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One or more keywords matched the following items that are connected to Poole, Leslie
Item TypeName
Academic Article Activity of one of two engineered heterodimers of AhpF, the NADH:peroxiredoxin oxidoreductase from Salmonella typhimurium, reveals intrasubunit electron transfer between domains.
Academic Article Identification of a peroxide-sensitive redox switch at the CXXC motif in the human mitochondrial branched chain aminotransferase.
Academic Article Peroxiredoxin evolution and the regulation of hydrogen peroxide signaling.
Academic Article Protein sulfenic acids in redox signaling.
Academic Article Conformational and oligomeric effects on the cysteine pK(a) of tryparedoxin peroxidase.
Academic Article Use of dimedone-based chemical probes for sulfenic acid detection methods to visualize and identify labeled proteins.
Academic Article Structural evidence that peroxiredoxin catalytic power is based on transition-state stabilization.
Academic Article Cysteine-based redox switches in enzymes.
Academic Article Formation and functions of protein sulfenic acids.
Academic Article Structure-based insights into the catalytic power and conformational dexterity of peroxiredoxins.
Academic Article Crystal structure of alkyl hydroperoxidase D like protein PA0269 from Pseudomonas aeruginosa: homology of the AhpD-like structural family.
Academic Article Overview of peroxiredoxins in oxidant defense and redox regulation.
Academic Article Peroxiredoxins in parasites.
Academic Article Structural and electrostatic asymmetry at the active site in typical and atypical peroxiredoxin dimers.
Academic Article AhpF can be dissected into two functional units: tandem repeats of two thioredoxin-like folds in the N-terminus mediate electron transfer from the thioredoxin reductase-like C-terminus to AhpC.
Academic Article An NADH-dependent bacterial thioredoxin reductase-like protein in conjunction with a glutaredoxin homologue form a unique peroxiredoxin (AhpC) reducing system in Clostridium pasteurianum.
Academic Article Dimers to doughnuts: redox-sensitive oligomerization of 2-cysteine peroxiredoxins.
Academic Article An iron-binding protein, Dpr, from Streptococcus mutans prevents iron-dependent hydroxyl radical formation in vitro.
Academic Article Catalytic mechanism of thiol peroxidase from Escherichia coli. Sulfenic acid formation and overoxidation of essential CYS61.
Academic Article Structure, mechanism and regulation of peroxiredoxins.
Academic Article Hydroxyapatite chromatography: altering the phosphate-dependent elution profile of protein as a function of pH.
Academic Article Roles for cysteine residues in the regulatory CXXC motif of human mitochondrial branched chain aminotransferase enzyme.
Academic Article Bacterial defenses against oxidants: mechanistic features of cysteine-based peroxidases and their flavoprotein reductases.
Academic Article Structural basis for the retroreduction of inactivated peroxiredoxins by human sulfiredoxin.
Academic Article Oxidized and synchrotron cleaved structures of the disulfide redox center in the N-terminal domain of Salmonella typhimurium AhpF.
Academic Article Cysteine reactivity and thiol-disulfide interchange pathways in AhpF and AhpC of the bacterial alkyl hydroperoxide reductase system.
Academic Article The requirement of reversible cysteine sulfenic acid formation for T cell activation and function.
Academic Article The catalytic mechanism of peroxiredoxins.
Academic Article Mutant AhpC peroxiredoxins suppress thiol-disulfide redox deficiencies and acquire deglutathionylating activity.
Academic Article Functional site profiling and electrostatic analysis of cysteines modifiable to cysteine sulfenic acid.
Academic Article Cysteine pK(a) values for the bacterial peroxiredoxin AhpC.
Academic Article Redox-dependent dynamics of a dual thioredoxin fold protein: evolution of specialized folds.
Academic Article Structural changes common to catalysis in the Tpx peroxiredoxin subfamily.
Academic Article Water-soluble triarylphosphines as biomarkers for protein S-nitrosation.
Academic Article Engineering of fluorescent reporters into redox domains to monitor electron transfers.
Academic Article Measurement of protein sulfenic acid content.
Academic Article PREX: PeroxiRedoxin classification indEX, a database of subfamily assignments across the diverse peroxiredoxin family.
Academic Article Isoform-specific regulation of Akt by PDGF-induced reactive oxygen species.
Academic Article Kinetic and thermodynamic features reveal that Escherichia coli BCP is an unusually versatile peroxiredoxin.
Academic Article The reversible formation of cysteine sulfenic acid promotes B-cell activation and proliferation.
Academic Article Electrostatics of cysteine residues in proteins: parameterization and validation of a simple model.
Academic Article Vascular bioactivation of nitroglycerin by aldehyde dehydrogenase-2: reaction intermediates revealed by crystallography and mass spectrometry.
Academic Article Attachment of the N-terminal domain of Salmonella typhimurium AhpF to Escherichia coli thioredoxin reductase confers AhpC reductase activity but does not affect thioredoxin reductase activity.
Concept Protein Structure, Tertiary
Concept Protein Multimerization
Concept Protein Stability
Concept Protein Structure, Quaternary
Concept Protein Tyrosine Phosphatase, Non-Receptor Type 6
Concept Mitogen-Activated Protein Kinase 1
Concept Protein Interaction Mapping
Concept Mitogen-Activated Protein Kinase 9
Concept Protein Tyrosine Phosphatase, Non-Receptor Type 11
Concept Protein Denaturation
Concept Mitogen-Activated Protein Kinase 3
Concept Protein Structure, Secondary
Concept Protein Binding
Concept Protein Subunits
Concept Protein Transport
Concept Protein Folding
Concept Protein Processing, Post-Translational
Concept Mitogen-Activated Protein Kinases
Concept Protein Tyrosine Phosphatase, Non-Receptor Type 1
Concept Protein Isoforms
Concept Protein Conformation
Concept Databases, Protein
Concept Sequence Analysis, Protein
Concept Protein Engineering
Academic Article Thiol-blocking electrophiles interfere with labeling and detection of protein sulfenic acids.
Academic Article The sensitive balance between the fully folded and locally unfolded conformations of a model peroxiredoxin.
Academic Article Chemical approaches to detect and analyze protein sulfenic acids.
Academic Article Endosomal H2O2 production leads to localized cysteine sulfenic acid formation on proteins during lysophosphatidic acid-mediated cell signaling.
Academic Article Nitration transforms a sensitive peroxiredoxin 2 into a more active and robust peroxidase.
Academic Article Strained cycloalkynes as new protein sulfenic acid traps.
Academic Article Tuning of peroxiredoxin catalysis for various physiological roles.
Academic Article Dissecting peroxiredoxin catalysis: separating binding, peroxidation, and resolution for a bacterial AhpC.
Academic Article Cysteine-Mediated Redox Regulation of Cell Signaling in Chondrocytes Stimulated With Fibronectin Fragments.
Academic Article Distribution and Features of the Six Classes of Peroxiredoxins.
Academic Article X-ray structures of thioredoxin and thioredoxin reductase from Entamoeba histolytica and prevailing hypothesis of the mechanism of Auranofin action.
Academic Article Structural changes upon peroxynitrite-mediated nitration of peroxiredoxin 2; nitrated Prx2 resembles its disulfide-oxidized form.
Academic Article Oxidative Stress Promotes Peroxiredoxin Hyperoxidation and Attenuates Pro-survival Signaling in Aging Chondrocytes.
Academic Article An Atlas of Peroxiredoxins Created Using an Active Site Profile-Based Approach to Functionally Relevant Clustering of Proteins.
Grant New Reagents for Tracking Protein Oxidation in Cells by MS and Imaging Methods
Grant 2012 Thiol-based Redox Regulation &Signaling GRC and GRS
Grant Proteomic Profiling of Cancer-Related Redox Signaling Pathways
Grant Profiling of Redox-Sensitive Signaling Proteins
Grant Mechanisms and Regulation of Peroxiredoxins
Academic Article The SAMHD1 dNTP Triphosphohydrolase Is Controlled by a Redox Switch.
Academic Article Endogenous, regulatory cysteine sulfenylation of ERK kinases in response to proliferative signals.
Academic Article SVM-SulfoSite: A support vector machine based predictor for sulfenylation sites.
Academic Article Mitochondria-targeted Probes for Imaging Protein Sulfenylation.
Academic Article Chaperone activation and client binding of a 2-cysteine peroxiredoxin.
Academic Article NOX4 (NADPH Oxidase 4) and Poldip2 (Polymerase d-Interacting Protein 2) Induce Filamentous Actin Oxidation and Promote Its Interaction With Vinculin During Integrin-Mediated Cell Adhesion.
Academic Article Redox proteins.
Academic Article H2O2 oxidation of cysteine residues in c-Jun N-terminal kinase 2 (JNK2) contributes to redox regulation in human articular chondrocytes.
Academic Article Triphenylphosphonium-Derived Protein Sulfenic Acid Trapping Agents: Synthesis, Reactivity, and Effect on Mitochondrial Function.
Academic Article Unraveling the effects of peroxiredoxin 2 nitration; role of C-terminal tyrosine 193.
Academic Article Differential peroxiredoxin hyperoxidation regulates MAP kinase signaling in human articular chondrocytes.
Grant Redox Regulation of Cysteine-Dependent Peroxidases and Signal Transduction Pathways
Academic Article Introduction to approaches and tools for the evaluation of protein cysteine oxidation.
Academic Article [18F]Fluoro-DCP, a first generation PET radiotracer for monitoring protein sulfenylation in vivo.
Academic Article Native state fluctuations in a peroxiredoxin active site match motions needed for catalysis.
Academic Article Nuclear-localized, iron-bound superoxide dismutase-2 antagonizes epithelial lineage programs to promote stemness of breast cancer cells via a histone demethylase activity.
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  • Staphylococcal Protein A