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Allosteric RegulationConcept Why?
Acute Negative Allosteric Modulation of M5 Muscarinic Acetylcholine Receptors Inhibits Oxycodone Self-Administration and Cue-Induced Reactivity with No Effect on Antinociception.Academic Article Why?
Gould, RobertPerson Why?
Biased mGlu5-Positive Allosteric Modulators Provide In Vivo Efficacy without Potentiating mGlu5 Modulation of NMDAR Currents.Academic Article Why?
Long-term ethanol self-administration by the nonhuman primate, Macaca fascicularis, decreases the benzodiazepine sensitivity of amygdala GABA(A) receptors.Academic Article Why?
Repeated dosing with oral allosteric modulator of adenosine A1 receptor produces tolerance in rats with neuropathic pain.Academic Article Why?
Selective allosteric modulation of muscarinic acetylcholine receptors for the treatment of schizophrenia and substance use disorders.Academic Article Why?
State-dependent alterations in sleep/wake architecture elicited by the M4 PAM VU0467154 - Relation to antipsychotic-like drug effects.Academic Article Why?
Allosteric modulation of adenosine A1 receptor coupling to G-proteins in brain.Academic Article Why?
Cognitive enhancement and antipsychotic-like activity following repeated dosing with the selective M4 PAM VU0467154.Academic Article Why?
Partial mGlu5 Negative Allosteric Modulators Attenuate Cocaine-Mediated Behaviors and Lack Psychotomimetic-Like Effects.Academic Article Why?
Eisenach, JamesPerson Why?
Spinal noradrenergic activation mediates allodynia reduction from an allosteric adenosine modulator in a rat model of neuropathic pain.Academic Article Why?
McCool, BrianPerson Why?
Daunais, JamesPerson Why?
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