Item Type | Name |
Academic Article
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Peptide requirement for CTL activation reflects the sensitivity to CD3 engagement: correlation with CD8alphabeta versus CD8alphaalpha expression.
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Academic Article
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A novel CD8-independent high-avidity cytotoxic T-lymphocyte response directed against an epitope in the phosphoprotein of the paramyxovirus simian virus 5.
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Academic Article
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Spontaneous regression of advanced cancer: identification of a unique genetically determined, age-dependent trait in mice.
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Academic Article
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High avidity CD8+ T cells generated from CD28-deficient or wildtype mice exhibit a differential dependence on lipid raft integrity for activation.
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Academic Article
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Modulation of CD8+ T cell avidity by increasing the turnover of viral antigen during infection.
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Academic Article
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Abortive versus productive viral infection of dendritic cells with a paramyxovirus results in differential upregulation of select costimulatory molecules.
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Academic Article
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Transferable anticancer innate immunity in spontaneous regression/complete resistance mice.
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Academic Article
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Vaccinia virus infection of mature dendritic cells results in activation of virus-specific naïve CD8+ T cells: a potential mechanism for direct presentation.
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Academic Article
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Distinct pathways for signaling maturation in macrophages and dendritic cells after infection with paramyxovirus simian virus 5.
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Academic Article
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Cutting edge: CD8+ T cell clones possess the potential to differentiate into both high- and low-avidity effector cells.
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Academic Article
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Cutting edge: Dendritic cells prime a high avidity CTL response independent of the level of presented antigen.
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Academic Article
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Dose-dependent lymphocyte apoptosis following respiratory infection with Vaccinia virus.
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Academic Article
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Pivotal Advance: Nonfunctional lung effectors exhibit decreased calcium mobilization associated with reduced expression of ORAI1.
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Academic Article
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IFNgamma-producing, virus-specific CD8+ effector cells acquire the ability to produce IL-10 as a result of entry into the infected lung environment.
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Academic Article
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Differentiation-dependent differences in murine T cell susceptibility to negative regulation by the lung.
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Academic Article
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Changes in functional but not structural avidity during differentiation of CD8+ effector cells in vivo after virus infection.
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Academic Article
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Omega-3 fatty acids ameliorate atherosclerosis by favorably altering monocyte subsets and limiting monocyte recruitment to aortic lesions.
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Academic Article
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Specific prolongation of allograft survival by a T-cell-receptor-derived peptide.
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Academic Article
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Biased T cell receptor usage by Ld-restricted, tum- peptide-specific cytotoxic T lymphocyte clones.
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Academic Article
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Target cell lysis by CTL granule exocytosis is independent of ICE/Ced-3 family proteases.
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Academic Article
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Supraoptimal peptide-major histocompatibility complex causes a decrease in bc1-2 levels and allows tumor necrosis factor alpha receptor II-mediated apoptosis of cytotoxic T lymphocytes.
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Academic Article
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An abrupt and concordant initiation of apoptosis: antigen-dependent death of CD8+ CTL.
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Academic Article
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High avidity cytotoxic T lymphocytes to a foreign antigen are efficiently activated following immunization with a recombinant paramyxovirus, simian virus 5.
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Academic Article
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Suppressed cytotoxic T lymphocyte responses in experimental cysticercosis.
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Academic Article
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Optimal colocalization of TCR and CD8 as a novel mechanism for the control of functional avidity.
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Academic Article
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High avidity CD8+ T cells are the initial population elicited following viral infection of the respiratory tract.
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Academic Article
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Altered function in CD8+ T cells following paramyxovirus infection of the respiratory tract.
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Academic Article
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Ligation of CD80 is critical for high-level CD25 expression on CD8+ T lymphocytes.
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Academic Article
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Dose-dependent modulation of CD8 and functional avidity as a result of peptide encounter.
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Academic Article
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Loss of function in virus-specific lung effector T cells is independent of infection.
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Academic Article
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Regulation of maturation and activating potential in CD8+ versus CD8- dendritic cells following in vivo infection with vaccinia virus.
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Academic Article
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Functional divergence among CD103+ dendritic cell subpopulations following pulmonary poxvirus infection.
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Academic Article
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Increased sensitivity to antigen in high avidity CD8(+) T cells results from augmented membrane proximal T-cell receptor signal transduction.
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Academic Article
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CD8 marks a subpopulation of lung-derived dendritic cells with differential responsiveness to viral infection and toll-like receptor stimulation.
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Academic Article
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Alloreactive cytotoxic T lymphocytes generated in the presence of viral-derived peptides show exquisite peptide and MHC specificity.
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Academic Article
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Selective expansion of high- or low-avidity cytotoxic T lymphocytes and efficacy for adoptive immunotherapy.
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Academic Article
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Role of antigen, CD8, and cytotoxic T lymphocyte (CTL) avidity in high dose antigen induction of apoptosis of effector CTL.
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Academic Article
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Cytotoxic T lymphocyte (CTL) adherence assay (CAA): a non-radioactive assay for murine CTL recognition of peptide-MHC class I complexes.
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Academic Article
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Differential expansion and survival of high and low avidity cytotoxic T cell populations during the immune response to a viral infection.
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Concept
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Mice, Knockout
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Concept
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Mice, Inbred C3H
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Concept
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Mice
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Concept
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Mice, Inbred C57BL
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Concept
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Mice, Transgenic
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Concept
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Mice, Inbred BALB C
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Concept
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Mice, Nude
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Concept
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Mice, SCID
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Concept
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Mice, Inbred Strains
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Concept
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Mice, Inbred DBA
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Academic Article
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High viral burden restricts short-lived effector cell number at late times postinfection through increased natural regulatory T cell expansion.
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Academic Article
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In vivo modulation of avidity in highly sensitive CD8(+) effector T cells following viral infection.
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Academic Article
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CD4+ T cell subset differentiation and avidity setpoint are dictated by the interplay of cytokine and antigen mediated signals.
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Academic Article
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Influenza A virus alters pneumococcal nasal colonization and middle ear infection independently of phase variation.
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Academic Article
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Coinfection with Streptococcus pneumoniae negatively modulates the size and composition of the ongoing influenza-specific CD8? T cell response.
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Academic Article
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Correlation between CD8 dependency and determinant density using peptide-induced, Ld-restricted cytotoxic T lymphocytes.
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Academic Article
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Deregulated Bcl-2 gene expression selectively prolongs survival of growth factor-deprived hemopoietic cell lines.
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Academic Article
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In vivo activation of leukocyte GPR120/FFAR4 by PUFAs has minimal impact on atherosclerosis in LDL receptor knockout mice.
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Academic Article
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Pneumococcal Neuraminidase A (NanA) Promotes Biofilm Formation and Synergizes with Influenza A Virus in Nasal Colonization and Middle Ear Infection.
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Grant
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Control of T cell response during respiratory infection
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Grant
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Control of cytotoxic T cell differentiation and activity
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Grant
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Vaccination strategies to overcome immune deficiencies in neonates
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Grant
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CTL AVIDITY AND THE AGING IMMUNE RESPONSE
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Academic Article
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Potential therapeutic action of nitrite in sickle cell disease.
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Academic Article
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Sirtuin1 Targeting Reverses Innate and Adaptive Immune Tolerance in Septic Mice.
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Academic Article
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The choice of linker for conjugating R848 to inactivated influenza virus determines the stimulatory capacity for innate immune cells.
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Academic Article
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TCR Dependent Metabolic Programming Regulates Autocrine IL-4 Production Resulting in Self-Tuning of the CD8+ T Cell Activation Setpoint.
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Academic Article
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Targeting the CD47/thrombospondin-1 signaling axis regulates immune cell bioenergetics in the tumor microenvironment to potentiate antitumor immune response.
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