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John Owen MD

TitleProfessor
InstitutionWake Forest School of Medicine
DepartmentInternal Medicine, Hematology & Oncology
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Miller PJ, Farland AM, Knovich MA, Batt KM, Owen J. Successful treatment of intravenously abused oral Opana ER-induced thrombotic microangiopathy without plasma exchange. Am J Hematol. 2014 Jul; 89(7):695-7. PMID: 24668845.
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    2. Sorci-Thomas MG, Owen JS, Fulp B, Bhat S, Zhu X, Parks JS, Shah D, Jerome WG, Gerelus M, Zabalawi M, Thomas MJ. Nascent high density lipoproteins formed by ABCA1 resemble lipid rafts and are structurally organized by three apoA-I monomers. J Lipid Res. 2012 Sep; 53(9):1890-909. PMID: 22750655.
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    3. Knovich MA, Farland A, Owen J. Long-term management of acquired thrombotic thrombocytopenic purpura using serial plasma ADAMTS13 measurements. Eur J Haematol. 2012 Jun; 88(6):518-25. PMID: 22324373.
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    4. Sorci-Thomas MG, Zabalawi M, Bharadwaj MS, Wilhelm AJ, Owen JS, Asztalos BF, Bhat S, Thomas MJ. Dysfunctional HDL containing L159R ApoA-I leads to exacerbation of atherosclerosis in hyperlipidemic mice. Biochim Biophys Acta. 2012 Mar; 1821(3):502-12. PMID: 21944998.
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    5. Wilhelm AJ, Zabalawi M, Owen JS, Shah D, Grayson JM, Major AS, Bhat S, Gibbs DP, Thomas MJ, Sorci-Thomas MG. Apolipoprotein A-I modulates regulatory T cells in autoimmune LDLr-/-, ApoA-I-/- mice. J Biol Chem. 2010 Nov 12; 285(46):36158-69. PMID: 20833724.
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    6. Zhu X, Owen JS, Wilson MD, Li H, Griffiths GL, Thomas MJ, Hiltbold EM, Fessler MB, Parks JS. Macrophage ABCA1 reduces MyD88-dependent Toll-like receptor trafficking to lipid rafts by reduction of lipid raft cholesterol. J Lipid Res. 2010 Nov; 51(11):3196-206. PMID: 20650929.
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    7. Wilhelm AJ, Zabalawi M, Grayson JM, Weant AE, Major AS, Owen J, Bharadwaj M, Walzem R, Chan L, Oka K, Thomas MJ, Sorci-Thomas MG. Apolipoprotein A-I and its role in lymphocyte cholesterol homeostasis and autoimmunity. Arterioscler Thromb Vasc Biol. 2009 Jun; 29(6):843-9. PMID: 19286630.
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    8. Sane DC, Streer NP, Owen J. Myocardial necrosis in patients with thrombotic thrombocytopenic purpura: pathophysiology and rationale for specific therapy. Eur J Haematol. 2009 Feb; 82(2):83-92. PMID: 19067741.
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    9. Knovich MA, Lawson HL, Burke MH, McCoy TP, Owen J. Rapid quantitative assay of ADAMTS13 activity on an automated coagulation analyzer: clinical applications and comparison with immunoblot method. Am J Hematol. 2008 Aug; 83(8):654-6. PMID: 18528825.
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    10. Wahla AS, Ruiz J, Noureddine N, Upadhya B, Sane DC, Owen J. Myocardial infarction in thrombotic thrombocytopenic purpura: a single-center experience and literature review. Eur J Haematol. 2008 Oct; 81(4):311-6. PMID: 18616514.
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    11. Wajih N, Owen J, Wallin R. Enhanced functional recombinant factor VII production by HEK 293 cells stably transfected with VKORC1 where the gamma-carboxylase inhibitor calumenin is stably suppressed by shRNA transfection. Thromb Res. 2008; 122(3):405-10. PMID: 18177690.
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    12. Huff JD, Keung YK, Thakuri M, Beaty MW, Hurd DD, Owen J, Molnár I. Copper deficiency causes reversible myelodysplasia. Am J Hematol. 2007 Jul; 82(7):625-30. PMID: 17236184.
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    13. Owen JS, Thomas MJ, Wykle RL. Platelet-activating factor. Methods Enzymol. 2007; 434:105-16. PMID: 17954244.
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    14. Harish VC, Zhang L, Huff JD, Lawson H, Owen J. Isolated antiplasmin deficiency presenting as a spontaneous bleeding disorder in a 63-year-old man. Blood Coagul Fibrinolysis. 2006 Nov; 17(8):673-5. PMID: 17102655.
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    15. Owen JS, Bharadwaj MS, Thomas MJ, Bhat S, Samuel MP, Sorci-Thomas MG. Ratio determination of plasma wild-type and L159R apoA-I using mass spectrometry: tools for studying apoA-IFin. J Lipid Res. 2007 Jan; 48(1):226-34. PMID: 17071967.
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    16. Zhang L, Lawson HL, Harish VC, Huff JD, Knovich MA, Owen J. Creation of a recombinant peptide substrate for fluorescence resonance energy transfer-based protease assays. Anal Biochem. 2006 Nov 15; 358(2):298-300. PMID: 16876104.
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    17. Wajih N, Hutson SM, Owen J, Wallin R. Increased production of functional recombinant human clotting factor IX by baby hamster kidney cells engineered to overexpress VKORC1, the vitamin K 2,3-epoxide-reducing enzyme of the vitamin K cycle. J Biol Chem. 2005 Sep 09; 280(36):31603-7. PMID: 16030016.
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    18. Owen JS, Baker PR, O'Flaherty JT, Thomas MJ, Samuel MP, Wooten RE, Wykle RL. Stress-induced platelet-activating factor synthesis in human neutrophils. Biochim Biophys Acta. 2005 Apr 15; 1733(2-3):120-9. PMID: 15863359.
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    19. Owen JS, Wykle RL, Samuel MP, Thomas MJ. An improved assay for platelet-activating factor using HPLC-tandem mass spectrometry. J Lipid Res. 2005 Feb; 46(2):373-82. PMID: 15520455.
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    20. Keung YK, Owen J. Iron deficiency and thrombosis: literature review. Clin Appl Thromb Hemost. 2004 Oct; 10(4):387-91. PMID: 15497026.
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    21. Knovich MA, Craver K, Matulis MD, Lawson H, Owen J. Simplified assay for VWF cleaving protease (ADAMTS13) activity and inhibitor in plasma. Am J Hematol. 2004 Jul; 76(3):286-90. PMID: 15224369.
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    22. Nicol KK, Shelton BJ, Knovich MA, Owen J. Overweight individuals are at increased risk for thrombotic thrombocytopenic purpura. Am J Hematol. 2003 Nov; 74(3):170-4. PMID: 14587043.
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    23. O'Flaherty JT, Rogers LC, Chadwell BA, Owen JS, Rao A, Cramer SD, Daniel LW. 5(S)-Hydroxy-6,8,11,14-E,Z,Z,Z-eicosatetraenoate stimulates PC3 cell signaling and growth by a receptor-dependent mechanism. Cancer Res. 2002 Dec 01; 62(23):6817-9. PMID: 12460891.
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    24. Baker PR, Owen JS, Nixon AB, Thomas L, Wooten R, Daniel LW, O'Flaherty JT, Wykle RL. Regulation of platelet-activating factor synthesis in human neutrophils by MAP kinases. Biochim Biophys Acta. 2002 Oct 21; 1592(2):175-84. PMID: 12379481.
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    25. Herrington DM, Vittinghoff E, Howard TD, Major DA, Owen J, Reboussin DM, Bowden D, Bittner V, Simon JA, Grady D, Hulley SB. Factor V Leiden, hormone replacement therapy, and risk of venous thromboembolic events in women with coronary disease. Arterioscler Thromb Vasc Biol. 2002 Jun 01; 22(6):1012-7. PMID: 12067913.
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    26. Richie LI, Ebert PJ, Wu LC, Krummel MF, Owen JJ, Davis MM. Imaging synapse formation during thymocyte selection: inability of CD3zeta to form a stable central accumulation during negative selection. Immunity. 2002 Apr; 16(4):595-606. PMID: 11970882.
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