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Heidi D. Klepin MD, MS

TitleProfessor
InstitutionWake Forest School of Medicine
DepartmentInternal Medicine, Hematology & Oncology
Address
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    Collapse Research 
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    K23AG038361     (KLEPIN, HEIDI DIANA)Sep 1, 2011 - Dec 31, 2015
    NIH
    Minimizing Physical Function Decline in Older Adults Receiving Chemotherapy
    Role: Principal Investigator
    R33AG059206     (DALE, WILLIAM)Apr 1, 2020 - Mar 31, 2023
    NIH
    Geriatric Oncology Research Infrastructure to Improve Clinical Care
    Role: Co-Principal Investigator

    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Levit LA, Singh H, Klepin HD. Cancer and aging activities at the American Society of Clinical Oncology and beyond: Reflections on the legacy of Dr. Arti Hurria. J Geriatr Oncol. 2020 03; 11(2):151-153. PMID: 31320298.
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    2. Adjei A, Buckner JC, Cathcart-Rake E, Chen H, Cohen HJ, Dao D, De Luca JE, Feliciano J, Freedman RA, Goldberg RM, Hopkins J, Hubbard J, Jatoi A, Karuturi M, Kemeny M, Kimmick GG, Klepin HD, Krok-Schoen JL, Lafky JM, Le-Rademacher JG, Li D, Lichtman SM, Maggiore R, Mandelblatt J, Morrison VA, Muss HB, Ojelabi MO, Sedrak MS, Subbiah N, Sun V, Tuttle S, VanderWalde N, Wildes T, Wong ML, Woyach J. Arti Hurria, M.D.: A tribute to her shining legacy in the Alliance for Clinical Trials in Oncology. J Geriatr Oncol. 2020 03; 11(2):179-183. PMID: 31201095.
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    3. Klepin HD, Estey E, Kadia T. More Versus Less Therapy for Older Adults With Acute Myeloid Leukemia: New Perspectives on an Old Debate. Am Soc Clin Oncol Educ Book. 2019 Jan; 39:421-432. PMID: 31099627.
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    4. Jung AY, Miljkovic I, Rubin S, Kritchevsky SB, Klepin HD, Newman AB, Cauley J, Ayonayon H, Harris TB, Murphy RA. Adherence to Cancer Prevention Guidelines among Older White and Black Adults in the Health ABC Study. Nutrients. 2019 May 03; 11(5). PMID: 31058834.
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    5. Klepin HD, Wildes TM. Geriatric Oncology: Getting Even Better with Age. J Am Geriatr Soc. 2019 05; 67(5):871-872. PMID: 31009069.
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    6. Loh KP, Tooze JA, Nicklas BJ, Kritchevsky SB, Williamson JD, Ellis LR, Powell BL, Pardee TS, Goyal NG, Klepin HD. Inflammatory biomarkers, geriatric assessment, and treatment outcomes in acute myeloid leukemia. J Geriatr Oncol. 2020 04; 11(3):410-416. PMID: 30962090.
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    7. Pal SK, Miller MJ, Agarwal N, Chang SM, Chavez-MacGregor M, Cohen E, Cole S, Dale W, Magid Diefenbach CS, Disis ML, Dreicer R, Graham DL, Henry NL, Jones J, Keedy V, Klepin HD, Markham MJ, Mittendorf EA, Rodriguez-Galindo C, Sabel MS, Schilsky RL, Sznol M, Tap WD, Westin SN, Johnson BE. Clinical Cancer Advances 2019: Annual Report on Progress Against Cancer From the American Society of Clinical Oncology. J Clin Oncol. 2019 04 01; 37(10):834-849. PMID: 30702028.
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    8. Kuhlman P, Isom S, Pardee TS, Burns C, Tawfik B, Lamar ZS, Powell BL, Klepin HD. Association between glycemic control, age, and outcomes among intensively treated patients with acute myeloid leukemia. Support Care Cancer. 2019 Aug; 27(8):2877-2884. PMID: 30554278.
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    9. Wildes TM, Tuchman SA, Klepin HD, Mikhael J, Trinkaus K, Stockerl-Goldstein K, Vij R, Colditz G. Geriatric Assessment in Older Adults with Multiple Myeloma. J Am Geriatr Soc. 2019 05; 67(5):987-991. PMID: 30548581.
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    10. Levit LA, Singh H, Klepin HD, Hurria A. Expanding the Evidence Base in Geriatric Oncology: Action Items From an FDA-ASCO Workshop. J Natl Cancer Inst. 2018 11 01; 110(11):1163-1170. PMID: 30329076.
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    11. Loh KP, Ramsdale E, Culakova E, Mendler JH, Liesveld JL, O'Dwyer KM, McHugh C, Gilles M, Lloyd T, Goodman M, Klepin HD, Mustian KM, Schnall R, Mohile SG. Novel mHealth App to Deliver Geriatric Assessment-Driven Interventions for Older Adults With Cancer: Pilot Feasibility and Usability Study. JMIR Cancer. 2018 Oct 29; 4(2):e10296. PMID: 30373733.
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    12. Loh KP, Klepin HD. Geriatric assessment in acute myeloid leukemia: current and future landscape. Blood Adv. 2018 09 25; 2(18):2418. PMID: 30254106.
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    13. Leak Bryant A, Coffman EM, Phillips B, Gray TF, Knafl GJ, Klepin HD, Wood WA, Muss H, Reeve BB. Symptoms, Mobility and Function, and Quality of Life in Adults With Acute Leukemia During Initial Hospitalization. Oncol Nurs Forum. 2018 09 01; 45(5):653-664. PMID: 30118443.
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    14. Hurria A, Soto-Perez-de-Celis E, Allred JB, Cohen HJ, Arsenyan A, Ballman K, Le-Rademacher J, Jatoi A, Filo J, Mandelblatt J, Lafky JM, Kimmick G, Klepin HD, Freedman RA, Burstein H, Gralow J, Wolff AC, Magrinat G, Barginear M, Muss H. Functional Decline and Resilience in Older Women Receiving Adjuvant Chemotherapy for Breast Cancer. J Am Geriatr Soc. 2019 05; 67(5):920-927. PMID: 30146695.
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    15. Ruiz J, Miller AA, Tooze JA, Crane S, Petty WJ, Gajra A, Klepin HD. Frailty assessment predicts toxicity during first cycle chemotherapy for advanced lung cancer regardless of chronologic age. J Geriatr Oncol. 2019 01; 10(1):48-54. PMID: 30005982.
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    16. Loh KP, Klepin HD. Geriatric Assessment in Older Patients with Acute Myeloid Leukemia. Cancers (Basel). 2018 Jul 06; 10(7). PMID: 29986389.
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    17. Loh KP, Klepin H. Incorporating Physical Function and Cognition Into Mortality Risk Assessment for Acute Myeloid Leukemia. JAMA Oncol. 2018 07 01; 4(7):1014. PMID: 29799993.
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    18. Jordan JH, Castellino SM, Meléndez GC, Klepin HD, Ellis LR, Lamar Z, Vasu S, Kitzman DW, Ntim WO, Brubaker PH, Reichek N, D'Agostino RB, Hundley WG. Left Ventricular Mass Change After Anthracycline Chemotherapy. Circ Heart Fail. 2018 07; 11(7):e004560. PMID: 29991488.
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    19. Klepin HD, Wildes TM. Fighting for the integration of geriatric principles into oncology. J Geriatr Oncol. 2018 11; 9(6):705-706. PMID: 29875080.
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    20. Soto-Perez-de-Celis E, Sun CL, Tew WP, Mohile SG, Gajra A, Klepin HD, Owusu C, Gross CP, Muss HB, Lichtman SM, Chapman AE, Cohen HJ, Dale W, Kim H, Fernandes S, Katheria V, Hurria A. Association between patient-reported hearing and visual impairments and functional, psychological, and cognitive status among older adults with cancer. Cancer. 2018 08 01; 124(15):3249-3256. PMID: 29797664.
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    21. Singh H, Hurria A, Klepin HD. Progress Through Collaboration: An ASCO and U.S. Food and Drug Administration Workshop to Improve the Evidence Base for Treating Older Adults With Cancer. Am Soc Clin Oncol Educ Book. 2018 May 23; 38:392-399. PMID: 30231338.
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    22. Mohile SG, Dale W, Somerfield MR, Schonberg MA, Boyd CM, Burhenn PS, Canin B, Cohen HJ, Holmes HM, Hopkins JO, Janelsins MC, Khorana AA, Klepin HD, Lichtman SM, Mustian KM, Tew WP, Hurria A. Practical Assessment and Management of Vulnerabilities in Older Patients Receiving Chemotherapy: ASCO Guideline for Geriatric Oncology. J Clin Oncol. 2018 08 01; 36(22):2326-2347. PMID: 29782209.
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    23. Rosko AE, Olin RL, Artz A, Wildes TM, Stauder R, Klepin HD. A call to action in hematologic disorders: A report from the ASH scientific workshop on hematology and aging. J Geriatr Oncol. 2018 07; 9(4):287-290. PMID: 29759912.
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    24. Wildes TM, Maggiore RJ, Tew WP, Smith D, Sun CL, Cohen H, Mohile SG, Gajra A, Klepin HD, Owusu C, Gross CP, Muss H, Chapman A, Lichtman SM, Katheria V, Hurria A. Factors associated with falls in older adults with cancer: a validated model from the Cancer and Aging Research Group. Support Care Cancer. 2018 Oct; 26(10):3563-3570. PMID: 29705872.
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    25. Michaelis LC, Klepin HD, Walter RB. Advancements in the management of medically less-fit and older adults with newly diagnosed acute myeloid leukemia. Expert Opin Pharmacother. 2018 06; 19(8):865-882. PMID: 29697000.
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    26. Loh KP, Lin PJ, Uth J, Quist M, Klepin H, Mustian K. Exercise for managing cancer- and treatment-related side effects in older adults. J Geriatr Oncol. 2018 07; 9(4):405-410. PMID: 29606599.
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    27. Gajra A, McCall L, Muss HB, Cohen HJ, Jatoi A, Ballman KV, Partridge AH, Sutton L, Parker BA, Magrinat G, Klepin HD, Lafky JM, Hurria A. The preference to receive chemotherapy and cancer-related outcomes in older adults with breast cancer CALGB 49907 (Alliance). J Geriatr Oncol. 2018 05; 9(3):221-227. PMID: 29602735.
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    28. Loh KP, McHugh C, Mohile SG, Mustian K, Flannery M, Klepin H, Schnall R, Culakova E, Ramsdale E. Using Information Technology in the Assessment and Monitoring of Geriatric Oncology Patients. Curr Oncol Rep. 2018 03 06; 20(3):25. PMID: 29511850.
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    29. Walter RB, Michaelis LC, Othus M, Uy GL, Radich JP, Little RF, Hita S, Saini L, Foran JM, Gerds AT, Klepin HD, Hay AE, Assouline S, Lancet JE, Couban S, Litzow MR, Stone RM, Erba HP. Intergroup LEAP trial (S1612): A randomized phase 2/3 platform trial to test novel therapeutics in medically less fit older adults with acute myeloid leukemia. Am J Hematol. 2018 02; 93(2):E49-E52. PMID: 29164656.
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    30. Abel GA, Klepin HD. Frailty and the management of hematologic malignancies. Blood. 2018 02 01; 131(5):515-524. PMID: 29141942.
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    31. Gifford AR, Lawrence JA, Baker LD, Balcueva EP, Case D, Craft S, Curtis AE, Griffin L, Groteluschen DL, Klepin HD, Lesser GJ, Messino MJ, Naughton M, Samuel TA, Rapp S, Sachs B, Sink KM, Williamson J, Shaw EG. National Institute on Aging /Alzheimer's Association criteria for Mild Cognitive Impairment applied to chemotherapy treated breast cancer survivors. J Oncol Research. 2017; 1(1). PMID: 29873324.
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    32. Ahmed T, Koch AL, Isom S, Klepin HD, Bishop JM, Ellis LR, Berenzon D, Howard D, Lyerly S, Powell BL, Pardee TS. Outcomes and changes in code status of patients with acute myeloid leukemia undergoing induction chemotherapy who were transferred to the intensive care unit. Leuk Res. 2017 11; 62:51-55. PMID: 28985622.
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    33. Maggiore RJ, Dale W, Hurria A, Klepin HD, Chapman A, Dotan E, Mohile SG, Naeim A, Gajra A, Buss MK. Hematology-Oncology Fellows' Training in Geriatrics and Geriatric Oncology: Findings From an American Society of Clinical Oncology-Sponsored National Survey. J Oncol Pract. 2017 11; 13(11):e900-e908. PMID: 28837375.
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    34. Merrill AY, Brown DR, Klepin HD, Levine EA, Howard-Mcnatt M. Outcomes after Mastectomy and Lumpectomy in Octogenarians and Nonagenarians with Early-Stage Breast Cancer. Am Surg. 2017 Aug 01; 83(8):887-894. PMID: 28822397.
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    35. Alistar A, Morris BB, Desnoyer R, Klepin HD, Hosseinzadeh K, Clark C, Cameron A, Leyendecker J, D'Agostino R, Topaloglu U, Boteju LW, Boteju AR, Shorr R, Zachar Z, Bingham PM, Ahmed T, Crane S, Shah R, Migliano JJ, Pardee TS, Miller L, Hawkins G, Jin G, Zhang W, Pasche B. Safety and tolerability of the first-in-class agent CPI-613 in combination with modified FOLFIRINOX in patients with metastatic pancreatic cancer: a single-centre, open-label, dose-escalation, phase 1 trial. Lancet Oncol. 2017 06; 18(6):770-778. PMID: 28495639.
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    36. Meléndez GC, Sukpraphrute B, D'Agostino RB, Jordan JH, Klepin HD, Ellis L, Lamar Z, Vasu S, Lesser G, Burke GL, Weaver KE, Ntim WO, Hundley WG. Frequency of Left Ventricular End-Diastolic Volume-Mediated Declines in Ejection Fraction in Patients Receiving Potentially Cardiotoxic Cancer Treatment. Am J Cardiol. 2017 05 15; 119(10):1637-1642. PMID: 28341361.
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    37. Kimmick GG, Major B, Clapp J, Sloan J, Pitcher B, Ballman K, Barginear M, Freedman RA, Artz A, Klepin HD, Lafky JM, Hopkins J, Winer E, Hudis C, Muss H, Cohen H, Jatoi A, Hurria A, Mandelblatt J. Using ePrognosis to estimate 2-year all-cause mortality in older women with breast cancer: Cancer and Leukemia Group B (CALGB) 49907 and 369901 (Alliance A151503). Breast Cancer Res Treat. 2017 Jun; 163(2):391-398. PMID: 28283904.
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    38. Uy GL, Mandrekar SJ, Laumann K, Marcucci G, Zhao W, Levis MJ, Klepin HD, Baer MR, Powell BL, Westervelt P, DeAngelo DJ, Stock W, Sanford B, Blum WG, Bloomfield CD, Stone RM, Larson RA. A phase 2 study incorporating sorafenib into the chemotherapy for older adults with FLT3-mutated acute myeloid leukemia: CALGB 11001. Blood Adv. 2017 Jan 24; 1(5):331-340. PMID: 29034366.
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    39. Hurria A, High KP, Mody L, McFarland Horne F, Escobedo M, Halter J, Hazzard W, Schmader K, Klepin H, Lee S, Makris UE, Rich MW, Rogers S, Wiggins J, Watman R, Choi J, Lundebjerg N, Zieman S. Aging, the Medical Subspecialties, and Career Development: Where We Were, Where We Are Going. J Am Geriatr Soc. 2017 Apr; 65(4):680-687. PMID: 28092400.
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    40. Randolph DM, McTyre E, Klepin H, Peiffer AM, Ayala-Peacock D, Lester S, Laxton AW, Dohm A, Tatter SB, Shaw EG, Chan MD. Impact of radiosurgical management of geriatric patients with brain metastases: Clinical and quality of life outcomes. J Radiosurg SBRT. 2017; 5(1):35-42. PMID: 29296461.
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    41. Lucas AR, Klepin HD, Porges SW, Rejeski WJ. Mindfulness-Based Movement: A Polyvagal Perspective. Integr Cancer Ther. 2018 03; 17(1):5-15. PMID: 28345362.
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    42. Maggiore RJ, Callahan KE, Tooze JA, Parker IR, Hsu T, Klepin HD. Geriatrics fellowship training and the role of geriatricians in older adult cancer care: A survey of geriatrics fellowship directors. Gerontol Geriatr Educ. 2018 Apr-Jun; 39(2):170-182. PMID: 27749199.
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    43. Klepin HD. Definition of Unfit for Standard Acute Myeloid Leukemia Therapy. Curr Hematol Malig Rep. 2016 12; 11(6):537-544. PMID: 27681539.
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    44. Freedman RA, Seisler DK, Foster JC, Sloan JA, Lafky JM, Kimmick GG, Hurria A, Cohen HJ, Winer EP, Hudis CA, Partridge AH, Carey LA, Jatoi A, Klepin HD, Citron M, Berry DA, Shulman LN, Buzdar AU, Suman VJ, Muss HB. Risk of acute myeloid leukemia and myelodysplastic syndrome among older women receiving anthracycline-based adjuvant chemotherapy for breast cancer on Modern Cooperative Group Trials (Alliance A151511). Breast Cancer Res Treat. 2017 01; 161(2):363-373. PMID: 27866278.
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    45. Peterson LL, Hurria A, Feng T, Mohile SG, Owusu C, Klepin HD, Gross CP, Lichtman SM, Gajra A, Glezerman I, Katheria V, Zavala L, Smith DD, Sun CL, Tew WP. Association between renal function and chemotherapy-related toxicity in older adults with cancer. J Geriatr Oncol. 2017 03; 8(2):96-101. PMID: 27856262.
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    46. Gajra A, Loh KP, Hurria A, Muss H, Maggiore R, Dale W, Klepin HD, Magnuson A, Lichtman SM, Williams GR, Shahrokhni A, Mohile SG. Comprehensive Geriatric Assessment-Guided Therapy Does Improve Outcomes of Older Patients With Advanced Lung Cancer. J Clin Oncol. 2016 11 20; 34(33):4047-4048. PMID: 27551131.
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    47. Klepin HD, Tooze JA, Pardee TS, Ellis LR, Berenzon D, Mihalko SL, Danhauer SC, Rao AV, Wildes TM, Williamson JD, Powell BL, Kritchevsky SB. Effect of Intensive Chemotherapy on Physical, Cognitive, and Emotional Health of Older Adults with Acute Myeloid Leukemia. J Am Geriatr Soc. 2016 10; 64(10):1988-1995. PMID: 27627675.
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    48. Cohen HJ, Smith D, Sun CL, Tew W, Mohile SG, Owusu C, Klepin HD, Gross CP, Lichtman SM, Gajra A, Filo J, Katheria V, Hurria A. Frailty as determined by a comprehensive geriatric assessment-derived deficit-accumulation index in older patients with cancer who receive chemotherapy. Cancer. 2016 Dec 15; 122(24):3865-3872. PMID: 27529755.
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    49. Presley CJ, Dotan E, Soto-Perez-de-Celis E, Jatoi A, Mohile SG, Won E, Alibhai S, Kilari D, Harrison R, Klepin HD, Wildes TM, Mustian K, Demark-Wahnefried W. Gaps in nutritional research among older adults with cancer. J Geriatr Oncol. 2016 07; 7(4):281-92. PMID: 27197919.
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    50. Sparling AS, Song E, Klepin HD, Foley KL. Is distance to chemotherapy an obstacle to adjuvant care among the N.C. Medicaid-enrolled colon cancer patients? J Gastrointest Oncol. 2016 Jun; 7(3):336-44. PMID: 27284464.
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    51. Kilari D, Soto-Perez-de-Celis E, Mohile SG, Alibhai SM, Presley CJ, Wildes TM, Klepin HD, Demark-Wahnefried W, Jatoi A, Harrison R, Won E, Mustian KM. Designing exercise clinical trials for older adults with cancer: Recommendations from 2015 Cancer and Aging Research Group NCI U13 Meeting. J Geriatr Oncol. 2016 07; 7(4):293-304. PMID: 27197916.
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    52. Hurria A, Mohile S, Gajra A, Klepin H, Muss H, Chapman A, Feng T, Smith D, Sun CL, De Glas N, Cohen HJ, Katheria V, Doan C, Zavala L, Levi A, Akiba C, Tew WP. Validation of a Prediction Tool for Chemotherapy Toxicity in Older Adults With Cancer. J Clin Oncol. 2016 07 10; 34(20):2366-71. PMID: 27185838.
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    53. Weaver KE, Leach CR, Leng X, Danhauer SC, Klepin HD, Vaughan L, Naughton M, Chlebowski RT, Vitolins MZ, Paskett E. Physical Functioning among Women 80 Years of Age and Older With and Without a Cancer History. J Gerontol A Biol Sci Med Sci. 2016 Mar; 71 Suppl 1:S23-30. PMID: 26858321.
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    54. Klepin HD. Myelodysplastic Syndromes and Acute Myeloid Leukemia in the Elderly. Clin Geriatr Med. 2016 Feb; 32(1):155-73. PMID: 26614866.
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    55. Whitlock MC, Yeboah J, Burke GL, Chen H, Klepin HD, Hundley WG. Cancer and Its Association With the Development of Coronary Artery Calcification: An Assessment From the Multi-Ethnic Study of Atherosclerosis. J Am Heart Assoc. 2015 Nov 09; 4(11). PMID: 26553214.
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    56. Tawfik B, Pardee TS, Isom S, Sliesoraitis S, Winter A, Lawrence J, Powell BL, Klepin HD. Comorbidity, age, and mortality among adults treated intensively for acute myeloid leukemia (AML). J Geriatr Oncol. 2016 Jan; 7(1):24-31. PMID: 26527394.
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    57. Izano M, Wei EK, Tai C, Swede H, Gregorich S, Harris TB, Klepin H, Satterfield S, Murphy R, Newman AB, Rubin SM, Braithwaite D. Chronic inflammation and risk of colorectal and other obesity-related cancers: The health, aging and body composition study. Int J Cancer. 2016 Mar 01; 138(5):1118-28. PMID: 26413860.
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    58. Owusu C, Cohen HJ, Feng T, Tew W, Mohile SG, Klepin HD, Gross CP, Gajra A, Lichtman SM, Hurria A. Anemia and Functional Disability in Older Adults With Cancer. J Natl Compr Canc Netw. 2015 Oct; 13(10):1233-9. PMID: 26483063.
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    59. Klepin HD. Are We Falling Short? Incorporating Falls Assessment Into Cancer Care for Older Adults. J Oncol Pract. 2015 Nov; 11(6):475-7. PMID: 26395562.
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    60. Klepin HD. Elderly acute myeloid leukemia: assessing risk. Curr Hematol Malig Rep. 2015 Jun; 10(2):118-25. PMID: 25939828.
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    61. Ahmed T, Holwerda S, Klepin HD, Isom S, Ellis LR, Lyerly S, Manuel M, Dralle S, Berenzon D, Powell BL, Pardee TS. High dose cytarabine, mitoxantrone and l-asparaginase (HAMA) salvage for relapsed or refractory acute myeloid leukemia (AML) in the elderly. Leuk Res. 2015 Sep; 39(9):945-9. PMID: 26154683.
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    62. Klepin HD. Cancer in a gerontological context. J Gerontol A Biol Sci Med Sci. 2015 Jun; 70(6):699-700. PMID: 25852091.
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    63. Gajra A, Klepin HD, Feng T, Tew WP, Mohile SG, Owusu C, Gross CP, Lichtman SM, Wildes TM, Chapman AE, Dotan E, Katheria V, Zavala L, Akiba C, Hurria A. Predictors of chemotherapy dose reduction at first cycle in patients age 65 years and older with solid tumors. J Geriatr Oncol. 2015 Mar; 6(2):133-40. PMID: 25666905.
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    64. Klepin HD, Rodin M, Hurria A. Treating older adults with cancer: geriatric perspectives. Am Soc Clin Oncol Educ Book. 2015; e544-52. PMID: 25993221.
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    65. Klepin HD. Geriatric perspective: how to assess fitness for chemotherapy in acute myeloid leukemia. Hematology Am Soc Hematol Educ Program. 2014 Dec 05; 2014(1):8-13. PMID: 25696829.
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    66. Klepin HD, Rao AV, Pardee TS. Acute myeloid leukemia and myelodysplastic syndromes in older adults. J Clin Oncol. 2014 Aug 20; 32(24):2541-52. PMID: 25071138.
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    67. Weiss Wiesel TR, Nelson CJ, Tew WP, Hardt M, Mohile SG, Owusu C, Klepin HD, Gross CP, Gajra A, Lichtman SM, Ramani R, Katheria V, Zavala L, Hurria A. The relationship between age, anxiety, and depression in older adults with cancer. Psychooncology. 2015 Jun; 24(6):712-7. PMID: 25099337.
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    68. Klepin HD, Pitcher BN, Ballman KV, Kornblith AB, Hurria A, Winer EP, Hudis C, Cohen HJ, Muss HB, Kimmick GG. Comorbidity, chemotherapy toxicity, and outcomes among older women receiving adjuvant chemotherapy for breast cancer on a clinical trial: CALGB 49907 and CALGB 361004 (alliance). J Oncol Pract. 2014 Sep; 10(5):e285-92. PMID: 25074878.
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    69. Maggiore RJ, Dale W, Gross CP, Feng T, Tew WP, Mohile SG, Owusu C, Klepin HD, Lichtman SM, Gajra A, Ramani R, Katheria V, Zavala L, Hurria A. Polypharmacy and potentially inappropriate medication use in older adults with cancer undergoing chemotherapy: effect on chemotherapy-related toxicity and hospitalization during treatment. J Am Geriatr Soc. 2014 Aug; 62(8):1505-12. PMID: 25041361.
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    70. Elliot K, Tooze JA, Geller R, Powell BL, Pardee TS, Ritchie E, Kennedy L, Callahan KE, Klepin HD. The prognostic importance of polypharmacy in older adults treated for acute myelogenous leukemia (AML). Leuk Res. 2014 Oct; 38(10):1184-90. PMID: 25127690.
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    71. Murphy RA, Bureyko TF, Miljkovic I, Cauley JA, Satterfield S, Hue TF, Klepin HD, Cummings SR, Newman AB, Harris TB. Association of total adiposity and computed tomographic measures of regional adiposity with incident cancer risk: a prospective population-based study of older adults. Appl Physiol Nutr Metab. 2014 Jun; 39(6):687-92. PMID: 24869972.
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    72. Klepin HD, Tooze JA, Song EY, Geiger AM, Foley KL. Age-Related Treatment Disparities among Medicaid Beneficiaries with Metastatic Colorectal Cancer. J Gerontol Geriatr Res. 2013 Dec 01; 2(4):134. PMID: 24501695.
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    73. Klepin HD, Geiger AM, Bandos H, Costantino JP, Rapp SR, Sink KM, Lawrence JA, Atkinson HH, Espeland MA. Cognitive factors associated with adherence to oral antiestrogen therapy: results from the cognition in the study of tamoxifen and raloxifene (Co-STAR) study. Cancer Prev Res (Phila). 2014 Jan; 7(1):161-8. PMID: 24253314.
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    74. Tawfik B, Sliesoraitis S, Lyerly S, Klepin HD, Lawrence J, Isom S, Ellis LR, Manuel M, Dralle S, Berenzon D, Powell BL, Pardee T. Efficacy of the hypomethylating agents as frontline, salvage, or consolidation therapy in adults with acute myeloid leukemia (AML). Ann Hematol. 2014 Jan; 93(1):47-55. PMID: 24149914.
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    75. Klepin HD. Predicting treatment outcomes in older patients with acute myelogenous leukemia. Clin Adv Hematol Oncol. 2013 Oct; 11(10):669-71. PMID: 24518379.
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    76. Won E, Hurria A, Feng T, Mohile S, Owusu C, Klepin HD, Gross CP, Lichtman SM, Gajra A, Tew WP. CA125 level association with chemotherapy toxicity and functional status in older women with ovarian cancer. Int J Gynecol Cancer. 2013 Jul; 23(6):1022-8. PMID: 23765208.
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    77. Mohile SG, Hardt M, Tew W, Owusu C, Klepin H, Gross C, Gajra A, Lichtman SM, Feng T, Togawa K, Ramani R, Katheria V, Hansen K, Hurria A. Toxicity of bevacizumab in combination with chemotherapy in older patients. Oncologist. 2013; 18(4):408-14. PMID: 23576485.
      Citations:    
    78. Klepin HD, Geiger AM, Tooze JA, Kritchevsky SB, Williamson JD, Pardee TS, Ellis LR, Powell BL. Geriatric assessment predicts survival for older adults receiving induction chemotherapy for acute myelogenous leukemia. Blood. 2013 May 23; 121(21):4287-94. PMID: 23550038.
      Citations:    
    79. Klepin HD, Mohile SG, Mihalko S. Exercise for older cancer patients: feasible and helpful?. Interdiscip Top Gerontol. 2013; 38:146-57. PMID: 23503523.
      Citations:    
    80. Klepin HD, Rizzieri D, Palumbo A, Magarotto V, Eichhorst B. Individualizing treatment decisions for older adults with hematologic malignancies. Am Soc Clin Oncol Educ Book. 2013; 208-19. PMID: 23714504.
      Citations:    
    81. Alibhai SM, O'Neill S, Fisher-Schlombs K, Breunis H, Brandwein JM, Timilshina N, Tomlinson GA, Klepin HD, Culos-Reed SN. A clinical trial of supervised exercise for adult inpatients with acute myeloid leukemia (AML) undergoing induction chemotherapy. Leuk Res. 2012 Oct; 36(10):1255-61. PMID: 22726923.
      Citations:    
    82. Foley KL, Song EY, Klepin H, Geiger A, Tooze J. Screening colonoscopy among colorectal cancer survivors insured by Medicaid. Am J Clin Oncol. 2012 Jun; 35(3):205-11. PMID: 21358299.
      Citations:    
    83. Maggiore RJ, Gross CP, Togawa K, Tew WP, Mohile SG, Owusu C, Klepin HD, Lichtman SM, Gajra A, Ramani R, Katheria V, Klapper SM, Hansen K, Hurria A. Use of complementary medications among older adults with cancer. Cancer. 2012 Oct 01; 118(19):4815-23. PMID: 22359348.
      Citations:    
    84. Mohile SG, Klepin HD, Rao AV. Considerations and controversies in the management of older patients with advanced cancer. Am Soc Clin Oncol Educ Book. 2012; 321-8. PMID: 24451757.
      Citations:    
    85. Lagro J, Studenski SA, Olde Rikkert MG. Predicting chemotherapy toxicity in older adults and the importance of geriatric assessment. J Clin Oncol. 2012 Feb 10; 30(5):560; author reply 561-2. PMID: 22184377.
      Citations:    
    86. Klepin HD, Geiger AM, Tooze JA, Kritchevsky SB, Williamson JD, Ellis LR, Levitan D, Pardee TS, Isom S, Powell BL. The feasibility of inpatient geriatric assessment for older adults receiving induction chemotherapy for acute myelogenous leukemia. J Am Geriatr Soc. 2011 Oct; 59(10):1837-46. PMID: 22091497.
      Citations:    
    87. Hurria A, Togawa K, Mohile SG, Owusu C, Klepin HD, Gross CP, Lichtman SM, Gajra A, Bhatia S, Katheria V, Klapper S, Hansen K, Ramani R, Lachs M, Wong FL, Tew WP. Predicting chemotherapy toxicity in older adults with cancer: a prospective multicenter study. J Clin Oncol. 2011 Sep 01; 29(25):3457-65. PMID: 21810685.
      Citations:    
    88. Foley KL, Tooze JA, Klepin HD, Song EY, Geiger AM. Adjuvant chemotherapy among medicaid-enrolled patients diagnosed with nonmetastatic colon cancer. Am J Clin Oncol. 2011 Apr; 34(2):120-4. PMID: 21499198.
      Citations:    
    89. Horton JK, Gleason JF, Klepin HD, Isom S, Fried DB, Geiger AM. Age-related disparities in the use of radiotherapy for treatment of localized soft tissue sarcoma. Cancer. 2011 Sep 01; 117(17):4033-40. PMID: 21387267.
      Citations:    
    90. Klepin HD, Danhauer SC, Tooze JA, Stott K, Daley K, Vishnevsky T, Powell BL, Mihalko SL. Exercise for older adult inpatients with acute myelogenous leukemia: A pilot study. J Geriatr Oncol. 2011 Jan; 2(1):11-17. PMID: 23843929.
      Citations:    
    91. Klepin HD, Geiger AM, Tooze JA, Newman AB, Colbert LH, Bauer DC, Satterfield S, Pavon J, Kritchevsky SB. Physical performance and subsequent disability and survival in older adults with malignancy: results from the health, aging and body composition study. J Am Geriatr Soc. 2010 Jan; 58(1):76-82. PMID: 20122042.
      Citations:    
    92. Klepin HD, Balducci L. Acute myelogenous leukemia in older adults. Oncologist. 2009 Mar; 14(3):222-32. PMID: 19282349.
      Citations:    
    93. Hartmann EL, Kitzman D, Rocco M, Leng X, Klepin H, Gordon M, Rejeski J, Berry M, Kritchevsky S. Physical function in older candidates for renal transplantation: an impaired population. Clin J Am Soc Nephrol. 2009 Mar; 4(3):588-94. PMID: 19261824.
      Citations:    
    94. Klepin H, Mohile S, Hurria A. Geriatric assessment in older patients with breast cancer. J Natl Compr Canc Netw. 2009 Feb; 7(2):226-36. PMID: 19200420.
      Citations:    
    95. Hurria A, Balducci L, Naeim A, Gross C, Mohile S, Klepin H, Tew W, Downey L, Gajra A, Owusu C, Sanati H, Suh T, Figlin R. Mentoring junior faculty in geriatric oncology: report from the Cancer and Aging Research Group. J Clin Oncol. 2008 Jul 01; 26(19):3125-7. PMID: 18591553.
      Citations:    
    96. Klepin HD, Hurd DD. Autologous transplantation in elderly patients with multiple myeloma: are we asking the right questions? Bone Marrow Transplant. 2006 Nov; 38(9):585-92. PMID: 16953209.
      Citations:    
    97. Klepin HD, McMullen KP, Lesser GJ. Esthesioneuroblastoma. Curr Treat Options Oncol. 2005 Nov; 6(6):509-18. PMID: 16242055.
      Citations:    
    98. Mendonca VM, Klepin HD, Matson SW. DNA helicases in recombination and repair: construction of a delta uvrD delta helD delta recQ mutant deficient in recombination and repair. J Bacteriol. 1995 Mar; 177(5):1326-35. PMID: 7868608.
      Citations:    
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