| Item Type | Name |
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Academic Article
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Activity of one of two engineered heterodimers of AhpF, the NADH:peroxiredoxin oxidoreductase from Salmonella typhimurium, reveals intrasubunit electron transfer between domains.
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Academic Article
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Identification of a peroxide-sensitive redox switch at the CXXC motif in the human mitochondrial branched chain aminotransferase.
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Academic Article
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Peroxiredoxin evolution and the regulation of hydrogen peroxide signaling.
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Academic Article
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Protein sulfenic acids in redox signaling.
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Academic Article
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Conformational and oligomeric effects on the cysteine pK(a) of tryparedoxin peroxidase.
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Academic Article
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Use of dimedone-based chemical probes for sulfenic acid detection methods to visualize and identify labeled proteins.
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Academic Article
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Structural evidence that peroxiredoxin catalytic power is based on transition-state stabilization.
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Academic Article
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Cysteine-based redox switches in enzymes.
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Academic Article
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Formation and functions of protein sulfenic acids.
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Academic Article
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Structure-based insights into the catalytic power and conformational dexterity of peroxiredoxins.
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Academic Article
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Crystal structure of alkyl hydroperoxidase D like protein PA0269 from Pseudomonas aeruginosa: homology of the AhpD-like structural family.
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Academic Article
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Overview of peroxiredoxins in oxidant defense and redox regulation.
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Academic Article
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Peroxiredoxins in parasites.
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Academic Article
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Structural and electrostatic asymmetry at the active site in typical and atypical peroxiredoxin dimers.
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Academic Article
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AhpF can be dissected into two functional units: tandem repeats of two thioredoxin-like folds in the N-terminus mediate electron transfer from the thioredoxin reductase-like C-terminus to AhpC.
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Academic Article
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An NADH-dependent bacterial thioredoxin reductase-like protein in conjunction with a glutaredoxin homologue form a unique peroxiredoxin (AhpC) reducing system in Clostridium pasteurianum.
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Academic Article
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Dimers to doughnuts: redox-sensitive oligomerization of 2-cysteine peroxiredoxins.
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Academic Article
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An iron-binding protein, Dpr, from Streptococcus mutans prevents iron-dependent hydroxyl radical formation in vitro.
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Academic Article
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Catalytic mechanism of thiol peroxidase from Escherichia coli. Sulfenic acid formation and overoxidation of essential CYS61.
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Academic Article
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Structure, mechanism and regulation of peroxiredoxins.
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Academic Article
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Hydroxyapatite chromatography: altering the phosphate-dependent elution profile of protein as a function of pH.
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Academic Article
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Roles for cysteine residues in the regulatory CXXC motif of human mitochondrial branched chain aminotransferase enzyme.
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Academic Article
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Bacterial defenses against oxidants: mechanistic features of cysteine-based peroxidases and their flavoprotein reductases.
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Academic Article
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Structural basis for the retroreduction of inactivated peroxiredoxins by human sulfiredoxin.
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Academic Article
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Oxidized and synchrotron cleaved structures of the disulfide redox center in the N-terminal domain of Salmonella typhimurium AhpF.
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Academic Article
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Cysteine reactivity and thiol-disulfide interchange pathways in AhpF and AhpC of the bacterial alkyl hydroperoxide reductase system.
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Academic Article
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The requirement of reversible cysteine sulfenic acid formation for T cell activation and function.
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Academic Article
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The catalytic mechanism of peroxiredoxins.
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Academic Article
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Mutant AhpC peroxiredoxins suppress thiol-disulfide redox deficiencies and acquire deglutathionylating activity.
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Academic Article
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Functional site profiling and electrostatic analysis of cysteines modifiable to cysteine sulfenic acid.
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Academic Article
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Cysteine pK(a) values for the bacterial peroxiredoxin AhpC.
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Academic Article
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Redox-dependent dynamics of a dual thioredoxin fold protein: evolution of specialized folds.
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Academic Article
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Structural changes common to catalysis in the Tpx peroxiredoxin subfamily.
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Academic Article
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Water-soluble triarylphosphines as biomarkers for protein S-nitrosation.
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Academic Article
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Engineering of fluorescent reporters into redox domains to monitor electron transfers.
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Academic Article
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Measurement of protein sulfenic acid content.
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Academic Article
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PREX: PeroxiRedoxin classification indEX, a database of subfamily assignments across the diverse peroxiredoxin family.
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Academic Article
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Isoform-specific regulation of Akt by PDGF-induced reactive oxygen species.
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Academic Article
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Kinetic and thermodynamic features reveal that Escherichia coli BCP is an unusually versatile peroxiredoxin.
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Academic Article
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The reversible formation of cysteine sulfenic acid promotes B-cell activation and proliferation.
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Academic Article
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Electrostatics of cysteine residues in proteins: parameterization and validation of a simple model.
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Academic Article
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Vascular bioactivation of nitroglycerin by aldehyde dehydrogenase-2: reaction intermediates revealed by crystallography and mass spectrometry.
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Academic Article
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Attachment of the N-terminal domain of Salmonella typhimurium AhpF to Escherichia coli thioredoxin reductase confers AhpC reductase activity but does not affect thioredoxin reductase activity.
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Concept
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Protein Structure, Tertiary
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Concept
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Protein Multimerization
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Concept
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Protein Stability
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Concept
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Protein Structure, Quaternary
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Concept
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Protein Tyrosine Phosphatase, Non-Receptor Type 6
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Concept
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Mitogen-Activated Protein Kinase 1
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Concept
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Protein Interaction Mapping
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Concept
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Mitogen-Activated Protein Kinase 9
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Concept
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Protein Tyrosine Phosphatase, Non-Receptor Type 11
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Concept
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Protein Denaturation
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Concept
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Mitogen-Activated Protein Kinase 3
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Concept
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Protein Structure, Secondary
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Concept
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Protein Binding
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Concept
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Protein Subunits
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Concept
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Protein Transport
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Concept
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Protein Folding
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Concept
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Protein Processing, Post-Translational
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Concept
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Mitogen-Activated Protein Kinases
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Concept
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Protein Tyrosine Phosphatase, Non-Receptor Type 1
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Concept
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Protein Isoforms
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Concept
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Protein Conformation
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Concept
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Databases, Protein
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Concept
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Sequence Analysis, Protein
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Concept
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Protein Engineering
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Academic Article
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Thiol-blocking electrophiles interfere with labeling and detection of protein sulfenic acids.
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Academic Article
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The sensitive balance between the fully folded and locally unfolded conformations of a model peroxiredoxin.
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Academic Article
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Chemical approaches to detect and analyze protein sulfenic acids.
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Academic Article
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Endosomal H2O2 production leads to localized cysteine sulfenic acid formation on proteins during lysophosphatidic acid-mediated cell signaling.
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Academic Article
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Nitration transforms a sensitive peroxiredoxin 2 into a more active and robust peroxidase.
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Academic Article
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Strained cycloalkynes as new protein sulfenic acid traps.
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Academic Article
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Tuning of peroxiredoxin catalysis for various physiological roles.
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Academic Article
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Dissecting peroxiredoxin catalysis: separating binding, peroxidation, and resolution for a bacterial AhpC.
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Academic Article
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Cysteine-Mediated Redox Regulation of Cell Signaling in Chondrocytes Stimulated With Fibronectin Fragments.
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Academic Article
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Distribution and Features of the Six Classes of Peroxiredoxins.
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Academic Article
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X-ray structures of thioredoxin and thioredoxin reductase from Entamoeba histolytica and prevailing hypothesis of the mechanism of Auranofin action.
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Academic Article
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Structural changes upon peroxynitrite-mediated nitration of peroxiredoxin 2; nitrated Prx2 resembles its disulfide-oxidized form.
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Academic Article
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Oxidative Stress Promotes Peroxiredoxin Hyperoxidation and Attenuates Pro-survival Signaling in Aging Chondrocytes.
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Academic Article
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An Atlas of Peroxiredoxins Created Using an Active Site Profile-Based Approach to Functionally Relevant Clustering of Proteins.
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Grant
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New Reagents for Tracking Protein Oxidation in Cells by MS and Imaging Methods
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Grant
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2012 Thiol-based Redox Regulation &Signaling GRC and GRS
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Grant
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Proteomic Profiling of Cancer-Related Redox Signaling Pathways
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Grant
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Profiling of Redox-Sensitive Signaling Proteins
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Grant
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Mechanisms and Regulation of Peroxiredoxins
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Academic Article
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The SAMHD1 dNTP Triphosphohydrolase Is Controlled by a Redox Switch.
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Academic Article
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Endogenous, regulatory cysteine sulfenylation of ERK kinases in response to proliferative signals.
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Academic Article
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SVM-SulfoSite: A support vector machine based predictor for sulfenylation sites.
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Academic Article
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Mitochondria-targeted Probes for Imaging Protein Sulfenylation.
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Academic Article
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Chaperone activation and client binding of a 2-cysteine peroxiredoxin.
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Academic Article
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NOX4 (NADPH Oxidase 4) and Poldip2 (Polymerase d-Interacting Protein 2) Induce Filamentous Actin Oxidation and Promote Its Interaction With Vinculin During Integrin-Mediated Cell Adhesion.
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Academic Article
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Redox proteins.
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Academic Article
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H2O2 oxidation of cysteine residues in c-Jun N-terminal kinase 2 (JNK2) contributes to redox regulation in human articular chondrocytes.
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Academic Article
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Triphenylphosphonium-Derived Protein Sulfenic Acid Trapping Agents: Synthesis, Reactivity, and Effect on Mitochondrial Function.
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Academic Article
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Unraveling the effects of peroxiredoxin 2 nitration; role of C-terminal tyrosine 193.
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Academic Article
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Differential peroxiredoxin hyperoxidation regulates MAP kinase signaling in human articular chondrocytes.
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Grant
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Redox Regulation of Cysteine-Dependent Peroxidases and Signal Transduction Pathways
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Academic Article
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Introduction to approaches and tools for the evaluation of protein cysteine oxidation.
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Academic Article
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[18F]Fluoro-DCP, a first generation PET radiotracer for monitoring protein sulfenylation in vivo.
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Academic Article
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Native state fluctuations in a peroxiredoxin active site match motions needed for catalysis.
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Academic Article
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Nuclear-localized, iron-bound superoxide dismutase-2 antagonizes epithelial lineage programs to promote stemness of breast cancer cells via a histone demethylase activity.
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