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Bonnie C. Sachs PhD, ABPP

TitleAssociate Professor
InstitutionWake Forest School of Medicine
DepartmentNeurology, Neuropsychology
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    Other Positions
    TitleProfessor
    InstitutionWake Forest School of Medicine
    DepartmentInternal Medicine, Gerontology & Geriatric Medicine

    TitleProfessor
    InstitutionWake Forest School of Medicine
    DepartmentSocial Sciences & Health Policy (Public Health Sciences)

    TitleAssociate Professor
    InstitutionWake Forest School of Medicine
    DepartmentInternal Medicine, Gerontology & Geriatric Medicine


    Collapse Biography 
    Collapse education and training
    Virginia Tech, Blacksburg, VAB.S.05/2000Psychology
    University of Florida, Gainesville, FLM.S.05/2005Clinical Neuropsychology
    University of Florida, Gainesville, FLPh.D.07/2009Clinical Neuropsychology
    Emory University, Atlanta, GA07/2009Neuropsychology Internship
    Mayo Clinic, Jacksonville, FL07/2011Neuropsychology Fellowship

    Collapse Overview 
    Collapse overview
    Dr. Bonnie Sachs is a board-certified clinical neuropsychologist who specializes in working with older adults with memory loss and other cognitive disorders. Her areas of focus, both clinically and in research, include mild cognitive impairment (MCI), Alzheimer's disease (AD), and other forms of neurodegenerative diseases like Parkinson's disease, Frontotemporal dementia, Vascular dementia, and Lewy Body dementia. Dr. Sachs is an Associate Professor in the Departments of Neurology and Internal Medicine, Section of Gerontology & Geriatric Medicine, and is also an Investigator with the Wake Forest Alzheimer's Disease Research Center (ADRC). Additionally, Dr. Sachs enjoys education training and she currently co-directs the Clinical Neuropsychology Fellowship Program at the Wake Forest School of Medicine.

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Sachs BC, Latham LA, Bateman JR, Cleveland MJ, Espeland MA, Fischer E, Gaussoin SA, Leng I, Rapp SR, Rogers S, Shappell HM, Williams BJ, Yang M, Craft S. Feasibility of Remote Administration of the Uniform Data Set-Version 3 for Assessment of Older Adults With Mild Cognitive Impairment and Alzheimer's Disease. Arch Clin Neuropsychol. 2024 Jul 24; 39(5):635-643. PMID: 38291734.
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    2. Duran T, Gaussoin SA, Latham LA, Rundle MM, Espeland MA, Williams BJ, Hughes TM, Craft S, Sachs BC, Bateman JR, Lockhart SN. Examining a Preclinical Alzheimer's Cognitive Composite for Telehealth Administration for Reliability Between In-Person and Remote Cognitive Testing with Neuroimaging Biomarkers. J Alzheimers Dis. 2024 Apr 26. PMID: 38669545.
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    3. Petkus AJ, Wang X, Younan D, Salminen LE, Resnick SM, Rapp SR, Espeland MA, Gatz M, Widaman KF, Casanova R, Chui H, Barnard RT, Gaussoin SA, Goveas JS, Hayden KM, Henderson VW, Sachs BC, Saldana S, Shadyab AH, Shumaker SA, Chen JC. 20-year depressive symptoms, dementia, and structural neuropathology in older women. Alzheimers Dement. 2024 Apr 09. PMID: 38591250.
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    4. Hayden KM, Mielke MM, Evans JK, Neiberg R, Molina-Henry D, Culkin M, Marcovina S, Johnson KC, Carmichael OT, Rapp SR, Sachs BC, Ding J, Shappell H, Wagenknecht L, Luchsinger JA, Espeland MA. Erratum to: Association between Modifiable Risk Factors and Levels of Blood-Based Biomarkers of Alzheimer's and Related Dementias in the Look AHEAD Cohort. JAR Life. 2024; 13:29. PMID: 38533271.
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    5. Hayden KM, Mielke MM, Evans JK, Neiberg R, Molina-Henry D, Culkin M, Marcovina S, Johnson KC, Carmichael OT, Rapp SR, Sachs BC, Ding J, Shappell H, Wagenknecht L, Luchsinger JA, Espeland MA. Association between Modifiable Risk Factors and Levels of Blood-Based Biomarkers of Alzheimer's and Related Dementias in the Look AHEAD Cohort. JAR Life. 2024; 13:1-21. PMID: 38204926.
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    6. Sachs BC, Williams BJ, Gaussoin SA, Baker LD, Manson JE, Espeland MA, Sesso HD, Shumaker SA, Rapp SR. Impact of multivitamin-mineral and cocoa extract on incidence of mild cognitive impairment and dementia: Results from the COcoa Supplement and Multivitamin Outcomes Study for the Mind (COSMOS-Mind). Alzheimers Dement. 2023 Nov; 19(11):4863-4871. PMID: 37035889.
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    7. Bancks MP, Byrd GS, Caban-Holt A, Fitzpatrick AL, Forrester SN, Hayden KM, Heckbert SR, Kershaw KN, Rapp SR, Sachs BC, Hughes TM. Self-reported experiences of discrimination and incident dementia. Alzheimers Dement. 2023 Jul; 19(7):3119-3128. PMID: 36724324.
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    8. Hughes TM, Lockhart SN, Suerken CK, Jung Y, Whitlow CT, Bateman JR, Williams BJ, Espeland MA, Sachs BC, Williamson J, Cleveland M, Yang M, Rogers S, Hayden KM, Baker LD, Craft S. Hypertensive Aspects of Cardiometabolic Disorders Are Associated with Lower Brain Microstructure, Perfusion, and Cognition. J Alzheimers Dis. 2022 Oct 28. PMID: 36314205.
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    9. Coffin C, Suerken CK, Bateman JR, Whitlow CT, Williams BJ, Espeland MA, Sachs BC, Cleveland M, Yang M, Rogers S, Hayden KM, Baker LD, Williamson J, Craft S, Hughes TM, Lockhart SN. Vascular and microstructural markers of cognitive pathology. Alzheimers Dement (Amst). 2022; 14(1):e12332. PMID: 35814618.
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    10. Sachs BC, Gaussoin SA, Brenes GA, Casanova R, Chlebowski RT, Chen JC, Luo J, Rapp SR, Shadyab AH, Shumaker S, Wactawski-Wende J, Wells GL, Hayden KM. The relationship between optimism, MCI, and dementia among postmenopausal women. Aging Ment Health. 2022 Jun 11; 1-9. PMID: 35694859.
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    11. Gaussoin SA, Pajewski NM, Chelune G, Cleveland ML, Crowe MG, Launer LJ, Lerner AJ, Martindale-Adams J, Nichols LO, Ogrocki PK, Sachs BC, Sink KM, Supiano MA, Wadley VG, Wilson VM, Wright CB, Williamson JD, Reboussin DM, Rapp SR. Effect of intensive blood pressure control on subtypes of mild cognitive impairment and risk of progression from SPRINT study. J Am Geriatr Soc. 2021 Nov 26. PMID: 34826341.
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    12. Casanova R, Gaussoin SA, Wallace R, Baker L, Chen JC, Manson JE, Henderson VW, Sachs BC, Justice J, Whitsel EA, Hayden KM, Rapp SR. Investigating Predictors of Preserved Cognitive Function in Older Women Using Machine Learning: Women's Health Initiative Memory Study. J Alzheimers Dis. 2021 Oct 07. PMID: 34633318.
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    13. Lockhart SN, Schaich CL, Craft S, Sachs BC, Rapp SR, Jung Y, Whitlow CT, Solingapuram Sai KK, Cleveland M, Williams BJ, Burke GL, Bertoni A, Hayden KM, Hughes TM. Associations among vascular risk factors, neuroimaging biomarkers, and cognition: Preliminary analyses from the Multi-Ethnic Study of Atherosclerosis (MESA). Alzheimers Dement. 2021 Sep 05. PMID: 34482601.
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    14. Sachs BC, Chelune GJ, Rapp SR, Couto AM, Willard JJ, Williamson JD, Sink KM, Coker LH, Gaussoin SA, Gure TR, Lerner AJ, Nichols LO, Still CH, Wadley VG, Pajewski NM. Robust demographically-adjusted normative data for the Montreal Cognitive Assessment (MoCA): Results from the systolic blood pressure intervention trial. Clin Neuropsychol. 2021 Sep 01; 1-16. PMID: 34470584.
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    15. Schaich CL, Yeboah J, Espeland MA, Baker LD, Ding J, Hayden KM, Sachs BC, Craft S, Rapp SR, Luchsinger JA, Fitzpatrick AL, Heckbert SR, Post WS, Burke GL, Allen NB, Hughes TM. Association of Vascular Risk Scores and Cognitive Performance in a Diverse Cohort: The Multi-Ethnic Study of Atherosclerosis. J Gerontol A Biol Sci Med Sci. 2021 Jul 03. PMID: 34216214.
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    16. Bailey MJ, Soliman EZ, McClure LA, Howard G, Howard VJ, Judd SE, Unverzagt FW, Wadley V, Sachs BC, Hughes TM. Relation of Atrial Fibrillation to Cognitive Decline (from the REasons for Geographic and Racial Differences in Stroke [REGARDS] Study). Am J Cardiol. 2021 Jun 01; 148:60-68. PMID: 33684372.
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    17. Dodge HH, Goldstein FC, Wakim NI, Gefen T, Teylan M, Chan KCG, Kukull WA, Barnes LL, Giordani B, Hughes TM, Kramer JH, Loewenstein DA, Marson DC, Mungas DM, Mattek N, Sachs BC, Salmon DP, Willis-Parker M, Welsh-Bohmer KA, Wild KV, Morris JC, Weintraub S. Differentiating among stages of cognitive impairment in aging: Version 3 of the Uniform Data Set (UDS) neuropsychological test battery and MoCA index scores. Alzheimers Dement (N Y). 2020; 6(1):e12103. PMID: 33283037.
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    18. Younan D, Wang X, Casanova R, Barnard R, Gaussoin SA, Saldana S, Petkus AJ, Beavers DP, Resnick SM, Manson JE, Serre ML, Vizuete W, Henderson VW, Sachs BC, Salinas JA, Gatz M, Espeland MA, Chui HC, Shumaker SA, Rapp SR, Chen JC. PM2.5 associated with gray matter atrophy reflecting increased Alzheimers risk in older women. Neurology. 2020 11 18. PMID: 33208540.
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    19. Rapp SR, Gaussoin SA, Sachs BC, Chelune G, Supiano MA, Lerner AJ, Wadley VG, Wilson VM, Fine LJ, Whittle JC, Auchus AP, Beddhu S, Berlowitz DR, Bress AP, Johnson KC, Krousel-Wood M, Martindale-Adams J, Miller EC, Rifkin DE, Snyder JK, Tamariz L, Wolfgram DF, Cleveland ML, Yang M, Nichols LO, Bryan RN, Reboussin DM, Williamson JD, Pajewski NM. Effects of intensive versus standard blood pressure control on domain-specific cognitive function: a substudy of the SPRINT randomised controlled trial. Lancet Neurol. 2020 11; 19(11):899-907. PMID: 33098800.
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    20. Sachs BC, Steenland K, Zhao L, Hughes TM, Weintraub S, Dodge HH, Barnes LL, Craft S, Parker ML, Goldstein FC. Expanded Demographic Norms for Version 3 of the Alzheimer Disease Centers' Neuropsychological Test Battery in the Uniform Data Set. Alzheimer Dis Assoc Disord. 2020 Jul-Sep; 34(3):191-197. PMID: 32483017.
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    21. Younan D, Petkus AJ, Widaman KF, Wang X, Casanova R, Espeland MA, Gatz M, Henderson VW, Manson JE, Rapp SR, Sachs BC, Serre ML, Gaussoin SA, Barnard R, Saldana S, Vizuete W, Beavers DP, Salinas JA, Chui HC, Resnick SM, Shumaker SA, Chen JC. Particulate matter and episodic memory decline mediated by early neuroanatomic biomarkers of Alzheimer's disease. Brain. 2020 01 01; 143(1):289-302. PMID: 31746986.
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    22. Hayden KM, Gaussoin SA, Hunter JC, Manson JE, Sachs BC, Shadyab AH, Tindle HA, Mossavar-Rahmani Y, Mozhui K, Snively BM, Rapp SR, Resnick SM. Cognitive resilience among APOE e4 carriers in the oldest old. Int J Geriatr Psychiatry. 2019 12; 34(12):1833-1844. PMID: 31418472.
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    23. Nasrallah IM, Pajewski NM, Auchus AP, Chelune G, Cheung AK, Cleveland ML, Coker LH, Crowe MG, Cushman WC, Cutler JA, Davatzikos C, Desiderio L, Doshi J, Erus G, Fine LJ, Gaussoin SA, Harris D, Johnson KC, Kimmel PL, Kurella Tamura M, Launer LJ, Lerner AJ, Lewis CE, Martindale-Adams J, Moy CS, Nichols LO, Oparil S, Ogrocki PK, Rahman M, Rapp SR, Reboussin DM, Rocco MV, Sachs BC, Sink KM, Still CH, Supiano MA, Snyder JK, Wadley VG, Walker J, Weiner DE, Whelton PK, Wilson VM, Woolard N, Wright JT, Wright CB, Williamson JD, Bryan RN. Association of Intensive vs Standard Blood Pressure Control With Cerebral White Matter Lesions. JAMA. 2019 08 13; 322(6):524-534. PMID: 31408137.
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    24. Petkus AJ, Resnick SM, Rapp SR, Espeland MA, Gatz M, Widaman KF, Wang X, Younan D, Casanova R, Chui H, Barnard RT, Gaussoin S, Goveas JS, Hayden KM, Henderson VW, Sachs BC, Saldana S, Shadyab AH, Shumaker SA, Chen JC. General and domain-specific cognitive reserve, mild cognitive impairment, and dementia risk in older women. Alzheimers Dement (N Y). 2019; 5:118-128. PMID: 31011622.
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    25. Williamson JD, Pajewski NM, Auchus AP, Bryan RN, Chelune G, Cheung AK, Cleveland ML, Coker LH, Crowe MG, Cushman WC, Cutler JA, Davatzikos C, Desiderio L, Erus G, Fine LJ, Gaussoin SA, Harris D, Hsieh MK, Johnson KC, Kimmel PL, Tamura MK, Launer LJ, Lerner AJ, Lewis CE, Martindale-Adams J, Moy CS, Nasrallah IM, Nichols LO, Oparil S, Ogrocki PK, Rahman M, Rapp SR, Reboussin DM, Rocco MV, Sachs BC, Sink KM, Still CH, Supiano MA, Snyder JK, Wadley VG, Walker J, Weiner DE, Whelton PK, Wilson VM, Woolard N, Wright JT, Wright CB. Effect of Intensive vs Standard Blood Pressure Control on Probable Dementia: A Randomized Clinical Trial. JAMA. 2019 02 12; 321(6):553-561. PMID: 30688979.
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    26. Wells RE, Kerr C, Dossett ML, Danhauer SC, Sohl SJ, Sachs BC, Feeley JW, Wolkin J, Wall R, Kaptchuk T, Press DZ, Phillips RS, Yeh GY. Can Adults with Mild Cognitive Impairment Build Cognitive Reserve and Learn Mindfulness Meditation? Qualitative Theme Analyses from a Small Pilot Study. J Alzheimers Dis. 2019; 70(3):825-842. PMID: 31282418.
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    27. Espeland MA, Chen JC, Weitlauf J, Hayden KM, Rapp SR, Resnick SM, Garcia L, Cannell B, Baker LD, Sachs BC, Tindle HA, Wallace R, Casanova R. Trajectories of Relative Performance with 2 Measures of Global Cognitive Function. J Am Geriatr Soc. 2018 08; 66(8):1575-1580. PMID: 29972592.
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    28. Sachs BC, Benitez A, Buelow MT, Gooding A, Schaefer LA, Sim AH, Tussey CM, Shear PK. Women's leadership in neuropsychology: historical perspectives, present trends, and future directions. Clin Neuropsychol. 2018 02; 32(2):217-234. PMID: 29376466.
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    29. Gifford AR, Lawrence JA, Baker LD, Balcueva EP, Case D, Craft S, Curtis AE, Griffin L, Groteluschen DL, Klepin HD, Lesser GJ, Messino MJ, Naughton M, Samuel TA, Rapp S, Sachs B, Sink KM, Williamson J, Shaw EG. National Institute on Aging /Alzheimer's Association criteria for Mild Cognitive Impairment applied to chemotherapy treated breast cancer survivors. J Oncol Research. 2017; 1(1). PMID: 29873324.
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    30. Sachs BC, Rush BK, Pedraza O. Validity and reliability of the NAB Naming Test. Clin Neuropsychol. 2016 May; 30(4):629-38. PMID: 27030079.
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    31. Gross AL, Mungas DM, Crane PK, Gibbons LE, MacKay-Brandt A, Manly JJ, Mukherjee S, Romero H, Sachs B, Thomas M, Potter GG, Jones RN. Effects of education and race on cognitive decline: An integrative study of generalizability versus study-specific results. Psychol Aging. 2015 Dec; 30(4):863-880. PMID: 26523693.
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    32. Gross AL, Benitez A, Shih R, Bangen KJ, Glymour MM, Sachs B, Sisco S, Skinner J, Schneider BC, Manly JJ. Predictors of Retest Effects in a Longitudinal Study of Cognitive Aging in a Diverse Community-Based Sample. J Int Neuropsychol Soc. 2015 Aug; 21(7):506-18. PMID: 26527240.
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    33. Bangen KJ, Gu Y, Gross AL, Schneider BC, Skinner JC, Benitez A, Sachs BC, Shih R, Sisco S, Schupf N, Mayeux R, Manly JJ, Luchsinger JA. Relationship Between Type 2 Diabetes Mellitus and Cognitive Change in a Multiethnic Elderly Cohort. J Am Geriatr Soc. 2015 Jun; 63(6):1075-83. PMID: 26096383.
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    34. Dzierzewski JM, Potter GG, Jones RN, Rostant OS, Ayotte B, Yang FM, Sachs BC, Feldman BJ, Steffens DC. Cognitive functioning throughout the treatment history of clinical late-life depression. Int J Geriatr Psychiatry. 2015 Oct; 30(10):1076-84. PMID: 25703072.
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    35. Schneider BC, Gross AL, Bangen KJ, Skinner JC, Benitez A, Glymour MM, Sachs BC, Shih RA, Sisco S, Manly JJ, Luchsinger JA. Association of vascular risk factors with cognition in a multiethnic sample. J Gerontol B Psychol Sci Soc Sci. 2015 Jul; 70(4):532-44. PMID: 24821298.
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    36. Sisco S, Gross AL, Shih RA, Sachs BC, Glymour MM, Bangen KJ, Benitez A, Skinner J, Schneider BC, Manly JJ. The role of early-life educational quality and literacy in explaining racial disparities in cognition in late life. J Gerontol B Psychol Sci Soc Sci. 2015 Jul; 70(4):557-67. PMID: 24584038.
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    37. Sachs BC, Lucas JA, Smith GE, Ivnik RJ, Petersen RC, Graff-Radford NR, Pedraza O. Reliable change on the Boston naming test. J Int Neuropsychol Soc. 2012 Mar; 18(2):375-8. PMID: 22264406.
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    38. Pedraza O, Sachs BC, Ferman TJ, Rush BK, Lucas JA. Difficulty and discrimination parameters of Boston naming test items in a consecutive clinical series. Arch Clin Neuropsychol. 2011 Aug; 26(5):434-44. PMID: 21593059.
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    39. Howe LL, Anderson AM, Kaufman DA, Sachs BC, Loring DW. Characterization of the Medical Symptom Validity Test in evaluation of clinically referred memory disorders clinic patients. Arch Clin Neuropsychol. 2007 Aug; 22(6):753-61. PMID: 17651938.
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    40. Berl MM, Balsamo LM, Xu B, Moore EN, Weinstein SL, Conry JA, Pearl PL, Sachs BC, Grandin CB, Frattali C, Ritter FJ, Sato S, Theodore WH, Gaillard WD. Seizure focus affects regional language networks assessed by fMRI. Neurology. 2005 Nov 22; 65(10):1604-11. PMID: 16301489.
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    41. Ahmad Z, Balsamo LM, Sachs BC, Xu B, Gaillard WD. Auditory comprehension of language in young children: neural networks identified with fMRI. Neurology. 2003 May 27; 60(10):1598-605. PMID: 12771248.
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    42. Sachs BC, Gaillard WD. Organization of language networks in children: functional magnetic resonance imaging studies. Curr Neurol Neurosci Rep. 2003 Mar; 3(2):157-62. PMID: 12583845.
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    43. Gaillard WD, Sachs BC, Whitnah JR, Ahmad Z, Balsamo LM, Petrella JR, Braniecki SH, McKinney CM, Hunter K, Xu B, Grandin CB. Developmental aspects of language processing: fMRI of verbal fluency in children and adults. Hum Brain Mapp. 2003 Mar; 18(3):176-85. PMID: 12599275.
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    44. Gaillard WD, Balsamo LM, Ibrahim Z, Sachs BC, Xu B. fMRI identifies regional specialization of neural networks for reading in young children. Neurology. 2003 Jan 14; 60(1):94-100. PMID: 12525725.
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