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Eric S. Kirkendall MD, MBI

TitleProfessor
InstitutionWake Forest School of Medicine
DepartmentPediatrics, Hospitalists
Address
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    Other Positions
    TitleProfessor
    InstitutionWake Forest School of Medicine
    DepartmentImplementation Science (Public Health Sciences)

    TitleCo-Director
    InstitutionWake Forest School of Medicine
    DepartmentCenter for Healthcare Innovations (CHI)


    Collapse Research 
    Collapse research activities and funding
    R01LM012230     (MELTON, KRISTIN R)Sep 15, 2015 - Aug 31, 2020
    NIH
    Improving Intensive Care Medication Safety through EHR-basedAlgorithms.
    Role: Co-Principal Investigator
    R18HS026644     (WALSH, KATHLEEN ELIZABETH)Sep 30, 2018 - Sep 29, 2022
    NIH
    Ambulatory Pediatric Safety Learning Lab
    Role: Co-Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Orenstein EW, Kandaswamy S, Muthu N, Chaparro JD, Hagedorn PA, Dziorny AC, Moses A, Hernandez S, Khan A, Huth HB, Beus JM, Kirkendall ES. Alert burden in pediatric hospitals: a cross-sectional analysis of six academic pediatric health systems using novel metrics. J Am Med Inform Assoc. 2021 Nov 25; 28(12):2654-2660. PMID: 34664664.
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    2. Frintner MP, Kaelber DC, Kirkendall ES, Lourie EM, Somberg CA, Lehmann CU. The Effect of Electronic Health Record Burden on Pediatricians' Work-Life Balance and Career Satisfaction. Appl Clin Inform. 2021 05; 12(3):697-707. PMID: 34341980.
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    3. Kirkendall E, Huth H, Rauenbuehler B, Moses A, Melton K, Ni Y. The Generalizability of a Medication Administration Discrepancy Detection System: Quantitative Comparative Analysis. JMIR Med Inform. 2020 Dec 02; 8(12):e22031. PMID: 33263548.
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    4. Kirkendall ES, Timmons K, Huth H, Walsh K, Melton K. Human-Based Errors Involving Smart Infusion Pumps: A Catalog of Error Types and Prevention Strategies. Drug Saf. 2020 11; 43(11):1073-1087. PMID: 32797355.
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    5. Ni Y, Lingren T, Huth H, Timmons K, Melton K, Kirkendall E. Integrating and Evaluating the Data Quality and Utility of Smart Pump Information in Detecting Medication Administration Errors: Evaluation Study. JMIR Med Inform. 2020 Sep 02; 8(9):e19774. PMID: 32876578.
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    6. O'Donnell H.C., Suresh S., Webber E.C., Alexander G.M., Chung S.L., Hamling A.M., Kirkendall E.S., Mann A.M., O'Donnell H.C., Sadeghian R., Shelov E., Suresh S., Wiesenthal A.M. Pediatrics. Electronic documentation in pediatrics: The rationale and functionality requirements. 2020; 146(1). View Publication.
    7. van Camp PJ, Kirkendall ES, Hagedorn PA, Minich T, Kouril M, Spooner SA, Gecili E, Dexheimer JW. Feedback at the Point of Care to Decrease Medication Alert Rates in an Electronic Health Record. Pediatr Emerg Care. 2020 Jul; 36(7):e417-e422. PMID: 31136457.
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    8. Dewan M, Muthu N, Shelov E, Bonafide CP, Brady P, Davis D, Kirkendall ES, Niles D, Sutton RM, Traynor D, Tegtmeyer K, Nadkarni V, Wolfe H. Performance of a Clinical Decision Support Tool to Identify PICU Patients at High Risk for Clinical Deterioration. Pediatr Crit Care Med. 2020 02; 21(2):129-135. PMID: 31577691.
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    9. Vinks AA, Punt NC, Menke F, Kirkendall E, Butler D, Duggan TJ, Cortezzo DE, Kiger S, Dietrich T, Spencer P, Keefer R, Setchell KDR, Zhao J, Euteneuer JC, Mizuno T, Dufendach KR. Electronic Health Record-Embedded Decision Support Platform for Morphine Precision Dosing in Neonates. Clin Pharmacol Ther. 2020 01; 107(1):186-194. PMID: 31618453.
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    10. Melton KR, Timmons K, Walsh KE, Meinzen-Derr JK, Kirkendall E. Smart pumps improve medication safety but increase alert burden in neonatal care. BMC Med Inform Decis Mak. 2019 11 07; 19(1):213. PMID: 31699078.
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    11. Goldstein SL, Dahale D, Kirkendall ES, Mottes T, Kaplan H, Muething S, Askenazi DJ, Henderson T, Dill L, Somers MJG, Kerr J, Gilarde J, Zaritsky J, Bica V, Brophy PD, Misurac J, Hackbarth R, Steinke J, Mooney J, Ogrin S, Chadha V, Warady B, Ogden R, Hoebing W, Symons J, Yonekawa K, Menon S, Abrams L, Sutherland S, Weng P, Zhang F, Walsh K. A prospective multi-center quality improvement initiative (NINJA) indicates a reduction in nephrotoxic acute kidney injury in hospitalized children. Kidney Int. 2020 03; 97(3):580-588. PMID: 31980139.
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    12. Lehmann C.U., Kirkendall E.S., Temple M.W., Sisk B., Krams L., Schneider J.H. Pediatrics. Council on Clinical Information Technology. Meeting Abstract. Use of electronic health records in pediatric office settings. 2019; 144:27. View Publication.
    13. Hagedorn PA, Kirkendall ES, Spooner SA, Mohan V. Inpatient Communication Networks: Leveraging Secure Text-Messaging Platforms to Gain Insight into Inpatient Communication Systems. Appl Clin Inform. 2019 05; 10(3):471-478. PMID: 31242514.
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    14. Grabel MZ, Vaughan BL, Dexheimer JW, Kirkendall ES. Mathematical Model for Computer-Assisted Modification of Medication Dosing Rules. Biomed Inform Insights. 2019; 11:1178222619829079. PMID: 31190853.
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    15. Kirkendall ES, Ni Y, Lingren T, Leonard M, Hall ES, Melton K. Data Challenges With Real-Time Safety Event Detection And Clinical Decision Support. J Med Internet Res. 2019 05 22; 21(5):e13047. PMID: 31120022.
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    16. Temple MW, Sisk B, Krams LA, Schneider JH, Kirkendall ES, Lehmann CU. Trends in Use of Electronic Health Records in Pediatric Office Settings. J Pediatr. 2019 03; 206:164-171.e2. PMID: 30527749.
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    17. Wu DTY, Meganathan K, Newcomb M, Ni Y, Dexheimer JW, Kirkendall ES, Spooner SA. A Comparison of Existing Methods to Detect Weight Data Errors in a Pediatric Academic Medical Center. AMIA Annu Symp Proc. 2018; 2018:1103-1109. PMID: 30815152.
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    18. Halvorson EE, Thurtle DP, Kirkendall ES. Identifying Pediatric Patients at High Risk for Adverse Events in the Hospital. Hosp Pediatr. 2019 01; 9(1):67-69. PMID: 30509901.
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    19. Ni Y, Lingren T, Hall ES, Leonard M, Melton K, Kirkendall ES. Designing and evaluating an automated system for real-time medication administration error detection in a neonatal intensive care unit. J Am Med Inform Assoc. 2018 05 01; 25(5):555-563. PMID: 29329456.
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    20. Wellner B, Grand J, Canzone E, Coarr M, Brady PW, Simmons J, Kirkendall E, Dean N, Kleinman M, Sylvester P. Predicting Unplanned Transfers to the Intensive Care Unit: A Machine Learning Approach Leveraging Diverse Clinical Elements. JMIR Med Inform. 2017 Nov 22; 5(4):e45. PMID: 29167089.
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    21. Guiot AB, Kirkendall ES, Gosdin CH, Shah SS, DeBlasio DJ, Meier KA, O'Toole JK. Educational Added Value Unit: Development and Testing of a Measure for Educational Activities. Hosp Pediatr. 2017 Nov; 7(11):675-681. PMID: 29018043.
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    22. Tang H, Solti I, Kirkendall E, Zhai H, Lingren T, Meller J, Ni Y. Leveraging Food and Drug Administration Adverse Event Reports for the Automated Monitoring of Electronic Health Records in a Pediatric Hospital. Biomed Inform Insights. 2017; 9:1178222617713018. PMID: 28634427.
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    23. Dexheimer JW, Kirkendall ES, Kouril M, Hagedorn PA, Minich T, Duan LL, Mahdi M, Szczesniak R, Spooner SA. The Effects of Medication Alerts on Prescriber Response in a Pediatric Hospital. Appl Clin Inform. 2017 05 10; 8(2):491-501. PMID: 28487930.
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    24. Hagedorn PA, Kirkendall ES, Kouril M, Dexheimer JW, Courter J, Minich T, Spooner SA. Assessing Frequency and Risk of Weight Entry Errors in Pediatrics. JAMA Pediatr. 2017 04 01; 171(4):392-393. PMID: 28152133.
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    25. Kirkendall ES, Kouril M, Dexheimer JW, Courter JD, Hagedorn P, Szczesniak R, Li D, Damania R, Minich T, Spooner SA. Automated identification of antibiotic overdoses and adverse drug events via analysis of prescribing alerts and medication administration records. J Am Med Inform Assoc. 2017 Mar 01; 24(2):295-302. PMID: 27507653.
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    26. Kirkendall ES. Casting a Wider Safety Net: The Promise of Electronic Safety Event Detection Systems. Jt Comm J Qual Patient Saf. 2017 04; 43(4):153-154. PMID: 28325202.
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    27. Gipson DS, Kirkendall ES, Gumbs-Petty B, Quinn T, Steen A, Hicks A, McMahon A, Nicholas S, Zhao-Wong A, Taylor-Zapata P, Turner M, Herreshoff E, Jones C, Davis JM, Haber M, Hirschfeld S. Development of a Pediatric Adverse Events Terminology. Pediatrics. 2017 01; 139(1). PMID: 28028203.
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    28. Stockwell DC, Bisarya H, Classen DC, Kirkendall ES, Lachman PI, Matlow AG, Tham E, Hyman D, Lehman SM, Searles E, Muething SE, Sharek PJ. Development of an Electronic Pediatric All-Cause Harm Measurement Tool Using a Modified Delphi Method. J Patient Saf. 2016 12; 12(4):180-189. PMID: 25162206.
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    29. Borycki E, Dexheimer JW, Hullin Lucay Cossio C, Gong Y, Jensen S, Kaipio J, Kennebeck S, Kirkendall E, Kushniruk AW, Kuziemsky C, Marcilly R, Röhrig R, Saranto K, Senathirajah Y, Weber J, Takeda H. Methods for Addressing Technology-induced Errors: The Current State. Yearb Med Inform. 2016 Nov 10; (1):30-40. PMID: 27830228.
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    30. Proceedings of the 8th Annual Conference on the Science of Dissemination and Implementation : Washington, DC, USA. 14-15 December 2015. Implement Sci. 2016 Aug 01; 11 Suppl 2:100. PMID: 27490260.
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    31. Goldstein SL, Mottes T, Simpson K, Barclay C, Muething S, Haslam DB, Kirkendall ES. A sustained quality improvement program reduces nephrotoxic medication-associated acute kidney injury. Kidney Int. 2016 07; 90(1):212-21. PMID: 27217196.
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    32. Hagedorn PA, Shah SS, Kirkendall ES. Following the (Clinical Decision) Rules: Opportunities for Improving Safety and Resource Utilization With the Bacterial Meningitis Score. Hosp Pediatr. 2016 May; 6(5):305-9. PMID: 27056987.
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    33. Li Q, Kirkendall ES, Hall ES, Ni Y, Lingren T, Kaiser M, Lingren N, Zhai H, Solti I, Melton K. Automated detection of medication administration errors in neonatal intensive care. J Biomed Inform. 2015 Oct; 57:124-33. PMID: 26190267.
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    34. Stockwell DC, Bisarya H, Classen DC, Kirkendall ES, Landrigan CP, Lemon V, Tham E, Hyman D, Lehman SM, Searles E, Hall M, Muething SE, Schuster MA, Sharek PJ. A trigger tool to detect harm in pediatric inpatient settings. Pediatrics. 2015 Jun; 135(6):1036-42. PMID: 25986015.
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    35. Menon S, Kirkendall ES, Nguyen H, Goldstein SL. Acute kidney injury associated with high nephrotoxic medication exposure leads to chronic kidney disease after 6 months. J Pediatr. 2014 Sep; 165(3):522-7.e2. PMID: 24928698.
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    36. Kirkendall ES, Spires WL, Mottes TA, Schaffzin JK, Barclay C, Goldstein SL. Development and performance of electronic acute kidney injury triggers to identify pediatric patients at risk for nephrotoxic medication-associated harm. Appl Clin Inform. 2014; 5(2):313-33. PMID: 25024752.
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    37. Li Q, Melton K, Lingren T, Kirkendall ES, Hall E, Zhai H, Ni Y, Kaiser M, Stoutenborough L, Solti I. Phenotyping for patient safety: algorithm development for electronic health record based automated adverse event and medical error detection in neonatal intensive care. J Am Med Inform Assoc. 2014 Sep-Oct; 21(5):776-84. PMID: 24401171.
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    38. Kirkendall ES, Kouril M, Minich T, Spooner SA. Analysis of electronic medication orders with large overdoses: opportunities for mitigating dosing errors. Appl Clin Inform. 2014; 5(1):25-45. PMID: 24734122.
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    39. Brady PW, Brinkman WB, Simmons JM, Yau C, White CM, Kirkendall ES, Schaffzin JK, Conway PH, Vossmeyer MT. Oral antibiotics at discharge for children with acute osteomyelitis: a rapid cycle improvement project. BMJ Qual Saf. 2014 Jun; 23(6):499-507. PMID: 24347649.
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    40. Stockwell DC, Kirkendall E, Muething SE, Kloppenborg E, Vinodrao H, Jacobs BR. Automated adverse event detection collaborative: electronic adverse event identification, classification, and corrective actions across academic pediatric institutions. J Patient Saf. 2013 Dec; 9(4):203-10. PMID: 24257063.
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    41. Deleger L, Brodzinski H, Zhai H, Li Q, Lingren T, Kirkendall ES, Alessandrini E, Solti I. Developing and evaluating an automated appendicitis risk stratification algorithm for pediatric patients in the emergency department. J Am Med Inform Assoc. 2013 Dec; 20(e2):e212-20. PMID: 24130231.
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    42. Kirkendall ES, Goldenhar LM, Simon JL, Wheeler DS, Andrew Spooner S. Transitioning from a computerized provider order entry and paper documentation system to an electronic health record: expectations and experiences of hospital staff. Int J Med Inform. 2013 Nov; 82(11):1037-45. PMID: 24041453.
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    43. Goldstein SL, Kirkendall E, Nguyen H, Schaffzin JK, Bucuvalas J, Bracke T, Seid M, Ashby M, Foertmeyer N, Brunner L, Lesko A, Barclay C, Lannon C, Muething S. Electronic health record identification of nephrotoxin exposure and associated acute kidney injury. Pediatrics. 2013 Sep; 132(3):e756-67. PMID: 23940245.
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    44. Kirkendall ES, Spooner SA, Logan JR. Evaluating the accuracy of electronic pediatric drug dosing rules. J Am Med Inform Assoc. 2014 Feb; 21(e1):e43-9. PMID: 23813541.
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    45. Gouripeddi R, Warner PB, Mo P, Levin JE, Srivastava R, Shah SS, de Regt D, Kirkendall E, Bickel J, Korgenski EK, Precourt M, Stepanek RL, Mitchell JA, Narus SP, Keren R. Federating clinical data from six pediatric hospitals: process and initial results for microbiology from the PHIS+ consortium. AMIA Annu Symp Proc. 2012; 2012:281-90. PMID: 23304298.
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    46. Kirkendall ES, Kloppenborg E, Papp J, White D, Frese C, Hacker D, Schoettker PJ, Muething S, Kotagal U. Measuring adverse events and levels of harm in pediatric inpatients with the Global Trigger Tool. Pediatrics. 2012 Nov; 130(5):e1206-14. PMID: 23045558.
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    47. Kirkendall ES, Guiot AB. Torsed pulmonary sequestration presenting with gastrointestinal manifestations. Clin Pediatr (Phila). 2013 Oct; 52(10):981-4. PMID: 22890328.
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    48. Narus SP, Srivastava R, Gouripeddi R, Livne OE, Mo P, Bickel JP, de Regt D, Hales JW, Kirkendall E, Stepanek RL, Toth J, Keren R. Federating clinical data from six pediatric hospitals: process and initial results from the PHIS+ Consortium. AMIA Annu Symp Proc. 2011; 2011:994-1003. PMID: 22195159.
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