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Hollis, Thomas
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Hollis, Thomas
Item Type
Name
Academic Article
The crystal structure of TREX1 explains the 3' nucleotide specificity and reveals a polyproline II helix for protein partnering.
Academic Article
The structure of the mammalian RNase H2 complex provides insight into RNA.NA hybrid processing to prevent immune dysfunction.
Concept
Autoimmunity
Academic Article
Exonuclease TREX1 degrades double-stranded DNA to prevent spontaneous lupus-like inflammatory disease.
Academic Article
SAMHD1: Recurring roles in cell cycle, viral restriction, cancer, and innate immunity.
Search Criteria
Autoimmunity