Cyclic Nucleotide Phosphodiesterases, Type 3
"Cyclic Nucleotide Phosphodiesterases, Type 3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
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A cyclic nucleotide phosphodiesterase subfamily that is inhibited by the binding of CYCLIC GMP to an allosteric domain found on the enzyme and through phosphorylation by regulatory kinases such as PROTEIN KINASE A and PROTEIN KINASE B. The two members of this family are referred to as type 3A, and type 3B, and are each product of a distinct gene. In addition multiple enzyme variants of each subtype can be produced due to multiple alternative mRNA splicing.
| Descriptor ID |
D054684
|
| MeSH Number(s) |
D08.811.277.352.640.150.300 D12.644.360.008.300 D12.776.476.008.300
|
| Concept/Terms |
Cyclic Nucleotide Phosphodiesterases, Type 3- Cyclic Nucleotide Phosphodiesterases, Type 3
- Phosphodiesterase III
- Cyclic Nucleotide Phosphodiesterase PDE3 Family
- cGMP-Inhibited Cyclic Nucleotide Phosphodiesterase
- cGMP Inhibited Cyclic Nucleotide Phosphodiesterase
- cGMP-Inhibited Phosphodiesterase
- Phosphodiesterase, cGMP-Inhibited
- cGMP Inhibited Phosphodiesterase
|
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
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