The FGFR/MEK/ERK/brachyury pathway is critical for chordoma cell growth and survival.

Hu Y, Mintz A, Shah SR, Quinones-Hinojosa A, Hsu W. The FGFR/MEK/ERK/brachyury pathway is critical for chordoma cell growth and survival. Carcinogenesis. 2014 Jul; 35(7):1491-9.

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subject areas

Apoptosis
Blotting, Western
Cell Movement
Cell Proliferation
Cells, Cultured
Chordoma
Fetal Proteins
Fibroblast Growth Factor 2
Fibroblasts
Fluorescent Antibody Technique
Humans
MAP Kinase Kinase 1
Mitogen-Activated Protein Kinase 1
Mitogen-Activated Protein Kinase 3
Phosphorylation
Receptor, Fibroblast Growth Factor, Type 1
Reverse Transcriptase Polymerase Chain Reaction
RNA, Messenger
Signal Transduction
T-Box Domain Proteins

authors with profiles

Wesley Hsu MD, FAACS