Proto-Oncogene Proteins c-bcr
"Proto-Oncogene Proteins c-bcr" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
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Proto-oncogene protein bcr is a serine-threonine kinase that functions as a negative regulator of CELL PROLIFERATION and NEOPLASTIC CELL TRANSFORMATION. It is commonly fused with cellular abl protein to form BCR-ABL FUSION PROTEINS in PHILADELPHIA CHROMOSOME positive LEUKEMIA patients.
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