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Powell, Jason
One or more keywords matched the following items that are connected to Powell, Jason
Item TypeName
Concept MAP Kinase Signaling System
Concept Phosphotransferases (Alcohol Group Acceptor)
Concept Protein Kinase Inhibitors
Concept Cyclic AMP-Dependent Protein Kinases
Concept Cyclin-Dependent Kinase 9
Concept Protein Kinase C-epsilon
Concept fms-Like Tyrosine Kinase 3
Academic Article Growth factor pleiotropy is controlled by a receptor Tyr/Ser motif that acts as a binary switch.
Academic Article Protein kinase activity of phosphoinositide 3-kinase regulates cytokine-dependent cell survival.
Academic Article Phosphorylation of serine 779 in fibroblast growth factor receptor 1 and 2 by protein kinase C(epsilon) regulates Ras/mitogen-activated protein kinase signaling and neuronal differentiation.
Academic Article Sphingosine kinase 2 promotes acute lymphoblastic leukemia by enhancing MYC expression.
Academic Article Regulation of sphingosine kinase in hematological malignancies and other cancers.
Academic Article Targeting acute myeloid leukemia by dual inhibition of PI3K signaling and Cdk9-mediated Mcl-1 transcription.
Academic Article 14-3-3:Shc scaffolds integrate phosphoserine and phosphotyrosine signaling to regulate phosphatidylinositol 3-kinase activation and cell survival.
Academic Article Expression profiling of a hemopoietic cell survival transcriptome implicates osteopontin as a functional prognostic factor in AML.
Academic Article A selective ATP-competitive sphingosine kinase inhibitor demonstrates anti-cancer properties.
Academic Article Activation of protein phosphatase 2A in FLT3+ acute myeloid leukemia cells enhances the cytotoxicity of FLT3 tyrosine kinase inhibitors.
Academic Article Targeting sphingosine kinase 1 induces MCL1-dependent cell death in acute myeloid leukemia.
Academic Article An oncogenic role for sphingosine kinase 2.
Academic Article Inhibition of Pol I transcription treats murine and human AML by targeting the leukemia-initiating cell population.
Academic Article Identification of sphingosine kinase 1 as a therapeutic target in B-lineage acute lymphoblastic leukaemia.
Academic Article Cytoplasmic dynein regulates the subcellular localization of sphingosine kinase 2 to elicit tumor-suppressive functions in glioblastoma.
Academic Article Targeting sphingosine kinase 1 in acute myeloid leukemia: translation to clinic.
Academic Article Kelch-like protein 5-mediated ubiquitination of lysine 183 promotes proteasomal degradation of sphingosine kinase 1.
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  • Phosphotransferases