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One or more keywords matched the following items that are connected to Gmeiner, William
Item TypeName
Academic Article Intramolecular binding of a proximal PPII helix to an SH3 domain in the fusion protein SH3Hck : PPIIhGAP.
Academic Article The structure and dynamics of the U4/U6 snRNP: implications for pre-mRNA splicing and use as a model system to investigate the RNA-mediated effects of (5F)Ura.
Academic Article Effect of 5-FU substitution and mutation on Sm protein binding to human U4 snRNA.
Academic Article A linear 23-residue peptide reveals a propensity to form an unusual native-like conformation.
Academic Article Three-dimensional structure of the Hck SH2 domain in solution.
Academic Article Identification and localization of slow, natural, cooperative unfolding in the hematopoietic cell kinase SH3 domain by amide hydrogen exchange and mass spectrometry.
Academic Article Solution structure of the human Hck SH3 domain and identification of its ligand binding site.
Academic Article Structure of the Sm binding site from human U4 snRNA derived from a 3 ns PME molecular dynamics simulation.
Academic Article Molecular dynamics simulation of the human U2B" protein complex with U2 snRNA hairpin IV in aqueous solution.
Academic Article Implications of SH3 domain structure and dynamics for protein regulation and drug design.
Academic Article Improved 3D gd-HCACO and gd-(H)CACO-TOCSY experiments for isotopically enriched proteins dissolved in H2O.
Academic Article A 3D NOESY-(HCACO)NH experiment for the measurement of NOEs involving 1H alpha in 13C/15N-labeled proteins dissolved in H2O.
Academic Article Sequential assignment and secondary structure determination for the Src homology 2 domain of hematopoietic cellular kinase.
Academic Article Self-association and backbone dynamics of the hck SH2 domain in the free and phosphopeptide-complexed forms.
Academic Article Comparison of SH3 and SH2 domain dynamics when expressed alone or in an SH(3+2) construct: the role of protein dynamics in functional regulation.
Academic Article Hydrogen exchange shows peptide binding stabilizes motions in Hck SH2.
Academic Article Dynamics of the Hck-SH3 domain: comparison of experiment with multiple molecular dynamics simulations.
Academic Article Antineoplastic activity of a novel multimeric gemcitabine-monophosphate prodrug against thyroid cancer cells in vitro.
Concept BRCA1 Protein
Concept Protein Structure, Tertiary
Concept Protein Kinase Inhibitors
Concept Protein Denaturation
Concept Protein Structure, Secondary
Concept Protein-Tyrosine Kinases
Concept Protein Binding
Concept Protein Folding
Concept Fas Ligand Protein
Concept Protein Conformation
Academic Article Thymineless death in F10-treated AML cells occurs via lipid raft depletion and Fas/FasL co-localization in the plasma membrane with activation of the extrinsic apoptotic pathway.
Academic Article Importance of long-time simulations for rare event sampling in zinc finger proteins.
Academic Article Binding Site Configurations Probe the Structure and Dynamics of the Zinc Finger of NEMO (NF-?B Essential Modulator).
Academic Article All-atom molecular dynamics comparison of disease-associated zinc fingers.
Grant Aptamer-Based Radiopharmaceuticals for the Targeted Alpha Particle Therapy of Prostate Cancer
Academic Article Thymineless Death by the Fluoropyrimidine Polymer F10 Involves Replication Fork Collapse and Is Enhanced by Chk1 Inhibition.
Academic Article Prexasertib treatment induces homologous recombination deficiency and synergizes with olaparib in triple-negative breast cancer cells.
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