robotic Surgery for Human Papillomavirus-Associated Oropharyngeal Squamous Cell Carcinoma. ORL J Otorhinolaryngol Relat Spec. 2023; 85(5):284-293. PMID: 37647863.
      Citations:    
    12. Razavian NB, Shenker RF, D'Agostino RB, Hughes RT. Association of ipsilateral radiation therapy with contralateral lymph node failure in patients with squamous cell carcinoma of the oral cavity: A systematic review and meta-analysis. Head Neck. 2023 Aug; 45(8):1967-1974. PMID: 37246617.
      Citations:    
    13. Hughes RT, Gebeyehu RR, Kalada JM, Lycan TW, Frizzell BA, Kinney RD, D'Agostino RB, Bunch PM, Triozzi P, Zhang W, Furdui CM, Porosnicu M. Quad-shot-immunotherapy: quad-shot radiotherapy with pembrolizumab for advanced/recurrent head and neck cancer. Future Oncol. 2023 May 18. PMID: 37199326.
      Citations:    
    14. Razavian NB, D'Agostino RB, Shenker RF, Hughes RT. Intensity-Modulated Radiation Therapy for Early-Stage Squamous Cell Carcinoma of the Glottic Larynx: A Systematic Review and Meta-Analysis. Int J Radiat Oncol Biol Phys. 2023 Nov 01; 117(3):652-663. PMID: 37150263.
      Citations:    
    15. Farris MK, Razavian NB, Hughes RT, Ververs JD, Snavely AC, Leyrer CM, Tye KE, Allen LF, Pacholke HD, Weaver KE, Bunch PM, Chan MD, Clark H, Puthoff G, Farris JC, Steber CR, Wentworth S, Levine BJ, Nightingale CL, Ponnatapura J. Bridging the Communication Gaps: A Prospective Single-Arm Pilot Study Testing the Feasibility of Interdisciplinary Radiotherapy Planning in Locally Advanced Lung Cancer. Acad Radiol. 2023 Feb 07. PMID: 36759296.
      Citations:    
    16. Razavian NB, D'Agostino RB, Steber CR, Helis CA, Hughes RT. Association of Unilateral Radiotherapy With Contralateral Lymph Node Failure Among Patients With Squamous Cell Carcinoma of the Tonsil: A Systematic Review and Meta-analysis. JAMA Netw Open. 2023 Feb 01; 6(2):e2255209. PMID: 36753275.
      Citations:    
    17. Abdulhaleem M, Ruiz J, O'Neill S, Hughes RT, Qasem S, Strowd RE, Furdui C, Watabe K, Miller LD, Debinski W, Tatter S, Metheny-Barlow L, White JJ, Lee J, McTyre ER, Laxton A, Chan MD, Su J, Soike MH. Collagen deposition within brain metastases is associated with leptomeningeal failure after ?cavity-directed radiosurgery. Neurooncol Adv. 2023; 5(1):vdac186. PMID: 36789023.
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    18. Lanier CM, Johnson AG, Razavian NB, Farris JC, Hughes RT. Skeletal-Related Events After Surgery With or Without Radiotherapy for Bone Metastases to Weight-Bearing Bones. Cureus. 2022 Dec; 14(12):e32778. PMID: 36686116.
      Citations:    
    19. Farris JC, Razavian NB, Farris MK, Ververs JD, Frizzell BA, Leyrer CM, Allen LF, Greven KM, Hughes RT. Head and neck radiotherapy quality assurance conference for dedicated review of delineated targets and organs at risk: results of a prospective study. J Radiother Pract. 2023; 22. PMID: 38292763.
      Citations:    
    20. Farris JC, Hughes RT, Razavian NB, Pearce JB, Snavely AC, Chan MD, Steber CR, Leyrer CM, Bunch PM, Willey JS, Farris MK. Brain Metastasis Incidence and Patterns of Presentation After Definitive Treatment of Locally Advanced Non-Small Cell Lung Cancer: A Potential Argument for Brain Magnetic Resonance Imaging Surveillance. Adv Radiat Oncol. 2023; 8(3):101058. PMID: 37273925.
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    21. Hughes RT, Ip EH, Urbanic JJ, Hu JJ, Weaver KE, Lively MO, Winkfield KM, Shaw EG, Diaz LB, Brown DR, Strasser J, Sears JD, Lesser GJ. Smoking and Radiation-induced Skin Injury: Analysis of a Multiracial, Multiethnic Prospective Clinical Trial. Clin Breast Cancer. 2022 Dec; 22(8):762-770. PMID: 36216768.
      Citations:    
    22. Farris JC, Steber CR, Black PJ, Chan MD, Ververs JD, Cramer CK, Browne JD, Waltonen JD, Sullivan CA, Patwa HS, Laxton AW, Tatter SB, Frizzell BA, Porosnicu M, Lycan TW, Greven KM, Hughes RT. Intensity-modulated radiotherapy with planned Gamma Knife radiosurgery boost for head and neck cancer with extensive disease in proximity to critical structures. Head Neck. 2022 Nov; 44(11):2571-2578. PMID: 36047613.
      Citations:    
    23. Patel Z, Schroeder JA, Bunch PM, Evans JK, Steber CR, Johnson AG, Farris JC, Hughes RT. Discordance Between Oncology Clinician-Perceived and Radiologist-Intended Meaning of the Postradiotherapy Positron Emission Tomography/Computed Tomography Freeform Report for Head and Neck Cancer. JAMA Otolaryngol Head Neck Surg. 2022 Aug 18. PMID: 35980655.
      Citations:    
    24. Farris JC, Johnson AG, Carriere PP, Patel ZA, Nagatsuka M, Farris MK, Hughes RT. Palliative Appropriateness Criteria: A Pragmatic Method to Evaluate the Suitability of Palliative Radiotherapy Fractionation. J Palliat Med. 2023 Jan; 26(1):67-72. PMID: 35881861.
      Citations:    
    25. Steber CR, Russell GB, Rush MC, Shenker RF, Frizzell BA, Greven KM, Hughes RT. Timing of radiotherapy and chemotherapy start for patients treated with definitive concurrent chemoradiation for head and neck cancer. Acta Oncol. 2022 Aug; 61(8):987-993. PMID: 35695175.
      Citations:    
    26. Hughes RT, Tye KE, Ververs JD, O'Connell NS, Helis CA, Steber CR, Johnson AG, Chan MD, Farris MK. Virtual Radiation Oncology Peer Review is Associated with Decreased Engagement and Limited Case Discussion: Analysis of a Prospective Database Before and During the COVID-19 Pandemic. Int J Radiat Oncol Biol Phys. 2022 Apr 27. PMID: 35489631.
      Citations:    
    27. Johansson ED, Hughes RT, Meegalla NT, Porosnicu M, Patwa HS, Lack CM, Bunch PM. Neck Imaging Reporting and Data System Category 3 on Surveillance Computed Tomography: Incidence, Biopsy Rate, and Predictive Performance in Head and Neck Squamous Cell Carcinoma. Laryngoscope. 2022 Jan 19. PMID: 35043989.
      Citations:    
    28. Nightingale C, Sterba KR, Levine B, Tooze JA, Greven K, Frizzell B, Hughes RT, Snavely A, Lesser GJ, Norona S, Pleasant K, Weaver KE. Feasibility and Acceptability of a Multi-Modality Self-Management Intervention for Head and Neck Cancer Caregivers: A Pilot Randomized Trial. Integr Cancer Ther. 2022; 21:15347354221098984. PMID: 35575280.
      Citations:    
    29. Lanier CM, Lecompte M, Glenn C, Hughes RT, Isom S, Jenkins W, Cramer CK, Chan M, Tatter SB, Laxton AW. A Single-Institution Retrospective Study of Patients Treated With Laser-Interstitial Thermal Therapy for Radiation Necrosis of the Brain. Cureus. 2021 Nov; 13(11):e19967. PMID: 34984127.
      Citations:    
    30. Burcher KM, Lantz JW, Gavrila E, Abreu A, Burcher JT, Faucheux AT, Xie A, Jackson C, Song AH, Hughes RT, Lycan T, Bunch PM, Furdui CM, Topaloglu U, D'Agostino RB, Zhang W, Porosnicu M. Relationship between Tumor Mutational Burden, PD-L1, Patient Characteristics, and Response to Immune Checkpoint Inhibitors in Head and Neck Squamous Cell Carcinoma. Cancers (Basel). 2021 Nov 16; 13(22). PMID: 34830888.
      Citations:    
    31. Farris JC, Hughes RT, Steber CR, Craven TE, Frizzell BA. Patient assessment of lower urinary tract symptoms using the international prostate symptom score following low-dose-rate prostate brachytherapy. Brachytherapy. 2021 Nov-Dec; 20(6):1107-1113. PMID: 34353749.
      Citations:    
    32. Hughes RT, Porosnicu M, Levine BJ, Lycan TW, Shenker RF, Frizzell BA, Greven KM. Chemoradiotherapy with high-dose cisplatin compared with weekly cisplatin for locally advanced head and neck squamous cell carcinoma. J Med Imaging Radiat Oncol. 2021 Jul 26. PMID: 34309212.
      Citations:    
    33. Bunch PM, Meegalla NT, Abualruz AR, Frizzell BA, Patwa HS, Porosnicu M, Williams DW, Aiken AH, Hughes RT. Initial Referring Physician and Radiologist Experience with Neck Imaging Reporting and Data System. Laryngoscope. 2021 Jul 17. PMID: 34272871.
      Citations:    
    34. Johnson AG, Soike MH, Farris MK, Hughes RT. Efficacy and Survival after Palliative Radiotherapy for Malignant Pulmonary Obstruction. J Palliat Med. 2022 01; 25(1):46-53. PMID: 34255568.
      Citations:    
    35. Steber CR, Hughes RT, Urbanic J, Clark H, Petty WJ, Blackstock AW, Farris MK. Long-Term Outcomes from a Phase 2 Trial of Radiofrequency Ablation Combined with External Beam Radiation Therapy for Patients with Inoperable Non-Small Cell Lung Cancer. Int J Radiat Oncol Biol Phys. 2021 Apr 28. PMID: 33932531.
      Citations:    
    36. Steber CR, Ponnatapura J, Hughes RT, Farris MK. Rapid Development of Clinically Symptomatic Radiation Recall Pneumonitis Immediately Following COVID-19 Vaccination. Cureus. 2021 Apr 05; 13(4):e14303. PMID: 33968515.
      Citations:    
    37. Bunch PM, Patwa HS, Hughes RT, Porosnicu M, Waltonen JD. Patient Selection for Transoral Robotic Surgery (TORS) in Oropharyngeal Squamous Cell Carcinoma: What the Surgeon Wants to Know. Top Magn Reson Imaging. 2021 Apr 01; 30(2):117-130. PMID: 33828063.
      Citations:    
    38. Hughes RT, Steber CR, Jacobson TJ, Farris MK. Impact of dose to lung outside the planning target volume on distant metastasis or progression after SBRT for early-stage non-small cell lung cancer. Radiother Oncol. 2021 Mar 09; 159:28-32. PMID: 33711410.
      Citations:    
    39. Bunch PM, Hughes RT, White EP, Sachs JR, Frizzell BA, Lack CM. The Pharyngolaryngeal Venous Plexus: A Potential Pitfall in Surveillance Imaging of the Neck. AJNR Am J Neuroradiol. 2021 May; 42(5):938-944. PMID: 33664114.
      Citations:    
    40. Steber CR, Hughes RT, Soike MH, Helis CA, Nieto K, Jacobson T, Nagatsuka M, McGinnis HS, Leyrer CM, Farris MK. Stereotactic body radiotherapy for synchronous early stage non-small cell lung cancer. Acta Oncol. 2021 May; 60(5):605-612. PMID: 33645424.
      Citations:    
    41. Shenker RF, May NH, Waltonen JD, Yang JP, O'Neill SS, Frizzell BA, Greven KM, Hughes RT. Comparing Outcomes for Patients with Human Papillomavirus (HPV) Type 16 versus Other High-Risk HPV Types in Oropharyngeal Squamous Cell Carcinoma. Head Neck Pathol. 2021 Feb 22. PMID: 33616854.
      Citations:    
    42. Hughes RT, Farris J, Steber C, Frizzell BA, Greven KM. Perineural Invasion As the Sole Pathologic Risk Factor After Surgical Resection for Head and Neck Squamous Cell Carcinoma. Cureus. 2021 Feb 03; 13(2):e13094. PMID: 33692913.
      Citations:    
    43. Steber C, Hughes RT, McTyre ER, Soike M, Farris M, Levine BJ, Pasche B, Levine E, Blackstock AW. Cisplatin/5-Fluorouracil (5-FU) Versus Carboplatin/Paclitaxel Chemoradiotherapy as Definitive or Pre-Operative Treatment of Esophageal Cancer. Cureus. 2021 Jan 08; 13(1):e12574. PMID: 33575139.
      Citations:    
    44. Burnett LR, Hughes RT, Rejeski AF, Moffatt LT, Shupp JW, Christy RJ, Winkfield KM. Review of the Terminology Describing Ionizing Radiation-Induced Skin Injury: A Case for Standardization. Technol Cancer Res Treat. 2021 Jan-Dec; 20:15330338211039681. PMID: 34613833.
      Citations:    
    45. Helis CA, Hughes RT, Chan MD. In Reply to the Letter to the Editor Regarding "Stereotactic Radiosurgery for Atypical and Anaplastic Meningiomas". World Neurosurg. 2020 12; 144:325. PMID: 33227867.
      Citations:    
    46. Steber C, Farris J, Hughes RT, Helis CA, Naal T, Kim-Shapiro JW, Jacobson T, Farris MK. Malignant Pericardial Mesothelioma Treated Using Volumetric Modulated Arc Therapy With a Simultaneous Integrated Boost. Adv Radiat Oncol. 2021 Jan-Feb; 6(1):100562. PMID: 33490725.
      Citations:    
    47. Steber CR, Hughes RT, Soike MH, Jacobson T, Helis CA, Farris JC, Farris MK. Five- Versus Ten-Fraction Regimens of Stereotactic Body Radiation Therapy for Primary and Metastatic NSCLC. Clin Lung Cancer. 2021 Jan; 22(1):e122-e131. PMID: 33046359.
      Citations:    
    48. Helis CA, Hughes RT, Cramer CK, Tatter SB, Laxton AW, Bourland JD, Munley MT, Chan MD. Stereotactic Radiosurgery for Atypical and Anaplastic Meningiomas. World Neurosurg. 2020 12; 144:e53-e61. PMID: 32758657.
      Citations:    
    49. Helis CA, Hughes RT, Nieto K, Ufondu A, Daugherty EC, Farris MK. Adrenal SBRT: a multi-institutional review of treatment outcomes and toxicity. Clin Exp Metastasis. 2020 10; 37(5):585-592. PMID: 32700208.
      Citations:    
    50. Helis CA, Hughes RT, Glenn CW, Lanier CM, Masters AH, Dohm A, Ahmed T, Ruiz J, Triozzi P, Gondal H, Cramer CK, Tatter SB, Laxton AW, Xing F, Lo HW, Su J, Watabe K, Wang G, Whitlow CT, Chan MD. Predictors of Adverse Radiation Effect in Brain Metastasis Patients Treated With Stereotactic Radiosurgery and Immune Checkpoint Inhibitor Therapy. Int J Radiat Oncol Biol Phys. 2020 09 01; 108(1):295-303. PMID: 32615262.
      Citations:    
    51. Helis CA, Hughes RT, Munley MT, Bourland JD, Jacobson T, Lucas JT, Cramer CK, Tatter SB, Laxton AW, Chan MD. Results of a third Gamma Knife radiosurgery for trigeminal neuralgia. J Neurosurg. 2020 Apr 24; 1-7. PMID: 32330887.
      Citations:    
    52. Farris MK, Helis CA, Hughes RT, LeCompte MC, Borg AM, Nieto K, Munley MT, Willey JS. Bench to Bedside: Animal Models of Radiation Induced Musculoskeletal Toxicity. Cancers (Basel). 2020 Feb 12; 12(2). PMID: 32059447.
      Citations:    
    53. LeCompte MC, Hughes RT, Farris M, Masters A, Soike MH, Lanier C, Glenn C, Cramer CK, Watabe K, Su J, Ruiz J, Whitlow CT, Wang G, Laxton AW, Tatter SB, Chan MD. Impact of brain metastasis velocity on neurologic death for brain metastasis patients experiencing distant brain failure after initial stereotactic radiosurgery. J Neurooncol. 2020 Jan; 146(2):285-292. PMID: 31894518.
      Citations:    
    54. Soike MH, Logue J, Qasem S, Hughes RT, McTyre E, Su J, Triozzi P, Bendandi M, Lo HW, Ahmed T, O'Neill SS, Debinski W, Pasche B, Watabe K, Miller LD, Chan MD, Ruiz J. CD138 plasma cells may predict brain metastasis recurrence following resection and stereotactic radiosurgery. Sci Rep. 2019 10 07; 9(1):14385. PMID: 31591443.
      Citations:    
    55. Hughes RT, Beuerlein WJ, O'Neill SS, Porosnicu M, Lycan TW, Waltonen JD, Frizzell BA, Greven KM. Human papillomavirus-associated squamous cell carcinoma of the larynx or hypopharynx: Clinical outcomes and implications for laryngeal preservation. Oral Oncol. 2019 11; 98:20-27. PMID: 31536842.
      Citations:    
    56. Hughes RT, McTyre ER, LeCompte M, Cramer CK, Munley MT, Laxton AW, Tatter SB, Ruiz J, Pasche B, Watabe K, Chan MD. Clinical Outcomes of Upfront Stereotactic Radiosurgery Alone for Patients With 5 to 15 Brain Metastases. Neurosurgery. 2019 08 01; 85(2):257-263. PMID: 29982831.
      Citations:    
    57. Rosas S, Hughes RT, Farris M, Lee H, McTyre ER, Plate JF, Shi L, Emory CL, Blackstock AW, Kerr BA, Willey JS. Cartilage oligomeric matrix protein in patients with osteoarthritis is independently associated with metastatic disease in prostate cancer. Oncotarget. 2019 Jul 30; 10(46):4776-4785. PMID: 31413818.
      Citations:    
    58. Farris MK, Wheless WH, Hughes RT, Soike MH, Masters AH, Helis CA, Chan MD, Cramer CK, Ruiz J, Lycan T, Petty WJ, Ahmed T, Leyrer CM, Blackstock AW. Limited-Stage Small Cell Lung Cancer: Is Prophylactic Cranial Irradiation Necessary? Pract Radiat Oncol. 2019 Nov; 9(6):e599-e607. PMID: 31271904.
      Citations:    
    59. Hughes RT, Helis CA, Soike MH, Levine BJ, Farris M, Blackstock AW. Moderately Hypofractionated Radiotherapy Alone for Stage I-IIB Non-small Cell Lung Cancer. Cureus. 2019 Jun 22; 11(6):e4969. PMID: 31453041.
      Citations:    
    60. Hughes RT, Masters AH, McTyre ER, Farris MK, Chung C, Page BR, Kleinberg LR, Hepel J, Contessa JN, Chiang V, Ruiz J, Watabe K, Su J, Fiveash JB, Braunstein S, Chao S, Attia A, Ayala-Peacock DN, Chan MD. Initial SRS for Patients With 5 to 15 Brain Metastases: Results of a Multi-Institutional Experience. Int J Radiat Oncol Biol Phys. 2019 08 01; 104(5):1091-1098. PMID: 30959122.
      Citations:    
    61. Masters AH, Hughes RT, Strowd L, Lamar Z, Winkfield KM. Efficacy of low-dose radiotherapy for refractory mycosis fungoides of the face. JAAD Case Rep. 2019 Apr; 5(4):348-351. PMID: 31008164.
      Citations:    
    62. Soike MH, Hughes RT, Farris M, McTyre ER, Cramer CK, Bourland JD, Chan MD. Does Stereotactic Radiosurgery Have a Role in the Management of Patients Presenting With 4 or More Brain Metastases? Neurosurgery. 2019 03 01; 84(3):558-566. PMID: 29860451.
      Citations:    
    63. Lanier CM, Hughes R, Ahmed T, LeCompte M, Masters AH, Petty WJ, Ruiz J, Triozzi P, Su J, O'Neill S, Watabe K, Cramer CK, Laxton AW, Tatter SB, Wang G, Whitlow C, Chan MD. Immunotherapy is associated with improved survival and decreased neurologic death after SRS for brain metastases from lung and melanoma primaries. Neurooncol Pract. 2019 Sep; 6(5):402-409. PMID: 31555455.
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    64. Nagatsuka M, Hughes RT, Shenker RF, Frizzell BA, Greven KM. Omitting Elective Irradiation of the Contralateral Retropharyngeal Nodes in Oropharyngeal Squamous Cell Carcinoma Treated with Intensity-modulated Radiotherapy. Cureus. 2019 Jan 04; 11(1):e3825. PMID: 30868038.
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    65. Hughes RT, Soike MH, Prajapati S, Lin AQ, Ververs JD, Masters AH, Helis CA, Blackstock AW, Farris MK. Stereotactic body radiotherapy for an isolated splenic metastasis from ovarian carcinoma. J Radiosurg SBRT. 2019; 6(2):161-163. PMID: 31641553.
      Citations:    
    66. Dohm AE, Hughes R, Wheless W, Lecompte M, Lanier C, Ruiz J, Watabe K, Xing F, Su J, Cramer C, Laxton A, Tatter S, Chan MD. Surgical resection and postoperative radiosurgery versus staged radiosurgery for large brain metastases. J Neurooncol. 2018 Dec; 140(3):749-756. PMID: 30367382.
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    67. Farris M, Hughes RT, Lamar Z, Soike MH, Menke JR, Ohgami RS, Winkfield K. Histiocytic Sarcoma Associated With Follicular Lymphoma: Evidence for Dramatic Response With Rituximab and Bendamustine Alone and a Review of the Literature. Clin Lymphoma Myeloma Leuk. 2019 01; 19(1):e1-e8. PMID: 30396823.
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    68. Petty WJ, Urbanic JJ, Ahmed T, Hughes R, Levine B, Rusthoven K, Papagikos M, Ruiz JR, Lally BE, Chan M, Clark H, D'Agostino RB, Blackstock AW. Long-Term Outcomes of a Phase 2 Trial of Chemotherapy With Consolidative Radiation Therapy for Oligometastatic Non-Small Cell Lung Cancer. Int J Radiat Oncol Biol Phys. 2018 11 01; 102(3):527-535. PMID: 30003996.
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    69. Soike MH, McTyre ER, Hughes RT, Farris M, Cramer CK, LeCompte MC, Lanier CM, Ruiz J, Su J, Watabe K, Bourland JD, Munley MT, O'Neill S, Laxton AW, Tatter SB, Chan MD. Initial brain metastasis velocity: does the rate at which cancers first seed the brain affect outcomes? J Neurooncol. 2018 Sep; 139(2):461-467. PMID: 29740743.
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    70. LeCompte MC, McTyre ER, Strowd RE, Lanier C, Soike MH, Hughes RT, Masters AH, Cramer CK, Farris M, Ruiz J, Watabe K, Laxton AW, Tatter SB, Winkfield KM, Chan MD. Impact of diabetes mellitus on outcomes in patients with brain metastasis treated with stereotactic radiosurgery. J Radiosurg SBRT. 2018; 5(4):285-291. PMID: 30538889.
      Citations:    
    71. Shenker RF, Hughes RT, McTyre ER, Lanier C, Lo HW, Metheny-Barlow L, Su J, Thomas A, Brown DR, Avery T, Pasche B, Cramer CK, Laxton AW, Tatter SB, Watabe K, Chan MD. Potential prognostic markers for survival and neurologic death in patients with breast cancer brain metastases who receive upfront SRS alone. J Radiosurg SBRT. 2018; 5(4):277-283. PMID: 30538888.
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    72. Lanier CM, McTyre E, LeCompte M, Cramer CK, Hughes R, Watabe K, Lo HW, O'Neill S, Munley MT, Laxton AW, Tatter SB, Ruiz J, Chan MD. The number of prior lines of systemic therapy as a prognostic factor for patients with brain metastases treated with stereotactic radiosurgery: Results of a large single institution retrospective analysis. Clin Neurol Neurosurg. 2018 02; 165:24-28. PMID: 29289917.
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    73. Farris M, McTyre ER, Cramer CK, Hughes R, Randolph DM, Ayala-Peacock DN, Bourland JD, Ruiz J, Watabe K, Laxton AW, Tatter SB, Zhou X, Chan MD. Brain Metastasis Velocity: A Novel Prognostic Metric Predictive of Overall Survival and Freedom From Whole-Brain Radiation Therapy After Distant Brain Failure Following Upfront Radiosurgery Alone. Int J Radiat Oncol Biol Phys. 2017 05 01; 98(1):131-141. PMID: 28586952.
      Citations:    
    74. Hughes RT, Black PJ, Page BR, Lucas JT, Qasem SA, Watabe K, Ruiz J, Laxton AW, Tatter SB, Debinski W, Chan MD. Local control of brain metastases after stereotactic radiosurgery: the impact of whole brain radiotherapy and treatment paradigm. J Radiosurg SBRT. 2016; 4(2):89-96. PMID: 29296433.
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    75. Johnson AG, Ruiz J, Hughes R, Page BR, Isom S, Lucas JT, McTyre ER, Houseknecht KW, Ayala-Peacock DN, Bourland DJ, Hinson WH, Laxton AW, Tatter SB, Debinski W, Watabe K, Chan MD. Impact of systemic targeted agents on the clinical outcomes of patients with brain metastases. Oncotarget. 2015 Aug 07; 6(22):18945-55. PMID: 26087184.
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    76. Black PJ, Page BR, Lucas JT, Hughes RT, Laxton AW, Tatter SB, Munley MT, Chan MD. Factors that determine local control with gamma knife radiosurgery: The role of primary histology. J Radiosurg SBRT. 2015; 3(4):281-286. PMID: 26478823.
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