First Header Logo Second Header Logo

Search Result Details

This page shows the details of why an item matched the keywords from your search.
One or more keywords matched the following items that are connected to Hollis, Thomas
Item TypeName
Academic Article Essential amino acid residues in the single-stranded DNA-binding protein of bacteriophage T7. Identification of the dimer interface.
Academic Article The human TREX2 3' -> 5'-exonuclease structure suggests a mechanism for efficient nonprocessive DNA catalysis.
Academic Article Crystallization of protein-DNA complexes.
Academic Article A mutation in TREX1 that impairs susceptibility to granzyme A-mediated cell death underlies familial chilblain lupus.
Academic Article Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 are associated with systemic lupus erythematosus.
Academic Article Small molecule induction of MSH2-dependent cell death suggests a vital role of mismatch repair proteins in cell death.
Academic Article Structural and mutational analysis of Escherichia coli AlkB provides insight into substrate specificity and DNA damage searching.
Academic Article The TREX1 exonuclease R114H mutation in Aicardi-Goutières syndrome and lupus reveals dimeric structure requirements for DNA degradation activity.
Academic Article The transcription factor AmrZ utilizes multiple DNA binding modes to recognize activator and repressor sequences of Pseudomonas aeruginosa virulence genes.
Academic Article Crystallization of Pseudomonas aeruginosa AmrZ protein: development of a comprehensive method for obtaining and optimization of protein-DNA crystals.
Academic Article The molecular mechanism of DNA damage recognition by MutS homologs and its consequences for cell death response.
Academic Article The crystal structure of TREX1 explains the 3' nucleotide specificity and reveals a polyproline II helix for protein partnering.
Academic Article Heterozygous mutations in TREX1 cause familial chilblain lupus and dominant Aicardi-Goutieres syndrome.
Academic Article DNA damage recognition and repair by 3-methyladenine DNA glycosylase I (TAG).
Academic Article Cooperative DNA binding and communication across the dimer interface in the TREX2 3' --> 5'-exonuclease.
Academic Article The TREX1 double-stranded DNA degradation activity is defective in dominant mutations associated with autoimmune disease.
Academic Article Lesion bypass of N2-ethylguanine by human DNA polymerase iota.
Academic Article DNA binding induces active site conformational change in the human TREX2 3'-exonuclease.
Academic Article The structure of the mammalian RNase H2 complex provides insight into RNA.NA hybrid processing to prevent immune dysfunction.
Academic Article AmrZ beta-sheet residues are essential for DNA binding and transcriptional control of Pseudomonas aeruginosa virulence genes.
Academic Article Dominant mutation of the TREX1 exonuclease gene in lupus and Aicardi-Goutieres syndrome.
Academic Article Defects in DNA degradation revealed in crystal structures of TREX1 exonuclease mutations linked to autoimmune disease.
Concept DNA, Bacterial
Concept DNA Damage
Concept DNA-Directed DNA Polymerase
Concept DNA Polymerase III
Concept MutS DNA Mismatch-Binding Protein
Concept DNA
Concept DNA Glycosylases
Concept DNA Primers
Concept DNA Mismatch Repair
Concept DNA Adducts
Concept DNA Mutational Analysis
Concept Sequence Analysis, DNA
Concept DNA-Binding Proteins
Concept DNA Replication
Concept DNA Repair
Concept DNA, Single-Stranded
Academic Article The Arg-62 residues of the TREX1 exonuclease act across the dimer interface contributing to catalysis in the opposing protomers.
Academic Article Cationic antimicrobial peptides promote microbial mutagenesis and pathoadaptation in chronic infections.
Academic Article Crystal structure of RNA-DNA duplex provides insight into conformational changes induced by RNase H binding.
Academic Article Exonuclease TREX1 degrades double-stranded DNA to prevent spontaneous lupus-like inflammatory disease.
Academic Article Solid-State Nanopore Analysis of Diverse DNA Base Modifications Using a Modular Enzymatic Labeling Process.
Grant Structure and Regulation of the TREX1 Exonuclease
Search Criteria
  • DNA