| Item Type | Name |
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Concept
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Analgesics, Opioid
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Concept
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Analgesics, Non-Narcotic
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Concept
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Analgesics
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Academic Article
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Long-lasting antinociceptive spinal effects in primates of the novel nociceptin/orphanin FQ receptor agonist UFP-112.
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Academic Article
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Effects of spinally administered bifunctional nociceptin/orphanin FQ peptide receptor/µ-opioid receptor ligands in mouse models of neuropathic and inflammatory pain.
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Academic Article
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Pharmacological, pharmacokinetic, and primate analgesic efficacy profile of the novel bradykinin B1 Receptor antagonist ELN441958.
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Academic Article
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Antinociceptive effects of nociceptin/orphanin FQ administered intrathecally in monkeys.
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Academic Article
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Behavioral effects of a synthetic agonist selective for nociceptin/orphanin FQ peptide receptors in monkeys.
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Academic Article
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The therapeutic potential of nociceptin/orphanin FQ receptor agonists as analgesics without abuse liability.
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Academic Article
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Effects of butorphanol on morphine-induced itch and analgesia in primates.
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Academic Article
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Effects of mu, kappa, and delta opioid receptor agonists on the function of hypothalamic-pituitary-adrenal axis in monkeys.
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Academic Article
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The spinal antinociceptive effects of endomorphins in rats: behavioral and G protein functional studies.
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Academic Article
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Differential effects of opioid-related ligands and NSAIDs in nonhuman primate models of acute and inflammatory pain.
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Academic Article
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[Dmt1]N/OFQ(1-13)-NH2: a potent nociceptin/orphanin FQ and opioid receptor universal agonist.
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Academic Article
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Effects of intrathecally administered nociceptin/orphanin FQ in monkeys: behavioral and mass spectrometric studies.
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Academic Article
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Endogenous opioids upregulate brain-derived neurotrophic factor mRNA through delta- and micro-opioid receptors independent of antidepressant-like effects.
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Academic Article
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Antinociceptive, hypothermic, hypotensive, and reinforcing effects of a novel neurotensin receptor agonist, NT69L, in rhesus monkeys.
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Academic Article
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Characterization of the complex morphinan derivative BU72 as a high efficacy, long-lasting mu-opioid receptor agonist.
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Academic Article
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The role of central mu opioid receptors in opioid-induced itch in primates.
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Academic Article
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Characterization of scratching responses in rats following centrally administered morphine or bombesin.
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Academic Article
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Activation of kappa-opioid receptors inhibits pruritus evoked by subcutaneous or intrathecal administration of morphine in monkeys.
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Academic Article
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Relative reinforcing effects of three opioids with different durations of action.
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Academic Article
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Functional plasticity of the N/OFQ-NOP receptor system determines analgesic properties of NOP receptor agonists.
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Academic Article
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Neuraxial opioid-induced itch and its pharmacological antagonism.
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Academic Article
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Distinct functions of opioid-related peptides and gastrin-releasing peptide in regulating itch and pain in the spinal cord of primates.
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Academic Article
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TC-2559, an a4ß2 nicotinic acetylcholine receptor agonist, suppresses the expression of CCL3 and IL-1ß through STAT3 inhibition in cultured murine macrophages.
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Academic Article
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Central N/OFQ-NOP Receptor System in Pain Modulation.
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Academic Article
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Spinal antinociceptive effects of the novel NOP receptor agonist PWT2-nociceptin/orphanin FQ in mice and monkeys.
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Academic Article
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GR89,696: a potent kappa-opioid agonist with subtype selectivity in rhesus monkeys.
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Academic Article
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Diltiazem enhances the analgesic but not the respiratory depressant effects of morphine in rhesus monkeys.
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Academic Article
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An experimental itch model in monkeys: characterization of intrathecal morphine-induced scratching and antinociception.
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Academic Article
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Local administration of mu or kappa opioid agonists attenuates capsaicin-induced thermal hyperalgesia via peripheral opioid receptors in rats.
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Academic Article
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Activation of peripheral kappa opioid receptors inhibits capsaicin-induced thermal nociception in rhesus monkeys.
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Academic Article
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Local administration of delta9-tetrahydrocannabinol attenuates capsaicin-induced thermal nociception in rhesus monkeys: a peripheral cannabinoid action.
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Academic Article
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Intracisternal nor-binaltorphimine distinguishes central and peripheral kappa-opioid antinociception in rhesus monkeys.
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Academic Article
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Differentiation of kappa opioid agonist-induced antinociception by naltrexone apparent pA2 analysis in rhesus monkeys.
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Academic Article
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kappa-Opioid receptor binding populations in rhesus monkey brain: relationship to an assay of thermal antinociception.
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Academic Article
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A novel orvinol analog, BU08028, as a safe opioid analgesic without abuse liability in primates.
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Academic Article
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A bifunctional nociceptin and mu opioid receptor agonist is analgesic without opioid side effects in nonhuman primates.
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Academic Article
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Effects of NOP-Related Ligands in Nonhuman Primates.
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Academic Article
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Antinociceptive, reinforcing, and pruritic effects of the G-protein signalling-biased mu opioid receptor agonist PZM21 in non-human primates.
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Academic Article
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Nociceptin/Orphanin FQ Peptide Receptor-Related Ligands as Novel Analgesics.
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Academic Article
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Functional consequences of short-term exposure to opioids versus cannabinoids in nonhuman primates.
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Academic Article
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Potential therapeutic targets for the treatment of opioid abuse and pain.
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Academic Article
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[Therapeutic potentials of safe opioid analgesics targeting nociceptin/orphanin FQ peptide receptor].
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Academic Article
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Enhanced antidepressant-like effects of a delta opioid receptor agonist, SNC80, in rats under inflammatory pain.
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Academic Article
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Nociceptin Receptor-Related Agonists as Safe and Non-addictive Analgesics.
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