Receptor, Epidermal Growth Factor
"Receptor, Epidermal Growth Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cell surface receptor involved in regulation of cell growth and differentiation. It is specific for EPIDERMAL GROWTH FACTOR and EGF related peptides including TRANSFORMING GROWTH FACTOR ALPHA, amphiregulin, and heparin-binding EGF-like growth factor. The binding of ligand to the receptor causes activation of its intrinsic tyrosine kinase activity and rapid internalization of the receptor-ligand complex into the cell.
| Descriptor ID |
D011958
|
| MeSH Number(s) |
D08.811.913.696.620.682.725.400.100 D12.776.543.750.060.249 D12.776.543.750.750.360.300 D12.776.543.750.750.400.340
|
| Concept/Terms |
Receptor, Epidermal Growth Factor- Receptor, Epidermal Growth Factor
- EGF Receptor
- Epidermal Growth Factor Receptor
- Epidermal Growth Factor Receptor Kinase
- Epidermal Growth Factor Receptor Protein-Tyrosine Kinase
- Epidermal Growth Factor Receptor Protein Tyrosine Kinase
- erbB-1 Proto-Oncogene Protein
- Proto-Oncogene Protein, erbB-1
- erbB 1 Proto Oncogene Protein
- Receptor, EGF
- Receptor, TGF-alpha
- Receptor, TGF alpha
- Receptor, Transforming-Growth Factor alpha
- Receptor, Transforming Growth Factor alpha
- Receptor, Urogastrone
- Receptors, Epidermal Growth Factor
- Receptors, Epidermal Growth Factor-Urogastrone
- Receptors, Epidermal Growth Factor Urogastrone
- TGF-alpha Receptor
- Transforming Growth Factor alpha Receptor
- Urogastrone Receptor
- c-erbB-1 Protein
- c erbB 1 Protein
|
Below are MeSH descriptors whose meaning is more general than "Receptor, Epidermal Growth Factor".
- Chemicals and Drugs [D]
- Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
- Transferases [D08.811.913]
- Phosphotransferases [D08.811.913.696]
- Phosphotransferases (Alcohol Group Acceptor) [D08.811.913.696.620]
- Protein Kinases [D08.811.913.696.620.682]
- Protein-Tyrosine Kinases [D08.811.913.696.620.682.725]
- Receptor Protein-Tyrosine Kinases [D08.811.913.696.620.682.725.400]
- Receptor, Epidermal Growth Factor [D08.811.913.696.620.682.725.400.100]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptor Protein-Tyrosine Kinases [D12.776.543.750.060]
- Receptor, Epidermal Growth Factor [D12.776.543.750.060.249]
- Receptors, Peptide [D12.776.543.750.750]
- Receptors, Gastrointestinal Hormone [D12.776.543.750.750.360]
- Receptor, Epidermal Growth Factor [D12.776.543.750.750.360.300]
- Receptors, Growth Factor [D12.776.543.750.750.400]
- Receptor, Epidermal Growth Factor [D12.776.543.750.750.400.340]
Below are MeSH descriptors whose meaning is more specific than "Receptor, Epidermal Growth Factor".
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