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One or more keywords matched the following properties of Lockhart, Samuel
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keywords Amyloid Plaques
overview Samuel N. Lockhart, Ph.D., is a neuroscientist who has spent his research career disentangling normal brain aging from preclinical disease. He earned his Ph.D. in Neuroscience from UC Davis with Dr. Charles DeCarli, investigating the impacts of age and cerebrovascular disease on brain function and cognition, and completed a postdoctoral fellowship with Dr. William Jagust at UC Berkeley, examining how tau and amyloid accumulation affect brain structure and cognitive trajectories. He is an author of publications that have appeared in Neuron, NeuroImage, Neurology, Journal of Neuroscience, Brain, Stroke, Journal of Nuclear Medicine, and JAMA Neurology, among others. At Wake Forest, Dr. Lockhart is an Associate Professor of Internal Medicine and Gerontology and Geriatric Medicine. He plans to build a research program in multimodal neuroimaging and cognitive analyses of aging and diseases of aging, with a focus on interactions between metabolic dysfunction and vascular and degenerative pathology.
One or more keywords matched the following items that are connected to Lockhart, Samuel
Item TypeName
Concept Amyloid
Academic Article Tau and ß-Amyloid Are Associated with Medial Temporal Lobe Structure, Function, and Memory Encoding in Normal Aging.
Academic Article Amyloid and tau PET demonstrate region-specific associations in normal older people.
Academic Article Comparison of multiple tau-PET measures as biomarkers in aging and Alzheimer's disease.
Academic Article Elevated 18F-AV-1451 PET tracer uptake detected in incidental imaging findings.
Academic Article Alzheimer Disease Signature Neurodegeneration and APOE Genotype in Mild Cognitive Impairment With Suspected Non-Alzheimer Disease Pathophysiology.
Academic Article Tau PET patterns mirror clinical and neuroanatomical variability in Alzheimer's disease.
Academic Article Diagonal Earlobe Crease is a Visible Sign for Cerebral Small Vessel Disease and Amyloid-ß.
Academic Article Local and distant relationships between amyloid, tau and neurodegeneration in Alzheimer's Disease.
Academic Article Entorhinal Tau Pathology, Episodic Memory Decline, and Neurodegeneration in Aging.
Academic Article Centiloid method evaluation for amyloid PET of subcortical vascular dementia.
Academic Article Subthreshold Amyloid Predicts Tau Deposition in Aging.
Academic Article Relationships Between Tau and Glucose Metabolism Reflect Alzheimer's Disease Pathology in Cognitively Normal Older Adults.
Academic Article Amyloid involvement in subcortical regions predicts cognitive decline.
Academic Article A Nomogram for Predicting Amyloid PET Positivity in Amnestic Mild Cognitive Impairment.
Academic Article Multisite study of the relationships between antemortem [11C]PIB-PET Centiloid values and postmortem measures of Alzheimer's disease neuropathology.
Academic Article Distinct amyloid distribution patterns in amyloid positive subcortical vascular cognitive impairment.
Grant Biomarkers of preclinical Alzheimer disease and cognition
Academic Article Vascular dysfunction-The disregarded partner of Alzheimer's disease.
Academic Article Prediction of fast decline in amyloid positive mild cognitive impairment patients using multimodal biomarkers.
Academic Article Application of an amyloid and tau classification system in subcortical vascular cognitive impairment patients.
Academic Article Modified ketogenic diet is associated with improved cerebrospinal fluid biomarker profile, cerebral perfusion, and cerebral ketone body uptake in older adults at risk for Alzheimer's disease: a pilot study.
Academic Article T cell exhaustion is associated with cognitive status and amyloid accumulation in Alzheimer's disease.
Academic Article Age and beta amyloid deposition impact gait speed, stride length, and gait smoothness while transitioning from an even to an uneven walking surface in older adults.
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  • Amyloid