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Connection

Donald Mcclain to Humans

This is a "connection" page, showing publications Donald Mcclain has written about Humans.
Connection Strength

0.628
  1. Salaye L, Bychkova I, Sink S, Kovalic AJ, Bharadwaj MS, Lorenzo F, Jain S, Harrison AV, Davis AT, Turnbull K, Meegalla NT, Lee SH, Cooksey R, Donati GL, Kavanagh K, Bonkovsky HL, McClain DA. A Low Iron Diet Protects from Steatohepatitis in a Mouse Model. Nutrients. 2019 Sep 10; 11(9).
    View in: PubMed
    Score: 0.037
  2. McClain DA, Sharma NK, Jain S, Harrison A, Salaye LN, Comeau ME, Langefeld CD, Lorenzo FR, Das SK. Adipose Tissue Transferrin and Insulin Resistance. J Clin Endocrinol Metab. 2018 11 01; 103(11):4197-4208.
    View in: PubMed
    Score: 0.035
  3. Ge RL, Simonson TS, Gordeuk V, Prchal JT, McClain DA. Metabolic aspects of high-altitude adaptation in Tibetans. Exp Physiol. 2015 Nov; 100(11):1247-55.
    View in: PubMed
    Score: 0.028
  4. Simcox JA, Mitchell TC, Gao Y, Just SF, Cooksey R, Cox J, Ajioka R, Jones D, Lee SH, King D, Huang J, McClain DA. Dietary iron controls circadian hepatic glucose metabolism through heme synthesis. Diabetes. 2015 Apr; 64(4):1108-19.
    View in: PubMed
    Score: 0.026
  5. Abbas MA, Abraham D, Kushner JP, McClain DA. Anti-obesity and pro-diabetic effects of hemochromatosis. Obesity (Silver Spring). 2014 Oct; 22(10):2120-2.
    View in: PubMed
    Score: 0.026
  6. Creighton Mitchell T, McClain DA. Diabetes and hemochromatosis. Curr Diab Rep. 2014; 14(5):488.
    View in: PubMed
    Score: 0.025
  7. Simcox JA, McClain DA. Iron and diabetes risk. Cell Metab. 2013 Mar 05; 17(3):329-41.
    View in: PubMed
    Score: 0.024
  8. Byington CL, Savitz L, Varner M, McClain D. The Utah Center for Clinical and Translational Science: transformation through collaboration. Clin Transl Sci. 2012 Oct; 5(5):377-8.
    View in: PubMed
    Score: 0.023
  9. McClain DA, Abuelgasim KA, Nouraie M, Salomon-Andonie J, Niu X, Miasnikova G, Polyakova LA, Sergueeva A, Okhotin DJ, Cherqaoui R, Okhotin D, Cox JE, Swierczek S, Song J, Simon MC, Huang J, Simcox JA, Yoon D, Prchal JT, Gordeuk VR. Decreased serum glucose and glycosylated hemoglobin levels in patients with Chuvash polycythemia: a role for HIF in glucose metabolism. J Mol Med (Berl). 2013 Jan; 91(1):59-67.
    View in: PubMed
    Score: 0.023
  10. Gabrielsen JS, Gao Y, Simcox JA, Huang J, Thorup D, Jones D, Cooksey RC, Gabrielsen D, Adams TD, Hunt SC, Hopkins PN, Cefalu WT, McClain DA. Adipocyte iron regulates adiponectin and insulin sensitivity. J Clin Invest. 2012 Oct; 122(10):3529-40.
    View in: PubMed
    Score: 0.023
  11. Ge RL, Simonson TS, Cooksey RC, Tanna U, Qin G, Huff CD, Witherspoon DJ, Xing J, Zhengzhong B, Prchal JT, Jorde LB, McClain DA. Metabolic insight into mechanisms of high-altitude adaptation in Tibetans. Mol Genet Metab. 2012 Jun; 106(2):244-7.
    View in: PubMed
    Score: 0.022
  12. Soesanto Y, Luo B, Parker G, Jones D, Cooksey RC, McClain DA. Pleiotropic and age-dependent effects of decreased protein modification by O-linked N-acetylglucosamine on pancreatic ß-cell function and vascularization. J Biol Chem. 2011 Jul 22; 286(29):26118-26.
    View in: PubMed
    Score: 0.021
  13. Huang J, Jones D, Luo B, Sanderson M, Soto J, Abel ED, Cooksey RC, McClain DA. Iron overload and diabetes risk: a shift from glucose to Fatty Acid oxidation and increased hepatic glucose production in a mouse model of hereditary hemochromatosis. Diabetes. 2011 Jan; 60(1):80-7.
    View in: PubMed
    Score: 0.020
  14. Cooksey RC, McClain DA. Increased hexosamine pathway flux and high fat feeding are not additive in inducing insulin resistance: evidence for a shared pathway. Amino Acids. 2011 Mar; 40(3):841-6.
    View in: PubMed
    Score: 0.020
  15. McClain DA. Bridging the gap between basic and clinical investigation. Trends Biochem Sci. 2010 Apr; 35(4):187-8.
    View in: PubMed
    Score: 0.019
  16. Marcus RL, Lastayo PC, Dibble LE, Hill L, McClain DA. Increased strength and physical performance with eccentric training in women with impaired glucose tolerance: a pilot study. J Womens Health (Larchmt). 2009 Feb; 18(2):253-60.
    View in: PubMed
    Score: 0.018
  17. Taylor RP, Geisler TS, Chambers JH, McClain DA. Up-regulation of O-GlcNAc transferase with glucose deprivation in HepG2 cells is mediated by decreased hexosamine pathway flux. J Biol Chem. 2009 Feb 06; 284(6):3425-32.
    View in: PubMed
    Score: 0.018
  18. McClain DA. Introduction to a mini-forum on "glyconutrients". Glycobiology. 2008 Sep; 18(9):651.
    View in: PubMed
    Score: 0.017
  19. Jouihan HA, Cobine PA, Cooksey RC, Hoagland EA, Boudina S, Abel ED, Winge DR, McClain DA. Iron-mediated inhibition of mitochondrial manganese uptake mediates mitochondrial dysfunction in a mouse model of hemochromatosis. Mol Med. 2008 Mar-Apr; 14(3-4):98-108.
    View in: PubMed
    Score: 0.017
  20. Taylor RP, Parker GJ, Hazel MW, Soesanto Y, Fuller W, Yazzie MJ, McClain DA. Glucose deprivation stimulates O-GlcNAc modification of proteins through up-regulation of O-linked N-acetylglucosaminyltransferase. J Biol Chem. 2008 Mar 07; 283(10):6050-7.
    View in: PubMed
    Score: 0.016
  21. Luo B, Soesanto Y, McClain DA. Protein modification by O-linked GlcNAc reduces angiogenesis by inhibiting Akt activity in endothelial cells. Arterioscler Thromb Vasc Biol. 2008 Apr; 28(4):651-7.
    View in: PubMed
    Score: 0.016
  22. Abraham D, Sharma PK, Bentz J, Gault PM, Neumayer L, McClain DA. Utility of ultrasound-guided fine-needle aspiration of parathyroid adenomas for localization before minimally invasive parathyroidectomy. Endocr Pract. 2007 Jul-Aug; 13(4):333-7.
    View in: PubMed
    Score: 0.016
  23. Hazel M, Cooksey RC, Jones D, Parker G, Neidigh JL, Witherbee B, Gulve EA, McClain DA. Activation of the hexosamine signaling pathway in adipose tissue results in decreased serum adiponectin and skeletal muscle insulin resistance. Endocrinology. 2004 May; 145(5):2118-28.
    View in: PubMed
    Score: 0.012
  24. McClain DA, Lubas WA, Cooksey RC, Hazel M, Parker GJ, Love DC, Hanover JA. Altered glycan-dependent signaling induces insulin resistance and hyperleptinemia. Proc Natl Acad Sci U S A. 2002 Aug 06; 99(16):10695-9.
    View in: PubMed
    Score: 0.011
  25. McClain DA. Hexosamines as mediators of nutrient sensing and regulation in diabetes. J Diabetes Complications. 2002 Jan-Feb; 16(1):72-80.
    View in: PubMed
    Score: 0.011
  26. Shah BN, Hassan TO, Zhang X, McClain DA, Gordeuk VR. Increased iron stores influence glucose metabolism in sickle cell anaemia. Br J Haematol. 2020 05; 189(4):e184-e187.
    View in: PubMed
    Score: 0.010
  27. Daniels MC, McClain DA, Crook ED. Transcriptional Regulation of Transforming Growth Factor ß1 by Glucose: Investigation into the Role of the Hexosamine Biosynthesis Pathway. Am J Med Sci. 2020 02; 359(2):79-83.
    View in: PubMed
    Score: 0.009
  28. Shannon C, Merovci A, Xiong J, Tripathy D, Lorenzo F, McClain D, Abdul-Ghani M, Norton L, DeFronzo RA. Effect of Chronic Hyperglycemia on Glucose Metabolism in Subjects With Normal Glucose Tolerance. Diabetes. 2018 12; 67(12):2507-2517.
    View in: PubMed
    Score: 0.009
  29. Lamar ZS, Dothard A, Kennedy L, Isom S, Robinson M, Vaidya R, Hurd D, McClain D, Lesser G. Hyperglycemia during first-line R-CHOP or dose adjusted R-EPOCH chemotherapy for non-Hodgkin lymphoma is prevalent and associated with chemotherapy alteration - a retrospective study. Leuk Lymphoma. 2018 08; 59(8):1871-1877.
    View in: PubMed
    Score: 0.008
  30. Fernández-Real JM, McClain D, Manco M. Mechanisms Linking Glucose Homeostasis and Iron Metabolism Toward the Onset and Progression of Type 2 Diabetes. Diabetes Care. 2015 Nov; 38(11):2169-76.
    View in: PubMed
    Score: 0.007
  31. Zhang X, Zhang W, Saraf SL, Nouraie M, Han J, Gowhari M, Hassan J, Miasnikova G, Sergueeva A, Nekhai S, Kittles R, Machado RF, Garcia JG, Gladwin MT, Steinberg MH, Sebastiani P, McClain DA, Gordeuk VR. Genetic polymorphism of APOB is associated with diabetes mellitus in sickle cell disease. Hum Genet. 2015 Aug; 134(8):895-904.
    View in: PubMed
    Score: 0.007
  32. Kwon OS, Tanner RE, Barrows KM, Runtsch M, Symons JD, Jalili T, Bikman BT, McClain DA, O'Connell RM, Drummond MJ. MyD88 regulates physical inactivity-induced skeletal muscle inflammation, ceramide biosynthesis signaling, and glucose intolerance. Am J Physiol Endocrinol Metab. 2015 Jul 01; 309(1):E11-21.
    View in: PubMed
    Score: 0.007
  33. Lorenzo FR, Huff C, Myllymäki M, Olenchock B, Swierczek S, Tashi T, Gordeuk V, Wuren T, Ri-Li G, McClain DA, Khan TM, Koul PA, Guchhait P, Salama ME, Xing J, Semenza GL, Liberzon E, Wilson A, Simonson TS, Jorde LB, Kaelin WG, Koivunen P, Prchal JT. A genetic mechanism for Tibetan high-altitude adaptation. Nat Genet. 2014 Sep; 46(9):951-6.
    View in: PubMed
    Score: 0.007
  34. Carlin MB, Tanner RE, Agergaard J, Jalili T, McClain DA, Drummond MJ. Skeletal muscle Ras-related GTP binding B mRNA and protein expression is increased after essential amino acid ingestion in healthy humans. J Nutr. 2014 Sep; 144(9):1409-14.
    View in: PubMed
    Score: 0.006
  35. Drummond MJ, Addison O, Brunker L, Hopkins PN, McClain DA, LaStayo PC, Marcus RL. Downregulation of E3 ubiquitin ligases and mitophagy-related genes in skeletal muscle of physically inactive, frail older women: a cross-sectional comparison. J Gerontol A Biol Sci Med Sci. 2014 Aug; 69(8):1040-8.
    View in: PubMed
    Score: 0.006
  36. Underwood PC, Chamarthi B, Williams JS, Vaidya A, Garg R, Adler GK, Grotzke MP, Staskus G, Wadwekar D, Hopkins PN, Ferri C, McCall A, McClain D, Williams GH. Nonmodulation as the mechanism for salt sensitivity of blood pressure in individuals with hypertension and type 2 diabetes mellitus. J Clin Endocrinol Metab. 2012 Oct; 97(10):3775-82.
    View in: PubMed
    Score: 0.006
  37. Shamoon H, Center D, Davis P, Tuchman M, Ginsberg H, Califf R, Stephens D, Mellman T, Verbalis J, Nadler L, Shekhar A, Ford D, Rizza R, Shaker R, Brady K, Murphy B, Cronstein B, Hochman J, Greenland P, Orwoll E, Sinoway L, Greenberg H, Jackson R, Coller B, Topol E, Guay-Woodford L, Runge M, Clark R, McClain D, Selker H, Lowery C, Dubinett S, Berglund L, Cooper D, Firestein G, Johnston SC, Solway J, Heubi J, Sokol R, Nelson D, Tobacman L, Rosenthal G, Aaronson L, Barohn R, Kern P, Sullivan J, Shanley T, Blazar B, Larson R, FitzGerald G, Reis S, Pearson T, Buchanan T, McPherson D, Brasier A, Toto R, Disis M, Drezner M, Bernard G, Clore J, Evanoff B, Imperato-McGinley J, Sherwin R, Pulley J. Preparedness of the CTSA's structural and scientific assets to support the mission of the National Center for Advancing Translational Sciences (NCATS). Clin Transl Sci. 2012 Apr; 5(2):121-9.
    View in: PubMed
    Score: 0.006
  38. Simonson TS, McClain DA, Jorde LB, Prchal JT. Genetic determinants of Tibetan high-altitude adaptation. Hum Genet. 2012 Apr; 131(4):527-33.
    View in: PubMed
    Score: 0.005
  39. Flann KL, LaStayo PC, McClain DA, Hazel M, Lindstedt SL. Muscle damage and muscle remodeling: no pain, no gain? J Exp Biol. 2011 Feb 15; 214(Pt 4):674-9.
    View in: PubMed
    Score: 0.005
  40. Shakya A, Cooksey R, Cox JE, Wang V, McClain DA, Tantin D. Oct1 loss of function induces a coordinate metabolic shift that opposes tumorigenicity. Nat Cell Biol. 2009 Mar; 11(3):320-7.
    View in: PubMed
    Score: 0.004
  41. Hsueh W, Abel ED, Breslow JL, Maeda N, Davis RC, Fisher EA, Dansky H, McClain DA, McIndoe R, Wassef MK, Rabadán-Diehl C, Goldberg IJ. Recipes for creating animal models of diabetic cardiovascular disease. Circ Res. 2007 May 25; 100(10):1415-27.
    View in: PubMed
    Score: 0.004
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.