| Item Type | Name |
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Academic Article
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Identification of cysteine sulfenic acid in AhpC of alkyl hydroperoxide reductase.
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Academic Article
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Peroxiredoxin evolution and the regulation of hydrogen peroxide signaling.
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Academic Article
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Isotope-coded, iodoacetamide-based reagent to determine individual cysteine pK(a) values by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
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Academic Article
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Discovering mechanisms of signaling-mediated cysteine oxidation.
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Academic Article
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Decreasing peroxiredoxin II expression decreases glutathione, alters cell cycle distribution, and sensitizes glioma cells to ionizing radiation and H(2)O(2).
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Academic Article
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Structural evidence that peroxiredoxin catalytic power is based on transition-state stabilization.
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Academic Article
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Structure-based insights into the catalytic power and conformational dexterity of peroxiredoxins.
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Academic Article
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Conformational studies of the robust 2-Cys peroxiredoxin Salmonella typhimurium AhpC by solution phase hydrogen/deuterium (H/D) exchange monitored by electrospray ionization mass spectrometry.
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Academic Article
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Crystal structure of alkyl hydroperoxidase D like protein PA0269 from Pseudomonas aeruginosa: homology of the AhpD-like structural family.
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Academic Article
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Catalytic mechanism of thiol peroxidase from Escherichia coli. Sulfenic acid formation and overoxidation of essential CYS61.
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Academic Article
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Hydroxyapatite chromatography: altering the phosphate-dependent elution profile of protein as a function of pH.
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Academic Article
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Roles for cysteine residues in the regulatory CXXC motif of human mitochondrial branched chain aminotransferase enzyme.
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Academic Article
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Bacterial defenses against oxidants: mechanistic features of cysteine-based peroxidases and their flavoprotein reductases.
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Academic Article
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Novel organic hydroperoxide-sensing and responding mechanisms for OhrR, a major bacterial sensor and regulator of organic hydroperoxide stress.
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Academic Article
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Oxidation state governs structural transitions in peroxiredoxin II that correlate with cell cycle arrest and recovery.
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Academic Article
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Substrate specificity and redox potential of AhpC, a bacterial peroxiredoxin.
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Academic Article
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Mutant AhpC peroxiredoxins suppress thiol-disulfide redox deficiencies and acquire deglutathionylating activity.
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Academic Article
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Functional site profiling and electrostatic analysis of cysteines modifiable to cysteine sulfenic acid.
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Academic Article
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Cysteine pK(a) values for the bacterial peroxiredoxin AhpC.
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Academic Article
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Redox regulation and trapping sulfenic acid in the peroxide-sensitive human mitochondrial branched chain aminotransferase.
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Academic Article
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Typical 2-Cys peroxiredoxins--structures, mechanisms and functions.
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Academic Article
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Extracellular SOD-derived H2O2 promotes VEGF signaling in caveolae/lipid rafts and post-ischemic angiogenesis in mice.
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Academic Article
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Kinetic and thermodynamic features reveal that Escherichia coli BCP is an unusually versatile peroxiredoxin.
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Academic Article
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Peroxiredoxins as molecular triage agents, sacrificing themselves to enhance cell survival during a peroxide attack.
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Concept
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Hydrogen Peroxide
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Concept
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Hydrogen-Ion Concentration
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Concept
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Hydrogen Bonding
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Academic Article
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Endosomal H2O2 production leads to localized cysteine sulfenic acid formation on proteins during lysophosphatidic acid-mediated cell signaling.
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Academic Article
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Nitration transforms a sensitive peroxiredoxin 2 into a more active and robust peroxidase.
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Academic Article
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Dissecting peroxiredoxin catalysis: separating binding, peroxidation, and resolution for a bacterial AhpC.
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Grant
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Mechanistic Studies of Alkyl Hydroperoxide Reductase and Related Redox Proteins
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Grant
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Proteomic Profiling of Cancer-Related Redox Signaling Pathways
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Grant
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Profiling of Redox-Sensitive Signaling Proteins
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Grant
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Mechanisms and Regulation of Peroxiredoxins
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Academic Article
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Experimentally Dissecting the Origins of Peroxiredoxin Catalysis.
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Academic Article
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Endogenous, regulatory cysteine sulfenylation of ERK kinases in response to proliferative signals.
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Academic Article
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Novel hyperoxidation resistance motifs in 2-Cys peroxiredoxins.
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Academic Article
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Differential Kinetics of Two-Cysteine Peroxiredoxin Disulfide Formation Reveal a Novel Model for Peroxide Sensing.
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Academic Article
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NOX4 (NADPH Oxidase 4) and Poldip2 (Polymerase d-Interacting Protein 2) Induce Filamentous Actin Oxidation and Promote Its Interaction With Vinculin During Integrin-Mediated Cell Adhesion.
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Academic Article
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H2O2 oxidation of cysteine residues in c-Jun N-terminal kinase 2 (JNK2) contributes to redox regulation in human articular chondrocytes.
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Academic Article
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Differential peroxiredoxin hyperoxidation regulates MAP kinase signaling in human articular chondrocytes.
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Grant
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Redox Regulation of Cysteine-Dependent Peroxidases and Signal Transduction Pathways
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Academic Article
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Mitigation of doxorubicin-induced cardiotoxicity with an H2O2-Activated, H2S-Donating hybrid prodrug.
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Academic Article
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Native state fluctuations in a peroxiredoxin active site match motions needed for catalysis.
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Academic Article
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Nuclear-localized, iron-bound superoxide dismutase-2 antagonizes epithelial lineage programs to promote stemness of breast cancer cells via a histone demethylase activity.
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Academic Article
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Hydrogen peroxide-dependent oxidation of ERK2 within its D-recruitment site alters its substrate selection.
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