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Gmeiner, William

One or more keywords matched the following items that are connected to Gmeiner, William

Item Type	Name
Academic Article	Targeted drug delivery to chemoresistant cells: folic acid derivatization of FdUMP[10] enhances cytotoxicity toward 5-FU-resistant human colorectal tumor cells.
Academic Article	The structure and dynamics of the U4/U6 snRNP: implications for pre-mRNA splicing and use as a model system to investigate the RNA-mediated effects of (5F)Ura.
Academic Article	Effect of 5-FU substitution and mutation on Sm protein binding to human U4 snRNA.
Academic Article	Novel chemical strategies for thymidylate synthase inhibition.
Academic Article	Genome-wide mRNA and microRNA profiling of the NCI 60 cell-line screen and comparison of FdUMP[10] with fluorouracil, floxuridine, and topoisomerase 1 poisons.
Academic Article	Effects of site-specific substitution of 5-fluorouridine on the stabilities of duplex DNA and RNA.
Academic Article	Solution structures of 5-fluorouracil-substituted DNA and RNA decamer duplexes.
Academic Article	The 5' stem-loop from human U4 snRNA adopts a novel conformation stabilized by G-C and G-U base pairs.
Academic Article	NMR spectroscopy as a tool to investigate the structural basis of anticancer drugs.
Academic Article	Structure of the Sm binding site from human U4 snRNA derived from a 3 ns PME molecular dynamics simulation.
Academic Article	Molecular dynamics simulation of the human U2B" protein complex with U2 snRNA hairpin IV in aqueous solution.
Academic Article	Energetic and conformational contributions to the stability of Okazaki fragments.
Academic Article	The affinity of an oligodeoxynucleotide-peptide conjugate for an RNA hairpin loop depends on stereochemistry at the DNA-peptide junction.
Academic Article	Solution structures of 5-fluorouracil-substituted RNA duplexes containing G-U wobble base pairs.
Academic Article	Polarity of annealing and structural analysis of the RNase H resistant alpha-5'-d[TACACA].beta-5'-r[AUGUGU] hybrid determined by high-field 1H, 13C, and 31P NMR analysis.
Concept	RNA, Messenger
Concept	RNA
Concept	RNA, Small Nuclear
Concept	RNA, Small Interfering
Concept	RNA Splicing
Concept	RNA-Binding Proteins
Concept	RNA, Double-Stranded
Academic Article	Development of modified siRNA molecules incorporating 5-fluoro-2'-deoxyuridine residues to enhance cytotoxicity.
Grant	IMPACT OF 5-FU ON THE STRUCTURE OF THE U4-U6 COMPLEX
Grant	IMPACT OF 5FU ON THE STRUCTURE OF THE U4/U6 COMPLEX
Academic Article	All-Atom MD Predicts Magnesium-Induced Hairpin in Chemically Perturbed RNA Analog of F10 Therapeutic.

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