| Item Type | Name |
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Academic Article
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Identification of a peroxide-sensitive redox switch at the CXXC motif in the human mitochondrial branched chain aminotransferase.
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Academic Article
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Protein sulfenic acids in redox signaling.
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Academic Article
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Analysis of the link between enzymatic activity and oligomeric state in AhpC, a bacterial peroxiredoxin.
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Academic Article
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Synthesis of chemical probes to map sulfenic acid modifications on proteins.
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Academic Article
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Conformational and oligomeric effects on the cysteine pK(a) of tryparedoxin peroxidase.
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Academic Article
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Use of dimedone-based chemical probes for sulfenic acid detection evaluation of conditions affecting probe incorporation into redox-sensitive proteins.
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Academic Article
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Use of dimedone-based chemical probes for sulfenic acid detection methods to visualize and identify labeled proteins.
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Academic Article
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Reactive oxygen species mediate lysophosphatidic acid induced signaling in ovarian cancer cells.
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Academic Article
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Formation and functions of protein sulfenic acids.
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Academic Article
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Analysis of the peroxiredoxin family: using active-site structure and sequence information for global classification and residue analysis.
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Academic Article
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Crystal structure of alkyl hydroperoxidase D like protein PA0269 from Pseudomonas aeruginosa: homology of the AhpD-like structural family.
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Academic Article
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Structural and electrostatic asymmetry at the active site in typical and atypical peroxiredoxin dimers.
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Academic Article
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AhpF can be dissected into two functional units: tandem repeats of two thioredoxin-like folds in the N-terminus mediate electron transfer from the thioredoxin reductase-like C-terminus to AhpC.
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Academic Article
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An NADH-dependent bacterial thioredoxin reductase-like protein in conjunction with a glutaredoxin homologue form a unique peroxiredoxin (AhpC) reducing system in Clostridium pasteurianum.
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Academic Article
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An iron-binding protein, Dpr, from Streptococcus mutans prevents iron-dependent hydroxyl radical formation in vitro.
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Academic Article
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Catalytic mechanism of thiol peroxidase from Escherichia coli. Sulfenic acid formation and overoxidation of essential CYS61.
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Academic Article
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Hydroxyapatite chromatography: altering the phosphate-dependent elution profile of protein as a function of pH.
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Academic Article
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Bacterial defenses against oxidants: mechanistic features of cysteine-based peroxidases and their flavoprotein reductases.
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Academic Article
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Oxidized and synchrotron cleaved structures of the disulfide redox center in the N-terminal domain of Salmonella typhimurium AhpF.
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Academic Article
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Novel organic hydroperoxide-sensing and responding mechanisms for OhrR, a major bacterial sensor and regulator of organic hydroperoxide stress.
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Academic Article
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Fluorescent and affinity-based tools to detect cysteine sulfenic acid formation in proteins.
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Academic Article
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Substrate specificity and redox potential of AhpC, a bacterial peroxiredoxin.
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Academic Article
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Mutant AhpC peroxiredoxins suppress thiol-disulfide redox deficiencies and acquire deglutathionylating activity.
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Academic Article
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Functional site profiling and electrostatic analysis of cysteines modifiable to cysteine sulfenic acid.
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Academic Article
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Cysteine pK(a) values for the bacterial peroxiredoxin AhpC.
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Academic Article
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Redox regulation and trapping sulfenic acid in the peroxide-sensitive human mitochondrial branched chain aminotransferase.
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Academic Article
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Redox-dependent dynamics of a dual thioredoxin fold protein: evolution of specialized folds.
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Academic Article
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Structural changes common to catalysis in the Tpx peroxiredoxin subfamily.
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Academic Article
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Measurement of protein sulfenic acid content.
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Academic Article
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Isoform-specific regulation of Akt by PDGF-induced reactive oxygen species.
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Academic Article
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Simple synthesis of 1,3-cyclopentanedione derived probes for labeling sulfenic acid proteins.
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Academic Article
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Localized cysteine sulfenic acid formation by vascular endothelial growth factor: role in endothelial cell migration and angiogenesis.
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Academic Article
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Kinetic and thermodynamic features reveal that Escherichia coli BCP is an unusually versatile peroxiredoxin.
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Academic Article
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Peroxiredoxins as molecular triage agents, sacrificing themselves to enhance cell survival during a peroxide attack.
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Academic Article
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A simple and effective strategy for labeling cysteine sulfenic acid in proteins by utilization of ß-ketoesters as cleavable probes.
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Academic Article
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A new family of membrane electron transporters and its substrates, including a new cell envelope peroxiredoxin, reveal a broadened reductive capacity of the oxidative bacterial cell envelope.
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Academic Article
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Electrostatics of cysteine residues in proteins: parameterization and validation of a simple model.
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Academic Article
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Vascular bioactivation of nitroglycerin by aldehyde dehydrogenase-2: reaction intermediates revealed by crystallography and mass spectrometry.
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Academic Article
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Attachment of the N-terminal domain of Salmonella typhimurium AhpF to Escherichia coli thioredoxin reductase confers AhpC reductase activity but does not affect thioredoxin reductase activity.
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Academic Article
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AhpF and other NADH:peroxiredoxin oxidoreductases, homologues of low Mr thioredoxin reductase.
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Academic Article
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Essential thioredoxin-dependent peroxiredoxin system from Helicobacter pylori: genetic and kinetic characterization.
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Concept
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Homeodomain Proteins
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Concept
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Escherichia coli Proteins
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Concept
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Bacterial Proteins
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Concept
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Recombinant Fusion Proteins
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Concept
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Bacterial Outer Membrane Proteins
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Concept
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Plant Proteins
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Concept
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Saccharomyces cerevisiae Proteins
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Concept
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Mitochondrial Proteins
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Concept
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Carrier Proteins
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Concept
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Nuclear Proteins
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Concept
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Recombinant Proteins
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Concept
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Mutant Proteins
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Concept
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Iron-Binding Proteins
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Concept
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Repressor Proteins
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Concept
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Schizosaccharomyces pombe Proteins
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Concept
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Proto-Oncogene Proteins c-akt
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Concept
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Proteins
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Concept
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Vesicular Transport Proteins
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Concept
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Periplasmic Proteins
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Concept
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DNA-Binding Proteins
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Concept
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ras GTPase-Activating Proteins
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Concept
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Proto-Oncogene Proteins p21(ras)
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Concept
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Electron Transport Chain Complex Proteins
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Concept
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Transferrin-Binding Proteins
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Concept
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Protozoan Proteins
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Academic Article
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Evaluating peroxiredoxin sensitivity toward inactivation by peroxide substrates.
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Academic Article
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D-alanine modification of a protease-susceptible outer membrane component by the Bordetella pertussis dra locus promotes resistance to antimicrobial peptides and polymorphonuclear leukocyte-mediated killing.
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Academic Article
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Thiol-blocking electrophiles interfere with labeling and detection of protein sulfenic acids.
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Academic Article
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Chemical approaches to detect and analyze protein sulfenic acids.
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Academic Article
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Endosomal H2O2 production leads to localized cysteine sulfenic acid formation on proteins during lysophosphatidic acid-mediated cell signaling.
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Academic Article
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Nitration transforms a sensitive peroxiredoxin 2 into a more active and robust peroxidase.
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Academic Article
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Strained cycloalkynes as new protein sulfenic acid traps.
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Academic Article
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Distribution and Features of the Six Classes of Peroxiredoxins.
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Academic Article
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X-ray structures of thioredoxin and thioredoxin reductase from Entamoeba histolytica and prevailing hypothesis of the mechanism of Auranofin action.
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Academic Article
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Backbone chemical shift assignments for Xanthomonas campestris peroxiredoxin Q in the reduced and oxidized states: a dramatic change in backbone dynamics.
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Academic Article
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Structural changes upon peroxynitrite-mediated nitration of peroxiredoxin 2; nitrated Prx2 resembles its disulfide-oxidized form.
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Academic Article
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Oxidative Stress Promotes Peroxiredoxin Hyperoxidation and Attenuates Pro-survival Signaling in Aging Chondrocytes.
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Academic Article
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Peroxiredoxin Catalysis at Atomic Resolution.
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Academic Article
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An Atlas of Peroxiredoxins Created Using an Active Site Profile-Based Approach to Functionally Relevant Clustering of Proteins.
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Grant
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Mechanistic Studies of Alkyl Hydroperoxide Reductase and Related Redox Proteins
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Grant
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New Reagents for Tracking Protein Oxidation in Cells by MS and Imaging Methods
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Grant
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2012 Thiol-based Redox Regulation &Signaling GRC and GRS
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Grant
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Proteomic Profiling of Cancer-Related Redox Signaling Pathways
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Grant
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2010 Thiol-based Redox Regulation &Signaling Gordon Research Conference
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Grant
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Profiling of Redox-Sensitive Signaling Proteins
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Academic Article
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SVM-SulfoSite: A support vector machine based predictor for sulfenylation sites.
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Academic Article
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Mitochondria-targeted Probes for Imaging Protein Sulfenylation.
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Academic Article
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NOX4 (NADPH Oxidase 4) and Poldip2 (Polymerase d-Interacting Protein 2) Induce Filamentous Actin Oxidation and Promote Its Interaction With Vinculin During Integrin-Mediated Cell Adhesion.
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Academic Article
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Redox proteins.
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Academic Article
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Triphenylphosphonium-Derived Protein Sulfenic Acid Trapping Agents: Synthesis, Reactivity, and Effect on Mitochondrial Function.
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Academic Article
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Differential peroxiredoxin hyperoxidation regulates MAP kinase signaling in human articular chondrocytes.
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Academic Article
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Introduction to approaches and tools for the evaluation of protein cysteine oxidation.
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Academic Article
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Oncogenic KRAS G12C: Kinetic and redox characterization of covalent inhibition.
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Academic Article
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Native state fluctuations in a peroxiredoxin active site match motions needed for catalysis.
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