"Integrin alpha6beta4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
This intrgrin is a key component of HEMIDESMOSOMES and is required for their formation and maintenance in epithelial cells. Integrin alpha6beta4 is also found on thymocytes, fibroblasts, and Schwann cells, where it functions as a laminin receptor (RECEPTORS, LAMININ) and is involved in wound healing, cell migration, and tumor invasiveness.
| Descriptor ID |
D039161
|
| MeSH Number(s) |
D12.776.543.750.705.408.460.170 D12.776.543.750.705.876.750
|
| Concept/Terms |
Integrin alpha6beta4- Integrin alpha6beta4
- alpha6beta4, Integrin
- alpha(6)beta(4) Epithelial Integrin
- alpha(6)beta(4) Integrin
- Tumor Specific Protein-180 Complex
- Tumor Specific Protein 180 Complex
- Integrin alpha(6),beta(4)
- Laminin-5 Receptor (alpha6beta4 Integrin)
- TSP-180
- A9 Antigen
- Antigen, A9
- alpha6 beta4 Integrin
- Integrin, alpha6 beta4
- beta4 Integrin, alpha6
|
Below are MeSH descriptors whose meaning is more general than "Integrin alpha6beta4".
Below are MeSH descriptors whose meaning is more specific than "Integrin alpha6beta4".
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
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Below are the most recent publications written about "Integrin alpha6beta4" by people in Profiles.