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Decreased cardiac Ang-(1-7) is associated with salt-induced cardiac remodeling and dysfunction.
Uptake and metabolism of the novel peptide angiotensin-(1-12) by neonatal cardiac myocytes.
Salt-induced renal injury in spontaneously hypertensive rats: effects of nebivolol.
Nebivolol reduces cardiac angiotensin II, associated oxidative stress and fibrosis but not arterial pressure in salt-loaded spontaneously hypertensive rats.
Rats, Inbred SHR
Primacy of angiotensin converting enzyme in angiotensin-(1-12) metabolism.
Primacy of cardiac chymase over angiotensin converting enzyme as an angiotensin-(1-12) metabolizing enzyme.
Blunting of cardioprotective actions of estrogen in female rodent heart linked to altered expression of cardiac tissue chymase and ACE2.
Blunting of estrogen modulation of cardiac cellular chymase/RAS activity and function in SHR.
Estrogen modulates the differential expression of cardiac myocyte chymase isoforms and diastolic function.
G-Protein-Coupled Estrogen Receptor Agonist G1 Improves Diastolic Function and Attenuates Cardiac Renin-Angiotensin System Activation in Estrogen-Deficient Hypertensive Rats.
Amplifying effect of chronic lisinopril therapy on diastolic function and the angiotensin-(1-7) Axis by the G1 agonist in ovariectomized spontaneously hypertensive rats.
Rats Inbred SHR