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Jeffrey R. Sachs MD

TitleAssociate Professor
InstitutionWake Forest School of Medicine
DepartmentDiagnostic Radiology
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Bunch PM, Lack CM, West TG, Tan J, Sachs JR. Accuracy of 190-keV Virtual Monoenergetic Dual-Energy CT for Determining the Presence or Absence of Intravitreal Silicone Oil. AJR Am J Roentgenol. 2021 04; 216(4):1040-1045. PMID: 33566634.
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    2. Heald CJ, Sarma A, Sachs JR, Zapadka ME, Jewett T, Bunch PM. Practical Genetics for the Neuroradiologist: Adding Value in Neurogenetic Disease. Acad Radiol. 2021 Jan 22. PMID: 33495073.
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    3. Abualruz AR, Bunch PM, Sachs JR, Zapadka ME, Lack CM. The Prevalence of Internal Auditory Canal Diverticula Is Constant Over a Large Age Range Among Patients Not Imaged for Hearing Loss. J Comput Assist Tomogr. 2021 Jan-Feb 01; 45(1):142-145. PMID: 33186176.
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    4. Aliprantis AO, Shaw CA, Griffin P, Farinola N, Railkar RA, Cao X, Liu W, Sachs JR, Swenson CJ, Lee H, Cox KS, Spellman DS, Winstead CJ, Smolenov I, Lai E, Zaks T, Espeseth AS, Panther L. A phase 1, randomized, placebo-controlled study to evaluate the safety and immunogenicity of an mRNA-based RSV prefusion F protein vaccine in healthy younger and older adults. Hum Vaccin Immunother. 2021 May 04; 17(5):1248-1261. PMID: 33121346.
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    5. Sachs JR, Gibbs KW, Swor DE, Sweeney AP, Williams DW, Burdette JH, West TG, Geer CP. COVID-19-associated Leukoencephalopathy. Radiology. 2020 09; 296(3):E184-E185. PMID: 32407258.
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    6. Durbin AP, Pierce KK, Kirkpatrick BD, Grier P, Sabundayo BP, He H, Sausser M, Russell AF, Martin J, Hyatt D, Cook M, Sachs JR, Lee AW, Wang L, Coller BA, Whitehead SS. Immunogenicity and Safety of a Tetravalent Recombinant Subunit Dengue Vaccine in Adults Previously Vaccinated with a Live Attenuated Tetravalent Dengue Vaccine: Results of a Phase-I Randomized Clinical Trial. Am J Trop Med Hyg. 2020 08; 103(2):855-863. PMID: 32394880.
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    7. Sachs JR, Lack CM, West TG, Bunch PM. Unique Characteristics of Intravitreal Silicone Oil on Dual-Energy Computed Tomography. J Comput Assist Tomogr. 2020 May/Jun; 44(3):370-373. PMID: 31929379.
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    8. Mayawala K, de Alwis DP, Sachs JR. Model Informed Drug Development: Novel Oncology Agents are Lost in Translation. Clin Cancer Res. 2019 11 15; 25(22):6564-6566. PMID: 31515459.
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    9. Sachs JR, West TG, Lack CM, Perry B, Zapadka ME. How to Incorporate Dual-Energy Computed Tomography Into Your Neuroradiology Practice: Questions and Answers. J Comput Assist Tomogr. 2018 Nov/Dec; 42(6):824-830. PMID: 30371617.
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    10. Dockendorf MF, Murthy G, Bateman KP, Kothare PA, Anderson M, Xie I, Sachs JR, Burlage R, Goldman A, Moyer M, Shah JK, Ruba R, Shipley L, Harrelson J. Leveraging Digital Health Technologies and Outpatient Sampling in Clinical Drug Development: A Phase I Exploratory Study. Clin Pharmacol Ther. 2019 01; 105(1):168-176. PMID: 29885208.
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    11. Sachs JR, Zapadka ME, Elster AD. Orbital Interstitial Fluid: Evidence of a Potential Pathway for Extracranial Cerebrospinal Fluid Absorption. J Comput Assist Tomogr. 2018 Jul/Aug; 42(4):497-501. PMID: 29489593.
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    12. Sachs JR, Zapadka ME, Popli GS, Burdette JH. Arterial spin labeling perfusion imaging demonstrates cerebral hyperperfusion in anti-NMDAR encephalitis. Radiol Case Rep. 2017 Dec; 12(4):833-837. PMID: 29484082.
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    13. Sachs JR, Mayawala K, Gadamsetty S, Kang SP, de Alwis DP. Optimal Dosing for Targeted Therapies in Oncology: Drug Development Cases Leading by Example. Clin Cancer Res. 2016 Mar 15; 22(6):1318-24. PMID: 26597302.
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    14. Hendrickson RC, Lee AY, Song Q, Liaw A, Wiener M, Paweletz CP, Seeburger JL, Li J, Meng F, Deyanova EG, Mazur MT, Settlage RE, Zhao X, Southwick K, Du Y, Holder D, Sachs JR, Laterza OF, Dallob A, Chappell DL, Snyder K, Modur V, King E, Joachim C, Bondarenko AY, Shearman M, Soper KA, Smith AD, Potter WZ, Koblan KS, Sachs AB, Yates NA. High Resolution Discovery Proteomics Reveals Candidate Disease Progression Markers of Alzheimer's Disease in Human Cerebrospinal Fluid. PLoS One. 2015; 10(8):e0135365. PMID: 26270474.
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    15. Sachs JR, Dyer RB. The "tip of the iceberg" sign. Abdom Imaging. 2015 Apr; 40(4):934-5. PMID: 25326262.
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    16. Hansen J, Kharecha P, Sato M, Masson-Delmotte V, Ackerman F, Beerling DJ, Hearty PJ, Hoegh-Guldberg O, Hsu SL, Parmesan C, Rockstrom J, Rohling EJ, Sachs J, Smith P, Steffen K, Van Susteren L, von Schuckmann K, Zachos JC. Assessing "dangerous climate change": required reduction of carbon emissions to protect young people, future generations and nature. PLoS One. 2013; 8(12):e81648. PMID: 24312568.
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    17. Edwards LS, Sachs JR, Elster AD. Skull fractures through parietal foramina: report of two cases. J Comput Assist Tomogr. 2012 May-Jun; 36(3):308-9. PMID: 22592614.
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    18. Dreiher J, Almog Y, Sprung CL, Codish S, Klein M, Einav S, Bar-Lavie Y, Singer PP, Nimrod A, Sachs J, Talmor D, Friger M, Greenberg D, Olsfanger D, Hersch M, Novack V. Temporal trends in patient characteristics and survival of intensive care admissions with sepsis: a multicenter analysis*. Crit Care Med. 2012 Mar; 40(3):855-60. PMID: 22020241.
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    19. Paweletz CP, Wiener MC, Bondarenko AY, Yates NA, Song Q, Liaw A, Lee AY, Hunt BT, Henle ES, Meng F, Sleph HF, Holahan M, Sankaranarayanan S, Simon AJ, Settlage RE, Sachs JR, Shearman M, Sachs AB, Cook JJ, Hendrickson RC. Application of an end-to-end biomarker discovery platform to identify target engagement markers in cerebrospinal fluid by high resolution differential mass spectrometry. J Proteome Res. 2010 Mar 05; 9(3):1392-401. PMID: 20095649.
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    20. Xie C, Sachs JR, Wang DH. Interdependent regulation of afferent renal nerve activity and renal function: role of transient receptor potential vanilloid type 1, neurokinin 1, and calcitonin gene-related peptide receptors. J Pharmacol Exp Ther. 2008 Jun; 325(3):751-7. PMID: 18364471.
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    21. Fancourt C, Azer K, Ramcharan SL, Bunzel M, Cambell BR, Sachs JR, Walker M. Segmentation of arterial vessel wall motion to sub-pixel resolution using M-mode ultrasound. Annu Int Conf IEEE Eng Med Biol Soc. 2008; 2008:3138-41. PMID: 19163372.
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    22. Zhu J, Wiener MC, Zhang C, Fridman A, Minch E, Lum PY, Sachs JR, Schadt EE. Increasing the power to detect causal associations by combining genotypic and expression data in segregating populations. PLoS Comput Biol. 2007 Apr 13; 3(4):e69. PMID: 17432931.
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    23. Meng F, Wiener MC, Sachs JR, Burns C, Verma P, Paweletz CP, Mazur MT, Deyanova EG, Yates NA, Hendrickson RC. Quantitative analysis of complex peptide mixtures using FTMS and differential mass spectrometry. J Am Soc Mass Spectrom. 2007 Feb; 18(2):226-33. PMID: 17070068.
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    24. Xu Q, Sachs JR, Wang TC, Schaefer WH. Quantification and identification of components in solution mixtures from 1D proton NMR spectra using singular value decomposition. Anal Chem. 2006 Oct 15; 78(20):7175-85. PMID: 17037918.
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    25. Paweletz CP, Wiener MC, Sachs JR, Meurer R, Wu MS, Wong KK, Yates NA, Hendrickson RC. Surface enhanced laser desorption ionization spectrometry reveals biomarkers for drug treatment but not dose. Proteomics. 2006 Apr; 6(7):2101-7. PMID: 16518871.
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    26. Bugianesi RM, Augustine PR, Azer K, Dufresne C, Herrington J, Kath GS, McManus OB, Napolitano CS, Rush A, Sachs J, Simpson N, Wismer MK, Kaczorowski GJ, Slaughter RS. A cell-sparing electric field stimulation technique for high-throughput screening of voltage-gated ion channels. Assay Drug Dev Technol. 2006 Feb; 4(1):21-35. PMID: 16506886.
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    27. Wiener MC, Sachs JR, Deyanova EG, Yates NA. Differential mass spectrometry: a label-free LC-MS method for finding significant differences in complex peptide and protein mixtures. Anal Chem. 2004 Oct 15; 76(20):6085-96. PMID: 15481957.
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    28. Malaney P, Spielman A, Sachs J. The malaria gap. Am J Trop Med Hyg. 2004 Aug; 71(2 Suppl):141-6. PMID: 15331830.
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    29. Buehler EC, Sachs JR, Shao K, Bagchi A, Ungar LH. The CRASSS plug-in for integrating annotation data with hierarchical clustering results. Bioinformatics. 2004 Nov 22; 20(17):3266-9. PMID: 15201188.
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    30. Kiszewski A, Mellinger A, Spielman A, Malaney P, Sachs SE, Sachs J. A global index representing the stability of malaria transmission. Am J Trop Med Hyg. 2004 May; 70(5):486-98. PMID: 15155980.
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    31. Gerhold DL, Liu F, Jiang G, Li Z, Xu J, Lu M, Sachs JR, Bagchi A, Fridman A, Holder DJ, Doebber TW, Berger J, Elbrecht A, Moller DE, Zhang BB. Gene expression profile of adipocyte differentiation and its regulation by peroxisome proliferator-activated receptor-gamma agonists. Endocrinology. 2002 Jun; 143(6):2106-18. PMID: 12021175.
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