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Connection

Gregory Kucera to Humans

This is a "connection" page, showing publications Gregory Kucera has written about Humans.
Connection Strength

0.209
  1. Barnes AP, Miller BE, Kucera GL. Cyclooxygenase inhibition and hyperthermia for the potentiation of the cytotoxic response in ovarian cancer cells. Gynecol Oncol. 2007 Feb; 104(2):443-50.
    View in: PubMed
    Score: 0.015
  2. Alexander RL, Greene BT, Torti SV, Kucera GL. A novel phospholipid gemcitabine conjugate is able to bypass three drug-resistance mechanisms. Cancer Chemother Pharmacol. 2005 Jul; 56(1):15-21.
    View in: PubMed
    Score: 0.014
  3. Alexander RL, Kucera GL. Lipid nucleoside conjugates for the treatment of cancer. Curr Pharm Des. 2005; 11(9):1079-89.
    View in: PubMed
    Score: 0.013
  4. Alexander RL, Morris-Natschke SL, Ishaq KS, Fleming RA, Kucera GL. Synthesis and cytotoxic activity of two novel 1-dodecylthio-2-decyloxypropyl-3-phosphatidic acid conjugates with gemcitabine and cytosine arabinoside. J Med Chem. 2003 Sep 11; 46(19):4205-8.
    View in: PubMed
    Score: 0.012
  5. Stadheim TA, Kucera GL. c-Jun N-terminal kinase/stress-activated protein kinase (JNK/SAPK) is required for mitoxantrone- and anisomycin-induced apoptosis in HL-60 cells. Leuk Res. 2002 Jan; 26(1):55-65.
    View in: PubMed
    Score: 0.011
  6. Cai Z, Li CF, Han F, Liu C, Zhang A, Hsu CC, Peng D, Zhang X, Jin G, Rezaeian AH, Wang G, Zhang W, Pan BS, Wang CY, Wang YH, Wu SY, Yang SC, Hsu FC, D'Agostino RB, Furdui CM, Kucera GL, Parks JS, Chilton FH, Huang CY, Tsai FJ, Pasche B, Watabe K, Lin HK. Phosphorylation of PDHA by AMPK Drives TCA Cycle to Promote Cancer Metastasis. Mol Cell. 2020 10 15; 80(2):263-278.e7.
    View in: PubMed
    Score: 0.010
  7. Sexton T, Kucera GL, Levine EA, Watabe K, O'Neill SS. Optimization of Tissue Microarrays from Banked Human Formalin-Fixed Paraffin Embedded Tissues in the Cancer Research Setting. Biopreserv Biobank. 2019 Oct; 17(5):452-457.
    View in: PubMed
    Score: 0.009
  8. Song Q, Hawkins GA, Wudel L, Chou PC, Forbes E, Pullikuth AK, Liu L, Jin G, Craddock L, Topaloglu U, Kucera G, O'Neill S, Levine EA, Sun P, Watabe K, Lu Y, Alexander-Miller MA, Pasche B, Miller LD, Zhang W. Dissecting intratumoral myeloid cell plasticity by single cell RNA-seq. Cancer Med. 2019 06; 8(6):3072-3085.
    View in: PubMed
    Score: 0.009
  9. Alexander PM, Caudell DL, Kucera GL, Pladna KM, Pardee TS. The novel phospholipid mimetic KPC34 is highly active against preclinical models of Philadelphia chromosome positive acute lymphoblastic leukemia. PLoS One. 2017; 12(6):e0179798.
    View in: PubMed
    Score: 0.008
  10. Alexander P, Kucera G, Pardee TS. Improving nucleoside analogs via lipid conjugation: Is fatter any better? Crit Rev Oncol Hematol. 2016 Apr; 100:46-56.
    View in: PubMed
    Score: 0.007
  11. Yang M, Pickard AJ, Qiao X, Gueble MJ, Day CS, Kucera GL, Bierbach U. Synthesis, reactivity, and biological activity of gold(I) complexes modified with thiourea-functionalized tyrosine kinase inhibitors. Inorg Chem. 2015 Apr 06; 54(7):3316-24.
    View in: PubMed
    Score: 0.007
  12. Pickard AJ, Liu F, Bartenstein TF, Haines LG, Levine KE, Kucera GL, Bierbach U. Redesigning the DNA-targeted chromophore in platinum-acridine anticancer agents: a structure-activity relationship study. Chemistry. 2014 Dec 01; 20(49):16174-87.
    View in: PubMed
    Score: 0.007
  13. Ding S, Pickard AJ, Kucera GL, Bierbach U. Design of enzymatically cleavable prodrugs of a potent platinum-containing anticancer agent. Chemistry. 2014 Dec 01; 20(49):16164-73.
    View in: PubMed
    Score: 0.007
  14. Qiao X, Ding S, Liu F, Kucera GL, Bierbach U. Investigating the cellular fate of a DNA-targeted platinum-based anticancer agent by orthogonal double-click chemistry. J Biol Inorg Chem. 2014 Mar; 19(3):415-26.
    View in: PubMed
    Score: 0.006
  15. Ding S, Qiao X, Kucera GL, Bierbach U. Design of a platinum-acridine-endoxifen conjugate targeted at hormone-dependent breast cancer. Chem Commun (Camb). 2013 Mar 25; 49(24):2415-7.
    View in: PubMed
    Score: 0.006
  16. Ding S, Qiao X, Suryadi J, Marrs GS, Kucera GL, Bierbach U. Using fluorescent post-labeling to probe the subcellular localization of DNA-targeted platinum anticancer agents. Angew Chem Int Ed Engl. 2013 Mar 18; 52(12):3350-4.
    View in: PubMed
    Score: 0.006
  17. Ding S, Qiao X, Kucera GL, Bierbach U. Using a build-and-click approach for producing structural and functional diversity in DNA-targeted hybrid anticancer agents. J Med Chem. 2012 Nov 26; 55(22):10198-203.
    View in: PubMed
    Score: 0.006
  18. Graham LA, Suryadi J, West TK, Kucera GL, Bierbach U. Synthesis, aqueous reactivity, and biological evaluation of carboxylic acid ester-functionalized platinum-acridine hybrid anticancer agents. J Med Chem. 2012 Sep 13; 55(17):7817-27.
    View in: PubMed
    Score: 0.006
  19. Qiao X, Zeitany AE, Wright MW, Essader AS, Levine KE, Kucera GL, Bierbach U. Analysis of the DNA damage produced by a platinum-acridine antitumor agent and its effects in NCI-H460 lung cancer cells. Metallomics. 2012 Jul; 4(7):645-52.
    View in: PubMed
    Score: 0.006
  20. Eiter LC, Hall NW, Day CS, Saluta G, Kucera GL, Bierbach U. Gold(I) analogues of a platinum-acridine antitumor agent are only moderately cytotoxic but show potent activity against Mycobacterium tuberculosis. J Med Chem. 2009 Nov 12; 52(21):6519-22.
    View in: PubMed
    Score: 0.005
  21. Kheradi AR, Saluta G, Kucera GL, Day CS, Bierbach U. Synthesis and biological evaluation of platinum-acridine hybrid agents modified with bipyridine non-leaving groups. Bioorg Med Chem Lett. 2009 Jul 01; 19(13):3423-5.
    View in: PubMed
    Score: 0.005
  22. Ma Z, Choudhury JR, Wright MW, Day CS, Saluta G, Kucera GL, Bierbach U. A non-cross-linking platinum-acridine agent with potent activity in non-small-cell lung cancer. J Med Chem. 2008 Dec 11; 51(23):7574-80.
    View in: PubMed
    Score: 0.004
  23. Ma Z, Saluta G, Kucera GL, Bierbach U. Effect of linkage geometry on biological activity in thiourea- and guanidine-substituted acridines and platinum-acridines. Bioorg Med Chem Lett. 2008 Jul 01; 18(13):3799-801.
    View in: PubMed
    Score: 0.004
  24. Choudhury JR, Guddneppanavar R, Saluta G, Kucera GL, Bierbach U. Tuning the DNA conformational perturbations induced by cytotoxic platinum-acridine bisintercalators: effect of metal cis/trans isomerism and DNA threading groups. J Med Chem. 2008 Jun 12; 51(11):3069-72.
    View in: PubMed
    Score: 0.004
  25. Lentz SS, Miller BE, Kucera GL, Levine EA. Intraperitoneal hyperthermic chemotherapy using carboplatin: a phase I analysis in ovarian carcinoma. Gynecol Oncol. 2007 Jul; 106(1):207-10.
    View in: PubMed
    Score: 0.004
  26. Guddneppanavar R, Choudhury JR, Kheradi AR, Steen BD, Saluta G, Kucera GL, Day CS, Bierbach U. Effect of the diamine nonleaving group in platinum-acridinylthiourea conjugates on DNA damage and cytotoxicity. J Med Chem. 2007 May 03; 50(9):2259-63.
    View in: PubMed
    Score: 0.004
  27. Tomlinson JT, Park G, Misenheimer JA, Kucera GL, Hesp K, Manderville RA. Photoinduced cytotoxicity and thioadduct formation by a prodigiosin analogue. Org Lett. 2006 Oct 12; 8(21):4951-4.
    View in: PubMed
    Score: 0.004
  28. Guddneppanavar R, Saluta G, Kucera GL, Bierbach U. Synthesis, biological activity, and DNA-damage profile of platinum-threading intercalator conjugates designed to target adenine. J Med Chem. 2006 Jun 01; 49(11):3204-14.
    View in: PubMed
    Score: 0.004
  29. Xu M, Floyd HS, Greth SM, Chang WC, Lohman K, Stoyanova R, Kucera GL, Kute TE, Willingham MC, Miller MS. Perillyl alcohol-mediated inhibition of lung cancer cell line proliferation: potential mechanisms for its chemotherapeutic effects. Toxicol Appl Pharmacol. 2004 Mar 01; 195(2):232-46.
    View in: PubMed
    Score: 0.003
  30. Barry CG, Turney EC, Day CS, Saluta G, Kucera GL, Bierbach U. Thermally inert metal ammines as light-inducible DNA-targeted agents. Synthesis, photochemistry, and photobiology of a prototypical rhodium(III)-intercalator conjugate. Inorg Chem. 2002 Dec 30; 41(26):7159-69.
    View in: PubMed
    Score: 0.003
  31. Melvin MS, Tomlinson JT, Park G, Day CS, Saluta GR, Kucera GL, Manderville RA. Influence of the a-ring on the proton affinity and anticancer properties of the prodigiosins. Chem Res Toxicol. 2002 May; 15(5):734-41.
    View in: PubMed
    Score: 0.003
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.