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One or more keywords matched the following properties of Tomar, Dhanendra
overview Current Projects: Mitochondrial Ultrastructural Remodeling and Inter-Organelles Crosstalk: We aim to identify the molecular determinants, and signaling events associated with mitochondrial contact sites and mitochondrial membranes architecture. Protein Quality Control: Our research aims to identify the molecular determinants of the mitochondrial protein quality control mechanisms and delineate the associated molecular events that lead to disease onset. Calcium signaling and mitochondrial ionic homeostasis: We aim to identify the new regulators and regulatory events associated with mitochondrial calcium-sensing/flux and their role in animal physiology using protein biochemistry, high-end imaging-based approaches, and genetic manipulations. Cardiac Physiology & Metabolism: We aim to characterize the molecular regulators and events involved in cardiac physiology and metabolism using mouse genetics and physiology-based in vivo methods.
One or more keywords matched the following items that are connected to Tomar, Dhanendra
Item TypeName
Concept X-Linked Inhibitor of Apoptosis Protein
Concept Ubiquitin-Protein Ligases
Concept Protein Multimerization
Concept Protein Structure, Quaternary
Concept Protein Biosynthesis
Concept Receptors, G-Protein-Coupled
Concept Protein Kinases
Concept Protein Interaction Domains and Motifs
Concept Early Growth Response Protein 1
Concept Protein Binding
Concept Protein Transport
Concept Protein Folding
Concept Protein Inhibitors of Activated STAT
Concept Protein Processing, Post-Translational
Concept Unfolded Protein Response
Concept Protein Conformation
Academic Article Metabolite regulation of the mitochondrial calcium uniporter channel.
Academic Article Mitochondrial Protein Quality Control Mechanisms.
Academic Article Context-Dependent Regulation of Nrf2/ARE Axis on Vascular Cell Function during Hyperglycemic Condition.
Academic Article Impaired mitochondrial calcium efflux contributes to disease progression in models of Alzheimer's disease.
Academic Article Mitochondrial dysfunction in human primary alveolar type II cells in emphysema.
Academic Article The relationship between DJ-1 and S100A8 in human primary alveolar type II cells in emphysema.
Academic Article The role of DJ-1 in human primary alveolar type II cell injury induced by e-cigarette aerosol.
Academic Article The central role of protein kinase C epsilon in cyanide cardiotoxicity and its treatment.
Academic Article Blockade of MCU-Mediated Ca2+ Uptake Perturbs Lipid Metabolism via PP4-Dependent AMPK Dephosphorylation.
Academic Article MIRO-1 Determines Mitochondrial Shape Transition upon GPCR Activation and Ca2+ Stress.
Academic Article TRIM8 regulated autophagy modulates the level of cleaved Caspase-3 subunit to inhibit genotoxic stress induced cell death.
Academic Article Egr-1 mediated cardiac miR-99 family expression diverges physiological hypertrophy from pathological hypertrophy.
Academic Article Mitochondrial Ca2+ Uniporter Is a Mitochondrial Luminal Redox Sensor that Augments MCU Channel Activity.
Academic Article Structural Insights into Mitochondrial Calcium Uniporter Regulation by Divalent Cations.
Academic Article MCUR1 Is a Scaffold Factor for the MCU Complex Function and Promotes Mitochondrial Bioenergetics.
Academic Article NLRX1 acts as tumor suppressor by regulating TNF-a induced apoptosis and metabolism in cancer cells.
Academic Article TRIM family proteins: emerging class of RING E3 ligases as regulator of NF-?B pathway.
Academic Article TRIM13 regulates ubiquitination and turnover of NEMO to suppress TNF induced NF-?B activation.
Academic Article Antiviral signaling protein MITA acts as a tumor suppressor in breast cancer by regulating NF-?B induced cell death.
Academic Article TRIM13 regulates caspase-8 ubiquitination, translocation to autophagosomes and activation during ER stress induced cell death.
Academic Article Nucleo-cytoplasmic trafficking of TRIM8, a novel oncogene, is involved in positive regulation of TNF induced NF-?B pathway.
Academic Article TRIM13 regulates ER stress induced autophagy and clonogenic ability of the cells.
Grant Impact of mitochondrial structure on cellular homeostasis and hepatic injury
Grant Mitochondrial inter-membrane space protein quality control in Barth syndrome-associated cardiomyopathy
Grant Mitochondrial protein quality control and calcium signaling in myocardial ischemia-reperfusion injury
Academic Article Suppression of Ca2+ signaling enhances melanoma progression.
Grant Mitochondrial protein quality control and Ca2+ flux in Alzheimer's Disease
Academic Article Post-translational modifications and protein quality control of mitochondrial channels and transporters.
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