| Item Type | Name |
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Academic Article
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Peptide requirement for CTL activation reflects the sensitivity to CD3 engagement: correlation with CD8alphabeta versus CD8alphaalpha expression.
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Academic Article
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A novel CD8-independent high-avidity cytotoxic T-lymphocyte response directed against an epitope in the phosphoprotein of the paramyxovirus simian virus 5.
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Academic Article
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Molecular mechanisms and biological significance of CTL avidity.
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Academic Article
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High avidity CD8+ T cells generated from CD28-deficient or wildtype mice exhibit a differential dependence on lipid raft integrity for activation.
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Academic Article
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Modulation of CD8+ T cell avidity by increasing the turnover of viral antigen during infection.
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Academic Article
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Abortive versus productive viral infection of dendritic cells with a paramyxovirus results in differential upregulation of select costimulatory molecules.
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Academic Article
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Vaccinia virus infection of mature dendritic cells results in activation of virus-specific naïve CD8+ T cells: a potential mechanism for direct presentation.
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Academic Article
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Distinct pathways for signaling maturation in macrophages and dendritic cells after infection with paramyxovirus simian virus 5.
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Academic Article
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Cutting edge: CD8+ T cell clones possess the potential to differentiate into both high- and low-avidity effector cells.
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Academic Article
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Cutting edge: Dendritic cells prime a high avidity CTL response independent of the level of presented antigen.
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Academic Article
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IFNgamma-producing, virus-specific CD8+ effector cells acquire the ability to produce IL-10 as a result of entry into the infected lung environment.
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Academic Article
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Changes in functional but not structural avidity during differentiation of CD8+ effector cells in vivo after virus infection.
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Academic Article
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Omega-3 fatty acids ameliorate atherosclerosis by favorably altering monocyte subsets and limiting monocyte recruitment to aortic lesions.
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Academic Article
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Specific prolongation of allograft survival by a T-cell-receptor-derived peptide.
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Academic Article
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Biased T cell receptor usage by Ld-restricted, tum- peptide-specific cytotoxic T lymphocyte clones.
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Academic Article
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Supraoptimal peptide-major histocompatibility complex causes a decrease in bc1-2 levels and allows tumor necrosis factor alpha receptor II-mediated apoptosis of cytotoxic T lymphocytes.
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Academic Article
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An abrupt and concordant initiation of apoptosis: antigen-dependent death of CD8+ CTL.
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Academic Article
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High avidity cytotoxic T lymphocytes to a foreign antigen are efficiently activated following immunization with a recombinant paramyxovirus, simian virus 5.
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Academic Article
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Optimal colocalization of TCR and CD8 as a novel mechanism for the control of functional avidity.
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Academic Article
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Altered function in CD8+ T cells following paramyxovirus infection of the respiratory tract.
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Academic Article
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Ligation of CD80 is critical for high-level CD25 expression on CD8+ T lymphocytes.
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Academic Article
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Dose-dependent modulation of CD8 and functional avidity as a result of peptide encounter.
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Academic Article
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Regulation of maturation and activating potential in CD8+ versus CD8- dendritic cells following in vivo infection with vaccinia virus.
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Academic Article
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Engineered expression of the TLR5 ligand flagellin enhances paramyxovirus activation of human dendritic cell function.
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Academic Article
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Functional divergence among CD103+ dendritic cell subpopulations following pulmonary poxvirus infection.
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Academic Article
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Increased sensitivity to antigen in high avidity CD8(+) T cells results from augmented membrane proximal T-cell receptor signal transduction.
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Academic Article
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Virion-associated complement regulator CD55 is more potent than CD46 in mediating resistance of mumps virus and vesicular stomatitis virus to neutralization.
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Academic Article
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CD8 marks a subpopulation of lung-derived dendritic cells with differential responsiveness to viral infection and toll-like receptor stimulation.
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Academic Article
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Alloreactive cytotoxic T lymphocytes generated in the presence of viral-derived peptides show exquisite peptide and MHC specificity.
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Academic Article
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Expression of HLA class I molecules and the transporter associated with antigen processing in hepatocellular carcinoma.
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Academic Article
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Selective expansion of high- or low-avidity cytotoxic T lymphocytes and efficacy for adoptive immunotherapy.
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Academic Article
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Molecular analysis of presentation by HLA-A2.1 of a promiscuously binding V3 loop peptide from the HIV-envelope protein to human cytotoxic T lymphocytes.
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Academic Article
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Role of antigen, CD8, and cytotoxic T lymphocyte (CTL) avidity in high dose antigen induction of apoptosis of effector CTL.
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Academic Article
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Cytotoxic T lymphocyte (CTL) adherence assay (CAA): a non-radioactive assay for murine CTL recognition of peptide-MHC class I complexes.
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Concept
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Antigens, Differentiation, T-Lymphocyte
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Concept
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Antigen Presentation
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Concept
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Antigens, Surface
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Concept
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Antigens, Viral
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Concept
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Antigens, Neoplasm
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Concept
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Gene Rearrangement, alpha-Chain T-Cell Antigen Receptor
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Concept
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Histocompatibility Antigens Class I
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Concept
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HLA-A2 Antigen
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Concept
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Antigens, Bacterial
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Concept
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Antigens, CD
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Concept
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Antigens, Ly
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Concept
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HIV Antigens
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Concept
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Receptors, Antigen, T-Cell, alpha-beta
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Concept
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Antigens
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Concept
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Receptors, Antigen, T-Cell
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Concept
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Histocompatibility Antigens Class II
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Concept
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Antigen-Presenting Cells
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Concept
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H-2 Antigens
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Concept
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Histocompatibility Antigens
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Academic Article
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High viral burden restricts short-lived effector cell number at late times postinfection through increased natural regulatory T cell expansion.
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Academic Article
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In vivo modulation of avidity in highly sensitive CD8(+) effector T cells following viral infection.
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Academic Article
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CD4+ T cell subset differentiation and avidity setpoint are dictated by the interplay of cytokine and antigen mediated signals.
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Academic Article
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Correlation between CD8 dependency and determinant density using peptide-induced, Ld-restricted cytotoxic T lymphocytes.
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Grant
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Control of T cell response during respiratory infection
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Grant
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Control of cytotoxic T cell differentiation and activity
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Grant
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CTL AVIDITY AND THE AGING IMMUNE RESPONSE
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Academic Article
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Higher Frequency and Increased Expression of Molecules Associated with Suppression on T Regulatory Cells from Newborn Compared with Adult Nonhuman Primates.
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Academic Article
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TCR Dependent Metabolic Programming Regulates Autocrine IL-4 Production Resulting in Self-Tuning of the CD8+ T Cell Activation Setpoint.
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Academic Article
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Targeting the CD47/thrombospondin-1 signaling axis regulates immune cell bioenergetics in the tumor microenvironment to potentiate antitumor immune response.
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